Hepatology 2000; 31: 756-762 Jean-François Boivin September 29th, 2010 1.

Hepatology 2000; 31: 756-762

Jean-François Boivin

September 29th, 20101

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CASES CONTROLS

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CASES CONTROLS

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CASES CONTROLS

INHALED YES

ON

758 1,039

63% x 21% x 758 = 1,039 = 478 218

280 821

ODDS RATIO =

478 x 821 = 6.4 218 x 280

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Globe and Mail 10 September 2010

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New England Journal of Medicine 1999; 340: 603-608

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Archives of General Psychiatry 2010; 67: 889-894

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Robert H. Friss. Epidemiology for Public Heath Practice (2009); 368-36922

Personality Disorders and Suicide

Personality disorders are estimated to have been present in 30% of completed suicides and 40% of attempted suicides. Suicide occurs disproportionately in cluster B personality disorders. The rates of completed suicide in patients with borderline and antisocial personality disorders are 8% to 10% and 5%, respectively. Patients with borderline personality disorder have very high rates of suicide attempts (60%-75%).

Self-injurious and self-mutilating behaviors are common in borderline personality disorder (e.g., cutting oneself) but much of the time do not represent suicide attempts. Cluster C personality disorders account for about 10% of completed suicides, and cluster A personality disorders account for less than 1% of completed suicides.

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Personality Disorders and Suicide

Personality disorders are estimated to have been present in 30% of completed suicides and 40% of attempted suicides. Suicide occurs disproportionately in cluster B personality disorders. The rates of completed suicide in patients with borderline and antisocial personality disorders are 8% to 10% and 5%, respectively. Patients with borderline personality disorder have very high rates of suicide attempts (60%-75%).

Self-injurious and self-mutilating behaviors are common in borderline personality disorder (e.g., cutting oneself) but much of the time do not represent suicide attempts. Cluster C personality disorders account for about 10% of completed suicides, and cluster A personality disorders account for less than 1% of completed suicides.

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X 1% =

X 1/1000 =

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16%

4%

Risk in population = 100,000 = 9% 1,000,000

Relative risk = 16% ÷ 4% = 4

Population risk difference = 9% - 4% = 5%

Risk difference = 16% - 4% = 12%

Etiologic fraction

(16% - 4%) ÷ 16% = 0.75

note:

(relative risk -1) ÷ relative risk =(4 -1) ÷ 4 = 0.75

Population etiologic fraction

(9% - 4%) ÷ 9% = 0.56

note:

(relative risk -1) x % smokers in cases relative risk

= 4 - 1 x 75,000 = 0.56 4 100,000

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