Aparato de Golgi
Mar 26, 2015
Aparato de Golgi
Figure 13-26a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-26b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-25b Molecular Biology of the Cell (© Garland Science 2008)
• Síntesis de carbohidratos.
• Clasificación y envío de productos.
Dictiosoma
Figure 13-25a Molecular Biology of the Cell (© Garland Science 2008)
(Entrada)
(Salida)
Polarización:cis-medial-trans
Figure 13-20 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-23b Molecular Biology of the Cell (© Garland Science 2008)
Ruta de biosíntesis - secreción
Figure 13-23b Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-50 Molecular Biology of the Cell (© Garland Science 2008)
Glucosilación (N-oligosacárido)
Figure 13-30 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-28 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-29 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-34 Molecular Biology of the Cell (© Garland Science 2008)
Ventajas de la glicosilación:
• Protección frente a proteasas
• Flexibilidad de membrana
• Reconocimiento antigénico
Figure 13-35a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-35b Molecular Biology of the Cell (© Garland Science 2008)
Matriz de Golgi
Science 305:48-9 (2004)
Lisosomas
Lisosomas: digestión intracelular de macromoléculas
Figure 13-36 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-37 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-38 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-3b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-42a Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-50 Molecular Biology of the Cell (© Garland Science 2008)
Glucosilación (N-oligosacárido)
Hidrolasas lisosómicas contienen Manosa-6-P
Figure 13-44 Molecular Biology of the Cell (© Garland Science 2008)
Endocitosis
Fagocitosis
Pinocitosis
Figure 13-47a Molecular Biology of the Cell (© Garland Science 2008)
100.000.000.000eritrocitos/día
Macrófagos: eliminación decélulas senescentes y apoptóticas
Figure 13-42a Molecular Biology of the Cell (© Garland Science 2008)
Pinocitosis: proceso constitutivo (reciclaje membrana)
Fagocitosis: requiere activación de receptores
Figure 13-8 Molecular Biology of the Cell (© Garland Science 2008)
Recubrimiento de Clatrina
Figure 13-48 Molecular Biology of the Cell (© Garland Science 2008)
Las vesículas de pinocitosis suelen estar recubiertas de clatrina
Figure 13-49 Molecular Biology of the Cell (© Garland Science 2008)
Algunas vesículas no están recubiertas por clatrina (caveolas)
Figure 13-50 Molecular Biology of the Cell (© Garland Science 2008)
Endocitosis mediadapor receptor:
endocitosis departículas LDL
Figure 13-51 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-53 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-52 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-56 Molecular Biology of the Cell (© Garland Science 2008)
Cuerpos multivesiculares
Figure 13-57 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-52 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-60 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-62 Molecular Biology of the Cell (© Garland Science 2008)