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Addressing the Threat of H1N1 Wednesday, October 21, 2009 Presented by: Procter & Gamble Professional
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Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

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Page 1: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Addressing the Threat of H1N1

Wednesday, October 21, 2009

Presented by:

Procter & Gamble Professional

Page 2: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

H1N1 Webinar

• H1N1 Overview

• The Impact of 2009 H1N1 Flu

• Controlling the Spread of Influenza Virus

• Recommended Cleaning Procedures

• Q&A

Page 3: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Our Experts

• Jeff Lange, PhD

– Epidemiologist, P&G Healthcare

• University of Iowa, Environmental and Occupational Health

• Cincinnati Health Department Board Member

• Tom Bell, PhD

– Product Safety and Regulatory Affairs, P&G Professional

• Ohio State University - Microbiology and Physiology

• Registered Sanitarian

• Matt Koloseike

– Customer Business Development Manager,

P&G Professional

• Cleaning Industry Management Standard (CIMS), ISSA

Certification Expert

Page 4: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Influenza Season

2009-2010

H1N1 and the Seasonal Flu

Page 5: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What is Influenza?

• A group of viruses that

cause contagious

respiratory disease.

• Virus characteristics are

always changing.

– Seasonal flu

• Novel strains can emerge

to infect humans.

– H1N1 - swine flu

– H5N1 - avian flu

Page 6: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

The H1N1 Flu Pandemic

• Novel flu strain that

has spread easily

from person-to-

person around the

world causing illness.

• First detected in U.S.

in April 2009.

Page 7: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What is the Current Status?

Source:

http://www.cdc.gov/flu/weekly/

Page 8: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What is the Current Status?

Occurrence of Influenza-Like Illness

Source:

http://www.cdc.gov/flu/weekly/

Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun

% o

f vis

its

fo

rin

flu

en

za

-lik

e i

lln

es

s

0

1

2

3

4

5

6

7

2007 - 2008

2005 - 2006

2006 - 2007

Page 9: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What is the Current Status?

Occurrence of Influenza-Like Illness

Source:

http://www.cdc.gov/flu/weekly/

Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun

% o

f vis

its f

or

infl

uen

za-l

ike ill

ness

0

1

2

3

4

5

6

7

2007 - 2008

2005 - 2006

2006 - 2007

2008 - 2009

First cases of

H1N1 flu

Page 10: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What is the Current Status?

Occurrence of Influenza-Like Illness

Source:

http://www.cdc.gov/flu/weekly/

Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun

% o

f vis

its f

or

infl

uen

za-l

ike ill

ness

0

1

2

3

4

5

6

7

2007 - 2008

2005 - 2006

2006 - 2007

2008 - 2009

2009 - 2010through October 10

Page 11: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

What are the Symptoms?

Symptoms Cold Flu

Fever Rare Usual; high (100-102oF);

occasionally higher last 3-4 days

Headache Rare Common

Muscle aches Slight Usual; often severe

Fatigue Sometimes Usual; can last 2 to 3 weeks

Extreme exhaustion Never Usual; at the start of illness

Stuffy nose Common Sometimes

Sneezing Usual Sometimes

Sore Throat Common Sometimes

Chest discomfort, cough Mild; hacking cough Common; can be severe

Complications Sinus congestion,

ear infection

Bronchitis, pneumonia; can be

life threatening

Source:

National Institute of Allergy and Infectious Disease "Is it a cold or the flu?" www.niaid.nih.gov

Page 12: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Why the Concern?

Source:

Jain S et al. Hospitalized Patients with 2009 H1N1 Influenza in the United States, April-June 2009. N Engl J Med. 2009 Oct 8

Kumar A et al. Critically Ill Patients with 2009 Influenza A(H1N1) Infection in Canada. JAMA. 2009 Oct 12

Typical Season 2009-2010 Season to Date

Peak of season in February Spring, summer, fall, ???

15 – 60 million illnesses Likely already millions

200,000 hospitalizations

36,000 deaths, many age 65+

Children and young adults,

average age 35

Disproportionately high fatality rate

in pregnant women

Average of 87 deaths in pediatrics

through winter

86 deaths in pediatrics from H1N1

as of October 9

Page 13: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

How Does Influenza Spread?

New Person

New Person

Surfaces New Person

Infected person creates:

Aerosols

Droplets

Page 14: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Influenza Prevention

• Personal hygiene

• Stay home if sick

• Clean work surfaces/tools

• Two vaccinations

– Seasonal flu

– H1N1 flu

• Stay informed at local

levelSource:

http://www.cdc.gov/h1n1flu/business

http://www.cdc.gov/flu/protect/covercough.htm

Page 15: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Influenza Vaccination

Seasonal

Flu Vaccine

H1N1

Flu Vaccine

Protects against 3 types of flu Protects against 1 type of flu

Both seasonal and H1N1 flu vaccines have been produced by the same

manufactures using the same processes

Nasal FluMist or

Injectable shot

Nasal FluMist or

Injectable shot

Widely available now

Becoming available now to high risk

groups and wider availability by

middle of November

Page 16: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Which Flu Vaccine to Receive?

• CDC recommends both vaccines for:

– Pregnant women

– People who care for children younger than 6 months of age

– Health care and emergency medical services personnel

– Persons ages 6 months through 18 years old

– Persons ages 19-64 with chronic conditions

• CDC recommends neither vaccine for:

– Infants younger than 6 months

– Those with a history of serious allergic reaction to flu vaccine

– Those with a history of serious allergic reaction to eggs

– Those currently with an acute illness, delay until well

Source:

CDC’s Advisory Committee on Immunization Practices

Page 17: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Which Flu Vaccine to Receive?

• Healthy adults ages 19-24

– H1N1 vaccine

– Seasonal vaccine, in most cases, is not considered essential

• Healthy adults ages 24-49

– H1N1 vaccine – when supplies are adequate

– Seasonal vaccine is not considered essential

• Healthy adults ages 50-64

– H1N1 vaccine – when supplies are adequate

– Seasonal vaccine

• Adults ages 65 or older

– H1N1 vaccine – when supplies are adequate for this group

– Seasonal vaccine as soon as possibleSource:

CDC’s Advisory Committee on Immunization Practices

Page 18: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Stay Informed with Local Experts

Page 19: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Additional Flu Information

www.flu.gov

• Compilation of information from

CDC, WHO and other experts

www.cdc.gov/h1n1flu/business

• For guidance and materials

Page 20: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Recommended Cleaning Procedures

Page 21: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

H1N1 Viral Transmission

Where do the viruses from

airborne release go?

Page 22: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Where Does the Virus Go?

• Spread of H1N1 virus

– Infectious virus is

airborne from person

– Airborne virus deposits

on surfaces

– Virus survival on the

surface for 8+ hours

– Virus from surface to

person

– More people get sick

Sick

Sneeze

AirborneSurfaces

Hands

Page 23: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Break the Cycle

What kills influenza virus?

• Chemical germicides

– chlorine, hydrogen, peroxide, quaternary

compounds, detergents (soap), iodophors

(iodine-based antiseptics) and alcohols are

effective against human influenza viruses if

used in proper concentration for a sufficient

length of time. Use registered products

according to label instructions.

• Extreme heat: 167°-212°FSource:

http://www.cdc.gov/ncidod/dhqp/pdf/guidelines/Disinfection_Nov_2008.pdf

Page 24: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

H1N1 is a Virus

• Capsule of the virus

is made of protein.

• Disinfectants alter

the viral protein.

• Damage to the viral

protein deactivates

the virus.

Page 25: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Germicidal Mode of Action

Three classes of germicidal products:

1. Quaternary ammonium compounds

denature the proteins

2. Alcohol causes protein coagulation and

denaturation

3. Chlorine compounds have been shown to

affect surface antigen in viruses and DNA

Result: the virus is neutralized

Page 26: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Cleaning & Disinfection

• P&G’s comprehensive sanitation programs (including products

and procedures) are designed to help prevent the general

transmission of viruses and other pathogens that cause illness.

• We recommend cleaning and disinfecting surfaces with P&G

Professional, EPA-registered hospital detergent/disinfectants,

paying particular attention to those that are frequently touched

(especially in customer or high use areas).

• Examples include:

Shopping cart handles

Door knob handles

Sink faucets

Food trays

Counter tops

Phones

Chairs

Tables

Handrails

Elevator buttons

Light switches

Work out equipment

Cash registers

Toilet handles

Office equipment

Page 27: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Recommended Cleaning Products

Page 28: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

PGP Cleaning & Disinfection

Products

Disinfection and H1N1

• The EPA believes, based on available scientific information, that

the currently registered influenza A virus products will be

effective against the Novel H1N1 flu strain and other influenza A

virus strains on hard, nonporous surfaces.

• The following P&G products are listed among the products that

meet EPA criteria being effective against the Novel H1N1 flu

strain:

Spic and Span Disinfecting All-Purpose Spray and Glass Cleaner (ready to use form)EPA Registration Number 6836-245-3573

Spic and Span Disinfecting All-Purpose Spray and Glass Cleaner (concentrate form) EPA Registration Number 6836-244-3573

Comet Disinfecting Bathroom Cleaner (ready to use form)EPA Registration Number 3573-54

P&G Pro Line Disinfecting Floor Cleaner (with optional usage as a spray product)EPA Registration Number 8155-23-3573

Clean Quick Broad Range Quaternary Sanitizer (following disinfection procedures)EPA Registration Number 6836-278-3573

Page 29: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

Surface Cleaning and Disinfection

Spic & Span® Disinfecting All-Purpose Spray

and Glass Cleaner*

• Should be used to clean and disinfect dry

surfaces, focusing on those that are frequently

touched by multiple people. EPA registration

number 6836-244-3573.

Comet® Disinfecting Bathroom Cleaner*

• Should be used to clean and disinfect surfaces

exposed to water (showers, sinks, etc.) EPA

registration number 3573-54.

*Indicates EPA-registered product for Influenza A

Page 30: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

Floor Disinfection

P&G Pro Line Disinfectant Floor Cleaner*

• Combines activity of dialkyl quat with

powerful cleaning agents, buffered to a

neutral pH for no-rinse cleaning and

disinfecting. One-step cleaner, disinfectant,

and deodorizer. Can also be diluted for

spray usage. EPA registration number

8155-23-3573.

*Indicates EPA-registered product for Influenza A

Page 31: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

Surface Sanitation

Clean Quick® Sanitizers (quaternary ammonium and chlorine

based)*

• Can be used to sanitize surfaces. EPA registration numbers

1275-27-3573 (chlorine sanitizer and cleaner), 10634-19-3573

(packets), 6836-278-3573 (broad range quat sanitizer red).

*Indicates EPA-registered product for Influenza A

Page 32: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

Personal Hygiene

Safeguard® Hand Soap

• Soap and water should be used to frequently

wash hands. Washing your hands for at least

20 seconds is known to reduce the spread of

germs.

DCT Hand Sanitizer

• Can be considered for use in customer and/or

worker areas. Recommended when soap and

water are not available. This product conforms

to the CDC recommendations as an alcohol-

based topical hand sanitizer.

Page 33: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

General Surface Cleaning

Comet® Cleaner with Bleach

• Can be used to clean multiple surfaces,

focusing on those that are frequently touched

by multiple people. This product is not a

registered disinfectant.

Page 34: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Products for Your Cleaning Program:

Toilet Cleaning

Mr. Clean Toilet Bowl Disinfectant

P&G Pro Line Thickened Acid Toilet Bowl Cleaner

• Ultra-thick detergents and highly effective acid formulae

removes and helps keep toilet bowls and urinals free of hard

water build-up. Both products clean, disinfect, deodorize and

remove mineral deposit and rust. EPA registration numbers

3573-53 and 8155-6-3573.

Page 35: Addressing the Threat of H1N1 - Procter & Gamble · 2018-10-04 · Three classes of germicidal products: 1. Quaternary ammonium compounds denature the proteins 2. Alcohol causes protein

Questions & Answers