Textus Epithelium

TEXTUS EPITHELIUM

PRESENTED FOR BSHB BLOCK TA. 2011/2012

KOMPETENSI

1. Mampu menjelaskan definisi textus epitelium

2. Mampu menyebutkan fungsi textus epitelium

3. Mampu menyebutkan macam-macam textus epithelium.

4. Mampu menjelaskan bagian-bagian textus epitelium.

TEXTUS EPITHELIUM ????

Jaringan avaskuler, tersusun atas beberapa sel

APA ???

MELAPISIpermukaan luar tubuh

permukaan dalam rongga tubuh

Rongga tubuh yg berhubungan dgn permukaan luar tubuh seperti saluran pernafasan, saluran genitourinari

KLASIFIKASI JARINGAN EPITEL

1. Berdasarkan jumlah lapisan sel

a. Selapis SIMPLE atau SIMPLEX

b. Berlapis STRATIFIED atau STRATIFICATUM

2. Berdasarkan bentuknya SQUAMOUS SQUAMOSUM PIPIH CUBOIDAL CUBOIDEUM KUBUS COLUMNAR COLUMNARE SILINDRIS

TEXTUS EPITHELIUM SIMPLEX

TEXTUS EPITHELIUM STRATIFICATUM

TEXTUS EPITHELIUM KHUSUS

1. TEXTUS EPITHELIUM PSEUDO-STRATIFICATUM

TEXTUS EPITHELIUM KHUSUS

2. TEXTUS EPITHELIUM TRANSITIONAL

Spesific names are given to epithelium in certain locations :

1. Endothelium is epithelial lining of the blood and lymphatic vessels

2. Endocardium is the epithelial lining of ventricles and atria of the heart

3. Mesothelium is the epithelium that lines the walls and covers the contents of the closed cavities of the body (i.e. abdominal, pericardial and pleural cavities)

A.Cell JunctionsB.Free surface / apical

domain, lateral domain and basal domain

C.Basement membrane

KARAKTERISTIK DASAR SEL-SEL PENYUSUN JARINGAN PITEL

POLARITAS SEL

• Epithelial cells exhibit distinct polarity. They have an apical domain, a lateral domain, and a basal domain.

• Spesific biochemical characteristics are associated with each cell surface

• These characteristics and the geometric arrangements of the cells in the epithelium determine the functional polarity of all 3 cell domains.

MODIFIKASI DOMAIN APIKAL

1. Microvilli, cytoplasmic processes

that extend from the cell surface

2. Steroecilia (stereovilli), microvilli of

unusual length

3. Cilia, motile cytoplasmic processes

IKATAN ANTAR SEL PADA LATERAL DOMAIN:1. Occluding Junctions

– zonula occludens (occludin,claudins,JAM)

2. Anchoring junctions – zonula adherens- macula adherens / desmosome

3. Communicating junctions / gap junctions / nexuses

BASAL DOMAIN, IKATAN ANTARA SEL DGN MATRIKS EKSTRASELULER

1.Basement membrane

2.Cell to extracellular matrix junctions :

Anchoring junctions : Focal adhesions &

Hemidesmosomes

3.Basal cell membrane infoldings

KOMPONEN DOMAIN BASAL, SPESIALISASI PADA IKATAN SEL- MATRIKS EKSTRA SELULER

1.Basement membrane

2.Cell to extracellular matrix junctions :

Anchoring junctions : Focal adhesions &

Hemidesmosomes

3.Basal cell membrane infoldings

FUNGSI TEXTUS EPITELIUM

FUNGSI

SEKRESI

ABSORBSITRANSPORT ANTAR SELPROTEK

SIRESEPTOR

1. FUNGSI SEKRETORI

• Berperan dlm proses sekresi produk-produk kelenjar.

Bagian sekresi darisuatukelenjar dan duktusnya tersusun atas jar. Epitel.

2. FUNGSI ABSORBSI

• Berperan dlm proses absorbbsi.• Ditemukan pd Epitel columnare pd usus halus

3. FUNGSI TRANSPORT

a. transport material intersel melalui silia.

b. Transport material dari jaringan epitelium ke jaringan ikat (atau sebaliknya)

4. FUNGSI PROTEKSI

• Sebagai pelindung• Seperti pada textus epitheliasis squamous

stratificatum di epidermis.

5. FUNGSI RESEPTOR

• Berperan dlm proses penerimaan dan penghantar rangsang eksternal.

• Seperti pada indera perasa pada lidah, penghidu pada mukosa nasal, retina pada mata,

Histogenesis of epithelium

• The three germ layers in the developing embryo contribute to the formation of the various epithelia

1. Ectodermal derivatives

2. Mesodermal derivatives

3. Endodermal derivatives

Ectodermal derivatives

• Surface ectoderm

- epidermis

- cornea & lens epithelia of the eye

- enamel organ & enamel of the teeth

- components of the inner ear

- anterior lobe of pituitary gland adenohypophysis

• Neuroectoderm

- neural tube &its derivatives (CNS, sensoryEpt, etc)

- neural crest &its derivatives

Mesodermal derivatives

• Epithelium of the kidney and the gonads

• Mesothelium• Endothelium• Adrenal cortex• Genital duct epithelium

ENDODERMAL DERIVATIVES

Respiratory system epitheliumAlimentary canal epitheliumExtramural digestive gland

epitheliumThyroid, parathyroid and thymus

gland epithelial componentsLining epithelium of the tympanic

cavity and auditory (eustachian) tubes

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