Blending in Functional MRI Wim Corbijn van Willenswaard Chair WG16 (MRI)
Jan 05, 2016
Blending in Functional MRI
Wim Corbijn van Willenswaard
Chair WG16 (MRI)
Agenda
Functional MRI
Objects involved
How to combine the objects
September 2015, FMRI F2F and WG06 Functional MRI data mapping 2
Functional MRI
Combining:• Anatomical data • Functional data• Registration (optional) to align data
Combined by:• Blending operation
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Anatomical data
Standard gray scale data (can be color)
Used to locate the area of the Functional activity
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Functional data
Parametric data describing relation between an voxel and the Functional activity
Can be:• Statistical parameter• Functional activation• Cardiovascular reactivity• Functional connectivity• Other
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Registration
Registration would be needed for
• Data having different Frame of Reference• Compensate for movements during the Assessment• Compensate for Image distortion
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Result
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View combining:- Anatomical image- 4 parametric maps
Using:• Thresholds• Opacity
Result
September 2015, FMRI F2F and WG06 Functional MRI data mapping 8
Result
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Objects involved
Anatomical data:• Enhanced MR Image object (or other modality)
Functional data:• Parametric Map object
Registration data:• (Deformable) Spatial registration object
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Parametric map
Functional information Color
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FunctionalFloating pointinformation
Integer map Color map
Real world value mapping
Color LUT
Not present
Remark: Color LUT is present for integer map, but not for floating point
Combining Objects
Blending Presentation State• Combines two gray scale objects• Adds color to the object used for overlay• Defines opacity
• Not able to use the Parametric map• Not able to combine more than two objects
September 2015, FMRI F2F and WG06 Functional MRI data mapping 12
How to continue
New Blending object:- Combining more than 2 objects- 2D Datasets (anatomical and parametric):
- Equal #slices- Equal geometry- NO Registration
- Allow coloring + opacity for every layer- Handles Threshold of parametric map- Enable Threshold contour display
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Parametric Map
Extensions needed:- Threshold information- Double / Floating point map Scalar for
coloring (Identity Pixel Value Transformation?)
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Not Covering
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Questions
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Questions
• Different number of frames• MPR / Geometry difference• Registration might need “MPR”• Threshold and Value representation / CP?• Leave out Tract set for now.• Anatomical can be a set of Classic Images• Can registration be used for parametric map• How to translate Floats to Colors• How to convey the meaning of a parametric Map RW value
reference or enhance the Parametric map• Store image pixel, in combination with RW value IOD/macro• Can we enhance the Alpha LUT transfer function to cope with
Threshold.
September 2015, FMRI F2F and WG06 Functional MRI data mapping 17
Result
Combined:• Anatomical grayscale image• Parametric map
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Combining Objects
Option 2: (Planar MPR) Volumetric Presentation State• Combines multiple Volumetric objects• Extensive color capabilities for objects• Defines opacity
• Defines lot more than needed
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