Transcript
WILMS TUMOR
Introduction
HISTOLOGY
NEPHROGENIC REST
Nephrogenic rest is defined as the persisitance of metanephric tissue in the kidney after 36th of gestation
This lession precursor of wilms tumor
CYTOGENETIC
Wilms tumor suppressor gene chromosome 11p15
CLINICAL PRESENTATION
Diagnosis
Chest radiography detect pulmonary metastatis
Abdominal radiography linear calcification
Ultrasound consistency of the mass,intravascular involment
Ct scan of abdomen renal mass, anatomic extent of tumor,the precense of a normal-contralateral kidney and possibility of bialteral tumor involment
staging
Treatment
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