TEXTUS EPITHELIUM PRESENTED FOR BSHB BLOCK TA. 2011/2012
TEXTUS EPITHELIUM
PRESENTED FOR BSHB BLOCK TA. 2011/2012
KOMPETENSI
1. Mampu menjelaskan definisi textus epitelium
2. Mampu menyebutkan fungsi textus epitelium
3. Mampu menyebutkan macam-macam textus epithelium.
4. Mampu menjelaskan bagian-bagian textus epitelium.
TEXTUS EPITHELIUM ????
Jaringan avaskuler, tersusun atas beberapa sel
APA ???
MELAPISIpermukaan luar tubuh
permukaan dalam rongga tubuh
Rongga tubuh yg berhubungan dgn permukaan luar tubuh seperti saluran pernafasan, saluran genitourinari
KLASIFIKASI JARINGAN EPITEL
1. Berdasarkan jumlah lapisan sel
a. Selapis SIMPLE atau SIMPLEX
b. Berlapis STRATIFIED atau STRATIFICATUM
2. Berdasarkan bentuknya SQUAMOUS SQUAMOSUM PIPIH CUBOIDAL CUBOIDEUM KUBUS COLUMNAR COLUMNARE SILINDRIS
TEXTUS EPITHELIUM SIMPLEX
TEXTUS EPITHELIUM STRATIFICATUM
TEXTUS EPITHELIUM KHUSUS
1. TEXTUS EPITHELIUM PSEUDO-STRATIFICATUM
TEXTUS EPITHELIUM KHUSUS
2. TEXTUS EPITHELIUM TRANSITIONAL
Spesific names are given to epithelium in certain locations :
1. Endothelium is epithelial lining of the blood and lymphatic vessels
2. Endocardium is the epithelial lining of ventricles and atria of the heart
3. Mesothelium is the epithelium that lines the walls and covers the contents of the closed cavities of the body (i.e. abdominal, pericardial and pleural cavities)
A.Cell JunctionsB.Free surface / apical
domain, lateral domain and basal domain
C.Basement membrane
KARAKTERISTIK DASAR SEL-SEL PENYUSUN JARINGAN PITEL
POLARITAS SEL
• Epithelial cells exhibit distinct polarity. They have an apical domain, a lateral domain, and a basal domain.
• Spesific biochemical characteristics are associated with each cell surface
• These characteristics and the geometric arrangements of the cells in the epithelium determine the functional polarity of all 3 cell domains.
MODIFIKASI DOMAIN APIKAL
1. Microvilli, cytoplasmic processes
that extend from the cell surface
2. Steroecilia (stereovilli), microvilli of
unusual length
3. Cilia, motile cytoplasmic processes
IKATAN ANTAR SEL PADA LATERAL DOMAIN:1. Occluding Junctions
– zonula occludens (occludin,claudins,JAM)
2. Anchoring junctions – zonula adherens- macula adherens / desmosome
3. Communicating junctions / gap junctions / nexuses
BASAL DOMAIN, IKATAN ANTARA SEL DGN MATRIKS EKSTRASELULER
1.Basement membrane
2.Cell to extracellular matrix junctions :
Anchoring junctions : Focal adhesions &
Hemidesmosomes
3.Basal cell membrane infoldings
KOMPONEN DOMAIN BASAL, SPESIALISASI PADA IKATAN SEL- MATRIKS EKSTRA SELULER
1.Basement membrane
2.Cell to extracellular matrix junctions :
Anchoring junctions : Focal adhesions &
Hemidesmosomes
3.Basal cell membrane infoldings
FUNGSI TEXTUS EPITELIUM
FUNGSI
SEKRESI
ABSORBSITRANSPORT ANTAR SELPROTEK
SIRESEPTOR
1. FUNGSI SEKRETORI
• Berperan dlm proses sekresi produk-produk kelenjar.
Bagian sekresi darisuatukelenjar dan duktusnya tersusun atas jar. Epitel.
2. FUNGSI ABSORBSI
• Berperan dlm proses absorbbsi.• Ditemukan pd Epitel columnare pd usus halus
3. FUNGSI TRANSPORT
a. transport material intersel melalui silia.
b. Transport material dari jaringan epitelium ke jaringan ikat (atau sebaliknya)
4. FUNGSI PROTEKSI
• Sebagai pelindung• Seperti pada textus epitheliasis squamous
stratificatum di epidermis.
5. FUNGSI RESEPTOR
• Berperan dlm proses penerimaan dan penghantar rangsang eksternal.
• Seperti pada indera perasa pada lidah, penghidu pada mukosa nasal, retina pada mata,
Histogenesis of epithelium
• The three germ layers in the developing embryo contribute to the formation of the various epithelia
1. Ectodermal derivatives
2. Mesodermal derivatives
3. Endodermal derivatives
Ectodermal derivatives
• Surface ectoderm
- epidermis
- cornea & lens epithelia of the eye
- enamel organ & enamel of the teeth
- components of the inner ear
- anterior lobe of pituitary gland adenohypophysis
• Neuroectoderm
- neural tube &its derivatives (CNS, sensoryEpt, etc)
- neural crest &its derivatives
Mesodermal derivatives
• Epithelium of the kidney and the gonads
• Mesothelium• Endothelium• Adrenal cortex• Genital duct epithelium
ENDODERMAL DERIVATIVES
Respiratory system epitheliumAlimentary canal epitheliumExtramural digestive gland
epitheliumThyroid, parathyroid and thymus
gland epithelial componentsLining epithelium of the tympanic
cavity and auditory (eustachian) tubes
REVIEW
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