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Polysorbate 20SAFETY DATA SHEET
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according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
4000351.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Polysorbate 20 Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
Tween 20™; Synonyms:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Serious Eye Damage/Eye Irritation, Category 2A
Skin Sensitization, Category 1
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H319: Causes serious eye irritation.
H317: May cause an allergic skin reaction.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
WarningGHS Signal Word:
P264: Wash hands thoroughly after handling.
P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent
authority.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P362+364: Take off contaminated clothing and wash it before reuse.
GHS Precaution Phrases:
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
P337+313: If eye irritation persists, get medical advice/attention.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P333+313: If skin irritation or rash occurs, seek medical advice/attention.
GHS Response Phrases:
GHS Storage and Disposal Phrases:
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Please refer to Section 7 for Storage and Section 13 for Disposal information.
2.3 Causes serious eye irritation.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause an allergic skin reaction.
May cause respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
9005-64-5
TR7400000
Polyoxyethylenesorbitan Monolaurate (polysorbate
20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
100.0 % 500-018-3
NA
No data available.
Section 4. First Aid MeasuresNo data available.Description of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes
examined and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
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6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid raising and breathing dust, and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. 9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan,
monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. 9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan,
monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
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Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
A clear, yellow viscous liquidAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: N.A.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong oxidizing agentsIncompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition Or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Polysorbate 20 - Toxicity Data: Oral LD50 (rat): 36.7 ml/kg; Oral LD50 (hamster): 18 ml/kg; Oral
LD50 (mouse): >33 g/kg; Irritation Data: Skin (human): 15 mg/3D mild;
Information on
Toxicological Effects:
Polysorbate 20 - Investigated as a tumorigen and reproductive effector.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Polysorbate 20 RTECS Number: TR7400000
Chronic Toxicological
Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
9005-64-5 Polyoxyethylenesorbitan Monolaurate (polysorbate 20;
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl)
derivatives)
n.a. n.a. n.a. n.a.
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Polysorbate 20SAFETY DATA SHEET
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12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
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This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
01/09/2015Revision Date:
Multi-region format
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Wash Buffer Concentrate (400X)SAFETY DATA SHEET
12/09/2013Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
4000621.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Wash Buffer Concentrate (400X) Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
Based on evaluation of currently available data this substance or mixture is not classifiable according to GHS.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
GHS Signal Word:
No phrases apply.
GHS Precaution Phrases:
No phrases apply.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
7758-11-4
TC5580000
Potassium phosphate, dibasic 53.0 % 231-834-5
NA
No data available.
7778-77-0
TC6615500
Potassium phosphate, Monobasic 12.9 % 231-913-4
NA
No data available.
7732-18-5
ZC0110000
Water 34.1 % 231-791-2
NA
No data available.
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4.2
Section 4. First Aid MeasuresNo data available.Description of First Aid
Measures:
Ingestion of large amounts can cause abdominal pain, lowered blood pressure, nausea, and
vomiting.
Important Symptoms and
Effects, Both Acute and
Delayed:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes
examined and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
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Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. 7758-11-4 Potassium phosphate, dibasic No data.
No data. No data. 7778-77-0 Potassium phosphate, Monobasic No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. 7758-11-4 Potassium phosphate, dibasic No data.
No data. No data. 7778-77-0 Potassium phosphate, Monobasic No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.4
A clear, colorless solutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
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Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong oxidizing agentsIncompatibility - Materials
To Avoid:
phosphorus oxides
potassium oxides
Hazardous
Decomposition Or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.Information on
Toxicological Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
7758-11-4 Potassium phosphate, dibasic n.a. n.a. n.a. n.a.
7778-77-0 Potassium phosphate, Monobasic n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
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Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
7758-11-4 Potassium phosphate, dibasic No No No
7778-77-0 Potassium phosphate, Monobasic No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
7758-11-4 Potassium phosphate, dibasic CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7778-77-0 Potassium phosphate, Monobasic CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
01/09/2015Revision Date:
Multi-region format
Page 12
05/07/2015Revision:
Page: 1 of 6
Transcription Factor Binding Assay Buffer (4X)SAFETY DATA SHEET
06/04/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100068801.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Binding Assay Buffer (4X) Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Acute Toxicity: Oral, Category 5
Skin Corrosion/Irritation, Category 3
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H303: May be harmful if swallowed.
H316: Causes mild skin irritation.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
WarningGHS Signal Word:
No phrases apply.
GHS Precaution Phrases:
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs, get medical advice/attention.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Causes mild skin irritation.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
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Transcription Factor Binding Assay Buffer (4X)SAFETY DATA SHEET
06/04/2014Supersedes Revision:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
68987-90-6
NA
Nonidet P-40 0.0 -1.0 % NA
NA
Skin Corr. 2: H315
Eye Damage 2: H319
STOT (SE) 3: H335
7365-45-9
TL6809000
HEPES, free acid 0.0 -5.0 % 230-907-9
NA
No data available.
7791-18-6
OM2975000
Magnesium chloride, hexahydrate 0.0 -5.0 % NA
NA
No data available.
7447-40-7
TS8050000
Potassium chloride 0.0 -5.0 % 231-211-8
NA
Acute Tox.(O) 5: H303
Aquatic (A) 3: H402
56-81-5
MA8050000
Glycerol 5.0 -20.0 % 200-289-5
NA
No data available.
7732-18-5
ZC0110000
Water 64.0 -95.0 % 231-791-2
NA
No data available.
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
Emits toxic fumes under fire conditions.Flammable Properties and
Hazards:
5.3
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6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. 68987-90-6 Nonidet P-40 No data.
No data. No data. 7365-45-9 HEPES, free acid No data.
No data. No data. 7791-18-6 Magnesium chloride, hexahydrate No data.
No data. No data. 7447-40-7 Potassium chloride No data.
TWA: 10 mg/m3 ()
STEL: ()
TWA: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. 68987-90-6 Nonidet P-40 No data.
No data. No data. 7365-45-9 HEPES, free acid No data.
No data. No data. 7791-18-6 Magnesium chloride, hexahydrate No data.
No data. No data. 7447-40-7 Potassium chloride No data.
PEL: 15 (dust); 5 (resp.)
mg/m3
TLV: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Work/Hygienic/Maintenan
ce Practices:
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
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Wash thoroughly after handling.
No data available.
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.9
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong bases
strong oxidizing agents
Incompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
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11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Glycerol - Irritation Data: Eyes (rabbit): 500 mg (24h) mild; Skin (rabbit): 500 mg (24h) mild;
Information on
Toxicological Effects:
Glycerol - Investigated as a mutagen, reproductive effector, and tumorigen.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Glycerol RTECS Number: MA8050000
Chronic Toxicological
Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
68987-90-6 Nonidet P-40 n.a. n.a. n.a. n.a.
7365-45-9 HEPES, free acid n.a. n.a. n.a. n.a.
7791-18-6 Magnesium chloride, hexahydrate n.a. n.a. n.a. n.a.
7447-40-7 Potassium chloride n.a. n.a. n.a. n.a.
56-81-5 Glycerol n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
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CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
68987-90-6 Nonidet P-40 No No No
7365-45-9 HEPES, free acid No No No
7791-18-6 Magnesium chloride, hexahydrate No No No
7447-40-7 Potassium chloride No No No
56-81-5 Glycerol No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
68987-90-6 Nonidet P-40 CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7365-45-9 HEPES, free acid CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7791-18-6 Magnesium chloride, hexahydrate CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7447-40-7 Potassium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
56-81-5 Glycerol CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
Multi-region format
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Transcription Factor Antibody Binding Buffer(10X)
SAFETY DATA SHEET
02/28/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100068821.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Antibody Binding Buffer (10X) Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Acute Toxicity: Oral, Category 4
Skin Corrosion/Irritation, Category 2
Serious Eye Damage/Eye Irritation, Category 2
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
WarningGHS Signal Word:
P264: Wash {hands} thoroughly after handling.
P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
GHS Precaution Phrases:
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
P330: Rinse mouth.
P332+313: If skin irritation occurs, get medical advice/attention.
P337+313: If eye irritation persists, get medical advice/attention.
P362+364: Take off contaminated clothing and wash it before reuse.
GHS Response Phrases:
GHS Storage and Disposal Phrases:
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Please refer to Section 7 for Storage and Section 13 for Disposal information.
2.3 Causes serious eye irritation.
Causes skin irritation.
Harmful if swallowed.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation or skin absorption.
May cause an allergic skin reaction.
May cause respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
77-86-1
TY2900000
Trizma base 1.0 -10.0 % 201-064-4
NA
Skin Corr. 2: H315
Eye Damage 2: H319
STOT (SE) 3: H335
7647-14-5
VZ4725000
Sodium chloride 1.0 -15.0 % 231-598-3
NA
No data available.
9005-64-5
TR7400000
Polyoxyethylenesorbitan Monolaurate (polysorbate
20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
0.0 -5.0 % 500-018-3
NA
No data available.
9048-46-8
MT6446000
Bovine Serum Albumin (BSA) 0.0 -5.0 % 232-936-2
NA
Acute Tox.(O) 4: H302
7732-18-5
ZC0110000
Water 65.0 -98.0 % 231-791-2
NA
No data available.
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
In Case of Inhalation:
4.1
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5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. 77-86-1 Trizma base No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan,
monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No data.
No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. 77-86-1 Trizma base No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan,
monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No data.
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No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.63
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong oxidizing agentsIncompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition or
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
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hydrogen chloride gas
nitrogen oxides
sodium oxides
Byproducts:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Trizma base - Toxicity Data: Oral LDLO (rabbit): 1,000 mg/kg; Oral TDLO (mouse): 3,000 mg/kg;
Oral LD50 (rat): >3,000 mg/kg; Oral LD50 (mouse): 5,500 mg/kg; Oral TDLO (rat): 3,000 mg/kg;
Trizma base - Irritation Data: Skin (rabbit): 500 mg severe;
Information on
Toxicological Effects:
Trizma base- Investigated as a reproductive effector.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Trizma base RTECS Number: TY2900000
Chronic Toxicological
Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
77-86-1 Trizma base n.a. n.a. n.a. n.a.
7647-14-5 Sodium chloride n.a. n.a. n.a. n.a.
9005-64-5 Polyoxyethylenesorbitan Monolaurate (polysorbate 20;
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl)
derivatives)
n.a. n.a. n.a. n.a.
9048-46-8 Bovine Serum Albumin (BSA) n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
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Transcription Factor Antibody Binding Buffer(10X)
SAFETY DATA SHEET
02/28/2014Supersedes Revision:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
77-86-1 Trizma base No No Yes-Cat. N106
7647-14-5 Sodium chloride No No No
9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
No No No
9048-46-8 Bovine Serum Albumin (BSA) No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
77-86-1 Trizma base CAA HAP,ODC: HAP; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7647-14-5 Sodium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
9005-64-5 Polyoxyethylenesorbitan Monolaurate
(polysorbate 20; Sorbitan, monododecanoate,
poly(oxy-1,2-ethanediyl) derivatives)
CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
9048-46-8 Bovine Serum Albumin (BSA) CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
Multi-region format
Page 24
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Transcription Factor Goat Anti-Rabbit HRPConjugate
SAFETY DATA SHEET
06/04/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100068841.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Goat Anti-Rabbit HRP Conjugate Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Acute Toxicity: Oral, Category 4
Skin Corrosion/Irritation, Category 3
Respiratory Sensitization, Category 1
Skin Sensitization, Category 1
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H302: Harmful if swallowed.
H316: Causes mild skin irritation.
H317: May cause an allergic skin reaction.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
DangerGHS Signal Word:
P261: Avoid breathing {dust/fume/gas/mist/vapors/spray}.
P264: Wash {hands} thoroughly after handling.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
P285: In case of inadequate ventilation wear respiratory protection.
GHS Precaution Phrases:
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P330: Rinse mouth.
GHS Response Phrases:
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SAFETY DATA SHEET
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P332+313: If skin irritation occurs, get medical advice/attention.
P333+313: If skin irritation or rash occurs, seek medical advice/attention.
P342+311: If experiencing respiratory symptoms call a POISON CENTER or doctor/physician.
P362+364: Take off contaminated clothing and wash it before reuse.
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Causes mild skin irritation.
Harmful if swallowed.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation or skin absorption.
May cause an allergic skin reaction.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause eye or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
77-86-1
TY2900000
Trizma base 0.0 -5.0 % 201-064-4
NA
Skin Corr. 2: H315
Eye Damage 2: H319
STOT (SE) 3: H335
7647-14-5
VZ4725000
Sodium chloride 0.0 -5.0 % 231-598-3
NA
No data available.
9048-46-8
MT6446000
Bovine Serum Albumin (BSA) 0.0 -5.0 % 232-936-2
NA
Acute Tox.(O) 4: H302
NA
NA
Goat Anti-Rabbit HRP Conjugate 0.0 -1.0 % NA
NA
No data available.
56-81-5
MA8050000
Glycerol 20.0 -50.0 % 200-289-5
NA
No data available.
7778-77-0
TC6615500
Potassium phosphate, Monobasic 0.0 -1.0 % 231-913-4
NA
No data available.
1405-41-0
LY2625000
Gentimicin sulfate 0.0 -1.0 % 215-778-9
NA
Skin Sens. 1: H317
Resp. Sens. 1: H334
7732-18-5
ZC0110000
Water 32.0 -80.0 % 231-791-2
NA
No data available.
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SAFETY DATA SHEET
06/04/2014Supersedes Revision:
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
Emits toxic fumes under fire conditions.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. 77-86-1 Trizma base No data.
No data. No data. 7647-14-5 Sodium chloride No data.
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SAFETY DATA SHEET
06/04/2014Supersedes Revision:
No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
No data. No data. NA Goat Anti-Rabbit HRP Conjugate No data.
TWA: 10 mg/m3 ()
STEL: ()
TWA: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 7778-77-0 Potassium phosphate, Monobasic No data.
No data. No data. 1405-41-0 Gentimicin sulfate No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. 77-86-1 Trizma base No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
No data. No data. NA Goat Anti-Rabbit HRP Conjugate No data.
PEL: 15 (dust); 5 (resp.)
mg/m3
TLV: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 7778-77-0 Potassium phosphate, Monobasic No data.
No data. No data. 1405-41-0 Gentimicin sulfate No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.4
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
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SAFETY DATA SHEET
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Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong bases
strong oxidizing agents
Incompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Glycerol - Irritation Data: Eyes (rabbit): 500 mg (24h) mild; Skin (rabbit): 500 mg (24h) mild;
Information on
Toxicological Effects:
Glycerol - Investigated as a mutagen, reproductive effector, and tumorigen.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Glycerol RTECS Number: MA8050000
Chronic Toxicological
Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
77-86-1 Trizma base n.a. n.a. n.a. n.a.
7647-14-5 Sodium chloride n.a. n.a. n.a. n.a.
9048-46-8 Bovine Serum Albumin (BSA) n.a. n.a. n.a. n.a.
NA Goat Anti-Rabbit HRP Conjugate n.a. n.a. n.a. n.a.
56-81-5 Glycerol n.a. n.a. n.a. n.a.
7778-77-0 Potassium phosphate, Monobasic n.a. n.a. n.a. n.a.
1405-41-0 Gentimicin sulfate n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
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SAFETY DATA SHEET
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12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
77-86-1 Trizma base No No Yes-Cat. N106
7647-14-5 Sodium chloride No No No
9048-46-8 Bovine Serum Albumin (BSA) No No No
NA Goat Anti-Rabbit HRP Conjugate No No No
56-81-5 Glycerol No No No
7778-77-0 Potassium phosphate, Monobasic No No No
1405-41-0 Gentimicin sulfate No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
77-86-1 Trizma base CAA HAP,ODC: HAP; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7647-14-5 Sodium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
9048-46-8 Bovine Serum Albumin (BSA) CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
NA Goat Anti-Rabbit HRP Conjugate CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
56-81-5 Glycerol CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7778-77-0 Potassium phosphate, Monobasic CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
1405-41-0 Gentimicin sulfate CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
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SAFETY DATA SHEET
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This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
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Transcription Factor Developing SolutionSAFETY DATA SHEET
06/04/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100068881.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Developing Solution Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Skin Corrosion/Irritation, Category 3
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H316: Causes mild skin irritation.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
WarningGHS Signal Word:
No phrases apply.
GHS Precaution Phrases:
P332+313: If skin irritation occurs, get medical advice/attention.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Causes mild skin irritation.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
NA
NA
3,3',5,5'-Tetramethylbenzidine (TMB) solution >99.0 % NA
NA
No data available.
7722-84-1
MX0887000
Hydrogen peroxide < 1.0 % 231-765-0
008-003-00-9
Ox. Liq. 1: H271
Acute Tox.(O) 4: H302
Skin Corr. 1A: H314
Acute Tox.(I) 4: H332
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Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Air sensitive.
Light sensitive.
Other Precautions:
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Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. NA 3,3',5,5'-Tetramethylbenzidine (TMB)
solution
No data.
TWA: 1.4 mg/m3 (1 ppm)
STEL: 2.8 mg/m3 (2 ppm)
TWA: 1.5 mg/m3 (1 ppm) 7722-84-1 Hydrogen peroxide No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. NA 3,3',5,5'-Tetramethylbenzidine (TMB)
solution
No data.
PEL: 1 ppm TLV: 1 ppm 7722-84-1 Hydrogen peroxide No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
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Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong oxidizing agentsIncompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
nitrogen oxides
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.Information on
Toxicological Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
NA 3,3',5,5'-Tetramethylbenzidine (TMB) solution n.a. n.a. n.a. n.a.
7722-84-1 Hydrogen peroxide n.a. 3 A3 n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
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Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
NA 3,3',5,5'-Tetramethylbenzidine (TMB) solution No No No
7722-84-1 Hydrogen peroxide Yes 1000 LB No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
NA 3,3',5,5'-Tetramethylbenzidine (TMB) solution CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7722-84-1 Hydrogen peroxide CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
Multi-region format
Page 36
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Transcription Factor Stop SolutionSAFETY DATA SHEET
02/28/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100068891.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Stop Solution Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Skin Corrosion/Irritation, Category 1A
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H314: Causes severe skin burns and eye damage.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
DangerGHS Signal Word:
P264: Wash {hands} thoroughly after handling.
P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
GHS Precaution Phrases:
P301+330+331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+361+353: IF ON SKIN (or hair): Remove/take off immediately all contaminated clothing. Rinse skin with
water/shower.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P363: Wash contaminated clothing before reuse.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
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2.3 Causes severe skin burns and eye damage.
Irritating to eyes, respiratory system, and skin.
Chronic exposure to mists containing sulfuric acid is a cancer hazard.
Harmful if swallowed, inhaled, or absorbed through the skin.
Inhalation may cause lung edema.
Long-term exposure to mist or vapors may cause damage to teeth.
Material is irritating to the mucous membranes and upper respiratory tract.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
7664-93-9
WS5600000
Sulfuric acid 0.0 -5.0 % 231-639-5
016-020-00-8
Skin Corr. 1A: H314
7732-18-5
ZC0110000
Water 95.0 -100.0 % 231-791-2
NA
No data available.
4.2
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Circulatory collapse with clammy skin, weak and rapid pulse, shallow respirations, and scanty urine
may follow ingestion or skin contact.
Ingestion may cause: Sore throat, vomiting, and diarrhea.
Irritating to the skin, eyes, nose, throat, and respiratory tract.
Important Symptoms and
Effects, Both Acute and
Delayed:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Do NOT induce vomiting. Wash out mouth with water provided person is conscious. Never give
anything by mouth to an unconscious person. Get medical attention.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, or dry chemical spray.Suitable Extinguishing
Media:
DO NOT USE WATER.Unsuitable Extinguishing
Media:
Concentrated solutions react violently with water, spattering and liberating heat.
Emits toxic and corrosive fumes under fire conditions.
Not Flammable, but reacts with most metals to form flammable hydrogen gas.
Flammable Properties and
Hazards:
5.3
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6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. TWA: 1.0 mg/m3
STEL: 3.0 mg/m3 7664-93-9 Sulfuric acid No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
PEL: 1 mg/m3 TLV: (1 mg/m3)
STEL: (3 mg/m3) 7664-93-9 Sulfuric acid No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
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Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
heatConditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
bases
halogens
hydrides
lithium
metal acetylides
metals
organic material
oxides
potassium chlorate
potassium perchlorate
potassium permanganate
sodium
strong oxidizing agents
strong reducing agents
water
Incompatibility - Materials
To Avoid:
carbon dioxide
hydrogen cyanide
hydrogen sulfide
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
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11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Sulfuric acid - Toxicity Data: Oral LD50 (rat): 2,140 mg/kg; Inhalation TCLO (human): 0.63mg/m3;
Inhalation LC50 (mouse): 320 mg/m3; Inhalation LC50 (guinea pig): 18 mg/m3 (8hr);
Sulfuric acid - Irritation Data: Eyes (rabbit): 5 mg (30s) severe;
Information on
Toxicological Effects:
Sulfuric acid - Investigated as a reproductive effector.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Sulfuric Acid RTECS Number: WS5600000
Chronic Toxicological
Effects:
IARC: 1 - Group 1: Carcinogenic to humans, Occupational exposure to strong-inorganic-acid mists
containing sulfuric acid is carcinogenic to humans.
Carcinogenicity/Other
Information:
IARC ACGIH OSHA
NTP? No IARC Monographs? Yes OSHA Regulated? NoCarcinogenicity:
7664-93-9 Sulfuric acid Known Unknown A2 n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Sulfuric acid [with 51% or less acid]DOT Proper Shipping Name:
8 CORROSIVEDOT Hazard Class:
2796UN/NA Number: IIPacking Group:
14.1 LAND TRANSPORT (US DOT):
Sulfuric acid [with 51% or less acid]ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
2796UN Number: IIPacking Group:
8 - CORROSIVEHazard Class:
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Sulfuric acid [with 51% or less acid]ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
2796UN Number: IIPacking Group:
8 - CORROSIVEHazard Class: 8IATA Classification:
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
7664-93-9 Sulfuric acid Yes 1000 LB Yes 1000 LB Yes
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
7664-93-9 Sulfuric acid CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
Multi-region format
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Transcription Factor Reagent ASAFETY DATA SHEET
06/04/2014Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100074721.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor Reagent A Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
Based on evaluation of currently available data this substance or mixture is not classifiable according to GHS.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
NoneGHS Signal Word:
No phrases apply.
GHS Precaution Phrases:
No phrases apply.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
NA
NA
Transcription Factor Reagent A <=1.0 % NA
NA
No data available.
7732-18-5
ZC0110000
Water >=99.0 % 231-791-2
NA
No data available.
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Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. NA Transcription Factor Reagent A No data.
No data. No data. 7732-18-5 Water No data.
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Transcription Factor Reagent ASAFETY DATA SHEET
06/04/2014Supersedes Revision:
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. NA Transcription Factor Reagent A No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
No data available.Incompatibility - Materials
To Avoid:
No data available.Hazardous
Decomposition or
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
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Byproducts:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.Information on
Toxicological Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
NA Transcription Factor Reagent A n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
NA Transcription Factor Reagent A No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
NA Transcription Factor Reagent A CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
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7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/07/2015Revision Date:
Multi-region format
Page 47
Transcription Factor SREBP 96-Well Strip Plate Item No. 10008858 COMMENTS: Each plate is coated with a dsDNA consensus sequence specific for SREBP. This Safety Data Sheet (SDS) is for the dsDNA only. A SDS on this material is not required as this substance is a naturally occurring animal product. However, we do recommend the following minimum precautions when using this substance:
• Do NOT get in eyes, on skin, or on clothing.
• Do NOT take internally.
• Wear protective gloves and safety glasses.
• Keep container closed.
• Store at correct temperature.
• Do NOT reuse this container.
• Do NOT release this material to the environment; dispose of by incineration in accordance with federal, state, and local regulations.
• Wash thoroughly after handling.
WARNING: Not for human or animal disease diagnostics or therapeutic drug use.
The above information is believed to be correct but should only be used as a guide. Cayman Chemical disclaims any express or implied warranty as to the accuracy of the above information and shall not be held liable for any direct, incidental, or consequential damages resulting from reliance on the above information.
Copyright Cayman Chemical Company Revision Date: 10/23/2012 Supercedes Revision: 03/03/2010
Page 48
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Transcription Factor SREBP Competitor dsDNASAFETY DATA SHEET
10/23/2012Supersedes Revision:
according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100088601.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor SREBP Competitor dsDNA Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
Based on evaluation of currently available data this substance or mixture is not classifiable according to GHS.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
NoneGHS Signal Word:
No phrases apply.
GHS Precaution Phrases:
No phrases apply.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
NA
NA
SREBP Reverse Complement 0.0 -1.0 % NA
NA
No data available.
NA
NA
SREBP Forward Complement 0.0 -1.0 % NA
NA
No data available.
7647-14-5
VZ4725000
Sodium chloride 0.0 -1.0 % 231-598-3
NA
No data available.
6132-04-3
TZ8595800
Sodium citrate 0.0 -1.0 % NA
NA
No data available.
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10/23/2012Supersedes Revision:
7732-18-5
ZC0110000
Water 96.0 -100.0 % 231-791-2
NA
No data available.
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes
examined and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
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Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. NA SREBP Reverse Complement No data.
No data. No data. NA SREBP Forward Complement No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 6132-04-3 Sodium citrate No data.
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. NA SREBP Reverse Complement No data.
No data. No data. NA SREBP Forward Complement No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 6132-04-3 Sodium citrate No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.2
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
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Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
No data available.Incompatibility - Materials
To Avoid:
No data available.Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.Information on
Toxicological Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
NA SREBP Reverse Complement n.a. n.a. n.a. n.a.
NA SREBP Forward Complement n.a. n.a. n.a. n.a.
7647-14-5 Sodium chloride n.a. n.a. n.a. n.a.
6132-04-3 Sodium citrate n.a. n.a. n.a. n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
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13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
NA SREBP Reverse Complement No No No
NA SREBP Forward Complement No No No
7647-14-5 Sodium chloride No No No
6132-04-3 Sodium citrate No No No
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
NA SREBP Reverse Complement CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
NA SREBP Forward Complement CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7647-14-5 Sodium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
6132-04-3 Sodium citrate CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
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Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/09/2015Revision Date:
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according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100108931.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor SREBP-1 Positive Control Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Flammable Liquids, Category 4
Acute Toxicity: Oral, Category 4
Skin Corrosion/Irritation, Category 3
Serious Eye Damage/Eye Irritation, Category 2A
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H227: Combustible liquid.
H302: Harmful if swallowed.
H316: Causes mild skin irritation.
H319: Causes serious eye irritation.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
WarningGHS Signal Word:
P210: Keep away from {heat/sparks/open flames/hot surfaces}. - No smoking.
P264: Wash {hands} thoroughly after handling.
P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
GHS Precaution Phrases:
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy
to do. Continue rinsing.
P330: Rinse mouth.
P332+313: If skin irritation occurs, get medical advice/attention.
P337+313: If eye irritation persists, get medical advice/attention.
GHS Response Phrases:
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Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
2.3 Causes skin and serious eye irritation.
DMSO has the potential to carry toxic materials or materials of unknown toxicity into the body.
DMSO is readily absorbed through skin.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
NA
NA
TF SREBP-1 Positive Control 58.0 -95.0 % NA
NA
No data available.
7365-45-9
TL6809000
HEPES, free acid 0.0 -5.0 % 230-907-9
NA
No data available.
7791-18-6
OM2975000
Magnesium chloride, hexahydrate 0.0 -5.0 % NA
NA
No data available.
68987-90-6
NA
Nonidet P-40 0.0 -1.0 % NA
NA
Skin Corr. 2: H315
Eye Damage 2: H319
STOT (SE) 3: H335
7447-40-7
TS8050000
Potassium chloride 0.0 -5.0 % 231-211-8
NA
Acute Tox.(O) 5: H303
Aquatic (A) 3: H402
56-81-5
MA8050000
Glycerol 5.0 -20.0 % 200-289-5
NA
No data available.
3483-12-3
EK1610000
DL-Dithiothreitol 0.0 -1.0 % 222-468-7
NA
Acute Tox.(O) 4: H302
Skin Corr. 2: H315
Eye Damage 2A: H319
STOT (SE) 3: H335 H336
67-68-5
PV6210000
Dimethyl sulfoxide, anhydrous 0.0 -5.0 % 200-664-3
NA
Flam. Liq. 4: H227
Eye Damage 2A: H319
Skin Corr. 2: H315
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4.2
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Exposure may cause: hematuria or shortness of breath (dyspnea).
Exposure may cause: gastrointestinal irritation with nausea, vomiting, diarrhea, headache,
dizziness, and drowsiness.
Eye contact may cause blurry vision, burning sensation, redness, tearing, and vasodilation.
Important Symptoms and
Effects, Both Acute and
Delayed:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
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Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. NA TF SREBP-1 Positive Control No data.
No data. No data. 7365-45-9 HEPES, free acid No data.
No data. No data. 7791-18-6 Magnesium chloride, hexahydrate No data.
No data. No data. 68987-90-6 Nonidet P-40 No data.
No data. No data. 7447-40-7 Potassium chloride No data.
TWA: 10 mg/m3 ()
STEL: ()
TWA: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 3483-12-3 DL-Dithiothreitol No data.
No data. No data. 67-68-5 Dimethyl sulfoxide, anhydrous No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. NA TF SREBP-1 Positive Control No data.
No data. No data. 7365-45-9 HEPES, free acid No data.
No data. No data. 7791-18-6 Magnesium chloride, hexahydrate No data.
No data. No data. 68987-90-6 Nonidet P-40 No data.
No data. No data. 7447-40-7 Potassium chloride No data.
PEL: 15 (dust); 5 (resp.)
mg/m3
TLV: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 3483-12-3 DL-Dithiothreitol No data.
No data. No data. 67-68-5 Dimethyl sulfoxide, anhydrous No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
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Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.9
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong bases
strong oxidizing agents
Incompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
DMSO - Toxicity Data: Oral LD50 (rat): 14,500 mg/kg; Skin LD50 (rat): 40,000 mg/kg; Oral LD50
(mouse): 7,920 mg/kg; Skin LD50 (mouse): 50,000 mg/kg; Skin TDLO (woman): 1,800 mg/kg;
Inhalation LC50 (rat): >1,600 mg/m3 (4h);
DMSO - Irritation Data: Eyes (rabbit): 100 mg mild; Skin (rabbit): 500 mg (24h) mild;
Glycerol - Irritation Data: Eyes (rabbit): 500 mg (24h) mild; Skin (rabbit): 500 mg (24h) mild;
Information on
Toxicological Effects:
DMSO and Glycerol - Investigated as a mutagen, reproductive effector, and tumorigen.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
DMSO RTECS Number: PV6210000
Glycerol RTECS Number: MA8050000
Chronic Toxicological
Effects:
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
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CAS # Hazardous Components (Chemical Name) NTP IARC ACGIH OSHA
NA TF SREBP-1 Positive Control n.a. n.a. n.a. n.a.
7365-45-9 HEPES, free acid n.a. n.a. n.a. n.a.
7791-18-6 Magnesium chloride, hexahydrate n.a. n.a. n.a. n.a.
68987-90-6 Nonidet P-40 n.a. n.a. n.a. n.a.
7447-40-7 Potassium chloride n.a. n.a. n.a. n.a.
56-81-5 Glycerol n.a. n.a. n.a. n.a.
3483-12-3 DL-Dithiothreitol n.a. n.a. n.a. n.a.
67-68-5 Dimethyl sulfoxide, anhydrous n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
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CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
NA TF SREBP-1 Positive Control No No No
7365-45-9 HEPES, free acid No No No
7791-18-6 Magnesium chloride, hexahydrate No No No
68987-90-6 Nonidet P-40 No No No
7447-40-7 Potassium chloride No No No
56-81-5 Glycerol No No No
3483-12-3 DL-Dithiothreitol No No No
67-68-5 Dimethyl sulfoxide, anhydrous No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
NA TF SREBP-1 Positive Control CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
7365-45-9 HEPES, free acid CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7791-18-6 Magnesium chloride, hexahydrate CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
68987-90-6 Nonidet P-40 CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7447-40-7 Potassium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
56-81-5 Glycerol CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
3483-12-3 DL-Dithiothreitol CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
67-68-5 Dimethyl sulfoxide, anhydrous CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/09/2015Revision Date:
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according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008
100108941.1 Product Code:
Section 1. Identification of the Substance/Mixture and of the Company/Undertaking
Transcription Factor SREBP-1 Primary Antibody Product Name:
Cayman Chemical CompanyCompany Name:1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
CHEMTREC Within USA and Canada:Emergency Contact: +1 (800)424-9300
CHEMTREC Outside USA and Canada: +1 (703)527-3887
Cayman Chemical CompanyInformation: +1 (734)971-3335
For research use only, not for human or veterinary use.Relevant identified uses:
www.caymanchem.comWeb site address:
1.3 Details of the Supplier of the Safety Data Sheet:
1.2 Relevant identified uses of the substance or mixture and uses advised against:
1.4 Emergency telephone number:
Section 2. Hazards Identification
Acute Toxicity: Oral, Category 2
Skin Corrosion/Irritation, Category 3
Aquatic Toxicity (Acute), Category 3
Aquatic Toxicity (Chronic), Category 3
2.1 Classification of the Substance or Mixture:
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:
H300: Fatal if swallowed.
H316: Causes mild skin irritation.
H402: Harmful to aquatic life.
H412: Harmful to aquatic life with long lasting effects.
GHS Hazard Phrases:
2.2 Label Elements:
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
DangerGHS Signal Word:
P264: Wash {hands} thoroughly after handling.
P273: Avoid release to the environment.
GHS Precaution Phrases:
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P330: Rinse mouth.
P332+313: If skin irritation occurs, get medical advice/attention.
GHS Response Phrases:
Please refer to Section 7 for Storage and Section 13 for Disposal information.
GHS Storage and Disposal Phrases:
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2.3 Causes mild skin irritation.
Fatal if swallowed.
Harmful to aquatic life with long lasting effects.
Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation or skin absorption.
May cause eye or respiratory system irritation.
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
Adverse Human Health
Effects and Symptoms:
CAS # /
RTECS #
Hazardous Components (Chemical Name)/
REACH Registration No.
Section 3. Composition/Information on Ingredients
Concentration EC No./
EC Index No.
GHS Classification
NA
NA
TF SREBP-1 Primary Antibody 0.0 -1.0 % NA
NA
No data available.
56-81-5
MA8050000
Glycerol 20.0 -50.0 % 200-289-5
NA
No data available.
9048-46-8
MT6446000
Bovine Serum Albumin (BSA) 0.0 -5.0 % 232-936-2
NA
Acute Tox.(O) 4: H302
7647-14-5
VZ4725000
Sodium chloride 0.0 -5.0 % 231-598-3
NA
No data available.
77-86-1
TY2900000
Trizma base 0.0 -5.0 % 201-064-4
NA
Skin Corr. 2: H315
Eye Damage 2: H319
STOT (SE) 3: H335
26628-22-8
VY8050000
Sodium azide 0.0 -1.0 % 247-852-1
011-004-00-7
Acute Tox.(O) 2: H300
Aquatic (A) 1: H400
Aquatic (C) 1: H410
7732-18-5
ZC0110000
Water 33.0 -80.0 % 231-791-2
NA
No data available.
4.2
Section 4. First Aid MeasuresDescription of First Aid
Measures:
Prolonged exposure may cause nausea, headache, and vomiting.Important Symptoms and
Effects, Both Acute and
Delayed:
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Have eyes examined
and tested by medical personnel.
In Case of Eye Contact:
Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated
clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact:
Wash out mouth with water provided person is conscious. Never give anything by mouth to an
unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by
medical personnel.
In Case of Ingestion:
Remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel.
Get immediate medical attention.
In Case of Inhalation:
4.1
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5.1
5.2
Section 5. Fire Fighting Measures
Flash Pt: No data.
As in any fire, wear self-contained breathing apparatus pressure-demand (NIOSH approved or
equivalent), and full protective gear to prevent contact with skin and eyes.
Fire Fighting Instructions:
Autoignition Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray.
Use water spray to cool fire-exposed containers.
Suitable Extinguishing
Media:
A solid water stream may be inefficient.Unsuitable Extinguishing
Media:
No data available.Flammable Properties and
Hazards:
5.3
6.3
6.1
6.2
Section 6. Accidental Release Measures
Contain spill and collect, as appropriate.
Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For
Containment and Cleaning
Up:
Avoid breathing vapors and provide adequate ventilation.
As conditions warrant, wear a NIOSH approved self-contained breathing apparatus, or respirator,
and appropriate personal protection (rubber boots, safety goggles, and heavy rubber gloves).
Protective Precautions,
Protective Equipment and
Emergency Procedures:
Take steps to avoid release into the environment, if safe to do so.Environmental
Precautions:
7.1
7.2
Section 7. Handling and StorageAvoid breathing dust/fume/gas/mist/vapours/spray.
Avoid prolonged or repeated exposure.
Precautions To Be Taken
in Handling:
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Precautions To Be Taken
in Storing:
Section 8. Exposure Controls/Personal Protection
Britain EH40 France VLCAS # Partial Chemical Name Europe
8.1 Exposure Parameters:
No data. No data. NA TF SREBP-1 Primary Antibody No data.
TWA: 10 mg/m3 ()
STEL: ()
TWA: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 77-86-1 Trizma base No data.
TWA: 0.1 mg/m3 ()
STEL: 0.3 mg/m3 ()
TWA: 0.1 mg/m3
STEL: 0.3 mg/m3 26628-22-8 Sodium azide TWA: 0.1 mg/m3
STEL: 0.3 mg/m3
No data. No data. 7732-18-5 Water No data.
OSHA TWA ACGIH TWACAS # Partial Chemical Name Other Limits
No data. No data. NA TF SREBP-1 Primary Antibody No data.
PEL: 15 (dust); 5 (resp.)
mg/m3
TLV: 10 mg/m3 56-81-5 Glycerol No data.
No data. No data. 9048-46-8 Bovine Serum Albumin (BSA) No data.
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No data. No data. 7647-14-5 Sodium chloride No data.
No data. No data. 77-86-1 Trizma base No data.
No data. CEIL: 0.29 mg/m3 26628-22-8 Sodium azide No data.
No data. No data. 7732-18-5 Water No data.
8.2.1
NIOSH approved respirator, as conditions warrant.Respiratory Equipment
(Specify Type):
Safety glassesEye Protection:
Compatible chemical-resistant glovesProtective Gloves:
Lab coatOther Protective Clothing:
Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Engineering Controls
(Ventilation etc.):
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety
shower.
Wash thoroughly after handling.
Work/Hygienic/Maintenan
ce Practices:
No data available.
8.2 Exposure Controls:
8.2.2 Personal protection equipment:
Section 9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Vapor Pressure (vs. Air or mm
Hg):
No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate: No data.
pH: 7.4
SolutionAppearance and Odor:
9.1 Information on Basic Physical and Chemical Properties
Flammability (solid, gas): No data available.
Specific Gravity (Water = 1): No data.
Solubility in Water: No data.
Autoignition Pt: No data.
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Percent Volatile: No data.
9.2 Other Information
10.4
10.5
10.6
10.1
10.2
10.3
Section 10. Stability and Reactivity
No data available.Conditions To Avoid:
Unstable [ ] Stable [ X ]Stability:
strong bases
strong oxidizing agents
Incompatibility - Materials
To Avoid:
carbon dioxide
carbon monoxide
Hazardous
Decomposition or
Byproducts:
Will occur [ ] Will not occur [ X ]Polymerization:
Stable if stored in accordance with information listed on the product insert.Stability Note(s):
No data available.Reactivity:
11.1
CAS # Hazardous Components (Chemical Name) NTP
Section 11. Toxicological InformationThe toxicological effects of this product have not been thoroughly studied.
Glycerol - Irritation Data: Eyes (rabbit): 500 mg (24h) mild; Skin (rabbit): 500 mg (24h) mild;
Information on
Toxicological Effects:
Glycerol - Investigated as a mutagen, reproductive effector, and tumorigen.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Glycerol RTECS Number: MA8050000
Chronic Toxicological
Effects:
IARC ACGIH OSHA
NTP? No IARC Monographs? No OSHA Regulated? NoCarcinogenicity:
NA TF SREBP-1 Primary Antibody n.a. n.a. n.a. n.a.
56-81-5 Glycerol n.a. n.a. n.a. n.a.
9048-46-8 Bovine Serum Albumin (BSA) n.a. n.a. n.a. n.a.
7647-14-5 Sodium chloride n.a. n.a. n.a. n.a.
77-86-1 Trizma base n.a. n.a. n.a. n.a.
26628-22-8 Sodium azide n.a. n.a. A4 n.a.
7732-18-5 Water n.a. n.a. n.a. n.a.
12.1
12.2
12.3
12.4
12.5
Avoid release into the environment.
Runoff from fire control or dilution water may cause pollution.
Toxicity:
Section 12. Ecological Information
No data available.Persistence and
Degradability:
No data available.Bioaccumulative
Potential:
No data available.Mobility in Soil:
No data available.Results of PBT and vPvB
assessment:
12.6 No data available.Other adverse effects:
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13.1 Dispose in accordance with local, state, and federal regulations.Waste Disposal Method:
Section 13. Disposal Considerations
Section 14. Transport Information
Not dangerous goods.DOT Proper Shipping Name:
DOT Hazard Class:
UN/NA Number:
14.1 LAND TRANSPORT (US DOT):
Not dangerous goods.ADR/RID Shipping Name:
14.1 LAND TRANSPORT (European ADR/RID):
UN Number:
Hazard Class:
Not dangerous goods.ICAO/IATA Shipping Name:
14.3 AIR TRANSPORT (ICAO/IATA):
Transport in accordance with local, state, and federal regulations.Additional Transport
Information:
CAS # Hazardous Components (Chemical Name)
Section 15. Regulatory Information
S. 302 (EHS) S. 304 RQ S. 313 (TRI)
EPA SARA (Superfund Amendments and Reauthorization Act of 1986) Lists
NA TF SREBP-1 Primary Antibody No No No
56-81-5 Glycerol No No No
9048-46-8 Bovine Serum Albumin (BSA) No No No
7647-14-5 Sodium chloride No No No
77-86-1 Trizma base No No Yes-Cat. N106
26628-22-8 Sodium azide Yes 500 LB Yes 1000 LB Yes
7732-18-5 Water No No No
CAS # Hazardous Components (Chemical Name) Other US EPA or State Lists
NA TF SREBP-1 Primary Antibody CAA HAP,ODC: No; CWA NPDES: No; TSCA: No; CA
PROP.65: No
56-81-5 Glycerol CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
9048-46-8 Bovine Serum Albumin (BSA) CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7647-14-5 Sodium chloride CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
77-86-1 Trizma base CAA HAP,ODC: HAP; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
26628-22-8 Sodium azide CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
7732-18-5 Water CAA HAP,ODC: No; CWA NPDES: No; TSCA: Yes -
Inventory; CA PROP.65: No
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This SDS was prepared in accordance with 29 CFR 1910.1200 and Regulation (EC)
No.1272/2008.
Regulatory Information
Statement:
Section 16. Other Information
No data available.Additional Information About
This Product:
DISCLAIMER: This information is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability resulting from its
use. Users should make their own investigations to determine the suitability of the information for
their particular purposes.
Company Policy or Disclaimer:
05/09/2015Revision Date:
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