BASI MOLECOLARI DELLAZIONE DEL FARMACO BIOTECNOLOGIE FARMACOLOGICHE LEZIONE 12 In vivo imaging CORSO DI LAUREA SPECIALISTICA IN BIOTECNOLOGIE DEL FARMACO.

BASI MOLECOLARI DELL’AZIONE DEL FARMACO

BIOTECNOLOGIE FARMACOLOGICHE

LEZIONE 12In vivo imaging

CORSO DI LAUREA SPECIALISTICA IN BIOTECNOLOGIE DEL FARMACO

Adriana Maggi

Target identification and

validation with reporter mice

Maggi and Ciana NRDD, 2005

MOLECULAR IMAGING 2007

THE AVAILABLE TOOLS

2/06

MULTI-MODALITY MOLECULAR IMAGING IN LIVING SMALL ANIMALS

Functional Magnetic Nuclear Resonance

Optical imagingBioluminescence

Ultrasound

MicroPETPositron emission tomography

Nuclear imaging

Micro SPECTsingle-photon emission

computerized tomography

2/06

Fluorescence

a2/06

MOLECULAR IMAGING

TO REVISIT ANIMAL EXPERIMENTATION

IN THE RESPECT OF ANIMAL SUFFERING

PARTICULARLY, IN PHARMACOLOGICAL RESEARCH!

ONE PICTURE IS WORTH TEN THOUSAND WORDS(Frederic Barnhard 1927)

2/06