Wilms tumor.ppt

WILMS TUMOR

Introduction

HISTOLOGY

NEPHROGENIC REST

Nephrogenic rest is defined as the persisitance of metanephric tissue in the kidney after 36th of gestation

This lession precursor of wilms tumor

CYTOGENETIC

Wilms tumor suppressor gene chromosome 11p15

CLINICAL PRESENTATION

Diagnosis

Chest radiography detect pulmonary metastatis

Abdominal radiography linear calcification

Ultrasound consistency of the mass,intravascular involment

Ct scan of abdomen renal mass, anatomic extent of tumor,the precense of a normal-contralateral kidney and possibility of bialteral tumor involment

staging

Treatment