cording and Analyzing EEG in Ambulato n Davis 1 , Beverly Sturges 2 , Charles H. Vit 5 , Andrew B. Gardner 6 , Ann Chamberlain Litt 1,7 Penn Epilepsy Center, Dept. of Neuro School of Veterinary Medicine, Unive School of Veterinary Medicine, Unive NeuroVista Corporation NeuroVista Corporation Mayo Clinic, Rochester MN Momentics Corporation Dept. of Bioengineering, University Brian L Associate Profess Associate Professor g Continuous Intracra ory Epileptic Dogs te 3 , Vanessa Ruedebusch 4 , Gregory n 7 , Kent Leyde 4 , W. Douglas Sheffield 4 , ology, University of Pennsylvania ersity of California Davis ersity of Pennsylvania of Pennsylvania Litt, MD sor of Neurology r of Bioengineering
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Recording and Analyzing Continuous IntracranialEEG in Ambulatory Epileptic Dogs
Kathryn Davis1, Beverly Sturges2, Charles H. Vite5, Andrew B. Gardner6, Ann Chamberlain
Brian Litt 1,7
Penn Epilepsy Center, Dept. of Neurology, University of PennsylvaniaSchool of Veterinary Medicine, University of California DavisSchool of Veterinary Medicine, University of PennsylvaniaNeuroVista CorporationNeuroVista CorporationMayo Clinic, Rochester MNMomentics CorporationDept. of Bioengineering, University of Pennsylvania
Brian Litt, MDAssociate Professor of Neurology
Associate Professor of Bioengineering
Recording and Analyzing Continuous IntracranialEEG in Ambulatory Epileptic Dogs
, Charles H. Vite3, Vanessa Ruedebusch4, Gregory, Ann Chamberlain7, Kent Leyde4, W. Douglas Sheffield4,
Penn Epilepsy Center, Dept. of Neurology, University of PennsylvaniaSchool of Veterinary Medicine, University of California DavisSchool of Veterinary Medicine, University of Pennsylvania
Dept. of Bioengineering, University of Pennsylvania
Brian Litt, MDAssociate Professor of Neurology
Associate Professor of Bioengineering
The NeuroVista System
• 6 dogs• 6 dogs• Natural epilepsy• Automated alert• > 1 year• Sz detect/ predict• ? Treatment
The NeuroVista System
ImplantationImplantation
Normal SleepNormal Sleep
Normal AwakeNormal Awake
Focal IEDsFocal IEDs
Focal Subclinical SeizureFocal Subclinical Seizure
Focal and Diffuse Sz Onsetsuse Sz Onsets
Sz Susceptibility & Treatment
Seizures
Susceptibilityparameter
Sz Susceptibility & Treatment
Pb administered
Support
NeuroVistaNINDS (R01NS04181104, RO1The Dr. Michel and Mrs. Anna Mirowski Discovery Fund
Support
04, RO1NS4859801)The Dr. Michel and Mrs. Anna Mirowski Discovery Fund
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