Do Magic Mushrooms Do Magic Mushrooms have medicinal value? have medicinal value? Joshua Root Joshua Root
Jan 05, 2016
Do Magic Mushrooms have Do Magic Mushrooms have medicinal value?medicinal value?
Joshua RootJoshua Root
Psilocybin FactsPsilocybin Facts
Contained in many different Contained in many different mushrooms.mushrooms.
Originated in East AfricaOriginated in East Africa serotonin (5-HT)-2A/2C receptor serotonin (5-HT)-2A/2C receptor
agonist agonist ILLEGAL!ILLEGAL!
EffectsEffects
PsilocinPsilocin Duration of 3-8 hoursDuration of 3-8 hours
Effects ContinuedEffects Continued
Physical effectsPhysical effects Increase in heart rateIncrease in heart rate Elevated blood pressureElevated blood pressure Dilated PupilDilated Pupil Nausea Nausea Coldness and weakness in limbsColdness and weakness in limbs
Effects ContinuedEffects Continued
Emotional effectsEmotional effects Strongly dependent on settingStrongly dependent on setting Mood swingsMood swings Exaggeration of mood at ingestionExaggeration of mood at ingestion
Effects ContinuedEffects Continued
Sensory effectsSensory effects VisualVisual AuditoryAuditory SynthesiaSynthesia
stimulation of one sensory or cognitive stimulation of one sensory or cognitive pathway leads to automatic, involuntary pathway leads to automatic, involuntary experiences in a second sensory or cognitive experiences in a second sensory or cognitive pathway pathway
Proposed Medicinal UsesProposed Medicinal Uses
Psychotherapy Psychotherapy 1950’s1950’s
Modern proposalsModern proposals OCDOCD Cluster HeadachesCluster Headaches Body dysmorphic disorder Body dysmorphic disorder
Treatment of OCDTreatment of OCD
OCDOCD 44thth most commonly diagnosed most commonly diagnosed
psychiatric disorderpsychiatric disorder ComplicationsComplications
Depression, suicidal tendencies, panic, Depression, suicidal tendencies, panic, substance abuse, and interpersonal substance abuse, and interpersonal difficultiesdifficulties
Dysregulation of SerotoninDysregulation of Serotonin 5-HT reuptake inhibitors 5-HT reuptake inhibitors
OCD Treatment FindingsOCD Treatment Findings
Dr. Francisco MorenoDr. Francisco Moreno Completely removed symptoms Completely removed symptoms 4-24 hours4-24 hours
JeremyJeremy Fear of contaminationFear of contamination Symptoms relievedSymptoms relieved
Treatment of Cluster Treatment of Cluster HeadachesHeadaches
Triggered by a few different causesTriggered by a few different causes Interruption of sleep pattern, certain Interruption of sleep pattern, certain
medication, abnormal hormone levels, medication, abnormal hormone levels, and heavy smoking and drinking alcoholand heavy smoking and drinking alcohol
ResultsResults 53 participants53 participants
85% aborted attack85% aborted attack 95% reported extension in remission95% reported extension in remission 42% benefited from sub hallucagenic doses42% benefited from sub hallucagenic doses
Treatment of Body Dysmorphic Treatment of Body Dysmorphic DisorderDisorder
Mr. AMr. A Relieved symptomsRelieved symptoms
Mrs. BMrs. B Relieved symptomsRelieved symptoms
Critiques and CommentsCritiques and Comments
Duration of positive resultsDuration of positive results Not a drug that can be used all the Not a drug that can be used all the
timetime Less toxic than aspirinLess toxic than aspirin
http://www.doitnow.org/pages/132.htmlhttp://www.doitnow.org/pages/132.html http://en.wikipedia.org/wiki/http://en.wikipedia.org/wiki/
Psilocybin_mushrooms#Medicinal_usePsilocybin_mushrooms#Medicinal_use http://www.maps.org/research/psilo/azproto.htmlhttp://www.maps.org/research/psilo/azproto.html http://www.ncbi.nlm.nih.gov/pubmed/16801660http://www.ncbi.nlm.nih.gov/pubmed/16801660 http://en.wikipedia.org/wiki/http://en.wikipedia.org/wiki/
Body_dysmorphic_disorderBody_dysmorphic_disorder http://www.msnbc.msn.com/id/16304852/http://www.msnbc.msn.com/id/16304852/ http://news.bbc.co.uk/2/hi/health/6210694.stmhttp://news.bbc.co.uk/2/hi/health/6210694.stm http://www.shroomery.org/6233/Psychedelic-http://www.shroomery.org/6233/Psychedelic-
Mushrooms-Just-another-Drug-or-a-Powerful-Mushrooms-Just-another-Drug-or-a-Powerful-MedicineMedicine