Explore our broad range of versatile ELISA kits and obtain a sensitive, specific, quantitative assessment of diverse disease states including powerful biomarker assays for inflammation, metabolic syndrome and neuroscience. Versatility in a Complete Package ELISA Kits EMD Millipore is a division of Merck KGaA, Darmstadt, Germany
Explore our broad range of versatile ELISA kits and obtain a sensitive, specific, quantitative assessment of diverse disease states including powerful biomarker assays for neuroscience and metabolic syndrome. Featured ELISAs & RIAs include: 1. Neuroscience: Neuropeptide & Neurodegenerative ELISAs 2. Metabolic Biomarker ELISAs 3. Transcription Factor Assay (TFA) ELISAs and 4. Radioimmunoassays (RIAs).
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Explore our broad range of versatile ELISA kits and obtain a sensitive, specific, quantitative assessment of diverse disease states including powerful biomarker assays for inflammation, metabolic syndrome and neuroscience.
Versatility in a Complete PackageELISA Kits
EMD Millipore is a division of Merck KGaA, Darmstadt, Germany
Neuroscience: Neuropeptide & Neurodegenerative ELISA Kits Understanding complex, interconnected nervous system functions and dysfunctions requires reliable quantification
of biomarkers. Trust EMD Millipore’s neuropeptide and neurodegenerative ELISA kits to precisely quantify soluble
biomarkers in sera and lysates. EMD Millipore is the leader in developing neural-specific ELISAs. We offer a growing
EMD Millipore has been the company of choice for single protein detection for many years. By choosing our ELISA (Enzyme-linked Immunosorbent Assay) kits, you’ll add 25+ years of experience in metabolic, neuroscience and cytokine* research.
Our ELISA kits are developed, manufactured and shipped under stringent quality regulations. We understand that many research projects last months, even years, and you need to know that each kit will produce the same results, lot after lot.
You also told us you wanted key metabolic assays to match the World Health Organization (WHO)** standards, and we listened! Several kits now are developed and tested based on prestigious WHO values. Along with smaller and more ecologically- friendly packaging, we are sure you’ll find EMD Millipore’s ELISA portfolio exceeds your research expectations.
* Human and Mouse Cytokine Assays coming soon.
** World Health Organization standards are available and used for final quality control testing.
Other enhanced features include:
• Improved sensitivities for most panels
• 10-kit bulk/space saver options available
• Consistent kit and component storage conditions
Discover the most reliable ELISAs for your research needs.
Cytokine / Chemokine ELISAs
COMING SOON!
Cytokine / Chemokine ELISA Kits
“Cytokine” is a general term used for a diverse group of soluble proteins and
peptides which act as regulators, under both normal and pathological conditions,
to modulate the functional activities of individual cells and tissues. EMD
Millipore is pleased to announce the upcoming launch of cytokine/chemokine
ELISAs. These high-quality, cost-effective kits provide consistent and reliable
measurement for all of your research needs.
Circulating Biomarkers
Description Species Catalogue No.
IL-2 Human Coming Soon
IL-2 Mouse Coming Soon
IL-4 Human Coming Soon
IL-4 Mouse Coming Soon
IL-6 Human Coming Soon
IL-6 Mouse Coming Soon
IL-10 Human Coming Soon
IL-10 Mouse Coming Soon
TNF-α Human Coming Soon
TNF-α Mouse Coming Soon
www.millipore.com/ELISA
Neuroscience
Description SpeciesStandard Curve Range Sensitivity
sICAM-1 Human 6.25-100 ng/mL 2.17 ng / mL 10 µL ECM335
sVCAM-1 Human 3.2–100 ng/mL 0.59 ng/mL 10 µL ECM340
Neuroscience: Neuropeptide & Neurodegenerative ELISA Kits Understanding complex, interconnected nervous system functions and dysfunctions requires reliable
quantification of biomarkers. Trust EMD Millipore’s neuropeptide and neurodegenerative ELISA kits to
precisely quantify soluble biomarkers in sera and lysates. As the leader in developing neural-specific ELISAs,
we offer a growing selection of ELISAs supporting neuroscience research.
Visualize and quantify neurosciencewith validated neural marker antibodies. By integrating the antibody expertise and resources of Calbiochem®, Chemicon®, Upstate®, and Linco®, EMD Millipore is now the leading provider of neuroscience antibodies for the central and peripheral nervous systems. Drive your neuroscience research forward with our vast portfolio of pathway-, cell type-, and state-specific antibodies and neurological disease assays and markers.
Figure 1. Mechanisms by which S100B can promote neurodegeration. When high levels of S100B are secreted by astrocytes, neurodegeneration can result, either by direct activation of reactive oxygen species (ROS) production and oxidative stress, or by indirect stimulation of microglia, causing secretion of proapoptotic cytokines. (Image adapted from Sorci G. et al., Cardiovascular Psychiatry and Neurology, 2010; vol. 2010, Article ID 656481, 13 pages. doi:10.1155/2010/656481).
Figure 2. Plasma from SCZ patients shows higher expression levels of S100B compared to control subjects. S100B was measured in plasma using the Human S100B ELISA (Cat. No. EZHS100B-33K). The sample set was split into two groups (control n=81, SCZ n=80). A non-parametric test (Mann-Whitney) was applied to compare mean values between both groups. A significant difference is observed in the mean values between control and the SCZ group (p=0.003, error bars indicate the standard error of the mean).
0No LPS 1 hr. LPS 2 hr. LPS 4 hr. LPS 8 hr. LPS
0.5
1
1.5
2
2.5
Plasma FGF-23 Levels in LPS Challenged Mice (n=4)
0
0.51
1.52
2.53
3.5
0 hrs. 2 hrs. 4 hrs. 8 hrs.
Serum FGF-23 Levels in LPS Challenged Rats (n=3)
Conc
entr
atio
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S10
0B in
Hum
an P
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a (p
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0
120.00
100.00
80.00
60.00
40.00
20.00
Control Schizophrenia
Mou
se F
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Rat F
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To download the white paper, “S100B as a Biomarker for Ca2+ Signaling Dysregulation in Schizophrenia”, visit:
WHO Standard values matched to the World Health Organization guidelines.* Bulk packaging now available on select kits — more environmentally friendly and saves space.** Available in May, 2012.a chemiluminescent assay
RIAs / ServicesTrusted expertise through every phase.Drug Discovery & Development Services.
EMD Millipore is your premier service provider for advancement of your drug pipeline in confidence from discovery to market. We extend your capabilities by combining our scientific knowledge, regulatory expertise and flexibility and provide trusted, relevant information required for drug discovery and development.