داتعلاا ميلعتلا ةدوج åاضل ةيموقلا ةئي ìلا · principles of the metabolism of foreign compounds in mammals. The xenobiotics covered include drugs,

الهيئة القومية لضمان جودة التعليم واالعتماد

University: Alexandria

Faculty: Medicine

Programme Specifications

(Academic year: 2015/2016 )

A. Basic Information:

1. Program title: Doctorate Degree of Medical Biochemistry.

2. Program Award/Degree: Doctorate Degree.

3. Department (s) offering the program; Medical Biochemistry. 4. Program Coordinator: Professor Dr: Sabah Abdel-Hady Mahmoud

5. External evaluator(s): Prof. Dr. Yosry Mostafa

6. Type of the program: Single.

7. Date of most recent program specifications approval: 25/8/2015

B. Professional Information

1- Programme Aims

1.1 Develop updated and advanced knowledge in Medical Biochemistry and Molecular

Biology .

1.2 Prepare the students to be good teachers and efficient researches.

1.3 Apply recent laboratory investigations and recent researches in Medical Biochemistry

and molecular genetics.

2- Acdemic reference standards (ARS) & Subject benchmark statements:

Academic reference standards of Doctorate Degree in Medical Biochemistry and

Molecular biology designed and approved by Department of Medical Biochemistry .

Faculty of Medicine. Alexandria University. Based on:

Generic Academic Reference Standards (ARS): Postgraduate Medical Education, Egypt

(2009). Published by National Authority for Quality Assurance and Accreditation of

Education (NAQAAE) National

[http://naqaae.org/main/php/book/index.php]

.

Domain

Core Competencies

Ilos

A. Knowledge and

Understanding

Graduate of this

program must develop

extensive and perfect

knowledge and

understanding of:

Different metabolic

processes in the body.

A1. Revise and upgrade

their knowledge about the

metabolism and function

of different food stuffs in

the body.

A2. Discuss the advanced

knowledge about

metabolism of

macromolecules and

different tissues and its

relation to their function.


A3. Discuss the different

processes for xenobiotic

metabolism and

detoxication

Recent advances in

molecular biology and

cell signaling.

A4. Discuss recent and

advanced information in

molecular biology.

A5. Explain the basic and

advanced mechanisms of

cell signaling and

neurotransmitters.

B- Intellectual Skills Interpret, evaluate and

apply information from

different resources.

B1. Analyze different

information and its use in

problem solving.

B2. Review recent

publications in the field of

medical biochemistry and

molecular biology

Correlate and interpret

the results of different

laboratory tests and

clinical conditions.

B3. Improve different

laboratory methods for

better diagnosis of

diseases on molecular

basis.

B4. Implement the recent

information in

biochemistry in the

biochemistry and

molecular biology lab.

Modify and create

research methods

B5. Prepare good research

projects.

B6. Create better methods

for better diagnosis and

treatment of diseases.

Critically appraise

published relevant

literature.

B7. Critically appraise and

evaluate different papers

and research methods.

B8. Adopt the ability for

writing of good papers.

B9. Choose the correct

scientific information

from different papers

C. Professional Skills Perfect all laboratory C1. Apply perfectly basic


methods in medical

biochemistry and

molecular biology.

techniques used in clinical

biochemistry.

C2. Perform efficiently

the molecular biology

techniques for diagnosis

of congenital diseases.

Use and choose the

methods in

biochemistry and

molecular biology

efficiently for better

diagnosis of diseases

C3. Apply alternative

methods and procedures if

ideal lab facilities are not

present.

C4. Write and publish

scientific papers.

C5. Explain scientific

information to students

and peers.

D. General and

transferable skills Leads and co-operate

with colleagues and

seniors.

D1. Working in multi-

professional team.

D2. Lead a working team.

Adopt good teaching

methods

D3. Develop efficient

writing and presentation

skills.

Obtain and collect data

from multiple sources

D4. Develop the

capability of retrieving

scientific information and

evaluate different data.

E. Ethics and Attitudes Teach and implement

ethical regulations in his

professional and

practical practices

E1. Follow ethical rules in

research and laboratory

techniques

E2. Promote good

relations with seniors,

colleagues and students.

E3. Apply concepts of

sterilization and infection

control in laboratory.

E4. Behave as a good

example for students and

junior staff

Program courses ILOs Matrix


ILOs Course title

A1

A2

A3

A4

A5

B1

B2

B3

B4

B5

B6

B7

B8

C1

C2

C3

C4

C5

D1

D2

D3

D 4

E1

E2

E3

E4

Biochemistry of Nutrition

X X X X X X X X X

Cell Membrane and Transport

X X X

Laboratory Methods and their Utilization in Biochemistry

X X X X X X X X X X X X X X X

Advanced course in Metabolism of Macromolecules

X X X

X X X X X X

Clinical Chemistry

X X X X X

Medical Problem Solving in Biochemistry

X X X X X X

Lab Rotations

X X X X X X X X

Molecular Biology II

X X X X X X X X X X X

Metabolism of Xenobiotics and ROS


Cell Signaling

X X X X X X X X X


and Neurotransmitters

Biochemistry of the Major Metabolic Diseases

and Aging


Project in Biochemi

stry

X X X X X X X X X X X X X X

Lab Management

X X X X X X X X

Seminar and Journal Club II

X X X X X X

1. Curriculum Structure and Contents:

5.1 Program duration: 3- 7 years

5.2 Program structure: Students should fulfill a total of 52 Credit hours Obligatory subjects: 30 Credit Hours. Thesis: 20 Credit Hours. 2 Elective Subjects: 1 Credit Hour Each.

Program courses:

A. Obligatory:

Code

Number

Credit

Hours Course

Theoretical Practical Prerequisites

05160901 3 Biochemistry of Nutrition 3 0516811

05160902 2 Cell membrane and

transport

2 - ---

05160903 3

Laboratory methods and

their utilization in

Biochemistry

1.5 1.5 0516803,

0516808

05160904 2

Advanced course in

Metabolism of

Macromolecules

2 -

0516809

05160905 3 Clinical Chemistry 2 1 0516811

05160906 1

Medical problem solving

in biochemistry

1 -

0516811


05160907 1 Lab rotations - 1 0516803,

0516808

05160908 3 Molecular biology II 2 1 0516802

05160909 2 Metabolism of

Xenobiotics and ROS

2

0516811

05160910 3 Cell signaling and

neurotransmitters

3 - 0516807

05160911 3

Biochemistry of the major

metabolic diseases and

Aging

-

0516811

05160912 2 Project in Biochemistry - 2 0516803,

0516808

05160913 1 Lab Mangement 1 - -

05160914 1 Seminar II and Joural

Club

1 - -

B. Elective:

Code Number Course Credit hours

050280831 Medical Genetics 1

………. Basic Microbiology 1

05200801 Basic Physiology 2

0560801 Basic Pharmacology 2

05110804 Clinical Toxicology 1

05190802 Diagnostic Parasitology 1

Other -

6 Program Admission Requirements:

According to the regulations of the credit hour bylaws of the Faculty of Medicine

Alexandria University (annex).

7 Regulations for Progression and Program Completion:

According to the regulations of the credit hour bylaws of the Faculty of Medicine

Alexandria University (annex).


8 Methods of student assessment:

Methods Intended Learning outcomes to be

assessed

1. Written Exam

- MCQ (Objective)

- Essay

a1,a2,a3,a4,a5

b1,b2,b3,b4

2. Practical Exam c1,c2,c3,e1,e3,e4

3. Assignment c4,c5,d2,d3,d4

4.Thesis b1- b8, d1,d3,d4

9 Methods of program evaluation:

Evaluator Tool Sample

1. Students enrolled in the program Questionnaires. All

2. Alumni --------

3. Stakeholders (Employers) Focus group

4. External Evaluator (s) -----------

5. Others:

Course Specifications:

Code Credit Hours Course Prerequisites

05160901 3 Biochemistry of

Nutrition

0516811

This course includes identification of macro and micronutrients, recommended

dietary allowances, energy production by different nutrients, integration of different

compounds of intermediary metabolism, alteration in substrate load induced by dietary

modifications, conditions with particular relevance to clinical nutrition, nutrition support

(oral supplementation, tube feedings and parental nutrition), anthropometric

measurements ( body weight, skin fold thickness, endogenous 3- methyl Histidine

excretion, bioelectric impedance analysis) and biochemical measurements e.g. plasma

proteins, nitrogen balance studies. With special emphasis on the role of different vitamins

in the body, vitamin deficiencies and toxicity, vitamin supplement usage in modern

society.



05160902 2 Cell Membrane and

Transport

-

This course includes: the supramolecular architecture of membranes, membrane lipids,

membrane proteins, membrane fusion, solute transport across membranes, ion-selective

channels transport of macromolecules, receptor mediated transport, differentiations at the

cell surface and intercellular communications (microvilli, desmosomes, gap junctions),

coats of the cell membrane and cell recognition, cell-cell recognition and specific cell

adhesion, changes in cell surface properties in cancer cells.


05160903 2

Laboratory Methods

& Their Utilization

in Biochemistry

0516803, 0516808

This course includes: Revision of general metabolism and its regulation. Also, general

principles of biochemical investigations and techniques of centrifugation,

immunochemistry, molecular biology, chromatography, electrophoresis, spectroscopy, and

radiochemistry.


05160905 3 Clinical Chemistry 0516811

This course includes: introduction to medical lab science (functions & responsibilities),

medical lab methods and techniques (electrophoresis, chromatography, spectrophotometry,

radioimmunoassay, etc.), overview of medical lab procedures routinely used to diagnose

common diseases (heart markers, liver function tests, kidney function tests, etc.)

Laboratory applications of the subject.


05160904 2

Advanced Course in

Metabolism of

Macromolecules

0516809

This course includes: the assembly of macromolecules; viruses, collagen fibres,

fibrinogen and thrombin, three levels of organization of proteins, haemoglobin,

isoenzymes and multienzyme complex, assembly of conjugated proteins, assembly of

complex polysaccharides, assembly of informational molecules.



05160909 2

Metabolism of

xenobiotics and

ROS

0516811

This course provides a broad understanding of the physical, biological and chemical

processes involved in pollution of the atmosphere, land and water, causes of pollution and

effect of pollutants on human health. It also includes an advanced study of the basic

principles of the metabolism of foreign compounds in mammals. The xenobiotics covered

include drugs, food additives, and agricultural, chemical and industrial chemicals. The

detoxification and toxicological implications of metabolism are emphasized.


05160906 1

Medical Problem

Solving in

Biochemistry

0516811

Training of the student on interpretation of the clinical and laboratory findings with the

trials to find the biochemical causes behind the problem and answering questions about the

case.


05160907 1 Lab rotations 0516803, 0516808

The student is trained in different medical laboratories in the faculty to get experience

in analytical methods applied in each of them.

Code Credit Hours Course Prerequisite

05160908 3 Molecular Biology II

0516802

This course includes: mutagenesis, oncogenes, heterogeneous gene expression with a

special focus on molecular events which regulate cell cycle transition and their relevance to

human cancer, chemical synthesis of DNA, reverse transcriptase and HIV, transposons and

related retroviruses, concepts of classical genetics (including genetic mapping, extranuclear

inheritance, polypoidy, and evolutionary genetics).

Lab and demonstrations: Manipulation and analysis of genes and genomes, gene

amplification and disease diagnosis, Southern blot and analysis of complex genome structure.



05160912 2 Project in

Biochemistry 0516803, 0516808

This course includes directed laboratory research performed under the supervision of a

faculty member. Each student is required to carry out one detailed study of the scientific

literature related to the subject of the research applied.


05160913 1 Lab management

This course revise the general principles of how to measure the lab precision and

accuracy. Also Discuss the principles of calibration of the instruments , performance and

criteria of the control material.

Code Credit Hours Course Prerequisite

05160910 3 Cell signaling and

neurotransmitters 0516807

This course includes basic concepts of receptors, steroid receptors, G-protein coupled

receptors, receptor regulation of adenyl cyclase, role of cAMP in regulation of cellular

metabolism, cyclic AMP-protein kinase, protein kinase structure and regulation, other second

messengers as calcium and phosphatidyl inositol, How is calcium mobilized as a messenger

and acts to regulate cell function?, growth factors receptors: function and regulation, Tyrosine

kinase receptors, activation of PI 3- kinase signaling, targeting the transcriptional apparatus

via cell signaling, diverse signaling pathways control of transcription, transcriptional control

via cAMP signaling, nuclear receptors: the ligand-activated transcription factors, nuclear

receptors: role of protein-protein interactions in signaling, role of multiprotein

coactivators/corepressors complexes in signaling, overview of apoptosis, death receptors and

mitochondria in apoptosis, NF-kB/IkB system, direct pathways to the nucleus: JAK/STAT

and others, Ras signaling, neurotransmitters and neuromodulators.


05160911 3

Biochemistry of the

Major Metabolic

Diseases and Aging

0516811

This course includes an overview on the metabolic changes in common diseases in the

society as diabetes mellitus, hypertension, atherosclerosis, schestosomiasis, etc. with

special emphasis on metabolic changes of aging.



05169014 1 Seminar II and

Journal Club 0516811, 0516813

This course includes special topics current to the field of biochemistry. Topics and

format for the course may vary. Study presentation is done by each student under

supervision of a faculty member.

Program director: Sabah Abdel-Hady Mahmoud

Signature:

Program coordinator:

Professor Dr: Sabah Abdel-Hady Mahmoud

Signature: Date:

Course Specifications


Faculty: Medicine

Department: Medical Biochemistry

Course Information

Course Code: 05160901 Course Name: Biochemistry of nutrition

Program in which the Course is Given : Doctorate degree of Medical Biochemistry

Number of Credit Hours 3 Clinical/PracticalTheoretical

Course Aims:

1. Identification of macro and micronutrients and their metabolic importance.

2. Implementation of principles of clinical nutrition.

3. Evaluation of anthropometric and biochemical measurements.

Intended Learning Outcomes (ILOs)

Program ILO (refer to program

matrix) Course ILOs

A. Knowledge

and

Understanding

A1. Revise and upgrade their

knowledge about the metabolism

and function of different food stuffs

in the body.

A2. Discuss the advanced knowledge

about metabolism of

macromolecules and different tissues

and its relation to their function.

A3. Relate structure of different vitamin molecules to their function.

a1. Revise the different metabolic

pathways of different food stuffs and

their functions in the body.

a2. Discuss energy production by

different food stuffs.

a3. Discuss the different functions of

macromolecules and their

metabolism in different tissues.

a4. Determine recommended dietary

allowances of different food stuffs

and macromolecules.

a5. Discuss the advanced knowledge

about metabolism of vitamins in

different tissues and its relation to

their functions

B. Intellectual

skills

B1. Interpret, evaluate and apply

information from different

resources.

b1. Integrate different metabolic pathways

in the body.

b2. Apply the information in clinical

nutrition and dietary modifications.

- 3

B2. Review recent publications in

the field of medical biochemistry

and molecular biology.

b3. Deduce manifestations and causes of

deficiency of deferent vitamins.

b4. Analyze the manifestations of

deficiency of vitamins A, D, E, K in

relation to their functions.

b5. Analyze different anthropometric and

biochemical measurements.

b6. Use recent information for better

nutritional states.

C.Professional

and Practical

Skills

D. General

Skills

D1. Work in multi- professional team.


D3. Develop efficient writing and

presentation skills.

D4. Capable of retrieving scientific

information and evaluate different

data.

d1. Cooperate with her/his colleagues in

preparing work plans.

d2. Acquire the capacity of Leading a

working team.

d3. present a scientific presentation.

d4. Collect and analyze scientific data.

Course Content (Units/Topics)

Teaching/Learning Methods

Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes:

Identification of macro and

micronutrients, recommended dietary

allowances, energy production by

different nutrients, integration of

different compounds of intermediary

metabolism, alteration in substrate

load induced by dietary modifications,

conditions with particular relevance to

clinical nutrition, nutrition support (oral

supplementation, tube feedings and

parental nutrition), anthropometric

measurements ( body weight, skin fold

thickness, endogenous 3- methyl

Histidine excretion, bioelectric

impedance analysis) and biochemical

measurements e.g. plasma proteins,

nitrogen balance studies.

√ √ - √ √

Please check (✓) the appropriate method.

Student Assessment

Methods of Assessment

Essay Objective questions

Case OSCE/OSPE

Assignment Logbook fulfillment

Others

Schedule of Assessment

Mid-term

End of term 100 %

Distribution of Marks

Written Exam 80 %

Practical/Clinical Exam -

Others 20 %

√ √

√

✓

List of Textbooks and References

Lecture Notes

Course Text Books

1- Biochemistry. Stryer

2- Lehninger Biochemistry

3- Molecular cell Biology. Lodish

Suggested Extra Reading

1- Recent publications

2- Any specialized text books

Journals and Periodicals, others

Relevant journals

Course Instructor

Name: Pr. Dr. Soad El- Tabakh Signature:

Program Coordinator

Name: Prof. Dr. Sabah Abdel-Hady Mahmoud Signature:

Program Director (Head of Department)

Name: Prof. Dr. Sabah Abdel-Hady Mahmoud Signature:



Faculty: Medicine


Course Information

Course Code: 05160902 Course Name: cell membrane and transport

Program in which the Course is Given: Doctorate Degree of Medical Biochemistry.

Number of Credit Hours: 2 Clinical/PracticalTheoretical

Course Aims: The student in this course should

1. Develop updated and advanced knowledge in supramolecular architecture of membranes

and changes in cell surface properties in cancer cells.

2. Prepared to be efficient researches.



matrix) Course ILOs

A. Knowledge

and

Understanding


knowledge about metabolism of

macromolecules and different

tissues and its relation to their

function.

a1. Discuss advanced knowledge about

the supramolecular architectur of

membranes, membrane lipids,

membrane proteins, and membrane

fusion.

a2. Describe solute transport across

membranes,

a3. Illustrate ion-selective channels

transport of macromolecules, and

receptor mediated transport.

a4. Describe differentiations at the cell

surface and intercellular

communications (microvilli,

desmosomes, gap junctions).

a5. Describe cell recognition, cell-cell

recognition and specific cell

adhesion

_ 2

D.

General Skills

D4. Develop the capability of

retrieving scientific information

and evaluate different data.

d1. Critically appraise and

evaluate different papers and

researches relevant to cell

membrane and transport.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes basic

knowledge about the supramolecular

architecture of membranes,

membrane lipids, membrane

proteins, membrane fusion, solute

transport across membranes, ion-

selective channels transport of

macromolecules, receptor mediated

transport, differentiations at the cell

surface and intercellular

communications (microvilli,

desmosomes, gap junctions), and

cell recognition, cell-cell recognition

and specific cell adhesion, changes

in cell surface properties in cancer

cells.

✓ ✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term -

End of term 100 %


Written Exam 80 %


Others 20 %


Lecture Notes

-

Course Text Books

1. Lehninger Biochemistry

2. Molecular cell Biology Lodish


1. Recent publications

2. Any specialized text books


Relevant journals

Course Instructor

Name: Prof. Dr: Samia AbdelFatah Sharaf Signature:

Program Coordinator

Name: Prof. Dr: Sabah Abdel-Hady Mahmoud Signature:


Name: Prof.Dr: Sabah Abdel-Hady Mahmoud Signature:

✓ ✓

✓ ✓

✓



Faculty: Medicine


Course Information

Course Code: 05160903 Course Name: Laboratory Methods & Their

Utilization in Biochemistry

Program in which the Course is Given: Doctorate program of Medical Biochemistry

Number of Credit Hours 3 Theoretical Clinical/Practical

Course Aims:

1. Identify the components of the scientific method and explain each.

2. Perform and evaluate scientific experiments.

3. Design scientific experiments.

4. Upgrade integrated knowledge in metabolism and molecular biology.

5. Interpret the molecular basis of metabolic disorders.



matrix) Course ILOs

A. Knowledge

and

Understanding



and function of different food

stuffs in the body.

a1. Revise general metabolism

a2. Discuss the principles of regulation

of metabolism

a3. Revise the general principles of

biochemical investigations

a4. Discuss the principle of different

laboratory techniques.

B. Intellectual

skills



and molecular biology

B3. Improve different laboratory

methods for better diagnosis of

diseases on molecular basis.

b1. Explain the metabolic behavior of

the body in different situations

b2. Relate the metabolism of different

tissues to each other’s

b3. Interpret the biochemical disorders

according to molecular basis

b4. Evaluate different laboratory

methods in respect of accuracy,

sensitivity and specificity.

1.5 1.5


information in biochemistry in the

biochemistry and molecular

biology lab.



research methods.

b5. Compare the utility of different

laboratory methods in specific item

estimation.

b6. Modify the existing laboratory

techniques.

b7. Design scientific experiments

b8. Review and critically appraise recent

publications in the field of laboratory

methodology.

C.

Professional

and Practical

Skills

C1. Apply perfectly basic


biochemistry.

C2. Perform efficiently the

molecular biology techniques for

diagnosis

C3. Apply the accumulated

integrated knowledge to daily life.

C.4 Upgrade practical skills in


biology

C5. Apply alternative methods and

procedures if ideal lab facilities are

not present.

c1. Practice and perfect different

laboratory methods.

c2. Perfect the molecular biology

techniques for diagnosis of diseases.

c3. Use and choose the methods in

biochemistry and molecular biology

efficiently for better diagnosis of

diseases.

D. General

Skills





presentation skills

d1. Collect scientific information and


d2. Acquire the capacity of writing

scientific papers and presentation

skills.

E. Ethics &

Attitude


research and laboratory techniques

E2. Promote good relations with

seniors, colleagues and students

E3. Apply concepts of sterilization

and infection

e1 Follow ethical rules in research and

laboratory techniques

e2 Create good relations with all junior

and senior staffs.

e3 Follow sterilization and anti-

infection roles.

Course Content

(Units/Topics)


Lectures

self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment


general principles of

biochemical

investigations and

techniques of

centrifugation,

immunochemistry,

molecular biology,

chromatography,

electrophoresis,

spectroscopy, and

radiochemistry.

✓

✓ ✓ ✓


Student Assessment



Case OSCE/OSPE

Assignment 10%

Logbook fulfillment

Others


Mid-term(Written & practical) 20%

Practical 20%

End of term 50%


Written Exam 70%

Practical/Clinical Exam 20%

Others 10%


Lecture Notes

-

Course Text Books

• Biochemistry by Lubert Stryer

• Harper’s Biochemistry

• Devlin

• Clinical Chemistry

• Fundamentals of clinical

Chemistry. Tietz

• Varley. Biochemical methods


- Any related recent text book


- Relevant journals & periodicals

Course Instructor:


Name: Prof. Dr. Gihan Mohamed Sharara Signature:

Program Coordinator




✓

✓

0

%

3

0

%

0

✓



Faculty: Medicine


Course Information

Course Code: 05160904 Course Name: Advanced Course in Metabolism

of Macromolecules

Program in which the Course is Given

Number of Credit Hours 2 Clinical/PracticalTheoretical

Course Aims:

Graduate of this program must :

1- Develop updated and advanced knowledge about metabolism of macromolecules at different

tissues.

2- Relate structure of different macromolecules to their function.

3- Correlate abnormal structure-function relationship of these molecules to metabolic diseases.



matrix) Course ILOs

A. Knowledge

and

Understanding




stuffs in the body.

a1. Revise different metabolic pathways

in human body.

a2. Describe high order structure of

different globular proteins as

hemoglobin & enzymes.

a3. Discuss how the structure of these

molecules can affect their function.

a4. Explain role of fibrous &

specialized proteins and

proteoglycans of extra cellular

matrix in many normal and

pathologic processes.

-- 2





function.

a5. Discuss genetic, physiologic and

pathologic aspects of glycomics;

glycoproteins, proteoglycan &

glycolipids.

B. Intellectual

skills

B1. Analyze different information

and its use in problem solving.






research methods.


methods specific for each metabolic

disease.

b2. Select different papers and research

methods.

b3. Evaluate and solve problem

situations related to metabolic

diseases.

b4. Review and critically appraise

recent publications in the field of

macromolecules biology and

pathology.

C.Professional

and Practical

Skills

C3. Apply alternative methods

and procedures if ideal lab

facilities are not present.

C4. Implement knowledge about

signaling in researches e.g. to

target a signal pathway in


c1. Use and choose efficient methods for

better diagnosis of diseases.

c2. Link knowledge about biology to

molecular markers for detection and to

prospective lines of treatment.

D. General

Skills

E. Ethics &

Attitude








techniques.


seniors, colleagues and students.

d1. Acquire the capability of retrieving

scientific information and evaluate

different data.

d2. Develop efficient writing and


e1. Follow ethical rules in research.

e2. Promote good relations with

seniors, colleagues and student.



Lectures

self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes: the

assembly of macromolecules;

collagen fibres, fibrinogen and

thrombin, three levels of

organization of proteins,

haemoglobin, isoenzymes and

multienzyme complex,

assembly of conjugated

proteins, assembly of complex

polysaccharides, assembly of

informational molecules.

This course involves the

structure- function relationships

of different macromolecules and

✓ ✓ ✓ ✓

biomedical implications. It

includes

- High ordered structure

of globular proteins as

hemoglobin and

enzymes & molecular

basis of genetic diseases.

- Mechanism of action of

enzymes and

multienzyme complexes.

- Fibrous ( collagen,

elastin, fibrillin,..) &

specialized proteins

(fibronectin, laminin,…)

and proteoglycans (

GAGs as heparin,..) of

extra cellular matrix in

many normal and

pathologic processes

(development, aging,

inflammation, cancer

spread,…..).

- Glycoproteins;

assembly, degradation,

and role in biologic

processes (fertilization,

cell adhesion,

inflammation,..) &

genetic diseases (I-

disease, …), other

diseases (viral, HIV,

RA,..).


Student Assessment



Case OSCE/OSPE


Others


Mid-term(Written & practical) -

End of term 100 %


Written Exam 80 %

Practical/Clinical Exam 0 %

Others 20 %


Lecture Notes

-

Course Text Books

1. Harper’s illustrated Biochemistry.

2. Devlin’s textbook of Biochemistry.

3. Lehninger Biochemistry.

4. Stryer’s Biochemistry.


- Any related recent text book.


- Relevant journals & periodicals.

Course Instructor:

Name: Professor Dr: Hanan Kamal AbdelAziz Signature:

Program Coordinator




✓

✓

✓



Faculty: Medicine


Course Information

Course Code: 05160905 Course Name: Clinical Chemistry

Program in which the Course is Given within the courses assigned to the doctorate degree of

medical Biochemistry


Course Aims: The student in this course must

1. Develop updated and advanced knowledge in medical lab science and Laboratory applications.

1.2 Prepare the students to be efficient researches.

1.3 Apply recent laboratory investigations and recent researches in Medical Biochemistry and

molecular genetics.



matrix) Course ILOs

A. Knowledge

and

Understanding



and function of different organs in

the body.

a1. Revise the general principles of

biochemical investigations

a2. Discuss the principle of different

laboratory techniques

a3. Interpret the diagnostic, specific tests

used in the clinical chemistry field.

B. Intellectual

skills






b1. Interpret, evaluate and apply

information from different resources.

b2. Critically appraise published relevant

literature

1 2

C.Professional

and Practical

Skills



biochemistry.

c1. Practice and perform different

laboratory methods.

c2. Determine the methods in


efficiently for better diagnosis of

diseases

D. General

Skills

D1. Working in multi- professional

team.

d1. Working in the team clinical chemistry lab.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes: introduction to

medical lab science (functions &

responsibilities), medical lab methods

and techniques (electrophoresis,

chromatography, spectrophotometry,

radioimmunoassay, etc.), overview of

medical lab procedures routinely used

to diagnose common diseases (heart

markers, liver function tests, kidney

function tests, etc. Laboratory

applications of the subject.

✓ ✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term 20 %

End of term 80 %%


Written Exam 70 %

Practical/Clinical Exam 20 -

Others 10 %


Lecture Notes

Course Text Books

• Clinical Chemistry

• Fundamentals of clinical

Chemistry. Titz

• Varley. Biochemical methods


Any related recent text book


Relevant journals & periodicals

Course Instructor

Name: Dr: Fayrouz El-Sayed Signature:

Program Coordinator




✓ ✓

✓

✓



Faculty: Medicine


Course Information

Course Code: 05160906

Course Name: Medical Problem Solving in

Biochemistry

Program in which the Course is Given: Doctorate Degree of Medical Biochemistry

Number of Credit Hours 1 lClinical/PracticaTheoretical

Course Aims: helping students learn and critical thinking by training them on interpretation of the

clinical and laboratory findings.



matrix) Course ILOs

A. Knowledge

and

Understanding

B. Intellectual

skills



b1. Be exposed to multiple

examples of biochemical

health problems.

b2. Acquire the ability to use

available lab results and

information to solve health

problems.

b3. Formulate and solve

biochemical problems of

clinical interest.

b4. Integrate different parts of

biochemistry with clinical

situations.

- 1






research methods.

B8. Adopt the ability for writing of

good papers.

b5. Use recent publications and

text books in reaching to

interpret and predict solutions

to biochemical problems.

b6. Collect, evaluate, correlate

and interpret the biochemical

data to reach a final

conclusion that lead to

diagnosis and treatment.

b7. Acquire the ability of writing

a scientific report and papers

in relation to biochemical

health problems

C.Professional

and Practical

Skills

C5. Explain scientific information

to students and peers.

c1. Prepare exercise in

biochemical health problems

c2. Explain the plan leading to

solving of the biochemical

problem.

D. General

Skills

D1. d2. Lead a working team.

d1. Guide a team through a health

problem process

d2. Survey and accept and discuss

the team members opinions



Lectures self learning Practical/

Clinical

Small

group

discussion

Others

Assignment


training of the student on

interpretation of the clinical and

laboratory findings with the

trials to find the biochemical

causes behind the problem and

answering questions about the

case.

✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term 40 %

End of term 60%


Written Exam 70%


Others 30%

✓ ✓

✓

✓


Lecture Notes

-

Course Text Books

- Biochemistry, Case Oriented

Approach.

-


- Devlin. Biochemistry


- Clinical chemistry

Course Instructor:

Name: Prof. Dr: Fayrouz El-Sayed Signature:

Program Coordinator






Faculty: Medicine


Course Information

Course Code: 05160907 Course Name: Lab rotations

Program in which the Course is Given: Doctorate degree of Medical Biochemistry

Number of Credit Hours Theoretical Clinical/Practical

Course Aims:

1. Develop updated and advanced knowledge in different medical laboratories of different

specialties.

2. Prepare the students to be efficient researches.

3. Apply recent laboratory investigations and recent researches in Medical Biochemistry and

molecular genetics.

Training of students in



matrix) Course ILOs

A. Knowledge

and

Understanding

B. Intellectual

skills

B1 Utilize different diagnostic

assays effectively.

B2 Choose better practical

methods for better

diagnosis of diseases.

b1. Use alternative diagnostic methods.

b2. Apply the suitable diagnostic assays

according to the current situation.

1 -

C.Professional

and Practical

Skills



biochemistry (elisa,

immunodiffusion, enzyme

activity assay, colorimetric

methods and others).

c1. Perfect the basic lab techniques

(ELISA, immunodiffusion, enzyme

activity assay and colorimetric

methods

c2. Apply lab safety roles in the labs

she/he responsible for.

D. General

Skills

D2. Co-operate efficiently in a

multi-professional team

working.

D3. Recognize and respect the

views and opinions of other team

members.

D4. Use information technology

to access, evaluate, and interpret

scientific data.

d1. Acquire the capacity of working in a

team.

d2. Respect the views and opinions of

other team members.

d3. Interpret scientific data.

E. Ethics and

Attitudes

E1. Promote high standards of

personal and organizational

integrity, compassion,

honesty, and respect for

seniors, colleagues,

assistants, and students.

E2. Deal with reagents,

instruments, and

equipments with caution

and preservation.

e1. Be a good example for assistants,

and students.

e2. Implement the regular roles of

dealing with reagents and

instruments.

e3. Be accurate in analyzing the results

and avoid fabrication.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

The student is trained in different

medical laboratories in the faculty to get

experience in analytical methods

applied in each of them

✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term 0%

End of term 100%%


Written Exam %


Others 10%


Lecture Notes

-

Course Text Books

Clinical Chemistry



Course Instructor

Name: Professor. Dr. Ehsan Mohamed AbdelRahman Signature:

Program Coordinator




✓

✓



Faculty: Medicine


Course Information

Course Code: 05160908 Course Name: Molecular Biology II

Program in which the Course is Given


Course Aims:

To help Graduate to

1. Develop updated and advanced knowledge in Molecular Biology .

2. Prepare the students to perfect laboratory methods in molecular biology and efficient researches

3. Apply recent laboratory investigations and recent researches in Medical Biochemistry and

molecular genetics.



matrix) Course ILOs

A. Knowledge

and

Understanding

A4. Discuss recent and advanced

information in molecular biology.

a1. Revise

- Principles of heredity.

- The components of gene expression.

2. Relate structure of nucleic acids to

their function.

a2. Discuss different regulators of gene

expression in both prokaryotes and

eukaryotes.

a3. Describe regulators of cell cycle &

apoptosis.

a4. Explain mechanisms of oncogenesis.

1 2

B. Intellectual

skills








research methods.



sensitivity and specificity for each

genetic disease.

b2. Combine different methods for

better diagnosis of genetic diseases.

b3. Select different papers and research

methods.

b4. Evaluate and solve problem

situations related to genetic diseases.

b5. Correlate defects in gene expression

& repair to carcinogenesis.

b6. Review and critically appraise recent

publications in the field of molecular

biology.

C.Professional

and Practical

Skills



diagnosis of congenital diseases.

C3. Apply alternative methods

and procedures if ideal lab


c1. Perfect the molecular

biology techniques for

diagnosis.

c2. Use and choose the methods

in molecular biology

efficiently for better


c3. Link knowledge about

cancer biology to molecular

markers for detection and to

prospective lines of

treatment.

D. General

Skills

E. Ethics &

Attitude








techniques.




sterilization and infection control

in laboratory.

d1. Acquire the capacity of using

scientific information for writing

scientific papers.

d2. Retrieving and evaluate different

data.

e1 Keep confidentiality in research and

laboratory.

e2 Promote good relations with all the

staff she/he working with

e3 Apply strict sterilization and anti-

infection procedures.

e4 Be accurate in analyzing the results

and avoid fabrication.



Lectures

self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment


mutagenesis, oncogenes,

heterogeneous gene expression

with a special focus on

molecular events which regulate

cell cycle transition and their

relevance to human cancer,

chemical synthesis of DNA,

reverse transcriptase and HIV,

transposons and related

retroviruses, concepts of

classical genetics (including

genetic mapping, extranuclear

inheritance, polypoidy, and

evolutionary genetics).

Lab and demonstrations:

Manipulation and analysis of

genes and genomes, gene

amplification and disease

diagnosis, Southern blot and

analysis of complex genome

structure.

✓ ✓

✓ ✓ ✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others

✓

✓

✓ ✓

✓


Mid-term(Written & practical) 40%

End of term 60%


Written Exam 70%


Others 10%


Lecture Notes

-

Course Text Books

1. Harper’s illustrated Biochemistry.

2. Devlin’s textbook of Biochemistry.

3. Lehninger Biochemistry.

4. Molecular cell biology. Lodish


- Any related recent text book.


- Relevant journals & periodicals.

Course Instructor:

Name: Professor Dr: Eman Ahmed Shaat. Signature:

Program Coordinator



Name: Prof.Dr: Sabah Abdel Hady Signature:



Faculty: Medicine


Course Information

Course Code: 05160909 Course Name: Metabolism of xenobiotics and

ROS



Course Aims: The students should:

1. Develop updated and advanced knowledge in- Physical, biological and chemical processes

involved in pollution of the atmosphere, land and water

2. Apply recent laboratory investigations and recent researches in the field of pollution and

metabolism of xenobiotics

3. Know the classification of free radical, oxidants, sources and metabolism of each,

antioxidant mechanisms and abnormalities caused by alteration of the balance between

oxidants and antioxidants.



matrix) Course ILOs

A. Knowledge

and

Understanding

A1. Discuss the different

processes for xenobiotic

metabolism and detoxication




stuffs in the body.





function.

a1. Discuss basic metabolism of foreign

compounds in the body.

a2. List different sources of pollution.

a3. Describe detoxication process in the

body.

a4. Revise classification of oxidants

a5. Discuss the sources of oxidants in the

body

a6. Explain the effects of each of these

molecules in the body.

a7. Discuss the metabolism of oxidants.

a8. Explain the role of natural

antioxidant molecules

2

B. Intellectual

skills








research methods.


good papers.

b1. Choose better information for

problem solving.

b2. Review recent publications in

metabolism of different drugs and

foreign substances in the body.

b3. Evaluate information in different

papers and research methods.

b4. Acquire the ability to write scientific

papers.

C.Professional

and Practical

Skills



biochemistry.

c1. Adopt the ability to do basic

techniques in clinical chemistry

perfectly

D. General

and

Transferrable

Skills




d1. Adopt efficient leadership skills.

d2. Acquire the ability for efficient

writing and presentation skills.

E. Ethics and

Attitudes



techniques.

E4. Behave as a good example for

students and junior staff.

e1. Adopt the ethical rules in research and

laboratory techniques.

e4. Behave as a good example for students

and junior staff

Course Content

(Units/Topics)


Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course provides a

broad understanding of the

physical, biological and

chemical processes involved in

pollution of the atmosphere,

land and water, causes of

pollution and effect of

pollutants on human health. It

also includes an advanced study

of the basic principles of the

metabolism of foreign

compounds in mammals. The

xenobiotics covered include

drugs, food additives, and

agricultural, chemical and

industrial chemicals. The

detoxification and toxicological

implications of metabolism are

emphasized.Classification of

free radicals oxidants, sources

and metabolism of each,

antioxidant mechanisms and

abnormalities caused by

alteration of the balance

between oxidants and

antioxidants.

√ √ √ √ √


Student Assessment



Case OSCE/OSPE


Others


End of term 100 %


Written Exam 70 %

Assignment 20 %

Others 10 %


Lecture Notes

Course Text Books

1. Clinical Chemistry

2. Lehninger Biochemistry

3. Harper’s Biochemistry


Fundamentals of clinical Chemistry. Titz


Relevant journals in Xenobiotic

metabolism ,free radical and antioxidants

Course Instructor

Name: Pr. Safaa Hussein Mohy el Dine Abou Dia Signature:

Program Coordinator


Program Director


√ √

√

√ √



Faculty: Medicine


Course Information

Course Code: 05160910 Course Name: Cell signaling and

neurotransmitters




Course Aims: the students must get deep and advanced knowledge and implementation of:

1. concepts of receptors and their second messengers.

2. cell to cell signaling

3. growth factors' receptors: function and regulation.

4. diverse signaling pathways.

5. apoptosis, death receptors and role of mitochondria in apoptosis.

6. neurotransmitters and neuromodulators.



matrix) Course ILOs

A. Knowledge

and

Understanding

A5. Explain the basic and advanced

mechanisms of cell signaling and

neurotransmitters.

a1. Revise

- basic concepts of receptors,

- definitions of kinases and

phophatases and their role in signal

transduction

- general mechanisms for signal

transduction across membranes of

any cell that must respond to its

environment

a2. Describe the role of G proteins in

coupling ligand induced

conformational changes

a3. Discuss receptor regulation.

- 3

B. Intellectual

skills

B1. Analyze different information and

its use in problem solving.

B2. Review recent publications in the

field of medical biochemistry and

molecular biology

B7. Critically appraise and evaluate

different papers and research

methods.

b1. Differentiate between kinases

activated by second messengers

and those activated by primary

messengers (ligand-gated

receptor Tyr kinases)

b2. Correlate the neuron responses

mediated by neurotransmitters

and binding gated receptor/ion

channels compares and G-protein

coupled receptors.

b3. Analyze the different causes

leading to apoptosis, death

receptors and mitochondria in

apoptosis

b4. Draw a diagrams showing the

general features of signal

transduction e.g. kinases

mediated signal transduction

pathways that lead to activation

of gene expression, /STAT, Ras

signaling and others. b5. Explain the bound receptor

activation of specific effector

proteins.

b6. Link different cell signaling to

carcinogenesis pathways.

b7. Evaluate different papers and

researches relevant to cell

signaling.

C.Professional

and Practical

Skills

C4. Develop the capability of

retrieving scientific information and


c1. Implement knowledge about

signaling in researches e.g. to



D. General

Skills




retrieving scientific information and


d1 Aquire efficient presentation skills.

d2 Collec scientific information and


E. Ethics and

Attitudes E2. Promote good relations with



students and junior staff

1. Create good working atmosphere with


2. Act as a good example for students and

junior staff and all assistants.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes basic

concepts of receptors, steroid

receptors, G-protein coupled

receptors, receptor regulation of

adenyl cyclase, role of cAMP in

regulation of cellular metabolism,

cyclic AMP-protein kinase, protein

kinase structure and regulation, other

second messengers as calcium and

phosphatidyl inositol, How is

calcium mobilized as a messenger

and acts to regulate cell function?,

growth factors receptors: function

and regulation, Tyrosine kinase

receptors, activation of PI 3- kinase

signaling, targeting the

transcriptional apparatus via cell

signaling, diverse signaling

pathways control of transcription,

transcriptional control via cAMP

signaling, nuclear receptors: the

ligand-activated transcription

factors, nuclear receptors: role of

✓ ✓ ✓ ✓

protein-protein interactions in

signaling, role of multiprotein

coactivators/corepressors complexes

in signaling, overview of apoptosis,

death receptors and mitochondria in

apoptosis, NF-kB/IkB system, direct

pathways to the nucleus: JAK/STAT

and others, Ras signaling,

neurotransmitters and

neuromodulators.


Student Assessment



Case OSCE/OSPE


Others


Mid-term 30%

End of term 70%%


Written Exam 70%


Others 30%

✓ ✓

✓ ✓

✓


Lecture Notes

-

Course Text Books

• Biochemistry. Stryer

• Lehninger Biochemistry

• Molecular cell Biology. Lodish


• Recent publications

• Any specialized text books


Relevant journals

Course Instructor


Program Coordinator






Faculty: Medicine


Course Information

Course Code: 05160911 Course Name: Biochemistry of the Major

Metabolic Diseases and Aging




Course Aims: the students must:

1. Develop updated and advanced knowledge in metabolic changes in common diseases in the

society as diabetes mellitus, hypertension, atherosclerosis, schestosomiasis.

Special emphasis on metabolic changes of aging. 2. Prepare the students to be good teachers and efficient researches.



matrix) Course ILOs

A. Knowledge

and

Understanding




stuffs in the body.





function.

a1. Revise basic concepts of metabolic

diseases. E.g. Diabetes mellitus

a2. Discuss metabolic changes in:

- Diabetes mellitus.

- Atherosclerosis.

- Aging

a3. Explain different tissue affection in

aging. E.g

- muscloskletal system

- Cardiovascular system.

- Endocrine

3

B. Intellectual

skills








research methods.


good papers.

b1. Interpret the clinical and

biochemical data in different

metabolic diseases.

b2. Review recent publications in

the field of diabetes mellitus,

atherosclerosis, aging ,….

Etc

b3. Evaluate different papers and

research methods in the field

of aging.

b4. Acquir the ability for writing

of papers.

b5. Select the prper scientific

information from heh/his

readings.

C.Professional

and Practical

Skills

C4. Develop the capability of



c1. Implement knowledge about the

major metabolic diseases in the


D. General

Skills






d1. Adopt the ability for presentation

skills.

d2. Acquire the capability of evaluation

of different data.

E. Ethics and

Attitudes




students and junior staff

e1. Promote good relations with seniors,

colleagues and students throughout

the work period.

e2. Act in the lab as a good example for

all the juniors and assessments.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes an overview on

the metabolic changes in common

diseases in the society as diabetes

mellitus, hypertension, CVS diseases

(atherosclerosis) , schestosomiasis,

chronic neurodegenerative diseases (

Alzheimer, Parkinsonism) etc. with

special emphasis on metabolic

changes of aging.

✓ ✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term 30%

End of term 70%


Written Exam 70%


Others 30%

✓ ✓

✓ ✓

✓


Lecture Notes

-

Course Text Books

• Biochemistry. Case oriented approach.

• Biochemistry. Stryer

• Lehninger Biochemistry

• Molecular cell Biology. Lodish


• Recent publications

• Any specialized text books


Relevant journals

Course Instructor

Name: Prof. Dr: Samia Mohamed Eliwa Signature:

Program Coordinator






Faculty: Medicine


Course Information

Course Code: 05160912 Course Name: Project in Biochemistry



Course Aims: The students Should be trained to do directed laboratory research performed under

the supervision of a faculty member.



matrix)

Course ILOs

A. Knowledge

and

Understanding

B. Intellectual

skills












biology lab.

b1. Use different information in problrm

solving.

b2. Appraise recent papers in

biochemistry and molecular biology.

b3. Modify laboratory methods to help in

getting better results.

b4. Use the recent information in


lab.

2 -

B5. Prepare good research

projects.

b5. Acquire the ability to prepare good

research project.

C.Professional

and Practical

Skills



biochemistry.



diagnosis of congenital diseases.



not present.

C4. Implement knowledge about

signaling in researches e.g. To



C5. Write and publish scientific

papers.

C6. Explain scientific information

to students and peers.

c1. Perfect basic techniques in clinical

chemistry.

c2. Apply modern biochemical and

molecular biology techniques.

c3. Use different methods if ideal lab


c4. Use recent knowledge in promoting

research methods.

c5. Acquire the capacity of Writing and

publishing scientific papers.

c6. Share in scientific discussions with

students and peers.

D. General

Skills

D1. Working in multi-

professional team.


d1. Adopt the ability to work in multi-

professional team.

d2. Acquire good leadership skills.

d3. Acquire good writing and


E. Ethics and

Attitudes


sterilization and infection control

in laboratory.

e1. Implement principles of sterilization

and infection control in laboratory.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes directed

laboratory research performed under

the supervision of a faculty member.

Each student is required to carry out

one detailed study of the scientific

literature related to the subject of the

research applied.

√ √


Student Assessment



Case OSCE/OSPE


Others


Mid-term 20 %

End of term 80 %


Written Exam


Others 30 %

√

√

√


Lecture Notes

Course Text Books

1. Varley. Biochemical methods


Fundamentals of clinical Chemistry. Titz


Any relevant journals

Course Instructor

Name: Dr. Iman Soliman Kamha Signature:

Program Coordinator


Program Director




Faculty: Medicine


Course Information

Course Code: 05160913 Course Name: lab. Management

Program in which the Course is Given :Doctorate Degree of Medical Biochemistry.


Course Aims:

1. Develop updated and advanced knowledge in measurement of the precision and accuracy

of the lab, check the methods and reagents, calibration of the instruments and performance,

criteria of the control material Medical Biochemistry and Molecular Biology .

2. Prepare the students to be efficient researches.

3. Apply recent laboratory investigations and recent researches in Medical Biochemistry

and molecular genetics.



matrix) Course ILOs

A. Knowledge

and

Understanding

A1. Revise and upgrade the

knowledge about how to manage

the laboratory technically

administratively and financially.

a1. Revise the general principles of how

to measure the lab precision and

accuracy .

a2. Discuss the principles of calibration

of the instruments , performance and

criteria of the control material.

B. Intellectual

skills







biology lab.



sensitivity and specificity

1

C.Professional

and Practical

Skills



biochemistry.



not present.

c1. Apply perfectly basic techniques

used in precautions for sample

collection, sample storage,

transportation, and waste disposal,

storages of quality assurance (pre-

analytic, analytic, post-analytic).

c2. Establish the mean and standard

deviation and plotting of control data

on a chart.

c3. Identify the source of analytic error

and assessment errors.

c4. Improve lab techniques used for


D. General

Skills




d1 Develop efficient writing and


E. Ethics and

Attitudes



techniques


sterilization and infection

control in laboratory

e1 Keep patient's privacy and

confidentiality.

e2 Promote good relations with seniors,

colleagues and student.

e3 Implement strictly the roles of

sterilization in all lab procedures

requiring it.



Lectures self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course ensures

laboratory staff and patients that

laboratory results are reliable and

relevant. Measurement of the

precision and accuracy of the lab,

check the methods and reagents,

calibration of the instruments and

performance, criteria of the control

material, establishment of mean and

standard deviation and plotting of

control data on a chart, identification

of the source of analytic error,

assessment errors, precautions for

sample collection, sample storage,

transportation, and waste disposal,

storages of quality assurance (pre-

analytic, analytic, post-analytic). The

practical sessions are applications on

the tutorials, with identification of

the source of analytic error,

assessment errors. The practical

work is done through group work or

single and concluded by discussion

and grading of the best performing

group in each session.

✓ ✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term -----

End of term 100%


Written Exam 80%

Practical/Clinical Exam ----

Others 20 %


Lecture Notes

-

Course Text Books

1. Clinical Chemistry

2. Fundamentals of clinical

Chemistry. Titz

3. Varley. Biochemical methods


- Any related recent text book


- Relevant journals & periodicals

Course Instructor

Name: Prof Dr.Amel Fouad Ketat Signature:

Program Coordinator




✓ ✓

✓



Faculty: Medicine


Course Information

Course Code: 05160914 Course Name: Seminar and Journal ClubII

Program in which the Course is Given : Doctorate Degree of Medical Biochemistry.


Course aims to let the student be acquainted with the special topics current to the field of biochemistry

and to practice the presentation skills as a faculty member.



matrix) Course ILOs

A. Knowledge

and

Understanding

B. Intellectual

skills

B5. Share in research projects.

B6. Select good papers and

research methods.

b1. Participate in research projects.

b2. Choose good relevant papers and

research methods which are

appropriate for research projects

C.Professional

and Practical

Skills

- 1

D. General &

Transferrable

Skills

D1. Acquire updated knowledge from

various sources and present it to peers

in systematized manner.

D3. Recognize and respect the views

and opinions of other team members.

D4. Use information technology to

access, evaluate, and interpret

scientific data.

d1. Adopt the ability to search for recent

information and present it to peers

clearly.

d2. Respect and discuss other opinions.

d3. Use information technology to access,

evaluate, and interpret scientific data.

E. Ethics &

Attitude

E4. Demonstrate commitment to

lifelong learning and professional

service including active participation

in professional organizations.

e1. Demonstrate commitment to lifelong

learning and professional service

including active participation

inprofessional organizations



Lectures

self

learning

Practical/

Clinical

Small

group

discussion

Others

Assignment

This course includes

special topics current to the field

of biochemistry. Topics and

format for the course may vary.

Study presentation is done by

each student under supervision

of a faculty member

✓ ✓


Student Assessment



Case OSCE/OSPE


Others


Mid-term(Written ) %

Assignment 80 %

Self learning, commitment & attitude 20%

End of term %


Written Exam %

Practical/Clinical Exam

Others 100%


Lecture Notes

-

Course Text Books

-


1. Recent publications.

2. Any specialized text books


Relevant journals.

Course Instructor:

Name: Dr: Nadia Ahmed Barghash Signature:

Program Coordinator

Name: Dr: Sabah Abdel-Hady Mahmoud Signature:



✓ ✓

✓

داتعلاا ميلعتلا ةدوج åاضل ةيموقلا ةئي ìلا · principles of the metabolism of foreign compounds in mammals. The xenobiotics covered include drugs,

Documents