4th Annual Advances in Colorectal Oncologyin the management of advanced colorectal cancer. 2) Increase the learner’s ability to integrate the various aspects of metastatic colorectal

November 7Advances in Robotic Colorectal and Hepatopancreatobiliary Surgery Hosted by MSK and MD Anderson Cancer Center

November 8-9 Regional Therapy for Advanced and Metastatic Colorectal and Appendiceal Cancers

4th Annual Advances in Colorectal Oncology

Memorial Sloan Kettering Cancer Center presents the

This three day conference will provide attendees with up-to-date information on the biology, diagnosis, and treatment of colorectal cancer. In addition to lectures, the conference will include opportunities for interactive exchange of ideas between participants and faculty. Registration discount available for both symposiums.

November 7

Advances in Robotic Colorectal and Hepatopancreatobiliary Surgery

Hosted by Memorial Sloan Kettering and MD Anderson Cancer Center, this symposium will include live and recorded demonstrations of surgical techniques, detailed step-by-step analysis of surgical procedures, and presentations by experts on the latest advances in the use of robotic technology for minimally invasive surgical treatment of colorectal cancer.

Attendees are invited to join the course faculty for a Cocktail Reception and Poster Session on Thursday evening.

November 8-9

Regional Therapy for Advanced and Metastatic Colorectal and Appendiceal Cancers

International thought leaders will present the latest advances in regional and systemic treatment strategies for metastatic colorectal and appendiceal cancers. Research discoveries are opening up opportunities for greater personalization of treatment. A challenge facing oncology care teams and healthcare systems is the identification and timely integration of important treatment innovations developed at specialty centers into day-to-day clinical practice in the community setting, closer to where patients live. A central goal of this CME course is to provide busy specialists (oncologists, surgeons, interventional radiologists, radiation oncologists, radiologists, pathologists) with clinically relevant, cutting-edge knowledge that will help them translate those innovations into best practices, as is being done at various member institutions of the MSK Cancer Alliance. The second day of the conference will follow a case-based format using real-life clinical scenarios. The moderator of each multidisciplinary panel of international experts will incorporate audience responses in examining key decision points and guiding targeted commentary on presentations by the panelists.

Rectal MRI Workshop

This hands-on workshop for practicing radiologists, radiologists in training, and anyone with an interest in pelvic MRI will run concurrently with the symposium on robotics. For details and registration, visit mskcc.org/RectalMRI.

“World class speakers and faculty; excellent program.”

“I enjoyed learning from the live OR feeds.”

“Outstanding program; I would come again.”

- 2018 attendee feedback CALL FOR ABSTRACTS

Participants are invited to submit an abstract for presentation at the poster session. Abstracts will be selected on the basis of scientific merit and presentation quality. Three travel grants will be awarded: Attendings’ Choice Award, Best Resident/Fellow Award and People’s Choice Award.

Abstract submission deadline: October 31, 2019.

mskcc.org/colorectalcourse


Join the conversation #MSKcolorectalCME


Advances in Robotic Colorectal and Hepatopancreatobiliary Surgery Thursday, November 7

The University of Texas MD Anderson Cancer Center

Brian Bednarski, MDAssistant ProfessorAssociate Program Director, Complex General Surgical Oncology Fellowship

Natacha Cohen, PA-CDepartment of Surgery

José G. Guillem, MD, MPHAttending SurgeonColorectal Service Director, Hereditary Colorectal Cancer Family Registry

Vincent P. Laudone, MDChief of Surgery, Josie Robertson Surgery Center

Mario Leitao, MDFellowship Director, Gynecology ServiceDirector, Minimal Access and Robotic Surgery ProgramDepartment of Surgery

Emmanouil ‘Manny’ Pappou, MD, PhDAssistant AttendingColorectal Service Department of Surgery

Garrett M. Nash, MD, MPH Vice Chair for Quality and Safety Department of Surgery

Philip B. Paty, MDAttending SurgeonColorectal ServiceDepartment of Surgery

Memorial Sloan Kettering Cancer Center

Hosted by Memorial Sloan Kettering and MD Anderson Cancer Center, this symposium will include live and recorded demonstrations of surgical techniques, detailed step-by-step analysis of surgical procedures, and presentations by experts on the latest advances in the use of robotic technology for minimally invasive surgical treatment of colorectal cancer.

Learning Objectives 1) Understand the requirements for a successful advanced robotic program.

2) Become familiar with different approaches to minimally invasive transabdominal and transrectal colorectal procedures.

3) Become familiar with advanced hepatobiliary surgical techniques.

4) Review the principles of complete mesenteric excision in colorectal cancer.

Target Audience This symposium is intended for colon and rectal surgeons, hepatopancreatobiliary surgeons, general surgeons, surgical oncologists, fellows, residents, PAs, NPs, RNs, and anyone interested in learning about robotic

Cocktail Reception and Poster SessionAttendees are invited to join the course faculty for abstract poster presentations and a networking reception in the lobby of Zuckerman Research Center from 5:00-6:30 pm. Hors d’oeuvres and refreshments will be served.

Julio Garcia-Aguilar, MD, PhDBenno C. Schmidt Chair in Surgical OncologyChief, Colorectal ServiceDirector, Colorectal Cancer Research CenterDepartment of SurgeryProfessor of Surgery, Weill Cornell Medical CollegeMemorial Sloan Kettering Cancer CenterNew York, NY

George J. Chang, MDChief, Section of Colon and Rectal SurgeryDepartment of Surgical OncologyThe University of Texas MD Anderson Cancer Center Houston, TX

Course Directors

Course Faculty

Matthew Tillman, MDAssistant ProfessorDepartment of Surgical Oncology

Kevin Soares, MDAssistant Attending SurgeonHepatopancreatobiliary ServiceDepartment of Surgery

Yukio Sonoda, MDAttending SurgeonSection, Ovarian Cancer SurgeryDepartment of Surgery Iris H. Wei, MDAssistant AttendingColorectal Service Department of Surgery Martin R. Weiser, MDAttending Surgeon, Colorectal Surgery Vice Chair for Education and Faculty DevelopmentDepartment of SurgeryStuart H.Q. Quan Chair in Colorectal Surgery Maria Widmar, MD, MPHAssistant AttendingColorectal ServiceDepartment of Surgery


3:15 pm Break

3:45 pm Controversies/DiscussionCHAIR: José G. Guillem, MD, MPH

PANEL:

Philip B. Paty, MDIris H. Wei, MDBrian Bednarski, MDEmmanouil ‘Manny’ Pappou, MD, PhD

5:00 pm Adjourn

Cocktail Reception and Poster SessionAttendees are invited to join the course faculty for abstract poster presentations and a networking reception in the lobby of Zuckerman Research Center on Thursday evening from 5:00-6:30 pm. Hors d’oeuvres and refreshments will be served.

Schedule | Thursday, November 7

7:00 am Breakfast and Registration

7:40 am Introduction & Welcome Julio Garcia-Aguilar, MD, PhDBrian Bednarski, MD

Live Surgery, PresentationsA live surgery will be video streamed between the presentations.

SURGEONS:

Julio Garcia-Aguilar, MD, PhDGarrett M. Nash, MD, MPH Martin R. Weiser, MD Kevin Soares, MD Natacha Cohen, PA-C

7:45 am Session I Preliminaries CHAIR: Philip B. Paty, MD

a) Developing Robotic ProgramMario Leitao, MD

b) Room Set Up Natacha Cohen

c) StandardizationJosé G. Guillem, MD, MPH

8:30 am Session II Hepatic Artery Infusion Pump/Liver ResectionCHAIR: Alice Wei, MDPRESENTER: Kevin Soares

9:30 am Session III Right ColectomyCHAIR: Maria Widmar, MD, MPHPRESENTER: Matthew Tillman, MD

10:30 am Break

10:45 am Session IV Left Colectomy/Left Colon MobilizationCHAIR & PRESENTER: Emmanouil ‘Manny’ Pappou, MD, PhD

11:30 am Session V Total Mesorectal ExcisionCHAIR: Iris H. Wei, MDPRESENTER: Brian Bednarski, MD

12:30 pm Lunch

1:30 pm Session VI Lateral Pelvic Lymph Node Disection/Extended Resection CHAIR: Brian Bednarski, MDPRESENTERS: Vincent P. Laudone, MD and Yukio Sonoda, MD

2:30 pm Session VII TAMISCHAIR & PRESENTER: Philip B. Paty, MD


Julio Garcia-Aguilar, MD, PhDBenno C. Schmidt Chair in Surgical OncologyChief, Colorectal ServiceDirector, Colorectal Cancer Research CenterDepartment of SurgeryProfessor of Surgery, Weill Cornell Medical College

Andrea Cercek, MDAssistant Attending Department of Medicine

Rona D. Yaeger, MD Assistant AttendingMedical Oncology

MSK Course Directors

International thought leaders will present the latest advances in regional and systemic treatment strategies for metastatic colorectal and appendiceal cancers. Research discoveries are opening up opportunities for greater personalization of treatment. A challenge facing oncology care teams and healthcare systems is the identification and timely integration of important treatment innovations developed at specialty centers into day-to-day clinical practice in the community setting, closer to where patients live.

A central goal of this CME course is to provide busy specialists (oncologists, surgeons, interventional radiologists, radiation oncologists, radiologists, pathologists) with clinically relevant, cutting-edge knowledge that will help them translate those innovations into best practices, as is being done at various member institutions of the MSK Cancer Alliance.

The second day of the conference will follow a case-based format using real-life clinical scenarios. The moderator of each multidisciplinary panel of international experts will incorporate audience responses in examining key decision points and guiding targeted commentary on presentations by the panelists.

Learning Objectives 1) Update the learner on the progress made in the management of advanced colorectal cancer.

2) Increase the learner’s ability to integrate the various aspects of metastatic colorectal cancer management including timing of surgery, selection of modality for locoregional control, and use of systemic and regional therapies for the metastatic disease.

3) Increase the learner’s familiarity with genomic predictors of response to therapy.

4) Bring participants up to date with the use of immunotherapy and targeted therapy for metastatic disease.

5) Review the results of the most important clinical trials in stage IV colorectal cancer.

Target Audience

This symposium will help medical oncologists, radiation oncologists, interventional radiologists, colorectal/hepatopancreatobiliary/oncologic surgeons, gastroenterologists, pathologists, and other oncology care team members acquire clinically relevant, cutting-edge knowledge and translate it into best practices.

Regional Therapy for Advanced and Metastatic Colorectal and Appendiceal CancersFriday-Saturday, November 8-9

Christopher Crane, MDVice Chair, Department of Radiation Oncology

Louise C. Connell, MBAssistant AttendingDepartment of Medicine

Luis A. Diaz, MDGrayer Family ChairHead of the Division of Solid Tumor Oncology

Jeffrey Drebin, MD, PhDChair, Department of Surgery

Karuna Ganesh, MD, PhDAssistant Attending PhysicianDepartment of Medicine

Marc J. Gollub, MDDirector of CT and GI ImagingBody imaging ServiceDepartment of Radiology

William R. Jarnagin, MDAttending SurgeonChief, Hepatopancreatobiliary ServiceLeslie Blumgart Chair in Surgery Nancy E. Kemeny, MDAttendingMedical Oncology Bernard J. Park, MDAttendingDeputy Chief of Clinical AffairsThoracic Service

Philip B. Paty, MDAttending SurgeonColorectal ServiceDepartment of Surgery

Memorial Sloan Kettering Course Faculty

Andreas Rimner, MDAssociate AttendingDirector of Thoracic Radiation Oncology Research

Leonard Saltz, MDAttending PhysicianGastrointestinal Oncology Service

Constantinos T. Sofocleous, MD, PhDAttendingInterventional Radiologist Stephen Solomon, MDChief of Interventional Radiology Attending Radiologist Department of Radiology Professor of Radiology, Cornell University Efsevia Vakiani, MDAssociate AttendingDepartment of Pathology

Alice Wei, MDAssociate Attending Surgeon Hepatopancreatobiliary ServiceDepartment of SurgeryCo-Director of Surgical Initiatives,David M. Rubenstein Center for Pancreatic Cancer Research

Martin R. Weiser, MDAttending Surgeon, Colorectal SurgeryVice Chair for Education and Faculty DevelopmentDepartment of SurgeryStuart H.Q. Quan Chair in Colorectal Surgery Maria Widmar, MD, MPHAssistant AttendingColorectal ServiceDepartment of Surgery

Garrett M. Nash, MD, MPH Vice Chair for Quality and SafetyDepartment of Surgery

H. Richard Alexander, MD Chief Surgical OfficerRutgers Cancer Institute of New JerseyProfessor and Head, Division of Surgical OncologyDepartment of SurgeryRutgers Robert Wood Johnson Medical SchoolNew Brunswick, NJ

David L. Bartlett, MDBernard Fisher Professor of SurgeryVice Chairman for Surgical Oncology and

GI Surgical ServicesUniversity of Pittsburgh Medical Center Pittsburgh, PA

Brian Bednarski, MDAssistant ProfessorAssociate Program Director, Complex General Surgical Oncology FellowshipThe University of Texas MD Anderson Cancer CenterHouston, TX

George J. Chang, MDChief, Section of Colon and Rectal SurgeryDepartment of Surgical OncologyThe University of Texas MD Anderson Cancer Center Houston, TX

Yun Shin Chun, MDAssociate ProfessorDepartment of Surgical Oncology University of Texas The University of Texas MD Anderson Cancer Center Houston, TX Aasmund Avdem Fretland, MDConsultant SurgeonThe Intervention Centre and the Department

of HPB SurgeryOslo University HospitalOslo, Norway Dung Le, MDAssociate Professor of OncologyThe Johns Hopkins Hospital Baltimore, MD

Brendan Moran, MDConsultantHampshire Hospitals NHS Foundation TrustBasingstoke and North Hampshire HospitalBasingstoke, United Kingdom

David L. Morris, MD, PhDDepartment of Surgery, Peritonectomy UnitSt George Hospital and University of New South Wales Sydney, Australia

Invited Course Faculty

Francois Quenet, MDChirurgie OncologiqueInstitut du Cancer de MontpellierInstitut de Recherche en Cancerologie de Montpellier / INSERM U896France

Miguel Rodriguez-Bigas, MDProfessorDepartment of Surgical OncologyDivision of Surgery The University of Texas MD Anderson Cancer Center Houston, TX

David P. Ryan, MDChief of Hematology/OncologyDepartment of MedicineMassachusetts General HospitalBoston, MA

Riad Salem, MDProfessor of Radiology, Medicine and SurgeryChief, Section of Vascular and Interventional RadiologyVice-Chairman, Image-Guided TherapyDepartment of RadiologyNorthwestern UniversityChicago, IL

John Strickler, MDAssociate Professor of Medicine Department of Medicine Division of Medical OncologyDuke University Medical CenterDurham, NC

Paul H. Sugarbaker, MDDirector, Program in Peritoneal Surface OncologyMedStar Washington Hospital Center Washington, DC


9:00 am Introduction & Welcome Julio Garcia-Aguilar, MD, PhD and Jeffrey Drebin, MD, PhD

9:10 am Stuart Quan Lecture SeriesNancy E. Kemeny, MD

Liver MetastasesCHAIR: Nancy E. Kemeny, MD and Alice Wei, MD

10:00 am Resectable Metastases: Is Neoadjuvant Chemotherapy Necessary?Louise C. Connell, MB

10:15 am The Case of the Disappearing Liver Lesion: Friend or Foe?Alice Wei, MD

10:25 am Resection of Liver Metastasis: Where is the Limit?Aasmund Avdem Fretland, MD

Timing of Resection of Primary and Liver Metastasis

10:40 am SimultaneousWilliam R. Jarnagin, MD

10:50 am StagedYun Shin Chun, MD

11:00 am Panel Discussion

Unresetable Liver Metastasis: Making the Impossible Possible

11:15 am AblationConstantinos T. Sofocleous, MD, PhD

11:25 am Hepatic Arterial Infusion PumpAlice Wei, MD

11:35 am RadioembolizationRiad Salem, MD

11:45 am Molecular Profile-guided TreatmentRona D. Yaeger, MD

11:55 am Panel Discussion

12:15 pm Lunch

Peritoneal MetastasesCHAIRS: Garrett M. Nash, MD, MPH and Andrea Cercek, MD

Appendiceal and Colorectal Cancer

1:00 pm Intraperitoneal Therapy is DeadDavid P. Ryan, MD

1:15 pm Long Live Intraperitoneal TherapyPaul H. Sugarbaker, MD

1:30 pm Minimizing the Morbidity of Maximally Invasive SurgeryBrendan Moran, MD

1:45 pm Panel Discussion

Schedule | Friday, November 8

Low Grade Mucinous Appendiceal Neoplasm

2:00 pm What is This? Efsevia Vakiani, MD

2:10 pm Now What Do I Do? H. Richard Alexander, MD

New Approaches to Peritoneal Metastases

2:20 pm Novel Intraperitoneal TherapiesDavid L. Bartlett, MD

2:30 pm Percutaneous ManagementDavid L. Morris, MD, PhD

2:40 pm Panel DiscussionEfsevia Vakiani, MDH. Richard Alexander, MD David L. Bartlett, MDDavid L. Morris, MD, PhD

3:00 pm Break

Integrating Locoregional and Systemic TherapiesCHAIRS: Constantinos T. Sofocleous, MD, PhD and Rona D. Yaeger, MD

SESSION I: Lung Metastases

3:10 pm Lung Metastasis: ResectBernard J. Park, MD

3:20 pm Lung Metastasis: AblateStephen Solomon, MD

3:30 pm Lung Metastasis: RadiateAndreas Rimner, MD

3:40 pm Lung Metastasis: ProcrastinateAndrea Cercek, MD


SESSION II: Lung Metastases

4:10 pm Resection of Retroperitoneal Lymph Node MetastasesMiguel Rodriguez-Bigas, MD

4:25 pm Radiotherapy: Not Just Palliation for CR Metastases (Liver/RPLNs)Christopher Crane, MD

4:40 pm Chemtherapy for Stage IV Disease: Blurring the LinesLeonard Saltz, MD

4:55 pm Who Benefits from Immunotherapy?Karuna Ganesh


5:30 pm Adjourn

Schedule | Saturday, November 9


Management of the Primary Tumor in Synchronous Stage IV DiseaseCHAIRS: Miguel Rodriguez-Bigas, MD and Christopher Crane, MD

8:00 am ColonGeorge J. Chang, MD

8:15 am RectumMartin R. Weiser, MD

8:30 am Case Presentations and DiscussionLeonard Saltz, MDChristopher Crane, MDPhilip B. Paty, MDJulio Garcia-Aguilar, MD, PhDBrian Bednarski, MD

What’s New in Colorectal/Appendiceal Cancer: Results of Clinical TrialsCHAIR: Luis A. Diaz, MD

9:00 am Prodige 7: HIPEC for mCRCFrancois Quenet, MD

9:20 am ICARuS: Intraperitoneal Chemotherapy After cytoReductive SurgeryGarrett M. Nash, MD, MPH

9:40 am BEACON: BRAF Mutant mCRCRona D. Yaeger, MD

10:00 am First Line Immunotherapy for dMMR CRCDung Le, MD

10:20 am Mountaineer: HER2 inhibition for mCRCJohn Strickler, MD

10:40 am Break

Tumor Board Metastatic Colorectal/Appendiceal CancerCHAIRS: Julio Garcia-Aguilar, MD, PhD and Maria Widmar, MD, MPH

10:50 am PANELISTS

Rona D. Yaeger, MDYun Shin Chun, MDAasmund Avdem Fretland, MDMarc J. Gollub, MDFrancois Quenet, MD

Leonard Saltz, MDEfsevia Vakiani, MDJohn Strickler, MDMiguel Rodriguez-Bigas, MD

12:30 pm Adjourn


Registration Fees Day 1 Only (Thurs.)

Day 2-3 Only (Fri.-Sat.)

Both Symposiums (Thurs.-Sat.)

Physicians (MDs, PhDs and DOs) $200 $400 $500

Residents, Fellows & Other Healthcare Professionals $150 $300 $350

Industry Members* $475 $950 $1,325

*Industry professionals may attend MSK CME activities for their own education. Marketing, sales, and promotion of products and services is strictly prohibited at MSK CME activities.

Register online:

mskcc.org/colorectalcourseCourse registration includes continental breakfast, lunch, and refreshment breaks. Please contact [email protected] at least one week prior to the course if you have any special dietary requests or require any specific accommodations.

• MSK CME offers a discounted rate for MSK Alumni, MSK Cancer Alliance and Cancer Care Partners. If you are a member of one of these groups, please contact [email protected] for more information.

• MSK employee registration is complimentary. However, you must complete course registration in order to attend this course.

Registration

Course Location Memorial Sloan Kettering Cancer Center Zuckerman Research Center 417 East 68th StreetNew York, NY

AccommodationsMSK has negotiated special rates and amenities at select hotels in Manhattan. For information on hotels in the vicinity of MSK with discounted rates, visit: mskcc.org/cme

ContactMemorial Sloan Kettering Cancer CenterOffice of Continuing Medical Educationmskcc.org/[email protected]

Accreditation StatementMemorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

AMA Credit Designation StatementMemorial Sloan Kettering Cancer Center designates this live activity for a maximum of 19.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Faculty DisclosureIt is the policy of MSK to make every effort to insure balance, independence, objectivity, and scientific rigor in all continuing medical education activities which it provides as an ACCME accredited provider. In accordance with ACCME guidelines and standards, all faculty participating in an activity provided by MSK are expected to disclose any significant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services which are discussed by the faculty members in an educational presentation. As required by the ACCME, when an unlabeled use of a commercial product or an investigational use not yet approved for any purpose is discussed during an educational activity, MSK requires the speaker to disclose that the product is not labeled for the use under discussion or that the product is still investigational.

Accreditation


4th Annual Advances in Colorectal Oncologyin the management of advanced colorectal cancer. 2) Increase the learner’s ability to integrate the various aspects of metastatic colorectal

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