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About Schizophrenia: The Disease And Treatment Approaches (NAPSA)—Schizophrenia is a chronic, severe and disabling brain disorder affecting approximately 1.1 percent of American adults, but it can be treated. 1 People living with schizophrenia may experience symptoms such as hallucinations, which include hearing voices or seeing things that are not there. Others may experience delusions, such as believing people are controlling their minds and influencing their thoughts, or making plans to harm them. Many deal with disruptions to normal emotions or behaviors, such as lack of emotions, social withdrawal or disorganized thinking. 2,3 These various symptoms can be devastating and scary to people with the illness, potentially causing them to withdraw or become agitated. It can be equally devastating and scary to the people around them. Schizophrenia not only affects the people living with the disease but also their loved ones, sometimes many years before diagnosis. One of the most significant aspects of the disease is that it is not easily nor efficiently diagnosed, and the illness may go undiagnosed—and therefore untreated—after the onset of the first symptoms. 4 Approximately half of the people living with schizophrenia do not understand that they have the illness. 5 Further, it can be hard for some people with schizophrenia to understand it is a lifelong disease, requiring adequate, consistent treatment and support. 6 Schizophrenia has historically been misunderstood in the U.S. People living with schizophrenia tended to reside on the streets or were incarcerated in asylums, jails or prisons prior to 1800. Beginning in the 1900s, people were hospitalized, but the early 20 th century brought about various treatments. Specific medications for schizophrenia symptoms were first used in the 1950s. Deinstitutionalization, starting in the 1960s, led to the release of people with stable schizophrenia from state hospitals. However, these individuals continued to suffer with poor health due to the lack of stable living arrangements, misuse of funds, poor medical follow-up and drug use. 7 A more recent understanding of the biological basis and advances in medications has helped to place the disease in a less stigmatized and more treatable light. If treated continuously and early, schizophrenia may be more manageable. 8 It can be treated in several ways, including antipsychotic medications, which are available in pill or liquid form taken daily. Antipsychotics are also available by injection given once every two weeks or six weeks, or once every month or three months. These long-acting injectable antipsychotics provide patients with medication that remains within the body for an extended period of time. 9 Additional forms of treatment include psychotherapy, such as cognitive behavioral therapy and supportive therapy, as well as self- management strategies and education. A person’s treatment regimen is critical to managing the disease. Individuals with schizophrenia may experience relapses—a worsening of symptoms—following a period of stability. 10 There are potentially significant effects associated with relapse, including evidence to suggest that multiple relapses over an extended period may lower brain functioning. It is important to maintain treatment and follow an established treatment plan. 11,12 “It is crucial to find a tailored treatment approach for those living with this debilitating disease. Further, everyone’s brain responds differently to medications, so it is critical that patients work closely with their physician in order to figure out what works best and is tolerable for them. In many cases, this may involve cycling through different options,” explained Andrew Cutler, M.D., Chief Medical Officer of Meridien Research in Bradenton, Florida. “Once a person finds a treatment path that is right for them, they’re often able to cope with their symptoms and maximize their functioning.” To learn more about treatment options for schizophrenia, visit: http://www.mentalhealthamerica. net/medication. 1 National Institute of Mental Health. Schizophrenia. Retrieved June 28, 2016 from http://www.nimh.nih.gov/health/statistics/prevalence/schizophrenia.shtml 2 American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). 3 National Institute of Mental Health. Schizophrenia. Retrieved June 28, 2016 from http://www.nimh.nih.gov/health/topics/schizophrenia/index.shtml#part_145430 4 O’Callaghan E et al. (2010). First episode psychosis and the trail to secondary care: help-seeking and health-system delays. Social Psychiatry and Psychiatric Epidemiology, 45(3): 381–91. 5 National Alliance on Mental Illness. Anosognosia (Lack of Insight) Fact Sheet. Retrieved June 28, 2016 from http://www.namistl.org/uploads/1/5/4/9/15496234/anosognosia_factsheet.pdf 6 Brain & Behavior Research Foundation. Frequently Asked Questions about Schizophrenia. Retrieved June 28, 2016 from https://bbrfoundation.org/frequently-asked-questions-about-schizophrenia 7 Tueth M. (1995). Schizophrenia: Emil kraepelin, Adolph Meyer, and beyond. The Journal of Emergency Medicine. 13(6): 805-809. 8 American Psychiatry Association. (2004). Practice Guideline For The Treatment of Patients With Schizophrenia (2nd ed.). 9 National Alliance on Mental Illness. Long-acting Injectable Antipsychotics Fact Sheet. Retrieved June 28, 2016 from http://www2.nami.org/factsheets/LAI_factsheet.pdf 10 Lader M. (1995). What is a relapse in schizophrenia? Int Clin Psychopharmacol, 1995; 5:5-9. 11 Andreasen NC et al. (2013). Relapse Duration, Treatment Intensity, and Brain Tissue Loss in Schizophrenia: A Prospective Longitudinal MRI Study. American Journal of Psychiatry. 170(6): 609-615. 12 Lieberman JA et al. (2002). The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches. Biol Psychiatry, 50(11): 884-897 OT-001329
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About Schizophrenia: The Disease And Treatment Approaches ... · Beginning in the 1900s, people were hospitalized, but the early 20 th century brought about various treatments. ...

Jan 25, 2019

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Page 1: About Schizophrenia: The Disease And Treatment Approaches ... · Beginning in the 1900s, people were hospitalized, but the early 20 th century brought about various treatments. ...

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About Schizophrenia: The Disease And Treatment Approaches(NAPSA)—Schizophrenia is a

chronic, severe and disabling braindisorder affecting approximately1.1 percent of American adults, butit can be treated.1 People livingwith schizophrenia may experiencesymptoms such as hallucinations,which include hearing voices orseeing things that are not there.Others may experience delusions,such as believing people arecontrolling their minds andinfluencing their thoughts, ormaking plans to harm them. Manydeal with disruptions to normalemotions or behaviors, such as lackof emotions, social withdrawal ordisorganized thinking.2,3 Thesevarious symptoms can bedevastating and scary to peoplewith the illness, potentiallycausing them to withdraw orbecome agitated. It can be equallydevastating and scary to the peoplearound them. Schizophrenia notonly affects the people living withthe disease but also their lovedones, sometimes many years beforediagnosis.One of the most significant

aspects of the disease is that itis not easily nor eff icientlydiagnosed, and the illness maygo undiagnosed—and thereforeuntreated—after the onset of thefirst symptoms.4 Approximatelyhalf of the people living withschizophrenia do not understandthat they have the i l lness. 5Further, it can be hard for somepeople with schizophrenia tounderstand it is a l i felongdisease, requiring adequate,

consistent treatment andsupport.6Schizophrenia has historically

been misunderstood in the U.S.People living with schizophreniatended to reside on the streets orwere incarcerated in asylums,jails or prisons prior to 1800.Beginning in the 1900s, peoplewere hospitalized, but the early20

thcentury brought about

various treatments. Specif icmedications for schizophreniasymptoms were first used in the1950s. Deinstitutionalization,starting in the 1960s, led to therelease of people with stableschizophrenia from statehospitals. However, theseindividuals continued to sufferwith poor health due to the lackof stable living arrangements,misuse of funds, poor medicalfollow-up and drug use.7 A morerecent understanding of thebiological basis and advances inmedications has helped to placethe disease in a less stigmatizedand more treatable light.If treated continuously and

early, schizophrenia may be moremanageable.8 It can be treated inseveral ways, includingantipsychotic medications, whichare available in pill or liquid formtaken daily. Antipsychotics arealso available by injection givenonce every two weeks or sixweeks, or once every month orthree months. These long-actinginjectable antipsychotics providepatients with medication thatremains within the body for an

extended period of time.9Additional forms of treatmentinclude psychotherapy, such ascognitive behavioral therapy andsupportive therapy, as well as self-management strategies andeducation.A person’s treatment regimen is

critical to managing the disease.Individuals with schizophreniamay experience relapses—aworsening of symptoms—followinga period of stability.10 There arepotentially significant effectsassociated with relapse, includingevidence to suggest that multiplerelapses over an extended periodmay lower brain functioning. It isimportant to maintain treatmentand follow an establishedtreatment plan.11,12“It is crucial to find a tailored

treatment approach for those livingwith this debilitating disease.Further, everyone’s brain respondsdifferently to medications, so it iscritical that patients work closelywith their physician in order tofigure out what works best and istolerable for them. In many cases,this may involve cycling throughdifferent options,” explainedAndrew Cutler, M.D., Chief MedicalOfficer of Meridien Research inBradenton, Florida. “Once a personfinds a treatment path that is rightfor them, they’re often able to copewith their symptoms and maximizetheir functioning.”To learn more about treatment

options for schizophrenia, visit:http://www.mentalhealthamerica.net/medication.

1 National Institute of Mental Health. Schizophrenia. Retrieved June 28, 2016 fromhttp://www.nimh.nih.gov/health/statistics/prevalence/schizophrenia.shtml2 American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.).3 National Institute of Mental Health. Schizophrenia. Retrieved June 28, 2016 fromhttp://www.nimh.nih.gov/health/topics/schizophrenia/index.shtml#part_1454304 O’Callaghan E et al. (2010). First episode psychosis and the trail to secondary care: help-seeking and health-system delays. Social Psychiatryand Psychiatric Epidemiology, 45(3): 381–91.5 National Alliance on Mental Illness. Anosognosia (Lack of Insight) Fact Sheet. Retrieved June 28, 2016 fromhttp://www.namistl.org/uploads/1/5/4/9/15496234/anosognosia_factsheet.pdf6 Brain & Behavior Research Foundation. Frequently Asked Questions about Schizophrenia. Retrieved June 28, 2016 fromhttps://bbrfoundation.org/frequently-asked-questions-about-schizophrenia7 Tueth M. (1995). Schizophrenia: Emil kraepelin, Adolph Meyer, and beyond. The Journal of Emergency Medicine. 13(6): 805-809.8 American Psychiatry Association. (2004). Practice Guideline For The Treatment of Patients With Schizophrenia (2nd ed.).9 National Alliance on Mental Illness. Long-acting Injectable Antipsychotics Fact Sheet. Retrieved June 28, 2016 fromhttp://www2.nami.org/factsheets/LAI_factsheet.pdf10 Lader M. (1995). What is a relapse in schizophrenia? Int Clin Psychopharmacol, 1995; 5:5-9.11 Andreasen NC et al. (2013). Relapse Duration, Treatment Intensity, and Brain Tissue Loss in Schizophrenia: A ProspectiveLongitudinal MRI Study. American Journal of Psychiatry. 170(6): 609-615.12 Lieberman JA et al. (2002). The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches.Biol Psychiatry, 50(11): 884-897

OT-001329

(NAPSA)—Here’s more “berry”good health news: Clinical researchsuggests that eating just one serv-ing of eight strawberries a day—freshor frozen—may improve heart health,reduce the risk of some cancers andsupport brain health. Additionally,the American Diabetes Associationidentifies berries, including straw-berries, as one of the top 10 super-foods for a diabetes meal plan becausethey are low in sugar (just 7g) andcalories (just 45 calories), and packedwith vitamins (more vitamin C perserving than an orange), antioxidantsand dietary fiber (3g). When addedup, strawberries provide a nutritiousboost for the entire body.New research conducted at the

USDA Human Nutrition ResearchCenter on Aging at Tufts Univer-sity and presented to the Societyfor Neuroscience revealed thatstrawberries might effectivelycombat age-related cognitivedecline. In clinical studies, USDAresearchers demonstrated thatsupplementing older adults’ dietswith about two cups a day ofstrawberries could improve cogni-tion even in the absence of neuro-logical dysfunction.For the trial, healthy men and

women, age 60 to 75, consumedeither the equivalent of about twocups per day of fresh strawberriesin the form of a freeze-dried pow-der or an equal amount of a calo-rie-matched control powder con-taining no strawberries, for 90days. The participants maintainedtheir normal diet, other thanrefraining from consuming anyberries or berry products duringthe study. Dietary interventionwith strawberries for 90 days ledto improvements in spatial mem-ory and word recognition amongthese healthy older adults. Over-all, the study results suggest thatdietary intervention with straw-berry fruit may be an effectivemeans of combating age-relatedcognitive decline.“This new study about straw-

berries supporting cognitive healthadds further strength to the clini-cal research around the healthbenefits of strawberries,” saidSylvia Klinger, registered dietitian.She added, “Eating eight strawber-ries a day is a good habit to

develop no matter what stage oflife we’re in.”As one of the most versatile

fruits—and a delight for the tastebuds—strawberries are easy toenjoy daily just as they are, or in avariety of simple, savory or sweetrecipes.Naturally sweet and delicious,

here’s a simple way to enjoystrawberries:

Cool Red Strawberry SmoothieServes: 4

1 cup grape juice1 tablespoon lemon zest5 cups fresh Californiastrawberries, stemmed

6 to 8 fresh mint leaves1 medium fresh beet, cookedor canned

1 large carrot, cut intochunks

2 tablespoons honey(optional)

Add all ingredients to a largeblender; process until smooth.For a sorbet consistency, usewhole frozen strawberries.Nutrition per Serving: Calories,

110; Fat, 0g; Cholesterol, 0mg;Sodium, 25mg; Carbohydrates,26g; Fiber, 5g; Protein, 2g.

Learn MoreFor more information, visit

www.californiastrawberries.com.

Brain Booster: Strawberries May CombatAge-Related Cognitive Decline

Studies show strawberries in thedaily diet are good for the mind,heart and body.

***Courage is fear holding on a minute longer.

—General George S. Patton***

***The man who has no inner life is the slave of his surroundings.

—Henri-Frédéric Amiel***

***To withhold news is to play God.

—John Hess***

***Do not ask yourself what the world needs; ask yourself whatmakes you come alive. And then go and do that. Because whatthe world needs is people who have come alive.

—Harold Whitman***

***It is not because things are difficult that we do not dare, it isbecause we do not dare that they are difficult.

—Seneca***

***Be bold and mighty forces will come to your aid.

—Basil King***

***The art of being wise is the art of knowing what to overlook.

—William James***

***The keenest sorrow is to recognize ourselves as the sole causeof all our adversities.

—Sophocles***

***Life is a foreign language. All men mispronounce it.

—Christopher Morley***

***Love is the triumph of imagination over intelligence.

—H.L. Mencken***

***I’ve never known any trouble that an hour’s reading did notassuage.

—Charles Louis de Secondat***

***The best bridge between despair and hope is a good night’ssleep.

—E. Joseph Cossman***

A rat can go without water for alonger period of time than a camelcan.

A beaver can hold its breath forabout 45 minutes.