Electrospinning of hydrogels for biomedical applications Gabriel Goetten de Lima a , Sean Lyons a , Declan Devine a,b , Michael J.D. Nugent a , *. a. Athlone Institute of Technology, Materials Research Institute, Athlone, Co. Westmeath, Ireland. b. Rehabilitation Medicine Center, the Mayo clinic, Rochester, MN USA. *Corresponding author. Dr. Michael J.D. Nugent, Tel: +353 (0)90 6468172; e-mail address: [email protected]. The field of biomedical applications for hydrogels requires the development of nanostructures with specific controlled diameter and mechanical properties. Nanofibers are ideally candidates for these advanced requirements, and one of the easiest techniques that can produce one-dimensional nanostructured materials in fibrous form is the electrospinning. This technique provides extremely thin fibres with controlled diameter, highly porous microstructure with interconnected pores; extremely versatile allowing the use of various polymers for tailoring various applications requirements and it is a simple cost-effective method on preparation of scaffolds. In this section, we will discuss recent and specific applications with a focus on their mechanisms. As such, we conclude this section with a discussion on perspectives and future possibilities on this field. Keywords Electrospinning; Hydrogel; Tissue engineering; Drug delivery; Wound healing