Transcript

Mitral Stenosis Class I MV surgery is indicated in adolescent or young adult patients

with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

Class IIa 1 MV surgery is reasonable in adolescent or young adult patients with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

2 MV surgery is reasonable in the asymptomatic adolescent or young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

Class IIb The effectiveness of MV surgery is not well established in the asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation

(Level of Evidence C

J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

CIRUGIA EN ESTENOSIS MITRAL

COMISUROTOMIAREEMPLAZO VALVULAR

ANILLO MITRAL CUERDAS TENDINEAS MUSCULOS PAPILARES

CONCEPTOS ANATOMICOS

Figure 1 Carpentierrsquos functional classification Type I normal leaflet motion Type II increased leaflet motion (leaflet prolapse) Type IIIa restricted leaflet motion during diastole and systole Type IIIb restricted leaflet motion predominantly during systole

La enfermedad mitral degenrativa A La enfermedad de Barlow B La degeneracioacuten fibroelaacutestica

ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

3 controversias aun sin resolver

Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

Clinical Investigation and Reports

Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

Circulation August 1 2006

ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

Circulation August 1 2006

Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

Time (y) Survival free of any indication for surgery ()

2 922

4 784

6 655

8 556

Rosenhek R et al Circulation 2006 1132238-2244

SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

Catherine M Otto MD and Christopher T Salerno MD

RIESGO MANEJO MORTALIDAD

MEDICO 26 vs OPERATORIA 1

The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

Enriquez-Sarano M et al N Engl J Med 2005352875-883

FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

Enriquez-Sarano M et al N Engl J Med 2005352875-883

Enriquez-Sarano M et al N Engl J Med 2005352875-883

RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

Enriquez-Sarano M et al N Engl J Med 2005352875-883

SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

ORIFICIO REGURGITANTE (ERO)

However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

Controversies in Cardiovascular Medicine

Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

Circulation 2010121804-812

Fraccioacuten de Eyeccioacuten lt 60

Diaacutemetro VI de fin de Diaacutestole gt 65mm

Diaacutemetro VI de fin de Sistole gt 40mm

Hipertensioacuten pulmonar gt 50mmHg

Orificio regurgitante efectivo ERO gt 40mm

Fibrilacioacuten auricular de Novo

CIRUGIA VALVULAR MITRAL

EN PACIENTES ASINTOMATICOS

CONCLUSION

90 EacuteXITO EN PLASTIA VALVULAR MITRAL

Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

En pacientes asintomaacuteticos

Anatoacutemicos Eco cardiograacuteficos

Adams D H et al Eur Heart J 2010eurheartjehq222

ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

Circulation August 1 2006

MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

VS

Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

VS

Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

VS

Eur J Cardiothorac Surg 2010371039-1046

Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

VS

Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

bull Lars G Svensson MD PhDa

(70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

Sobrevida 83 62 43 86 63 45

Libre de Re operacion

94 94 95 92

J Thorac Cardiovasc Surg 2008135885-893

VS

Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

bull Lars G Svensson MD PhDa

Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

J Thorac Cardiovasc Surg 2008135885-893

VS

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

REPARO MITRALTECNICAS QUIRURGICAS

HOJUELA POSTERIORRESECCION CUADRANGULAR

TRASPOSICION DE CUERDAS TENDINEAS

REIMPLATE MUSCULO PAPILAR

RESECCION TRIANGULAR

El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

CONCLUSION

El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

CONCLUSION

CONTROVERSIAS EN CIRUGIacuteA DE

LA VALVULA MITRAL

Dra Moacutenica RenterigraveaCali- Colombia

Reconstruccion tridimensional del anillo mitral

ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

Remodelacioacuten ventricular izquierda post IAM

COAPSYS DEVICE

CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

CLIP MITRAL

Imagen Ecocardiografica antes y despues de

anuloplastia del seno coronario

(C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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    CIRUGIA EN ESTENOSIS MITRAL

    COMISUROTOMIAREEMPLAZO VALVULAR

    ANILLO MITRAL CUERDAS TENDINEAS MUSCULOS PAPILARES

    CONCEPTOS ANATOMICOS

    Figure 1 Carpentierrsquos functional classification Type I normal leaflet motion Type II increased leaflet motion (leaflet prolapse) Type IIIa restricted leaflet motion during diastole and systole Type IIIb restricted leaflet motion predominantly during systole

    La enfermedad mitral degenrativa A La enfermedad de Barlow B La degeneracioacuten fibroelaacutestica

    ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

    3 controversias aun sin resolver

    Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

    Clinical Investigation and Reports

    Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

    Circulation August 1 2006

    ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

    Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

    2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

    Circulation August 1 2006

    Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

    2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

    ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

    No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

    SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

    Time (y) Survival free of any indication for surgery ()

    2 922

    4 784

    6 655

    8 556

    Rosenhek R et al Circulation 2006 1132238-2244

    SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

    Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

    Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

    Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

    EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

    Catherine M Otto MD and Christopher T Salerno MD

    RIESGO MANEJO MORTALIDAD

    MEDICO 26 vs OPERATORIA 1

    The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

    Enriquez-Sarano M et al N Engl J Med 2005352875-883

    FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

    Enriquez-Sarano M et al N Engl J Med 2005352875-883

    Enriquez-Sarano M et al N Engl J Med 2005352875-883

    RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

    Enriquez-Sarano M et al N Engl J Med 2005352875-883

    SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

    ORIFICIO REGURGITANTE (ERO)

    However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

    Controversies in Cardiovascular Medicine

    Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

    Circulation 2010121804-812

    Fraccioacuten de Eyeccioacuten lt 60

    Diaacutemetro VI de fin de Diaacutestole gt 65mm

    Diaacutemetro VI de fin de Sistole gt 40mm

    Hipertensioacuten pulmonar gt 50mmHg

    Orificio regurgitante efectivo ERO gt 40mm

    Fibrilacioacuten auricular de Novo

    CIRUGIA VALVULAR MITRAL

    EN PACIENTES ASINTOMATICOS

    CONCLUSION

    90 EacuteXITO EN PLASTIA VALVULAR MITRAL

    Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

    En pacientes asintomaacuteticos

    Anatoacutemicos Eco cardiograacuteficos

    Adams D H et al Eur Heart J 2010eurheartjehq222

    ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

    Circulation August 1 2006

    MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

    VS

    Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

    bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

    3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

    4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

    ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

    VS

    Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

    Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

    Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

    Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

    VS

    Eur J Cardiothorac Surg 2010371039-1046

    Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

    A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

    Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

    VS

    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

    bull Lars G Svensson MD PhDa

    (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

    Sobrevida 83 62 43 86 63 45

    Libre de Re operacion

    94 94 95 92

    J Thorac Cardiovasc Surg 2008135885-893

    VS

    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

    bull Lars G Svensson MD PhDa

    Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

    repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

    J Thorac Cardiovasc Surg 2008135885-893

    VS

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

    REPARO MITRALTECNICAS QUIRURGICAS

    HOJUELA POSTERIORRESECCION CUADRANGULAR

    TRASPOSICION DE CUERDAS TENDINEAS

    REIMPLATE MUSCULO PAPILAR

    RESECCION TRIANGULAR

    El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

    No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

    CONCLUSION

    El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

    Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

    CONCLUSION

    CONTROVERSIAS EN CIRUGIacuteA DE

    LA VALVULA MITRAL

    Dra Moacutenica RenterigraveaCali- Colombia

    Reconstruccion tridimensional del anillo mitral

    ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

    Remodelacioacuten ventricular izquierda post IAM

    COAPSYS DEVICE

    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

    CLIP MITRAL

    Imagen Ecocardiografica antes y despues de

    anuloplastia del seno coronario

    (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

    with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

    with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

    young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

    asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

    J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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      ANILLO MITRAL CUERDAS TENDINEAS MUSCULOS PAPILARES

      CONCEPTOS ANATOMICOS

      Figure 1 Carpentierrsquos functional classification Type I normal leaflet motion Type II increased leaflet motion (leaflet prolapse) Type IIIa restricted leaflet motion during diastole and systole Type IIIb restricted leaflet motion predominantly during systole

      La enfermedad mitral degenrativa A La enfermedad de Barlow B La degeneracioacuten fibroelaacutestica

      ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

      3 controversias aun sin resolver

      Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

      Clinical Investigation and Reports

      Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

      Circulation August 1 2006

      ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

      Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

      2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

      Circulation August 1 2006

      Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

      2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

      ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

      No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

      SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

      Time (y) Survival free of any indication for surgery ()

      2 922

      4 784

      6 655

      8 556

      Rosenhek R et al Circulation 2006 1132238-2244

      SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

      Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

      Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

      Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

      EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

      Catherine M Otto MD and Christopher T Salerno MD

      RIESGO MANEJO MORTALIDAD

      MEDICO 26 vs OPERATORIA 1

      The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

      Enriquez-Sarano M et al N Engl J Med 2005352875-883

      FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

      Enriquez-Sarano M et al N Engl J Med 2005352875-883

      Enriquez-Sarano M et al N Engl J Med 2005352875-883

      RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

      Enriquez-Sarano M et al N Engl J Med 2005352875-883

      SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

      ORIFICIO REGURGITANTE (ERO)

      However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

      Controversies in Cardiovascular Medicine

      Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

      Circulation 2010121804-812

      Fraccioacuten de Eyeccioacuten lt 60

      Diaacutemetro VI de fin de Diaacutestole gt 65mm

      Diaacutemetro VI de fin de Sistole gt 40mm

      Hipertensioacuten pulmonar gt 50mmHg

      Orificio regurgitante efectivo ERO gt 40mm

      Fibrilacioacuten auricular de Novo

      CIRUGIA VALVULAR MITRAL

      EN PACIENTES ASINTOMATICOS

      CONCLUSION

      90 EacuteXITO EN PLASTIA VALVULAR MITRAL

      Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

      En pacientes asintomaacuteticos

      Anatoacutemicos Eco cardiograacuteficos

      Adams D H et al Eur Heart J 2010eurheartjehq222

      ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

      Circulation August 1 2006

      MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

      VS

      Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

      bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

      3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

      4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

      ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

      VS

      Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

      Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

      Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

      Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

      VS

      Eur J Cardiothorac Surg 2010371039-1046

      Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

      A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

      Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

      VS

      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

      bull Lars G Svensson MD PhDa

      (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

      Sobrevida 83 62 43 86 63 45

      Libre de Re operacion

      94 94 95 92

      J Thorac Cardiovasc Surg 2008135885-893

      VS

      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

      bull Lars G Svensson MD PhDa

      Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

      repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

      J Thorac Cardiovasc Surg 2008135885-893

      VS

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

      REPARO MITRALTECNICAS QUIRURGICAS

      HOJUELA POSTERIORRESECCION CUADRANGULAR

      TRASPOSICION DE CUERDAS TENDINEAS

      REIMPLATE MUSCULO PAPILAR

      RESECCION TRIANGULAR

      El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

      No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

      CONCLUSION

      El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

      Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

      CONCLUSION

      CONTROVERSIAS EN CIRUGIacuteA DE

      LA VALVULA MITRAL

      Dra Moacutenica RenterigraveaCali- Colombia

      Reconstruccion tridimensional del anillo mitral

      ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

      Remodelacioacuten ventricular izquierda post IAM

      COAPSYS DEVICE

      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

      CLIP MITRAL

      Imagen Ecocardiografica antes y despues de

      anuloplastia del seno coronario

      (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

      with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

      with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

      young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

      asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

      J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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        Figure 1 Carpentierrsquos functional classification Type I normal leaflet motion Type II increased leaflet motion (leaflet prolapse) Type IIIa restricted leaflet motion during diastole and systole Type IIIb restricted leaflet motion predominantly during systole

        La enfermedad mitral degenrativa A La enfermedad de Barlow B La degeneracioacuten fibroelaacutestica

        ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

        3 controversias aun sin resolver

        Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

        Clinical Investigation and Reports

        Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

        Circulation August 1 2006

        ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

        Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

        2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

        Circulation August 1 2006

        Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

        2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

        ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

        No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

        SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

        Time (y) Survival free of any indication for surgery ()

        2 922

        4 784

        6 655

        8 556

        Rosenhek R et al Circulation 2006 1132238-2244

        SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

        Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

        Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

        Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

        EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

        Catherine M Otto MD and Christopher T Salerno MD

        RIESGO MANEJO MORTALIDAD

        MEDICO 26 vs OPERATORIA 1

        The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

        Enriquez-Sarano M et al N Engl J Med 2005352875-883

        FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

        Enriquez-Sarano M et al N Engl J Med 2005352875-883

        Enriquez-Sarano M et al N Engl J Med 2005352875-883

        RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

        Enriquez-Sarano M et al N Engl J Med 2005352875-883

        SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

        ORIFICIO REGURGITANTE (ERO)

        However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

        Controversies in Cardiovascular Medicine

        Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

        Circulation 2010121804-812

        Fraccioacuten de Eyeccioacuten lt 60

        Diaacutemetro VI de fin de Diaacutestole gt 65mm

        Diaacutemetro VI de fin de Sistole gt 40mm

        Hipertensioacuten pulmonar gt 50mmHg

        Orificio regurgitante efectivo ERO gt 40mm

        Fibrilacioacuten auricular de Novo

        CIRUGIA VALVULAR MITRAL

        EN PACIENTES ASINTOMATICOS

        CONCLUSION

        90 EacuteXITO EN PLASTIA VALVULAR MITRAL

        Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

        En pacientes asintomaacuteticos

        Anatoacutemicos Eco cardiograacuteficos

        Adams D H et al Eur Heart J 2010eurheartjehq222

        ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

        Circulation August 1 2006

        MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

        VS

        Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

        bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

        3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

        4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

        ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

        VS

        Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

        Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

        Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

        Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

        VS

        Eur J Cardiothorac Surg 2010371039-1046

        Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

        A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

        Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

        VS

        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

        bull Lars G Svensson MD PhDa

        (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

        Sobrevida 83 62 43 86 63 45

        Libre de Re operacion

        94 94 95 92

        J Thorac Cardiovasc Surg 2008135885-893

        VS

        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

        bull Lars G Svensson MD PhDa

        Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

        repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

        J Thorac Cardiovasc Surg 2008135885-893

        VS

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

        REPARO MITRALTECNICAS QUIRURGICAS

        HOJUELA POSTERIORRESECCION CUADRANGULAR

        TRASPOSICION DE CUERDAS TENDINEAS

        REIMPLATE MUSCULO PAPILAR

        RESECCION TRIANGULAR

        El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

        No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

        CONCLUSION

        El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

        Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

        CONCLUSION

        CONTROVERSIAS EN CIRUGIacuteA DE

        LA VALVULA MITRAL

        Dra Moacutenica RenterigraveaCali- Colombia

        Reconstruccion tridimensional del anillo mitral

        ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

        Remodelacioacuten ventricular izquierda post IAM

        COAPSYS DEVICE

        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

        CLIP MITRAL

        Imagen Ecocardiografica antes y despues de

        anuloplastia del seno coronario

        (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

        with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

        with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

        young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

        asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

        J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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        • Slide 43

          La enfermedad mitral degenrativa A La enfermedad de Barlow B La degeneracioacuten fibroelaacutestica

          ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

          3 controversias aun sin resolver

          Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

          Clinical Investigation and Reports

          Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

          Circulation August 1 2006

          ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

          Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

          2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

          Circulation August 1 2006

          Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

          2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

          ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

          No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

          SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

          Time (y) Survival free of any indication for surgery ()

          2 922

          4 784

          6 655

          8 556

          Rosenhek R et al Circulation 2006 1132238-2244

          SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

          Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

          Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

          Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

          EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

          Catherine M Otto MD and Christopher T Salerno MD

          RIESGO MANEJO MORTALIDAD

          MEDICO 26 vs OPERATORIA 1

          The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

          Enriquez-Sarano M et al N Engl J Med 2005352875-883

          FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

          Enriquez-Sarano M et al N Engl J Med 2005352875-883

          Enriquez-Sarano M et al N Engl J Med 2005352875-883

          RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

          Enriquez-Sarano M et al N Engl J Med 2005352875-883

          SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

          ORIFICIO REGURGITANTE (ERO)

          However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

          Controversies in Cardiovascular Medicine

          Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

          Circulation 2010121804-812

          Fraccioacuten de Eyeccioacuten lt 60

          Diaacutemetro VI de fin de Diaacutestole gt 65mm

          Diaacutemetro VI de fin de Sistole gt 40mm

          Hipertensioacuten pulmonar gt 50mmHg

          Orificio regurgitante efectivo ERO gt 40mm

          Fibrilacioacuten auricular de Novo

          CIRUGIA VALVULAR MITRAL

          EN PACIENTES ASINTOMATICOS

          CONCLUSION

          90 EacuteXITO EN PLASTIA VALVULAR MITRAL

          Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

          En pacientes asintomaacuteticos

          Anatoacutemicos Eco cardiograacuteficos

          Adams D H et al Eur Heart J 2010eurheartjehq222

          ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

          Circulation August 1 2006

          MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

          VS

          Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

          bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

          3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

          4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

          ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

          VS

          Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

          Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

          Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

          Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

          VS

          Eur J Cardiothorac Surg 2010371039-1046

          Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

          A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

          Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

          VS

          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

          bull Lars G Svensson MD PhDa

          (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

          Sobrevida 83 62 43 86 63 45

          Libre de Re operacion

          94 94 95 92

          J Thorac Cardiovasc Surg 2008135885-893

          VS

          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

          bull Lars G Svensson MD PhDa

          Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

          repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

          J Thorac Cardiovasc Surg 2008135885-893

          VS

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

          REPARO MITRALTECNICAS QUIRURGICAS

          HOJUELA POSTERIORRESECCION CUADRANGULAR

          TRASPOSICION DE CUERDAS TENDINEAS

          REIMPLATE MUSCULO PAPILAR

          RESECCION TRIANGULAR

          El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

          No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

          CONCLUSION

          El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

          Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

          CONCLUSION

          CONTROVERSIAS EN CIRUGIacuteA DE

          LA VALVULA MITRAL

          Dra Moacutenica RenterigraveaCali- Colombia

          Reconstruccion tridimensional del anillo mitral

          ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

          Remodelacioacuten ventricular izquierda post IAM

          COAPSYS DEVICE

          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

          CLIP MITRAL

          Imagen Ecocardiografica antes y despues de

          anuloplastia del seno coronario

          (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

          with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

          with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

          young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

          asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

          J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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            ASINTOMATICOS QUE TECNICA USAR COMO MANEJAR CUANDO OPERAR LA ISQUEMIA MITRAL

            3 controversias aun sin resolver

            Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

            Clinical Investigation and Reports

            Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

            Circulation August 1 2006

            ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

            Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

            2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

            Circulation August 1 2006

            Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

            2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

            ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

            No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

            SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

            Time (y) Survival free of any indication for surgery ()

            2 922

            4 784

            6 655

            8 556

            Rosenhek R et al Circulation 2006 1132238-2244

            SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

            Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

            Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

            Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

            EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

            Catherine M Otto MD and Christopher T Salerno MD

            RIESGO MANEJO MORTALIDAD

            MEDICO 26 vs OPERATORIA 1

            The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

            Enriquez-Sarano M et al N Engl J Med 2005352875-883

            FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

            Enriquez-Sarano M et al N Engl J Med 2005352875-883

            Enriquez-Sarano M et al N Engl J Med 2005352875-883

            RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

            Enriquez-Sarano M et al N Engl J Med 2005352875-883

            SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

            ORIFICIO REGURGITANTE (ERO)

            However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

            Controversies in Cardiovascular Medicine

            Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

            Circulation 2010121804-812

            Fraccioacuten de Eyeccioacuten lt 60

            Diaacutemetro VI de fin de Diaacutestole gt 65mm

            Diaacutemetro VI de fin de Sistole gt 40mm

            Hipertensioacuten pulmonar gt 50mmHg

            Orificio regurgitante efectivo ERO gt 40mm

            Fibrilacioacuten auricular de Novo

            CIRUGIA VALVULAR MITRAL

            EN PACIENTES ASINTOMATICOS

            CONCLUSION

            90 EacuteXITO EN PLASTIA VALVULAR MITRAL

            Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

            En pacientes asintomaacuteticos

            Anatoacutemicos Eco cardiograacuteficos

            Adams D H et al Eur Heart J 2010eurheartjehq222

            ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

            Circulation August 1 2006

            MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

            VS

            Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

            bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

            3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

            4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

            ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

            VS

            Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

            Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

            Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

            Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

            VS

            Eur J Cardiothorac Surg 2010371039-1046

            Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

            A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

            Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

            VS

            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

            bull Lars G Svensson MD PhDa

            (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

            Sobrevida 83 62 43 86 63 45

            Libre de Re operacion

            94 94 95 92

            J Thorac Cardiovasc Surg 2008135885-893

            VS

            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

            bull Lars G Svensson MD PhDa

            Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

            repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

            J Thorac Cardiovasc Surg 2008135885-893

            VS

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

            REPARO MITRALTECNICAS QUIRURGICAS

            HOJUELA POSTERIORRESECCION CUADRANGULAR

            TRASPOSICION DE CUERDAS TENDINEAS

            REIMPLATE MUSCULO PAPILAR

            RESECCION TRIANGULAR

            El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

            No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

            CONCLUSION

            El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

            Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

            CONCLUSION

            CONTROVERSIAS EN CIRUGIacuteA DE

            LA VALVULA MITRAL

            Dra Moacutenica RenterigraveaCali- Colombia

            Reconstruccion tridimensional del anillo mitral

            ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

            Remodelacioacuten ventricular izquierda post IAM

            COAPSYS DEVICE

            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

            CLIP MITRAL

            Imagen Ecocardiografica antes y despues de

            anuloplastia del seno coronario

            (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

            with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

            with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

            young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

            asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

            J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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            • Slide 40
            • Slide 41
            • Slide 42
            • Slide 43

              Copyright copy2002 American Heart AssociationAvierinos J-F et al Circulation 20021061355-1361

              Clinical Investigation and Reports

              Natural History of Asymptomatic Mitral Valve Prolapse in the Community Jean-Franccedilois Avierinos MD Bernard J Gersh MB ChB DPhil L Joseph Melton III MD Kent R Bailey PhD Clarence Shub MD Rick A Nishimura MD A Jamil Tajik MD Maurice Enriquez-Sarano MD From the Division of Cardiovascular Diseases (J-FA BJG CS RAN AJT ME-S) Section of Clinical Epidemiology (LJM) and Section of Biostatistics (KRB) Mayo Clinic Rochester Minn

              Circulation August 1 2006

              ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

              Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

              2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

              Circulation August 1 2006

              Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

              2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

              ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

              No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

              SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

              Time (y) Survival free of any indication for surgery ()

              2 922

              4 784

              6 655

              8 556

              Rosenhek R et al Circulation 2006 1132238-2244

              SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

              Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

              Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

              Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

              EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

              Catherine M Otto MD and Christopher T Salerno MD

              RIESGO MANEJO MORTALIDAD

              MEDICO 26 vs OPERATORIA 1

              The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

              Enriquez-Sarano M et al N Engl J Med 2005352875-883

              FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

              Enriquez-Sarano M et al N Engl J Med 2005352875-883

              Enriquez-Sarano M et al N Engl J Med 2005352875-883

              RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

              Enriquez-Sarano M et al N Engl J Med 2005352875-883

              SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

              ORIFICIO REGURGITANTE (ERO)

              However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

              Controversies in Cardiovascular Medicine

              Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

              Circulation 2010121804-812

              Fraccioacuten de Eyeccioacuten lt 60

              Diaacutemetro VI de fin de Diaacutestole gt 65mm

              Diaacutemetro VI de fin de Sistole gt 40mm

              Hipertensioacuten pulmonar gt 50mmHg

              Orificio regurgitante efectivo ERO gt 40mm

              Fibrilacioacuten auricular de Novo

              CIRUGIA VALVULAR MITRAL

              EN PACIENTES ASINTOMATICOS

              CONCLUSION

              90 EacuteXITO EN PLASTIA VALVULAR MITRAL

              Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

              En pacientes asintomaacuteticos

              Anatoacutemicos Eco cardiograacuteficos

              Adams D H et al Eur Heart J 2010eurheartjehq222

              ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

              Circulation August 1 2006

              MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

              VS

              Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

              bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

              3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

              4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

              ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

              VS

              Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

              Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

              Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

              Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

              VS

              Eur J Cardiothorac Surg 2010371039-1046

              Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

              A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

              Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

              VS

              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

              bull Lars G Svensson MD PhDa

              (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

              Sobrevida 83 62 43 86 63 45

              Libre de Re operacion

              94 94 95 92

              J Thorac Cardiovasc Surg 2008135885-893

              VS

              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

              bull Lars G Svensson MD PhDa

              Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

              repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

              J Thorac Cardiovasc Surg 2008135885-893

              VS

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

              REPARO MITRALTECNICAS QUIRURGICAS

              HOJUELA POSTERIORRESECCION CUADRANGULAR

              TRASPOSICION DE CUERDAS TENDINEAS

              REIMPLATE MUSCULO PAPILAR

              RESECCION TRIANGULAR

              El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

              No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

              CONCLUSION

              El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

              Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

              CONCLUSION

              CONTROVERSIAS EN CIRUGIacuteA DE

              LA VALVULA MITRAL

              Dra Moacutenica RenterigraveaCali- Colombia

              Reconstruccion tridimensional del anillo mitral

              ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

              Remodelacioacuten ventricular izquierda post IAM

              COAPSYS DEVICE

              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

              CLIP MITRAL

              Imagen Ecocardiografica antes y despues de

              anuloplastia del seno coronario

              (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

              with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

              with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

              young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

              asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

              J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

              • Slide 1
              • Slide 2
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                Circulation August 1 2006

                ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                Class III1 MV surgery is not indicated for asymptomatic patients with MR and preserved LV function (ejection fraction greater than 060 and end-systolic dimensionless than 40 mm) in whom significant doubt about the feasibility of repair exists (Level of Evidence C)

                2 Isolated MV surgery is not indicated for patients withmild or moderate MR (Level of Evidence C)

                Circulation August 1 2006

                Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

                2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

                ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

                SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

                Time (y) Survival free of any indication for surgery ()

                2 922

                4 784

                6 655

                8 556

                Rosenhek R et al Circulation 2006 1132238-2244

                SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

                Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

                Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

                Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

                EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

                Catherine M Otto MD and Christopher T Salerno MD

                RIESGO MANEJO MORTALIDAD

                MEDICO 26 vs OPERATORIA 1

                The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

                Enriquez-Sarano M et al N Engl J Med 2005352875-883

                FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                Enriquez-Sarano M et al N Engl J Med 2005352875-883

                Enriquez-Sarano M et al N Engl J Med 2005352875-883

                RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                Enriquez-Sarano M et al N Engl J Med 2005352875-883

                SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                ORIFICIO REGURGITANTE (ERO)

                However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                Controversies in Cardiovascular Medicine

                Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                Circulation 2010121804-812

                Fraccioacuten de Eyeccioacuten lt 60

                Diaacutemetro VI de fin de Diaacutestole gt 65mm

                Diaacutemetro VI de fin de Sistole gt 40mm

                Hipertensioacuten pulmonar gt 50mmHg

                Orificio regurgitante efectivo ERO gt 40mm

                Fibrilacioacuten auricular de Novo

                CIRUGIA VALVULAR MITRAL

                EN PACIENTES ASINTOMATICOS

                CONCLUSION

                90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                En pacientes asintomaacuteticos

                Anatoacutemicos Eco cardiograacuteficos

                Adams D H et al Eur Heart J 2010eurheartjehq222

                ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                Circulation August 1 2006

                MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                VS

                Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                VS

                Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                VS

                Eur J Cardiothorac Surg 2010371039-1046

                Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                VS

                Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                bull Lars G Svensson MD PhDa

                (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                Sobrevida 83 62 43 86 63 45

                Libre de Re operacion

                94 94 95 92

                J Thorac Cardiovasc Surg 2008135885-893

                VS

                Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                bull Lars G Svensson MD PhDa

                Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                J Thorac Cardiovasc Surg 2008135885-893

                VS

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                REPARO MITRALTECNICAS QUIRURGICAS

                HOJUELA POSTERIORRESECCION CUADRANGULAR

                TRASPOSICION DE CUERDAS TENDINEAS

                REIMPLATE MUSCULO PAPILAR

                RESECCION TRIANGULAR

                El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                CONCLUSION

                El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                CONCLUSION

                CONTROVERSIAS EN CIRUGIacuteA DE

                LA VALVULA MITRAL

                Dra Moacutenica RenterigraveaCali- Colombia

                Reconstruccion tridimensional del anillo mitral

                ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                Remodelacioacuten ventricular izquierda post IAM

                COAPSYS DEVICE

                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                CLIP MITRAL

                Imagen Ecocardiografica antes y despues de

                anuloplastia del seno coronario

                (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                • Slide 42
                • Slide 43

                  Circulation August 1 2006

                  Class IIa1 MV repair is reasonable in experienced surgical centers for asymptomatic patients with chronic severe MR with preserved LV function (ejection fraction greater than 060 and end-systolic dimension less than 40 mm) in whom the likelihood of successful repair without residual MR is greater than 90(Level of Evidence B)

                  2 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and new onset of atrial fibrillation (Level of Evidence C)3 MV surgery is reasonable for asymptomatic patients with chronic severe MR preserved LV function and pulmonary hypertension (pulmonary artery systolicpressure greater than 50 mm Hg at rest or greaterthan 60 mm Hg on exercise)

                  ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                  No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

                  SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

                  Time (y) Survival free of any indication for surgery ()

                  2 922

                  4 784

                  6 655

                  8 556

                  Rosenhek R et al Circulation 2006 1132238-2244

                  SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

                  Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

                  Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

                  Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

                  EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

                  Catherine M Otto MD and Christopher T Salerno MD

                  RIESGO MANEJO MORTALIDAD

                  MEDICO 26 vs OPERATORIA 1

                  The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

                  Enriquez-Sarano M et al N Engl J Med 2005352875-883

                  FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                  Enriquez-Sarano M et al N Engl J Med 2005352875-883

                  Enriquez-Sarano M et al N Engl J Med 2005352875-883

                  RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                  Enriquez-Sarano M et al N Engl J Med 2005352875-883

                  SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                  ORIFICIO REGURGITANTE (ERO)

                  However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                  Controversies in Cardiovascular Medicine

                  Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                  Circulation 2010121804-812

                  Fraccioacuten de Eyeccioacuten lt 60

                  Diaacutemetro VI de fin de Diaacutestole gt 65mm

                  Diaacutemetro VI de fin de Sistole gt 40mm

                  Hipertensioacuten pulmonar gt 50mmHg

                  Orificio regurgitante efectivo ERO gt 40mm

                  Fibrilacioacuten auricular de Novo

                  CIRUGIA VALVULAR MITRAL

                  EN PACIENTES ASINTOMATICOS

                  CONCLUSION

                  90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                  Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                  En pacientes asintomaacuteticos

                  Anatoacutemicos Eco cardiograacuteficos

                  Adams D H et al Eur Heart J 2010eurheartjehq222

                  ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                  Circulation August 1 2006

                  MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                  VS

                  Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                  bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                  3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                  4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                  ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                  VS

                  Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                  Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                  Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                  Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                  VS

                  Eur J Cardiothorac Surg 2010371039-1046

                  Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                  A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                  Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                  VS

                  Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                  Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                  Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                  bull Lars G Svensson MD PhDa

                  (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                  Sobrevida 83 62 43 86 63 45

                  Libre de Re operacion

                  94 94 95 92

                  J Thorac Cardiovasc Surg 2008135885-893

                  VS

                  Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                  Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                  Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                  bull Lars G Svensson MD PhDa

                  Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                  repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                  J Thorac Cardiovasc Surg 2008135885-893

                  VS

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                  REPARO MITRALTECNICAS QUIRURGICAS

                  HOJUELA POSTERIORRESECCION CUADRANGULAR

                  TRASPOSICION DE CUERDAS TENDINEAS

                  REIMPLATE MUSCULO PAPILAR

                  RESECCION TRIANGULAR

                  El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                  No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                  CONCLUSION

                  El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                  Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                  CONCLUSION

                  CONTROVERSIAS EN CIRUGIacuteA DE

                  LA VALVULA MITRAL

                  Dra Moacutenica RenterigraveaCali- Colombia

                  Reconstruccion tridimensional del anillo mitral

                  ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                  Remodelacioacuten ventricular izquierda post IAM

                  COAPSYS DEVICE

                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                  CLIP MITRAL

                  Imagen Ecocardiografica antes y despues de

                  anuloplastia del seno coronario

                  (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                  with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                  with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                  young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                  asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                  J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                    No need to rush to surgery in asymptomatic patients with severe mitral Regurgitation MAY 4 2006 |

                    SOBREVIDA LIBRE DE NECESIDAD DE CIRUGIgraveA

                    Time (y) Survival free of any indication for surgery ()

                    2 922

                    4 784

                    6 655

                    8 556

                    Rosenhek R et al Circulation 2006 1132238-2244

                    SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

                    Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

                    Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

                    Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

                    EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

                    Catherine M Otto MD and Christopher T Salerno MD

                    RIESGO MANEJO MORTALIDAD

                    MEDICO 26 vs OPERATORIA 1

                    The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

                    Enriquez-Sarano M et al N Engl J Med 2005352875-883

                    FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                    Enriquez-Sarano M et al N Engl J Med 2005352875-883

                    Enriquez-Sarano M et al N Engl J Med 2005352875-883

                    RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                    Enriquez-Sarano M et al N Engl J Med 2005352875-883

                    SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                    ORIFICIO REGURGITANTE (ERO)

                    However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                    Controversies in Cardiovascular Medicine

                    Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                    Circulation 2010121804-812

                    Fraccioacuten de Eyeccioacuten lt 60

                    Diaacutemetro VI de fin de Diaacutestole gt 65mm

                    Diaacutemetro VI de fin de Sistole gt 40mm

                    Hipertensioacuten pulmonar gt 50mmHg

                    Orificio regurgitante efectivo ERO gt 40mm

                    Fibrilacioacuten auricular de Novo

                    CIRUGIA VALVULAR MITRAL

                    EN PACIENTES ASINTOMATICOS

                    CONCLUSION

                    90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                    Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                    En pacientes asintomaacuteticos

                    Anatoacutemicos Eco cardiograacuteficos

                    Adams D H et al Eur Heart J 2010eurheartjehq222

                    ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                    Circulation August 1 2006

                    MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                    VS

                    Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                    bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                    3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                    4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                    ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                    VS

                    Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                    Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                    Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                    Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                    VS

                    Eur J Cardiothorac Surg 2010371039-1046

                    Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                    A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                    Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                    VS

                    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                    bull Lars G Svensson MD PhDa

                    (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                    Sobrevida 83 62 43 86 63 45

                    Libre de Re operacion

                    94 94 95 92

                    J Thorac Cardiovasc Surg 2008135885-893

                    VS

                    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                    bull Lars G Svensson MD PhDa

                    Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                    repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                    J Thorac Cardiovasc Surg 2008135885-893

                    VS

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                    REPARO MITRALTECNICAS QUIRURGICAS

                    HOJUELA POSTERIORRESECCION CUADRANGULAR

                    TRASPOSICION DE CUERDAS TENDINEAS

                    REIMPLATE MUSCULO PAPILAR

                    RESECCION TRIANGULAR

                    El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                    No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                    CONCLUSION

                    El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                    Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                    CONCLUSION

                    CONTROVERSIAS EN CIRUGIacuteA DE

                    LA VALVULA MITRAL

                    Dra Moacutenica RenterigraveaCali- Colombia

                    Reconstruccion tridimensional del anillo mitral

                    ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                    Remodelacioacuten ventricular izquierda post IAM

                    COAPSYS DEVICE

                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                    CLIP MITRAL

                    Imagen Ecocardiografica antes y despues de

                    anuloplastia del seno coronario

                    (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                    with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                    with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                    young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                    asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                    J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                    • Slide 1
                    • Slide 2
                    • Slide 3
                    • Slide 4
                    • Slide 5
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                      SOBREVIDA A LARGO PLAZO EN ENINSUFICIENCIAMITRAL SEVERA

                      Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

                      Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

                      Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

                      EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

                      Catherine M Otto MD and Christopher T Salerno MD

                      RIESGO MANEJO MORTALIDAD

                      MEDICO 26 vs OPERATORIA 1

                      The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

                      Enriquez-Sarano M et al N Engl J Med 2005352875-883

                      FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                      Enriquez-Sarano M et al N Engl J Med 2005352875-883

                      Enriquez-Sarano M et al N Engl J Med 2005352875-883

                      RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                      Enriquez-Sarano M et al N Engl J Med 2005352875-883

                      SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                      ORIFICIO REGURGITANTE (ERO)

                      However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                      Controversies in Cardiovascular Medicine

                      Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                      Circulation 2010121804-812

                      Fraccioacuten de Eyeccioacuten lt 60

                      Diaacutemetro VI de fin de Diaacutestole gt 65mm

                      Diaacutemetro VI de fin de Sistole gt 40mm

                      Hipertensioacuten pulmonar gt 50mmHg

                      Orificio regurgitante efectivo ERO gt 40mm

                      Fibrilacioacuten auricular de Novo

                      CIRUGIA VALVULAR MITRAL

                      EN PACIENTES ASINTOMATICOS

                      CONCLUSION

                      90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                      Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                      En pacientes asintomaacuteticos

                      Anatoacutemicos Eco cardiograacuteficos

                      Adams D H et al Eur Heart J 2010eurheartjehq222

                      ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                      Circulation August 1 2006

                      MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                      VS

                      Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                      bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                      3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                      4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                      ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                      VS

                      Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                      Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                      Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                      Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                      VS

                      Eur J Cardiothorac Surg 2010371039-1046

                      Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                      A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                      Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                      VS

                      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                      bull Lars G Svensson MD PhDa

                      (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                      Sobrevida 83 62 43 86 63 45

                      Libre de Re operacion

                      94 94 95 92

                      J Thorac Cardiovasc Surg 2008135885-893

                      VS

                      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                      bull Lars G Svensson MD PhDa

                      Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                      repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                      J Thorac Cardiovasc Surg 2008135885-893

                      VS

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                      REPARO MITRALTECNICAS QUIRURGICAS

                      HOJUELA POSTERIORRESECCION CUADRANGULAR

                      TRASPOSICION DE CUERDAS TENDINEAS

                      REIMPLATE MUSCULO PAPILAR

                      RESECCION TRIANGULAR

                      El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                      No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                      CONCLUSION

                      El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                      Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                      CONCLUSION

                      CONTROVERSIAS EN CIRUGIacuteA DE

                      LA VALVULA MITRAL

                      Dra Moacutenica RenterigraveaCali- Colombia

                      Reconstruccion tridimensional del anillo mitral

                      ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                      Remodelacioacuten ventricular izquierda post IAM

                      COAPSYS DEVICE

                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                      CLIP MITRAL

                      Imagen Ecocardiografica antes y despues de

                      anuloplastia del seno coronario

                      (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                      with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                      with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                      young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                      asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                      J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                      • Slide 1
                      • Slide 2
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                      • Slide 41
                      • Slide 42
                      • Slide 43

                        Conclusions Quantitative grading of mitral regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation Patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery

                        Quantitative Determinants of the Outcome of Asymptomatic Mitral Regurgitation

                        Maurice Enriquez-Sarano MD Jean-Franccedilois Avierinos MD David Messika-Zeitoun MD Delphine Detaint MD Maryann Capps RDCS Vuyisile Nkomo MD Christopher Scott MS Hartzell V Schaff MD and A Jamil Tajik MD

                        EDITORIALTiming of Surgery in Asymptomatic Mitral Regurgitation

                        Catherine M Otto MD and Christopher T Salerno MD

                        RIESGO MANEJO MORTALIDAD

                        MEDICO 26 vs OPERATORIA 1

                        The New England Journal of medicineVolume 352875-883 March 3 2005 Number 9

                        Enriquez-Sarano M et al N Engl J Med 2005352875-883

                        FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                        Enriquez-Sarano M et al N Engl J Med 2005352875-883

                        Enriquez-Sarano M et al N Engl J Med 2005352875-883

                        RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                        Enriquez-Sarano M et al N Engl J Med 2005352875-883

                        SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                        ORIFICIO REGURGITANTE (ERO)

                        However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                        Controversies in Cardiovascular Medicine

                        Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                        Circulation 2010121804-812

                        Fraccioacuten de Eyeccioacuten lt 60

                        Diaacutemetro VI de fin de Diaacutestole gt 65mm

                        Diaacutemetro VI de fin de Sistole gt 40mm

                        Hipertensioacuten pulmonar gt 50mmHg

                        Orificio regurgitante efectivo ERO gt 40mm

                        Fibrilacioacuten auricular de Novo

                        CIRUGIA VALVULAR MITRAL

                        EN PACIENTES ASINTOMATICOS

                        CONCLUSION

                        90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                        Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                        En pacientes asintomaacuteticos

                        Anatoacutemicos Eco cardiograacuteficos

                        Adams D H et al Eur Heart J 2010eurheartjehq222

                        ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                        Circulation August 1 2006

                        MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                        VS

                        Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                        bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                        3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                        4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                        ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                        VS

                        Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                        Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                        Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                        Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                        VS

                        Eur J Cardiothorac Surg 2010371039-1046

                        Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                        A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                        Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                        VS

                        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                        bull Lars G Svensson MD PhDa

                        (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                        Sobrevida 83 62 43 86 63 45

                        Libre de Re operacion

                        94 94 95 92

                        J Thorac Cardiovasc Surg 2008135885-893

                        VS

                        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                        bull Lars G Svensson MD PhDa

                        Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                        repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                        J Thorac Cardiovasc Surg 2008135885-893

                        VS

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                        REPARO MITRALTECNICAS QUIRURGICAS

                        HOJUELA POSTERIORRESECCION CUADRANGULAR

                        TRASPOSICION DE CUERDAS TENDINEAS

                        REIMPLATE MUSCULO PAPILAR

                        RESECCION TRIANGULAR

                        El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                        No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                        CONCLUSION

                        El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                        Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                        CONCLUSION

                        CONTROVERSIAS EN CIRUGIacuteA DE

                        LA VALVULA MITRAL

                        Dra Moacutenica RenterigraveaCali- Colombia

                        Reconstruccion tridimensional del anillo mitral

                        ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                        Remodelacioacuten ventricular izquierda post IAM

                        COAPSYS DEVICE

                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                        CLIP MITRAL

                        Imagen Ecocardiografica antes y despues de

                        anuloplastia del seno coronario

                        (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                        with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                        with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                        young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                        asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                        J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                        • Slide 1
                        • Slide 2
                        • Slide 3
                        • Slide 4
                        • Slide 5
                        • Slide 6
                        • Slide 7
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                          Enriquez-Sarano M et al N Engl J Med 2005352875-883

                          FACTORES DE RIESGO DE MUERTE EN PACIENTES ASINTOMATICOS CON INSUFICIENCIA MITRAL SEVERA NO SINTOAMATICA

                          Enriquez-Sarano M et al N Engl J Med 2005352875-883

                          Enriquez-Sarano M et al N Engl J Med 2005352875-883

                          RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                          Enriquez-Sarano M et al N Engl J Med 2005352875-883

                          SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                          ORIFICIO REGURGITANTE (ERO)

                          However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                          Controversies in Cardiovascular Medicine

                          Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                          Circulation 2010121804-812

                          Fraccioacuten de Eyeccioacuten lt 60

                          Diaacutemetro VI de fin de Diaacutestole gt 65mm

                          Diaacutemetro VI de fin de Sistole gt 40mm

                          Hipertensioacuten pulmonar gt 50mmHg

                          Orificio regurgitante efectivo ERO gt 40mm

                          Fibrilacioacuten auricular de Novo

                          CIRUGIA VALVULAR MITRAL

                          EN PACIENTES ASINTOMATICOS

                          CONCLUSION

                          90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                          Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                          En pacientes asintomaacuteticos

                          Anatoacutemicos Eco cardiograacuteficos

                          Adams D H et al Eur Heart J 2010eurheartjehq222

                          ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                          Circulation August 1 2006

                          MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                          VS

                          Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                          bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                          3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                          4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                          ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                          VS

                          Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                          Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                          Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                          Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                          VS

                          Eur J Cardiothorac Surg 2010371039-1046

                          Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                          A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                          Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                          VS

                          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                          bull Lars G Svensson MD PhDa

                          (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                          Sobrevida 83 62 43 86 63 45

                          Libre de Re operacion

                          94 94 95 92

                          J Thorac Cardiovasc Surg 2008135885-893

                          VS

                          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                          bull Lars G Svensson MD PhDa

                          Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                          repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                          J Thorac Cardiovasc Surg 2008135885-893

                          VS

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                          REPARO MITRALTECNICAS QUIRURGICAS

                          HOJUELA POSTERIORRESECCION CUADRANGULAR

                          TRASPOSICION DE CUERDAS TENDINEAS

                          REIMPLATE MUSCULO PAPILAR

                          RESECCION TRIANGULAR

                          El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                          No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                          CONCLUSION

                          El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                          Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                          CONCLUSION

                          CONTROVERSIAS EN CIRUGIacuteA DE

                          LA VALVULA MITRAL

                          Dra Moacutenica RenterigraveaCali- Colombia

                          Reconstruccion tridimensional del anillo mitral

                          ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                          Remodelacioacuten ventricular izquierda post IAM

                          COAPSYS DEVICE

                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                          CLIP MITRAL

                          Imagen Ecocardiografica antes y despues de

                          anuloplastia del seno coronario

                          (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                          with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                          with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                          young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                          asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                          J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                          • Slide 1
                          • Slide 2
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                          • Slide 43

                            Enriquez-Sarano M et al N Engl J Med 2005352875-883

                            RIESGO DE MUERTE DE ACUERDO AL AREA DEL ORIFICIO REGURGITANTE (ERO)EN PACIENTES EN MANEJO MEDICO

                            Enriquez-Sarano M et al N Engl J Med 2005352875-883

                            SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                            ORIFICIO REGURGITANTE (ERO)

                            However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                            Controversies in Cardiovascular Medicine

                            Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                            Circulation 2010121804-812

                            Fraccioacuten de Eyeccioacuten lt 60

                            Diaacutemetro VI de fin de Diaacutestole gt 65mm

                            Diaacutemetro VI de fin de Sistole gt 40mm

                            Hipertensioacuten pulmonar gt 50mmHg

                            Orificio regurgitante efectivo ERO gt 40mm

                            Fibrilacioacuten auricular de Novo

                            CIRUGIA VALVULAR MITRAL

                            EN PACIENTES ASINTOMATICOS

                            CONCLUSION

                            90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                            Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                            En pacientes asintomaacuteticos

                            Anatoacutemicos Eco cardiograacuteficos

                            Adams D H et al Eur Heart J 2010eurheartjehq222

                            ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                            Circulation August 1 2006

                            MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                            VS

                            Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                            bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                            3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                            4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                            ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                            VS

                            Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                            Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                            Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                            Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                            VS

                            Eur J Cardiothorac Surg 2010371039-1046

                            Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                            A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                            Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                            VS

                            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                            bull Lars G Svensson MD PhDa

                            (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                            Sobrevida 83 62 43 86 63 45

                            Libre de Re operacion

                            94 94 95 92

                            J Thorac Cardiovasc Surg 2008135885-893

                            VS

                            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                            bull Lars G Svensson MD PhDa

                            Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                            repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                            J Thorac Cardiovasc Surg 2008135885-893

                            VS

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                            REPARO MITRALTECNICAS QUIRURGICAS

                            HOJUELA POSTERIORRESECCION CUADRANGULAR

                            TRASPOSICION DE CUERDAS TENDINEAS

                            REIMPLATE MUSCULO PAPILAR

                            RESECCION TRIANGULAR

                            El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                            No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                            CONCLUSION

                            El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                            Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                            CONCLUSION

                            CONTROVERSIAS EN CIRUGIacuteA DE

                            LA VALVULA MITRAL

                            Dra Moacutenica RenterigraveaCali- Colombia

                            Reconstruccion tridimensional del anillo mitral

                            ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                            Remodelacioacuten ventricular izquierda post IAM

                            COAPSYS DEVICE

                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                            CLIP MITRAL

                            Imagen Ecocardiografica antes y despues de

                            anuloplastia del seno coronario

                            (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                            with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                            with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                            young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                            asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                            J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                            • Slide 1
                            • Slide 2
                            • Slide 3
                            • Slide 4
                            • Slide 5
                            • Slide 6
                            • Slide 7
                            • Slide 8
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                              Enriquez-Sarano M et al N Engl J Med 2005352875-883

                              SOBREVIDA ( KAPLAN MEIER) EN PACIENTES ASINTOMATICOS DE EN PACIENTES EN MANEJO MEDICO DE ACUERDO AL AREA DEL

                              ORIFICIO REGURGITANTE (ERO)

                              However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                              Controversies in Cardiovascular Medicine

                              Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                              Circulation 2010121804-812

                              Fraccioacuten de Eyeccioacuten lt 60

                              Diaacutemetro VI de fin de Diaacutestole gt 65mm

                              Diaacutemetro VI de fin de Sistole gt 40mm

                              Hipertensioacuten pulmonar gt 50mmHg

                              Orificio regurgitante efectivo ERO gt 40mm

                              Fibrilacioacuten auricular de Novo

                              CIRUGIA VALVULAR MITRAL

                              EN PACIENTES ASINTOMATICOS

                              CONCLUSION

                              90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                              Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                              En pacientes asintomaacuteticos

                              Anatoacutemicos Eco cardiograacuteficos

                              Adams D H et al Eur Heart J 2010eurheartjehq222

                              ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                              Circulation August 1 2006

                              MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                              VS

                              Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                              bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                              3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                              4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                              ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                              VS

                              Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                              Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                              Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                              Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                              VS

                              Eur J Cardiothorac Surg 2010371039-1046

                              Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                              A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                              Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                              VS

                              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                              bull Lars G Svensson MD PhDa

                              (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                              Sobrevida 83 62 43 86 63 45

                              Libre de Re operacion

                              94 94 95 92

                              J Thorac Cardiovasc Surg 2008135885-893

                              VS

                              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                              bull Lars G Svensson MD PhDa

                              Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                              repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                              J Thorac Cardiovasc Surg 2008135885-893

                              VS

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                              REPARO MITRALTECNICAS QUIRURGICAS

                              HOJUELA POSTERIORRESECCION CUADRANGULAR

                              TRASPOSICION DE CUERDAS TENDINEAS

                              REIMPLATE MUSCULO PAPILAR

                              RESECCION TRIANGULAR

                              El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                              No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                              CONCLUSION

                              El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                              Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                              CONCLUSION

                              CONTROVERSIAS EN CIRUGIacuteA DE

                              LA VALVULA MITRAL

                              Dra Moacutenica RenterigraveaCali- Colombia

                              Reconstruccion tridimensional del anillo mitral

                              ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                              Remodelacioacuten ventricular izquierda post IAM

                              COAPSYS DEVICE

                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                              CLIP MITRAL

                              Imagen Ecocardiografica antes y despues de

                              anuloplastia del seno coronario

                              (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                              with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                              with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                              young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                              asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                              J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                              • Slide 1
                              • Slide 2
                              • Slide 3
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                              • Slide 42
                              • Slide 43

                                However we illustrate here that overwhelmingly coherent cumulative evidence obtained worldwide shows that early surgery should be the preferred management approach for organic MR This approach differs from standard guidelines and it is essential that its principles rationales and conduct be fully considered

                                Controversies in Cardiovascular Medicine

                                Is early surgery recommended for mitral regurgitationEarly Surgery Is Recommended for Mitral RegurgitationMaurice Enriquez-Sarano MD Thoralf M Sundt III MD From the Divisions of Cardiovascular Diseases and Internal Medicine (ME-S) and Cardiac Surgery (TMS) Mayo Clinic Rochester Minn

                                Circulation 2010121804-812

                                Fraccioacuten de Eyeccioacuten lt 60

                                Diaacutemetro VI de fin de Diaacutestole gt 65mm

                                Diaacutemetro VI de fin de Sistole gt 40mm

                                Hipertensioacuten pulmonar gt 50mmHg

                                Orificio regurgitante efectivo ERO gt 40mm

                                Fibrilacioacuten auricular de Novo

                                CIRUGIA VALVULAR MITRAL

                                EN PACIENTES ASINTOMATICOS

                                CONCLUSION

                                90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                                Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                                En pacientes asintomaacuteticos

                                Anatoacutemicos Eco cardiograacuteficos

                                Adams D H et al Eur Heart J 2010eurheartjehq222

                                ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                                Circulation August 1 2006

                                MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                                VS

                                Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                                bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                                3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                                4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                                ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                                VS

                                Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                VS

                                Eur J Cardiothorac Surg 2010371039-1046

                                Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                VS

                                Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                bull Lars G Svensson MD PhDa

                                (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                Sobrevida 83 62 43 86 63 45

                                Libre de Re operacion

                                94 94 95 92

                                J Thorac Cardiovasc Surg 2008135885-893

                                VS

                                Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                bull Lars G Svensson MD PhDa

                                Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                J Thorac Cardiovasc Surg 2008135885-893

                                VS

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                REPARO MITRALTECNICAS QUIRURGICAS

                                HOJUELA POSTERIORRESECCION CUADRANGULAR

                                TRASPOSICION DE CUERDAS TENDINEAS

                                REIMPLATE MUSCULO PAPILAR

                                RESECCION TRIANGULAR

                                El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                CONCLUSION

                                El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                CONCLUSION

                                CONTROVERSIAS EN CIRUGIacuteA DE

                                LA VALVULA MITRAL

                                Dra Moacutenica RenterigraveaCali- Colombia

                                Reconstruccion tridimensional del anillo mitral

                                ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                Remodelacioacuten ventricular izquierda post IAM

                                COAPSYS DEVICE

                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                CLIP MITRAL

                                Imagen Ecocardiografica antes y despues de

                                anuloplastia del seno coronario

                                (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                • Slide 1
                                • Slide 2
                                • Slide 3
                                • Slide 4
                                • Slide 5
                                • Slide 6
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                                • Slide 43

                                  Fraccioacuten de Eyeccioacuten lt 60

                                  Diaacutemetro VI de fin de Diaacutestole gt 65mm

                                  Diaacutemetro VI de fin de Sistole gt 40mm

                                  Hipertensioacuten pulmonar gt 50mmHg

                                  Orificio regurgitante efectivo ERO gt 40mm

                                  Fibrilacioacuten auricular de Novo

                                  CIRUGIA VALVULAR MITRAL

                                  EN PACIENTES ASINTOMATICOS

                                  CONCLUSION

                                  90 EacuteXITO EN PLASTIA VALVULAR MITRAL

                                  Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                                  En pacientes asintomaacuteticos

                                  Anatoacutemicos Eco cardiograacuteficos

                                  Adams D H et al Eur Heart J 2010eurheartjehq222

                                  ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                                  Circulation August 1 2006

                                  MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                                  VS

                                  Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                                  bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                                  3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                                  4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                                  ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                                  VS

                                  Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                  Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                  Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                  Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                  VS

                                  Eur J Cardiothorac Surg 2010371039-1046

                                  Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                  A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                  Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                  VS

                                  Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                  Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                  Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                  bull Lars G Svensson MD PhDa

                                  (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                  Sobrevida 83 62 43 86 63 45

                                  Libre de Re operacion

                                  94 94 95 92

                                  J Thorac Cardiovasc Surg 2008135885-893

                                  VS

                                  Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                  Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                  Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                  bull Lars G Svensson MD PhDa

                                  Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                  repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                  J Thorac Cardiovasc Surg 2008135885-893

                                  VS

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                  REPARO MITRALTECNICAS QUIRURGICAS

                                  HOJUELA POSTERIORRESECCION CUADRANGULAR

                                  TRASPOSICION DE CUERDAS TENDINEAS

                                  REIMPLATE MUSCULO PAPILAR

                                  RESECCION TRIANGULAR

                                  El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                  No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                  CONCLUSION

                                  El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                  Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                  CONCLUSION

                                  CONTROVERSIAS EN CIRUGIacuteA DE

                                  LA VALVULA MITRAL

                                  Dra Moacutenica RenterigraveaCali- Colombia

                                  Reconstruccion tridimensional del anillo mitral

                                  ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                  Remodelacioacuten ventricular izquierda post IAM

                                  COAPSYS DEVICE

                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                  CLIP MITRAL

                                  Imagen Ecocardiografica antes y despues de

                                  anuloplastia del seno coronario

                                  (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                  with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                  with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                  young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                  asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                  J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                  • Slide 1
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                                  • Slide 40
                                  • Slide 41
                                  • Slide 42
                                  • Slide 43

                                    Factores a considerar para definir el tiempo ideal de cirugiacutea en vaacutelvula mitral

                                    En pacientes asintomaacuteticos

                                    Anatoacutemicos Eco cardiograacuteficos

                                    Adams D H et al Eur Heart J 2010eurheartjehq222

                                    ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                                    Circulation August 1 2006

                                    MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                                    VS

                                    Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                                    bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                                    3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                                    4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                                    ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                                    VS

                                    Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                    Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                    Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                    Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                    VS

                                    Eur J Cardiothorac Surg 2010371039-1046

                                    Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                    A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                    Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                    VS

                                    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                    bull Lars G Svensson MD PhDa

                                    (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                    Sobrevida 83 62 43 86 63 45

                                    Libre de Re operacion

                                    94 94 95 92

                                    J Thorac Cardiovasc Surg 2008135885-893

                                    VS

                                    Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                    Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                    Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                    bull Lars G Svensson MD PhDa

                                    Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                    repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                    J Thorac Cardiovasc Surg 2008135885-893

                                    VS

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                    REPARO MITRALTECNICAS QUIRURGICAS

                                    HOJUELA POSTERIORRESECCION CUADRANGULAR

                                    TRASPOSICION DE CUERDAS TENDINEAS

                                    REIMPLATE MUSCULO PAPILAR

                                    RESECCION TRIANGULAR

                                    El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                    No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                    CONCLUSION

                                    El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                    Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                    CONCLUSION

                                    CONTROVERSIAS EN CIRUGIacuteA DE

                                    LA VALVULA MITRAL

                                    Dra Moacutenica RenterigraveaCali- Colombia

                                    Reconstruccion tridimensional del anillo mitral

                                    ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                    Remodelacioacuten ventricular izquierda post IAM

                                    COAPSYS DEVICE

                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                    CLIP MITRAL

                                    Imagen Ecocardiografica antes y despues de

                                    anuloplastia del seno coronario

                                    (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                    with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                    with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                    young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                    asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                    J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                    • Slide 1
                                    • Slide 2
                                    • Slide 3
                                    • Slide 4
                                    • Slide 5
                                    • Slide 6
                                    • Slide 7
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                                    • Slide 43

                                      ACCAHA 2006 Guidelines for the Management of PatientsWith Valvular Heart DiseaseA Report of the American College of CardiologyAmerican Heart AssociationTask Force on Practice Guidelines (Writing Committee to Revise the 1998Guidelines for the Management of Patients With Valvular Heart Disease)

                                      Circulation August 1 2006

                                      MV repair is the operation of choice when the valve is suitable for repair and appropriate surgical skill and expertise are available This procedure preserves thepatientrsquos native valve without a prosthesis and therefore avoids the risk of chronic anticoagulation (except in patients in atrial fibrillation) or prosthetic valve failure late after surgery Additionally preservation of the mitral apparatus leads to better postoperative LV function and survival than in cases in which the apparatus is disrupted In most cases

                                      VS

                                      Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                                      bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                                      3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                                      4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                                      ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                                      VS

                                      Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                      Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                      Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                      Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                      VS

                                      Eur J Cardiothorac Surg 2010371039-1046

                                      Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                      A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                      Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                      VS

                                      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                      bull Lars G Svensson MD PhDa

                                      (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                      Sobrevida 83 62 43 86 63 45

                                      Libre de Re operacion

                                      94 94 95 92

                                      J Thorac Cardiovasc Surg 2008135885-893

                                      VS

                                      Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                      Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                      Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                      bull Lars G Svensson MD PhDa

                                      Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                      repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                      J Thorac Cardiovasc Surg 2008135885-893

                                      VS

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                      REPARO MITRALTECNICAS QUIRURGICAS

                                      HOJUELA POSTERIORRESECCION CUADRANGULAR

                                      TRASPOSICION DE CUERDAS TENDINEAS

                                      REIMPLATE MUSCULO PAPILAR

                                      RESECCION TRIANGULAR

                                      El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                      No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                      CONCLUSION

                                      El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                      Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                      CONCLUSION

                                      CONTROVERSIAS EN CIRUGIacuteA DE

                                      LA VALVULA MITRAL

                                      Dra Moacutenica RenterigraveaCali- Colombia

                                      Reconstruccion tridimensional del anillo mitral

                                      ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                      Remodelacioacuten ventricular izquierda post IAM

                                      COAPSYS DEVICE

                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                      CLIP MITRAL

                                      Imagen Ecocardiografica antes y despues de

                                      anuloplastia del seno coronario

                                      (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                      with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                      with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                      young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                      asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                      J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                        Class IbullMV surgery is recommended for the symptomatic patient with acute severe MR (Level of Evidence B)

                                        bullMV surgery is beneficial for patients with chronic severe MR and NYHA functional class II III or IVsymptoms in the absence of severe LV dysfunction(severe LV dysfunction is defined as ejection fractionless than 030) andor end-systolic dimension greaterthan 55 mm (Level of Evidence B)

                                        3 MV surgery is beneficial for asymptomatic patients with chronic severe MR and mild to moderate LV dysfunction ejection fraction 030 to 060 andor end-systolic dimension greater than or equal to 40mm (Level of Evidence B)

                                        4 MV repair is recommended over MV replacement inthe majority of patients with severe chronic MR who require surgery and patients should be referred to surgical centers experienced in MV repair Bonow et al ACCAHA Practice Guidelines (Level ofEvidence C)

                                        ACCAHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

                                        VS

                                        Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                        Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                        Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                        Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                        VS

                                        Eur J Cardiothorac Surg 2010371039-1046

                                        Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                        A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                        Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                        VS

                                        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                        bull Lars G Svensson MD PhDa

                                        (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                        Sobrevida 83 62 43 86 63 45

                                        Libre de Re operacion

                                        94 94 95 92

                                        J Thorac Cardiovasc Surg 2008135885-893

                                        VS

                                        Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                        Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                        Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                        bull Lars G Svensson MD PhDa

                                        Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                        repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                        J Thorac Cardiovasc Surg 2008135885-893

                                        VS

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                        REPARO MITRALTECNICAS QUIRURGICAS

                                        HOJUELA POSTERIORRESECCION CUADRANGULAR

                                        TRASPOSICION DE CUERDAS TENDINEAS

                                        REIMPLATE MUSCULO PAPILAR

                                        RESECCION TRIANGULAR

                                        El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                        No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                        CONCLUSION

                                        El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                        Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                        CONCLUSION

                                        CONTROVERSIAS EN CIRUGIacuteA DE

                                        LA VALVULA MITRAL

                                        Dra Moacutenica RenterigraveaCali- Colombia

                                        Reconstruccion tridimensional del anillo mitral

                                        ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                        Remodelacioacuten ventricular izquierda post IAM

                                        COAPSYS DEVICE

                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                        CLIP MITRAL

                                        Imagen Ecocardiografica antes y despues de

                                        anuloplastia del seno coronario

                                        (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                        with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                        with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                        young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                        asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                        J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                        • Slide 43

                                          Long-term outcomes after surgery for rheumatic mitral valve disease valve repair versus mechanical valve replacement

                                          Joon Bum Kima Hee Jung Kima Duk Hwan Moona Sung Ho Junga Suk Jung Chooa Cheol Hyun Chunga Hyun Songb Jae Wo Leea

                                          Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Songpa-gu Seoul 138-736 South Korea

                                          Conclusions When performed for selected patients MV repair had excellent durability comparable to mechanical valve replacement in rheumatic disease Both MV repair and replacement had comparable long-term clinical results therefore repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding

                                          VS

                                          Eur J Cardiothorac Surg 2010371039-1046

                                          Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                          A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                          Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                          VS

                                          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                          bull Lars G Svensson MD PhDa

                                          (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                          Sobrevida 83 62 43 86 63 45

                                          Libre de Re operacion

                                          94 94 95 92

                                          J Thorac Cardiovasc Surg 2008135885-893

                                          VS

                                          Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                          Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                          Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                          bull Lars G Svensson MD PhDa

                                          Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                          repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                          J Thorac Cardiovasc Surg 2008135885-893

                                          VS

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                          REPARO MITRALTECNICAS QUIRURGICAS

                                          HOJUELA POSTERIORRESECCION CUADRANGULAR

                                          TRASPOSICION DE CUERDAS TENDINEAS

                                          REIMPLATE MUSCULO PAPILAR

                                          RESECCION TRIANGULAR

                                          El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                          No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                          CONCLUSION

                                          El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                          Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                          CONCLUSION

                                          CONTROVERSIAS EN CIRUGIacuteA DE

                                          LA VALVULA MITRAL

                                          Dra Moacutenica RenterigraveaCali- Colombia

                                          Reconstruccion tridimensional del anillo mitral

                                          ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                          Remodelacioacuten ventricular izquierda post IAM

                                          COAPSYS DEVICE

                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                          CLIP MITRAL

                                          Imagen Ecocardiografica antes y despues de

                                          anuloplastia del seno coronario

                                          (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                          with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                          with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                          young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                          asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                          J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                            Valve Repair Improves the Outcome of Surgery for Mitral Regurgitation

                                            A Multivariate Analysis Maurice Enriquez-Sarano MD Hartzell V Schaff MD Thomas A Orszulak MD A Jamil Tajik MD Kent R Bailey PhD Robert L Frye MD From the Division of Cardiovascular Diseases and Internal Medicine (ME-S AJT RLF) Section of Cardiovascular Surgery (HVS TAO) and Section of Biostatistics (KRB) Mayo Clinic and Mayo Foundation Rochester Minn

                                            Conclusions Valve repair significantly improves postoperative outcome in patients with mitral regurgitation and should be the preferred mode of surgical correction The low operative mortality is an incentive for early surgery before ventricular dysfunction occurs

                                            VS

                                            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                            bull Lars G Svensson MD PhDa

                                            (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                            Sobrevida 83 62 43 86 63 45

                                            Libre de Re operacion

                                            94 94 95 92

                                            J Thorac Cardiovasc Surg 2008135885-893

                                            VS

                                            Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                            Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                            Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                            bull Lars G Svensson MD PhDa

                                            Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                            repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                            J Thorac Cardiovasc Surg 2008135885-893

                                            VS

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                            REPARO MITRALTECNICAS QUIRURGICAS

                                            HOJUELA POSTERIORRESECCION CUADRANGULAR

                                            TRASPOSICION DE CUERDAS TENDINEAS

                                            REIMPLATE MUSCULO PAPILAR

                                            RESECCION TRIANGULAR

                                            El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                            No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                            CONCLUSION

                                            El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                            Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                            CONCLUSION

                                            CONTROVERSIAS EN CIRUGIacuteA DE

                                            LA VALVULA MITRAL

                                            Dra Moacutenica RenterigraveaCali- Colombia

                                            Reconstruccion tridimensional del anillo mitral

                                            ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                            Remodelacioacuten ventricular izquierda post IAM

                                            COAPSYS DEVICE

                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                            CLIP MITRAL

                                            Imagen Ecocardiografica antes y despues de

                                            anuloplastia del seno coronario

                                            (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                            with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                            with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                            young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                            asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                            J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                              bull Lars G Svensson MD PhDa

                                              (70 )plusmn 12 antildeos (57 )plusmn 13 antildeos5a 10a 15a 5a 10a 15ordf

                                              Sobrevida 83 62 43 86 63 45

                                              Libre de Re operacion

                                              94 94 95 92

                                              J Thorac Cardiovasc Surg 2008135885-893

                                              VS

                                              Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                              Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                              Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                              bull Lars G Svensson MD PhDa

                                              Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                              repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                              J Thorac Cardiovasc Surg 2008135885-893

                                              VS

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                              REPARO MITRALTECNICAS QUIRURGICAS

                                              HOJUELA POSTERIORRESECCION CUADRANGULAR

                                              TRASPOSICION DE CUERDAS TENDINEAS

                                              REIMPLATE MUSCULO PAPILAR

                                              RESECCION TRIANGULAR

                                              El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                              No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                              CONCLUSION

                                              El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                              Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                              CONCLUSION

                                              CONTROVERSIAS EN CIRUGIacuteA DE

                                              LA VALVULA MITRAL

                                              Dra Moacutenica RenterigraveaCali- Colombia

                                              Reconstruccion tridimensional del anillo mitral

                                              ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                              Remodelacioacuten ventricular izquierda post IAM

                                              COAPSYS DEVICE

                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                              CLIP MITRAL

                                              Imagen Ecocardiografica antes y despues de

                                              anuloplastia del seno coronario

                                              (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                              with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                              with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                              young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                              asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                              J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                              • Slide 1
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                                              • Slide 42
                                              • Slide 43

                                                Valve repair versus valve replacement for degenerative mitral valve diseasebullMarc Gillinov MDa

                                                Eugene H Blackstone MDab Edward R Nowicki MDa Worawong

                                                Slisatkorn MDa Ghannam Al-Dossari MDa Douglas R Johnston MDa Kristopher M George MDa Penny L Houghtaling MSb Brian Griffin MDc Joseph F Sabik III Mda

                                                bull Lars G Svensson MD PhDa

                                                Conclusion It is reasonable to perform valve repair in elderly patients with complex degenerative mitral valve pathology because it can eliminate the need for anticoagulation and risk of prosthesis-related complications However when valve pathology is so complex that

                                                repair is infeasible this study demonstrates that valve replacement does not diminish long-term outcomes

                                                J Thorac Cardiovasc Surg 2008135885-893

                                                VS

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                REPARO MITRALTECNICAS QUIRURGICAS

                                                HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                TRASPOSICION DE CUERDAS TENDINEAS

                                                REIMPLATE MUSCULO PAPILAR

                                                RESECCION TRIANGULAR

                                                El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                CONCLUSION

                                                El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                CONCLUSION

                                                CONTROVERSIAS EN CIRUGIacuteA DE

                                                LA VALVULA MITRAL

                                                Dra Moacutenica RenterigraveaCali- Colombia

                                                Reconstruccion tridimensional del anillo mitral

                                                ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                Remodelacioacuten ventricular izquierda post IAM

                                                COAPSYS DEVICE

                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                CLIP MITRAL

                                                Imagen Ecocardiografica antes y despues de

                                                anuloplastia del seno coronario

                                                (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                  ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                  The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                  REPARO MITRALTECNICAS QUIRURGICAS

                                                  HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                  TRASPOSICION DE CUERDAS TENDINEAS

                                                  REIMPLATE MUSCULO PAPILAR

                                                  RESECCION TRIANGULAR

                                                  El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                  No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                  CONCLUSION

                                                  El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                  Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                  CONCLUSION

                                                  CONTROVERSIAS EN CIRUGIacuteA DE

                                                  LA VALVULA MITRAL

                                                  Dra Moacutenica RenterigraveaCali- Colombia

                                                  Reconstruccion tridimensional del anillo mitral

                                                  ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                  Remodelacioacuten ventricular izquierda post IAM

                                                  COAPSYS DEVICE

                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                  CLIP MITRAL

                                                  Imagen Ecocardiografica antes y despues de

                                                  anuloplastia del seno coronario

                                                  (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                  with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                  with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                  young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                  asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                  J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                    ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                    The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                    REPARO MITRALTECNICAS QUIRURGICAS

                                                    HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                    TRASPOSICION DE CUERDAS TENDINEAS

                                                    REIMPLATE MUSCULO PAPILAR

                                                    RESECCION TRIANGULAR

                                                    El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                    No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                    CONCLUSION

                                                    El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                    Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                    CONCLUSION

                                                    CONTROVERSIAS EN CIRUGIacuteA DE

                                                    LA VALVULA MITRAL

                                                    Dra Moacutenica RenterigraveaCali- Colombia

                                                    Reconstruccion tridimensional del anillo mitral

                                                    ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                    Remodelacioacuten ventricular izquierda post IAM

                                                    COAPSYS DEVICE

                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                    CLIP MITRAL

                                                    Imagen Ecocardiografica antes y despues de

                                                    anuloplastia del seno coronario

                                                    (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                    with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                    with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                    young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                    asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                    J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                      ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                      The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                      REPARO MITRALTECNICAS QUIRURGICAS

                                                      HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                      TRASPOSICION DE CUERDAS TENDINEAS

                                                      REIMPLATE MUSCULO PAPILAR

                                                      RESECCION TRIANGULAR

                                                      El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                      No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                      CONCLUSION

                                                      El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                      Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                      CONCLUSION

                                                      CONTROVERSIAS EN CIRUGIacuteA DE

                                                      LA VALVULA MITRAL

                                                      Dra Moacutenica RenterigraveaCali- Colombia

                                                      Reconstruccion tridimensional del anillo mitral

                                                      ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                      Remodelacioacuten ventricular izquierda post IAM

                                                      COAPSYS DEVICE

                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                      CLIP MITRAL

                                                      Imagen Ecocardiografica antes y despues de

                                                      anuloplastia del seno coronario

                                                      (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                      with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                      with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                      young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                      asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                      J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                        Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                        ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                        The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                        REPARO MITRALTECNICAS QUIRURGICAS

                                                        HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                        TRASPOSICION DE CUERDAS TENDINEAS

                                                        REIMPLATE MUSCULO PAPILAR

                                                        RESECCION TRIANGULAR

                                                        El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                        No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                        CONCLUSION

                                                        El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                        Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                        CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                        CONCLUSION

                                                        CONTROVERSIAS EN CIRUGIacuteA DE

                                                        LA VALVULA MITRAL

                                                        Dra Moacutenica RenterigraveaCali- Colombia

                                                        Reconstruccion tridimensional del anillo mitral

                                                        ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                        Remodelacioacuten ventricular izquierda post IAM

                                                        COAPSYS DEVICE

                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                        CLIP MITRAL

                                                        Imagen Ecocardiografica antes y despues de

                                                        anuloplastia del seno coronario

                                                        (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                        with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                        with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                        young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                        asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                        J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                          Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                          ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                          The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                          REPARO MITRALTECNICAS QUIRURGICAS

                                                          HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                          TRASPOSICION DE CUERDAS TENDINEAS

                                                          REIMPLATE MUSCULO PAPILAR

                                                          RESECCION TRIANGULAR

                                                          El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                          No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                          CONCLUSION

                                                          El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                          Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                          CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                          CONCLUSION

                                                          CONTROVERSIAS EN CIRUGIacuteA DE

                                                          LA VALVULA MITRAL

                                                          Dra Moacutenica RenterigraveaCali- Colombia

                                                          Reconstruccion tridimensional del anillo mitral

                                                          ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                          Remodelacioacuten ventricular izquierda post IAM

                                                          COAPSYS DEVICE

                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                          CLIP MITRAL

                                                          Imagen Ecocardiografica antes y despues de

                                                          anuloplastia del seno coronario

                                                          (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                          with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                          with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                          young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                          asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                          J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                            Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                            ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                            The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                            REPARO MITRALTECNICAS QUIRURGICAS

                                                            HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                            TRASPOSICION DE CUERDAS TENDINEAS

                                                            REIMPLATE MUSCULO PAPILAR

                                                            RESECCION TRIANGULAR

                                                            El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                            No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                            CONCLUSION

                                                            El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                            Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                            CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                            CONCLUSION

                                                            CONTROVERSIAS EN CIRUGIacuteA DE

                                                            LA VALVULA MITRAL

                                                            Dra Moacutenica RenterigraveaCali- Colombia

                                                            Reconstruccion tridimensional del anillo mitral

                                                            ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                            Remodelacioacuten ventricular izquierda post IAM

                                                            COAPSYS DEVICE

                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                            CLIP MITRAL

                                                            Imagen Ecocardiografica antes y despues de

                                                            anuloplastia del seno coronario

                                                            (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                            with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                            with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                            young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                            asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                            J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                                            • Slide 1
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                                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                              Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                              ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                              The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                              REPARO MITRALTECNICAS QUIRURGICAS

                                                              HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                              TRASPOSICION DE CUERDAS TENDINEAS

                                                              REIMPLATE MUSCULO PAPILAR

                                                              RESECCION TRIANGULAR

                                                              El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                              No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                              CONCLUSION

                                                              El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                              Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                              CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                              CONCLUSION

                                                              CONTROVERSIAS EN CIRUGIacuteA DE

                                                              LA VALVULA MITRAL

                                                              Dra Moacutenica RenterigraveaCali- Colombia

                                                              Reconstruccion tridimensional del anillo mitral

                                                              ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                              Remodelacioacuten ventricular izquierda post IAM

                                                              COAPSYS DEVICE

                                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                              CLIP MITRAL

                                                              Imagen Ecocardiografica antes y despues de

                                                              anuloplastia del seno coronario

                                                              (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                              with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                              with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                              young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                              asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                              J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                Mitral valve replacement versus repair propensity-adjusted survival and quality-of-life analysisJokinen JJ Hippelaumlinen MJ Pitkaumlnen OA Hartikainen JEDepartment of Cardiothoracic Surgery Helsinki University Hospital Helsinki Finland

                                                                ConclusionsSurvival is longer after MVP than after MVR The quality of life of MVP and MVR patients does not differ from each other In terms of most quality-of-life variables patients who undergo mitral valve operations cope similarly to an age- and sex-matched reference population Only the scores reflecting energy and mobility were lower in the patients who were operated on than in the reference population

                                                                The Annals of Thoracic Surgery Volume 84 Issue 2 August 2007 Paes 451-458

                                                                REPARO MITRALTECNICAS QUIRURGICAS

                                                                HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                                TRASPOSICION DE CUERDAS TENDINEAS

                                                                REIMPLATE MUSCULO PAPILAR

                                                                RESECCION TRIANGULAR

                                                                El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                                No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                CONCLUSION

                                                                El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                                Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                                CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                CONCLUSION

                                                                CONTROVERSIAS EN CIRUGIacuteA DE

                                                                LA VALVULA MITRAL

                                                                Dra Moacutenica RenterigraveaCali- Colombia

                                                                Reconstruccion tridimensional del anillo mitral

                                                                ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                                Remodelacioacuten ventricular izquierda post IAM

                                                                COAPSYS DEVICE

                                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                CLIP MITRAL

                                                                Imagen Ecocardiografica antes y despues de

                                                                anuloplastia del seno coronario

                                                                (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

                                                                • Slide 1
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                                                                  REPARO MITRALTECNICAS QUIRURGICAS

                                                                  HOJUELA POSTERIORRESECCION CUADRANGULAR

                                                                  TRASPOSICION DE CUERDAS TENDINEAS

                                                                  REIMPLATE MUSCULO PAPILAR

                                                                  RESECCION TRIANGULAR

                                                                  El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                                  No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                  CONCLUSION

                                                                  El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                                  Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                                  CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                  CONCLUSION

                                                                  CONTROVERSIAS EN CIRUGIacuteA DE

                                                                  LA VALVULA MITRAL

                                                                  Dra Moacutenica RenterigraveaCali- Colombia

                                                                  Reconstruccion tridimensional del anillo mitral

                                                                  ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                                  Remodelacioacuten ventricular izquierda post IAM

                                                                  COAPSYS DEVICE

                                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                  CLIP MITRAL

                                                                  Imagen Ecocardiografica antes y despues de

                                                                  anuloplastia del seno coronario

                                                                  (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                  CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                  with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                  with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                  young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                  asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                  J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                    El Reparo Valvular Mitral (RVM) es Superior Al Cambio Valvular Mitral (CVM) Por La Preservacioacuten De Todo El Aparato Sub valvular Que Garantiza La Competencia Mitral Preserva La Funcioacuten Del VI Y Aumenta La Sobrevida

                                                                    No hay diferencias en tegraverminos de calidad de vida entre las 2 tegravecnicas si no es necesaria la anticoagulacion cronica con warfarina

                                                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                    CONCLUSION

                                                                    El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                                    Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                                    CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                    CONCLUSION

                                                                    CONTROVERSIAS EN CIRUGIacuteA DE

                                                                    LA VALVULA MITRAL

                                                                    Dra Moacutenica RenterigraveaCali- Colombia

                                                                    Reconstruccion tridimensional del anillo mitral

                                                                    ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                                    Remodelacioacuten ventricular izquierda post IAM

                                                                    COAPSYS DEVICE

                                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                    CLIP MITRAL

                                                                    Imagen Ecocardiografica antes y despues de

                                                                    anuloplastia del seno coronario

                                                                    (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                    CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                    with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                    with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                    young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                    asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                    J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                      El efeecto benefico de la PVM versus el CVM en terminos de sobrevida se pierde en pacientes mayores de 70 antildeos por lo que cualquiera de las dos tecnicas utilizadas es aceptable en este grupo de edad

                                                                      Debe procurarse en todo paciente con CVM la preservacion del aparato subvalvular posterior

                                                                      CIRUGIA VALVULAR MITRAL CAMBIO VS REPARO

                                                                      CONCLUSION

                                                                      CONTROVERSIAS EN CIRUGIacuteA DE

                                                                      LA VALVULA MITRAL

                                                                      Dra Moacutenica RenterigraveaCali- Colombia

                                                                      Reconstruccion tridimensional del anillo mitral

                                                                      ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                                      Remodelacioacuten ventricular izquierda post IAM

                                                                      COAPSYS DEVICE

                                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                      CLIP MITRAL

                                                                      Imagen Ecocardiografica antes y despues de

                                                                      anuloplastia del seno coronario

                                                                      (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                      CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                      with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                      with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                      young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                      asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                      J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                        CONTROVERSIAS EN CIRUGIacuteA DE

                                                                        LA VALVULA MITRAL

                                                                        Dra Moacutenica RenterigraveaCali- Colombia

                                                                        Reconstruccion tridimensional del anillo mitral

                                                                        ENFERMEDAD VALVULAR MITRAL DE ORIGEN ISQUEMICO

                                                                        Remodelacioacuten ventricular izquierda post IAM

                                                                        COAPSYS DEVICE

                                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                        CLIP MITRAL

                                                                        Imagen Ecocardiografica antes y despues de

                                                                        anuloplastia del seno coronario

                                                                        (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                        CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                        with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                        with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                        young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                        asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                        J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                          Remodelacioacuten ventricular izquierda post IAM

                                                                          COAPSYS DEVICE

                                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                          CLIP MITRAL

                                                                          Imagen Ecocardiografica antes y despues de

                                                                          anuloplastia del seno coronario

                                                                          (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                          CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                          with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                          with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                          young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                          asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                          J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                            COAPSYS DEVICE

                                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                            CLIP MITRAL

                                                                            Imagen Ecocardiografica antes y despues de

                                                                            anuloplastia del seno coronario

                                                                            (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                            CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                            with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                            with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                            young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                            asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                            J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                              CLIP MITRAL

                                                                              Imagen Ecocardiografica antes y despues de

                                                                              anuloplastia del seno coronario

                                                                              (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                              CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                              with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                              with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                              young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                              asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                              J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                                Imagen Ecocardiografica antes y despues de

                                                                                anuloplastia del seno coronario

                                                                                (C) CARILLON (Cardiac DimensionsKirkland WA) (D) MONARC (Edwards Lifesciences Irvine CA)(E) Percutaneous Transvenous Mitral Annuloplasty Device (Viacor Inc Wilmington MA)

                                                                                CORRECCION PERCUTANEA DE LA INSUFICIENCIA MITRAL

                                                                                with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                                with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                                young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                                asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                                J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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                                                                                  with congenital MS who have symptoms (NYHA functional class III or IV) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                                  with congenital MS who have mild symptoms (NYHA functional class II) and mean MV gradient greater than 10 mm Hg on Doppler echocardiography (Level of Evidence C)

                                                                                  young adult with congenital MS with pulmonary artery systolic pressure 50 mm Hg or greater and a mean MV gradient greater than or equal to 10 mm Hg (Level of Evidence C)

                                                                                  asymptomatic adolescent or young adult with congenital MS and new-onset atrial fibrillation or multiple systemic emboli while receiving adequate anticoagulation (Level of Evidence C

                                                                                  J Am Coll Cardiol 2006 48598-675 doi101016jjacc200605030

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