HIGH SURVIVABILITY: Can withstand the harsh environment of stomach acid (low pH) and bile juices to reach the intestine where it colonizes HIGHLY RESILIENT: Can survive the shipping, manufacturing, and transport processes without loss of any viability SUPERIOR VIABILITY: Stable at room temperature, requires no refrigeration. RESISTANT TO A GREATER RANGE OF TEMPERATURES: Can survive a range of temperatures - high boiling to low freezing temperatures. This has a wide application in the food industry as it can be incorporated into a broad range of foods NEEDS NO MICRO ENCAPSULATION: Makes it a cost effective probiotic which can be incorporated into a wide range of foods • Aids in digestion • Helps maintain the intestinal flora • Helps support a healthy immune system Why We Recommend Applications Bacillus coagulans Unique IS2 is an ideal ingredi- ent which can be added to foods, beverages and supplements to fortify them as it is stable across all temperatures. Some examples include Baked foods - cakes , muffins and cookies Dry powders - cake and soup mixes Finished products -granola, protein bars and breakfast cereals Dairy products -cheese, milk products, ice creams and yoghurts Beverages - coffee, tea and juices Candies and gummies. Food Applications www.uniquebiotech.com Bacillus coagulans Bacillus coagulans Unique IS2 is a gram positive, spore forming bacterium. It is non-pathogenic and safe for human consumption. Being naturally encapsulated, it is a robust and stable probiotic making it the probiotic of choice in the food and pharmaceutical industry. Bulk powder 6/15/25/50/100/150/200/250 billion cfu/g and enteric coated pellets Finished formulations - Capsules, Sachets & Chewable Tablets Fiber board drums with double polythene liners Store in a cool and dry place. Availability, Packing & Storage • Stable for 3 years Stability Supporting Documentation • Certificate of Analysis (COA) • Material Safety Data Sheet (MSDS) • GMO Free Certificate • BSE/TSE Free Declarations • Stability Data • Dossier • Halal and Kosher Certification • WHO GMP, ISO 9001:2008
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HIGH SURVIVABILITY: Can withstand the harsh environment of stomach acid (low pH) and bile juices to reach the intestine where it colonizes
HIGHLY RESILIENT: Can survive the shipping, manufacturing, and transport processes without loss of any viability
SUPERIOR VIABILITY: Stable at room temperature, requires no refrigeration.
RESISTANT TO A GREATER RANGE OF TEMPERATURES: Can survive a range of temperatures - high boiling to low freezing temperatures. This has a wide application in the food industry as it can be incorporated into a broad range of foods
NEEDS NO MICRO ENCAPSULATION: Makes it a cost effective probiotic which can be incorporated into a wide range of foods
• Aids in digestion• Helps maintain the intestinal flora• Helps support a healthy immune system
Why We Recommend Applications
Bacillus coagulans Unique IS2 is an ideal ingredi-ent which can be added to foods, beverages and supplements to fortify them as it is stable across all temperatures. Some examples includeBaked foods - cakes , muffins and cookiesDry powders - cake and soup mixesFinished products -granola, protein bars and breakfast cereals Dairy products -cheese, milk products, ice creams and yoghurtsBeverages - coffee, tea and juicesCandies and gummies.
Food Applications
www.uniquebiotech.com
Bacillus coagulans
Bacillus coagulans Unique IS2 is a gram positive, spore forming bacterium. It is non-pathogenic and safe for human consumption. Being naturally encapsulated, it is a robust and stable probiotic making it the probiotic of choice in the food and pharmaceutical industry.
Bulk powder 6/15/25/50/100/150/200/250 billion cfu/g and enteric coated pelletsFinished formulations - Capsules, Sachets & Chewable Tablets Fiber board drums with double polythene linersStore in a cool and dry place.
Availability, Packing & Storage
• Stable for 3 years
Stability
Supporting Documentation
• Certificate of Analysis (COA)• Material Safety Data Sheet (MSDS)• GMO Free Certificate• BSE/TSE Free Declarations• Stability Data • Dossier• Halal and Kosher Certification• WHO GMP, ISO 9001:2008
www.uniquebiotech.com
References1. Ratna Sudha et al., (2010). Molecular typing and probiotic attributes of a new strain of Bacillus coagulans Unique IS-2 potential therapeutic agent ; Genetic Engineering and Biology journal. GEBJ-72. Ratna Sudha et al., (2011). Safety study of Bacillus coagulans Unique IS-2 in rats: morphological, biochemical and clinical evaluation; Interna-tional Journal of Probiotics and Prebiotics, 6,(1):43-483. Ratna Sudha et al., (2011). Clinical study of Bacillus coagulans Unique IS-2 in treatment of patients with bacterial vaginosis ; Indian Journal of Microbiology.52(3): 396-3994. Ratna Sudha et al., (2011). Effect of supplementation of Bacillus coagulans Unique IS-2(ATCC pat-11748) on hypercholesterolemic subjects: a clinical study; International Journal of Probiotics and Prebiotics, 6,(2):89-945. Sudha, Ratna M.; Bhonagiri, Shivaram (2012) Efficacy of bacillus coagulans strain Unique IS-2 in the treatment of patients with acute diarrhea; International Journal of Probiotics and Prebiotics: 7(1): 33
Specification For Bacillus coagulans
S.No
1.
2.
3.
4.
5.
6.
7.
8.
9.
Test
Description
Identification
Lactic Acid Producing Capacity
Loss on drying
Standard concentration
Pathogens
Yeast & Mold count
Other Organisms
Heavy metals:LeadCadmiumMercuryArsenic
Specifications
Free flowing white to grayish white to brown color powder with characteristic odour , slightly sweet in taste.
The spores are seen as small terminal oval shaped refractile bodies at the end of each vegetative cell.
Not less than 14 ml of 0.05 N Sodium hydroxide should be consumed
Not more than 5.0%
15/25/50/100/200 Billion cfu/g Should be absent
Not more than 100 cfu/g
Not more than 0.15 /0.25/0.5/1.0 / 2.0 million cfu/g Not more than 2 ppm Not more than 1 ppmNot more than 0.1 ppmNot more than 1 ppm
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