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ASSESSMENT OF
AV FISTULA
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AV access types
Fistula:
Formed by subcutaneous anastomosis of an
artery to an adjacent vein, allowing flow directlyfrom artery to vein.
Graft :
a tube made of prosthetic material bridges thegap between the feeding artery and vein
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AV fistula over Grafts : Why?
Lesser stenosis rates.
Lesser infection rates.
Simple surgical procedure, done on OPD
basis.
Thus avoiding/ markedly reducing
hospitalization and emergency
operations for complications
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Comparison of graft and fistula
outcomes in HD patients
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Comparison of graft and fistula
outcomes in HD patients
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GUIDELINES
KDOQI, & Fistula First initiative: Targeting
60 % use of AV fistulas in patients
beginning on HD, and 50 % fistula use inprevalent patients.
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HURDLES: Fistula Hurdle
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Hurdles OVERCOME by:
Early referral to nephrologist
Early access evaluation and construction of
access avoid central vein cannulation. Use of preop imaging of arterial & venous
system to maximize successful creation of
functioning fistula
Dedicated and trained vascular surgeon as part
of vascular access team.
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ANTICIPATE NEED FOR AV
access. In pts with progressive renal failure protect the veins
minimize venipunctures and catheter placement inforearm veins.
Avoid subclavian vein catherterization.
Avoid PICC.
Create AVF atleast 6 months prior to initiating HD.
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EVALUATION
Preop evaluation
For Maturation
For complication
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EVALUATION
PREOP Evaluation:
history
physical examination
imaging studies.
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Pt HISTORY
Dominant arm: To minimize negative
impact on quality of life, use of the
nondominant arm is preferred. History of previous central venous
catheter, History of pacemaker use :
associated with central venous stenosis
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Pt HISTORY
History of severe congestive heart failure:Accesses may alter hemodynamics and cardiacoutput.
History of arterial or venous peripheral catheter:Previous placement of an arterial or venousperipheral catheter may have damaged targetvasculature
History of diabetes mellitus: Diabetes mellitus isassociated with damage to vasculaturenecessary for internal accesses.
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Pt HISTORY
History of anticoagulant therapy or any coagulationdisorder: Abnormal coagulation may cause clotting orproblems with hemostasis of accesses.
Presence of comorbid conditions, such as malignancy orcoronary artery disease, that limit patients lifeexpectancy. Morbidity associated with placement andmaintenance of certain accesses may not justify theiruse in some patients.
History of vascular access: Previously failed vascularaccesses will limit available sites for accesses.
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EXAMINATION
Bp, arm girth, Allens test in both arms.
Arm edema, presence of collterals,
differential exterimity size central veinstenosis.
Look for evidence of central or venous
catheterization, trauma to arm, chest neck.
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Imaging studies
Routinely used
To select appropriate vessel and location
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Imaging studies
Doppler ultrasonography
Venography
Arteriography
Magnetic resonance
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DOPPLER ULTRASONOGRAPHY
To check arterial inflow.
To assess venous anatomy and patency prior to
AV fistula formation or graft insertion. To identify the presence of cephalic vein
branches needing ligation to prevent diversion of
flow from the fistula.
To study subclavian vein patency as stenosis
there leads to early failure of the fistula
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DOPPLER ULTRASONOGRAPHY
SIZE: lumen diameter:
feeding artery 2 mm
target vein 2.5 mm
NORMAL VEIN : lumen is echo free.
thin wall. Wall thickeningpathology.
valves may be seen
comprssible with min externalpressure.
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DOPPLER ULTRASONOGRAPHY
VEIN DILATION TEST: 50% increase in
internal diameter of vein after proximal
occlusion is associated with a good fistulaoutcome.
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DOPPLER ULTRASONOGRAPHY
ARTERIAL DILATION
TEST: Pulse contour of
artery is normally
triphasic.
Clench fist for 2 mins and
then open it during
hyperemic phase the
pulse contour will bebiphasic - adequate
arterial dilatation.
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VENOGRAHY: Indications
Extremity edema
Presence of collaterals
Differential extremity size
Current or previous subclavian catheter
placement of any type in venous drainage
of planned access
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VENOGRAHY: Indications
Current or previous transvenouspacemaker in venous drainage of planned
access Previous arm, neck, or chest trauma or
surgery in venous drainage of plannedaccess
Multiple previous accesses in an extremityplanned as an access site
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Arteriography: indications
Diminished pulses in desired extremity
BP difference of > 20 mm Hg between
arms.
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Assessment of the New
AVF for Maturity
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Fistula Maturation
Definition: Process by which a fistula becomes
suitable for cannulation (ie, develops adequate
flow, wall thickness, and diameter) Rule of 6s: In general, a mature fistula should:
Be a minimum of 6 mm in diameter with discernible
margins when a tourniquet is in place
Be less than 6 mm deep Have a blood flow greater than 600 mL/min
Be evaluated for nonmaturation 46 weeks after
surgical creation if it does not meet the above criteria
National Kidney Foundation.Am J Kidney Dis.2006;48(suppl 1):S1-S322.
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During AVF Maturation Process
Look, listen, and feel the new AVF atevery dialysis treatment
After the scar heals, begin assessing AVFusing a gentle tourniquet placed high inthe axilla area
Instruct patient to start access exercises
after healing (check with surgeon first) Document patient education as well as
condition and maturation of the AVF
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During Maturation
Feel for strong thrill at arterial anastomosis
Listen for continuous low-pitched bruit
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During Physical Examination
Assess AVF for complications
Thrombosis
Stenosis
Infection
Steal syndrome
Aneurysms
Select cannulation sites
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Fistula Maturation
What diagnostic tools or techniques can
be used to determine if an AVF is ready
for cannulation?
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Diagnostic Tools/Techniques toDetermine If an AVF Is Ready
Duplex Doppler study
Physical exam by the:
Nephrologist
Nephrology nurse
Surgeon
Angiogram (fistulogram)
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Best Tool/Technique?
Physical Exam!
Look, Listen, and Feel
Use Your:
Eyes
Ears
Fingertips
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Assessment of the AVF
for Complications
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Look for Complications
Changes in Access
Redness
Drainage Infection Abscess
Cannulation sites
Aneurysms
Changes in Access
Extremity
Skin color
Edema Small blue
or purple
veins
Hematoma
Bruising
Distal Areas of Access
Extremity Hands/Feet:
Cold
Painful StealNumb syndrome
Fingers/Toes:
Discolored
Central
oroutflow
vein
stenosis
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Stenosis
Harbinger of
thrombosis.
Reduces blood flowrate underdialysis.
Cause: fibrosis
following needle stick
injuries, abscess,pseudoaneurysm.
Stenosis
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Observe Access Extremityfor Stenosis Before the patient has needles inserted
Make a fist with access arm dependent;
observe vein filling
Raise access arm; entire AVF should flatten/
collapse if no stenosis/obstruction
If a segment of the AVF has not collapsed,
stenosis is located at junction betweencollapsed and noncollapsed segment
Instruct patient to perform this at home
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Stenosis
An increase in the intensity of the thrill, or
the pitch of the bruit as one moves the
finger/ stethescope along the midportion ofthe draining vein implies stenosis.
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Other methods of predicting
stenosis: MEAURING ACCESS
FLOW
DIRECT: Indicator dilution method
DopplerMRA
INDIRECT: serial measurement of intra
access pressure.
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Access flow measurements.
Flow through AV fistula averages 500-800
ml per min.
KDOQI reccomends to intervene if flowrate is < 600 ml/min, or there is decrease
in flow rate by > 25% over the preceding 4
months.
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INTERVENTION FOR STENOSIS
PTCA or revision surgery in a pt with >50% stenosis with 1 or more of following:
abnormal physical examination previous h/o thrombosis
decreasing access flow.
elevated or increasing intra accesspresure.
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Ischemia in a limb bearing AV
acess Ischemia distal to AVF can occur any time.
Incidence 2-5 %
Common in : DM, elderly, H/o CAD/PAD.
Arm fistulas.
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Vascular AccessInduced
Ischemia C/F: numbness, tingling, pain, motor
weakness
Signs: changes in skin color, temperature,loss of sensation, loss of motor fumction,
or loss of distal arterial pulses, and
development of arm edema whencompared to other side.
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Vascular AccessInduced
Ischemia Grade 1: pale/blue or cold hand without
pain
Grade 2: pain during exercise or HD
Grade 3: ischemic pain at rest
Grade 4: ulceration, necrosis, and
gangrene
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DIAGNOSING ISCHEMIA
Physical examination alone is inadequate.
Additional noninvasive testing with
measurement of digital pressures andcalculation of the digit to brachial index,transcutaneous oximetry, ultrasound offorearm arteries, and access blood flow
measurement are important steps in thediagnosis and decision-making process.
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TO CONCLUDE:
Vascular access created with minimal delay.
Have a functional fistula prior to initiate HD.
Minimize CV catheter usage. A multidisciplinary approach to access creation
and maintenance, involving nephrologists,interventional radiologists, access surgeons, and
dialysis nurses, is mandatory to meet the burdenof HD vascular access on health care facilitiesand costs
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THANK YOU
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REFERENCES
Dialysis access: current practice
Comprehensive Clinical Nephrology
Hand Book of Dialysis
Current Management of Vascular Access: Review article-Clin J AmSoc Nephrol2: 786800, 2007.
KDOQI 2006 guidelines
Fistula first initiative guidelines.