Select Risk Factors and Outcomes Related to Chronic Diseases Presented to 10/14/2011 The Cancer, Cardiovascular and Pulmonary Disease Grants Committee
Oct 22, 2014
Select Risk Factors and
Outcomes Related to Chronic
Diseases
Presented to
10/14/2011 The Cancer, Cardiovascular and Pulmonary Disease Grants
Committee
Acknowledgements Renee Calanan, PhD
Chronic Disease Epidemiologist, PHS
&
Stephanie Kuhn
Barbara Gabella
Indira Gujral
Ashley Juhl
Biology 20%
Health Care 10%
Environment 19%
Lifestyle 51%
Smoking Obesity Nutrtion
Alcohol Use
Source: McGinnis, J.M and Foege, W.H. (1993). ―Actual Causes of Death
in the United States,‖ Journal of the American Medical Association.
Factors Influencing Health Status
Determinants of Health (Evans - Stoddart Model)
Social Physical Genetic
Environment Environment Environment
Individual
Response
– Behavior
– Biology
Health Disease Health &
& & Medical
Function Injury Care
Well – Being Prosperity
Paul Simon, MD, MPH, UCLA, 2007
Mortality
Number of deaths for the fifteen leading
causes of death — Colorado residents, 2010
549
598
721
867
1336
1605
2102
2199
6029
7029
0 1000 2000 3000 4000 5000 6000 7000 8000
Influenza and Pneumonia
Chronic Liver Disease and Cirrhosis
Diabetes Melitus
Suicide
Alzheimer's Disease
Cerebrovascular Disease
Unintentional injuries
Chronic Lower Respiratory Disease
Heart Disease
Cancer (Malignant neoplasms)
Cau
se o
f d
eath
Number of deaths Source: CDPHE, Health Statistics Section. Vital Records. Death statistics obtain via CoHID Oct 10, 2011
Percent of total deaths for the leading
causes of death — Colorado residents, 2008
1.7% 1.9%
2.3%
2.8%
4.3%
5.1%
6.7%
7.0%
19.2%
22.4%
26.7%
Influenza and Pneumonia
Chronic Liver Disease and Cirrhosis
Diabetes Melitus
Suicide
Alzheimer's Disease
Cerebrovascular Disease
Unintentional injuries
Chronic Lower Respiratory Disease
Heart Disease
Cancer (Malignant neoplasms)
All other causes
Source: CDPHE, Health Statistics Section. Vital Records. Death statistics obtain via CoHID Oct 10, 2011
Outcomes Among
Adults
How many people are affected?
• 751,000 had hypertension(22%)
• 307,000 had current asthma (8%)
• 190,000 were cancer survivors (4%)
• 113,000 had coronary artery disease (3%)
• 219,000 had diabetes (6%)
• 70,000 had a stroke (2%)
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Select outcomes by race/ethnicity and
income, Colorado adults, 2009
Outcome Race/ethnicity Income
Asthma No disparity No disparity
Coronary artery disease No disparity Most lower incomes > $75k+
Hypertension Black>White>Hispanic Lower incomes > $75+
Diabetes Black, Hispanic > White Most lower incomes > $75k+
Cancer Not assessed Not assessed
Risk Factors Among
Adults
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
0
5
10
15
20
25
30
35
40
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
Prevalence of selected risk factors, Colorado adults, 1997-2010 BRFSS
Overweight High cholesterol Current smokers Hypertension Physical inactivity Obesity
22.8 22.3
19.8
17.1 16
5
10
15
20
25
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
Perc
en
t
Percent of Colorado adult smokers, 1996-2009
Healthy People 2020 Objective: 12%
Source: Colorado Behavioral Risk Factor Surveillance System, Health Statistics Section,
Colorado Department of Public Health and Environment
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
0
5
10
15
20
25
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
Prevalence of obesity among adult Coloradans, 1997-2010 BRFSS
Obesity
Healthy People 2020 Objective: 30%
25 22
35
19
57
18 17
0
10
20
30
40
50
60
70
80
90
100
Fruit/vegetables 5+ times per day
High blood pressure
High cholesterol Obesity Meet physical activity recs
Physically inactive
Current smoker
Prevalence of select risk factors,
Colorado adults, 2009 (in pct.)
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
High blood pressure by race/ethnicity
and income, Colorado adults, 2009
29 28 25 25
21 18
0
5
10
15
20
25
30
35
40
45
50
23
34
18
0
5
10
15
20
25
30
35
40
45
50
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
High cholesterol by race/ethnicity and
income, Colorado adults, 2009
35 34 36
0
5
10
15
20
25
30
35
40
45
50
White non-Hispanic Black non-Hispanic Hispanic
37
41
36 37 35
33
0
5
10
15
20
25
30
35
40
45
50
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Obesity by race/ethnicity and income,
Colorado adults, 2009
26 23 22
19 20
17
0
5
10
15
20
25
30
35
40
45
50
18
31
22
0
5
10
15
20
25
30
35
40
45
50
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Physical activity by race/ethnicity and
income, Colorado adults, 2009
51 50 55 55 58
63
0
10
20
30
40
50
60
70
80
90
100
59 56
51
0
10
20
30
40
50
60
70
80
90
100
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Physical inactivity by race/ethnicity and
income, Colorado adults, 2009
33
28
23
20
14
9
0
5
10
15
20
25
30
35
40
45
50
14
29 28
0
5
10
15
20
25
30
35
40
45
50
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Current smoking by race/ethnicity and
income, Colorado adults, 2009
16
20 20
0
5
10
15
20
25
30
35
40
45
50
White non-Hispanic Black non-Hispanic Hispanic
27 28 28
18 17
9
0
5
10
15
20
25
30
35
40
45
50
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Screening Among Adults
Prevalence of preventive screening,
Colorado adults, 2008
76
62
84
76 73
0
10
20
30
40
50
60
70
80
90
100
Cholesterol within 5 years (18+ years)
Colorectal cancer (50+ years) Cervical cancer within 3 years (18+ years)
Breast cancer within 2 years (50+ years)
Breast cancer within 2 years (40+ years)
Colorectal cancer: colonoscopy within 10 years, sigmoidoscopy within 5 years, or FOBT within 1 year
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment (cholesterol screening, 2009)
Cholesterol screening by
race/ethnicity and income,
Colorado adults, 2009
79 78
61
0
10
20
30
40
50
60
70
80
90
100
White non-Hispanic Black non-Hispanic Hispanic
68 62
70
77 78
86
0
10
20
30
40
50
60
70
80
90
100
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Colorectal cancer screening by
race/ethnicity and income, Colorado
adults aged 50+ years, 2008
47
56 59
64 64 68
0
10
20
30
40
50
60
70
80
90
100
64
72
54
0
10
20
30
40
50
60
70
80
90
100
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Cervical cancer screening by
race/ethnicity and income, Colorado
women aged 18+ years, 2008
71
79 80 84
89 93
0
10
20
30
40
50
60
70
80
90
100
86 87 81
0
10
20
30
40
50
60
70
80
90
100
White non-Hispanic Black non-Hispanic Hispanic
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Breast cancer screening by
race/ethnicity and income, Colorado
women aged 50+ years, 2008
77 76
0
10
20
30
40
50
60
70
80
90
100
White non-Hispanic Black non-Hispanic Hispanic
61
70 72 78
80 82
0
10
20
30
40
50
60
70
80
90
100
Data source: Behavioral Risk Factor Surveillance System, Health Statistics Section, Colorado Department of Public Health and Environment
Disparities in Screening
• Hispanics had a lower prevalence of
cholesterol screening and colorectal
cancer screening than Whites and Blacks.
• In general, screening increased as annual
household income increased.
Risk Factors Among
Youth
78
27 24
12
0
10
20
30
40
50
60
70
80
90
100
Healthy weight Recommended physical activity Fruit/vegetables 5+ times/day Current smoker
Select risk factors and outcomes,
Colorado adolescents, 2009
Current smoking data source: Healthy Kids Colorado Survey on Tobacco and Health, Colorado Department of Public Health and Environment, analyzed by Amendment 35 Program Evaluation Group (APEG), University of Colorado Cancer Center
Data source: Colorado Youth Risk Behavior Survey, Colorado Department of Education; analyzed by Colorado Department of Public Health and Environment
Select risk factors and outcomes,
Colorado children, 2009
65
10
31
48
16
45
9
0
10
20
30
40
50
60
70
80
90
100
Healthy weight (5-14y)
Eat fruit 2+ times and vegetables 3+ times
per day (2-14y)
Drink sweetened drinks 1+ times per
day (1-14y)
Active everyday for 60+ minutes (5-14y)
Watch TV >2 hours per day (1-14y)
Sunburn in past 12 months (1-14y)
Current asthma (1-14y)
Data source: Colorado Child Health Survey, Colorado Department of Public Health and Environment
Risk Factors’
Associations with
Outcomes
34
COPD • 90% of Chronic Obstructive Pulmonary Disease
Diabetes •Leads to neuropathy & peripheral artery disease •Smoking increases the risk of amputation by 2 – 10 times
Cancers • 80-90% of lung • 30-50% of colon • 75% of oral (w/ alcohol) • Cancers of the bladder cervix, esophagus, larynx, kidney & pancreas
Reducing Cigarette Smoking
CVD • 2-4 x risk of coronary heart disease • 2 x risk of sudden cardiac death • Abdominal aortic aneurysm • Strokes • Atherosclerosis & congestive heart failure
35
Type 2 Diabetes • End stage renal • 65% of people with diabetes die from heart disease or stroke
CVD • 30-40% of coronary heart disease
• 10-20% of stroke
Lowering cholesterol & hypertension
CVD • 20-30% of coronary heart disease • 20-50% of stroke
36
Type 2 Diabetes
CVD • heart disease by 20-40% • stroke by 30%
Diabetes • 12% of diabetes
CVD • 12% of hypertension
Cancers • 30% of cancer deaths • Nutrition: Cancers of the mouth, pharynx, esophagus, larynx, kidney, colon, rectum, ovary, & bladder
Nutrition & Physical Activity
Cancer • 22% of colon cancers • Cancers of breast, colon, and possibly endometrial & prostate
37
Cancers • Cancers of the colon, breast, kidney, gallbladder, prostate, cervix, ovaries, & esophagus
50-100% greater risk of premature death
Diabetes • Increased risk of Type 2 Diabetes
Reducing Obesity
CVD • Increased likelihood of heart disease and stroke
Thank you
Gabriel Kaplan, PhD., MPA, Director
EPE | Epidemiology, Planning and Evaluation | Branch
Prevention Services Division
Colorado Department of Public Health and Environment