BIOLOGI MOLEKULER-MASHURI MASRI,S.Si., M.Kes.pdf

8/18/2019 BIOLOGI MOLEKULER-MASHURI MASRI,S.Si., M.Kes.pdf

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BIOLOGI

MOLEKULER DNA

Dedicated By

Mashuri Masri, S.Si., M.Kes

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TUJUAN PEMBELAJARAN

1.Defenisi Biologi Molekuler

2. Inti Sel, Kromosom, DNA, Basa Nitrogen, Gen.

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Inti SelKROMOSOM

DNABASA

NIROGEN

AGCT

GEN

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Struktur DNA

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Kariotipe Pria

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Kariotipe Perempuan

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Karioptipe Pria Karioptipe Perempuan

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Kromosom♂

Kromosom Tubuh

22 pasang44 buah

Kromosom Seksual

1 pasang

2 buah(XY)

46

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Kromosom

♀

Kromosom Tubuh

22 pasang44 buah

Kromosom Seksual

1 pasang

2 buah(XX)

46

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• Three representations of DNA

Figure 10.3D

Ribbon model Partial chemical structure Computer model

Hydrogen bond

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inti selkromosom

DNA Gula

Pentosa

Asam

Posfat

Basa

Nitrogen

GEN

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Aturan dasar

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Bagaimana dengan virus genomRNA ??

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• A specific gene specifies a polypeptide

– The DNA is transcribed into RNA, which is

translated into the polypeptide

Figure 10.6A

DNA

RNA

Protein

TRANSCRIPTION

TRANSLATION

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Figure 10.7

DNA molecule

Gene 1

Gene 2

Gene 3

DNA strand

TRANSCRIPTION

RNA

Polypeptide

TRANSLATION

Codon

Amino acid

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Huruf kedua


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U C A G

Hu

ruf

Per

ta

ma

U

UUU

Fenilalanin

UUC

Fenilalanin

UUA LeusinUUG Leusin

UCU Serin

UCC Serin

UCA Serin

UCG Serin

UAU Tirosin

UAC Tirosin

UAA stop

UAG stop

UGU Sistein

UGC Sistein

UGA stop

UGG Triptofan

U

C

A

G

Hu-

ruf

Ke

Tig

a

C

CUU Leusin

CUC Leusin

CUA Leusin

CUG Leusin

CCU Prolin

CCC Prolin

CCA Prolin

CCG Prolin

CAU Histidin

CAC Histidin

CAA Glutamin

CAG Glutamin

CGU Arginin

CGC Arginin

CGA Arginin

CGG Arginin

U

C

A

G

A

AUU Isoleusin

AUCIsoleusin

AUA Isoleusin

AUG Metionin

ACU Treonin

ACC Treonin

ACA Treonin

ACG Treonin

AAU Asparagin

AAC Asparagin

AAA Lisin

AAG Lisin

AGU Serin

AGC Serin

AGA Argini n

AGG Arginin

U

C

A

G

G

GUU Valin

GUC Valin

GUA Valin

GUG Valin

GCU Alanin

GCC Alanin

GCA Alanin

GCG Alanin

GAU AsamAspartat

GAC AsamAspartat

GAA AsamGlutamat

GAG AsamGlutamat

GGU Glisin

GGC Glisin

GGA Glisin

GGG Glisin

U

C

A

G


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REFERENSI

• Triwibowo Yuwono (2005). PCR.

Yogyakarta, Penerbit Erlangga.

• Fatchiyah, Estri L.A., Sri W., Sri

R.,(2011). Biologi Molekuler, Prinsip Dasar

Analisis. Jakarta,Penerbit

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BIOLOGI MOLEKULER-MASHURI MASRI,S.Si., M.Kes.pdf

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