AD Lab Andrews-Dalkilic Data Exploration. AD Lab Outline Architecture What is Bioinformatics? Explore some bioinformatics problems and tools Talk about.
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AD Lab
Andrews-Dalkilic
Data Exploration
AD Lab
Outline
Architecture
What is Bioinformatics?
Explore some bioinformatics problems and tools
Talk about what’s in store for us
AD Lab
Architecture
KnowledgeBase
RULES
Working MemoryFACTS
Explanation KnowledgeAcquisition
INFERENCEENGINE
AGENDA
UI
AD Lab
Architecture
KnowledgeAcquisition
A (semi)automatic way to add domain knowledge (rules) without having to be a programmer
We can create rules—but virtually no facility to explain how and why.
AD Lab
Architecture
FactoidsRule-based Systems
Rules
Post ProductionEfficient Pattern
Matching
Inference Engine
RHS Execution
Conflict ResolutionMarkov
ReteBayesian
AD Lab
Architecture
Post Production
AD Lab
Architecture
Premises (facts)
Axiomization & Inference Rules • build• tear apart
Bertrand Russell said, ``The point of philosophy is to start with something so simple as not to seem worth stating, and to end with something so paradoxical that no one will believe it.''
AD Lab
Architecture
Premises (facts)
Questions:Are these facts consistent? existing systems
Is this model consistent with the data?existing systems
AD Lab
Architecture
Axiomization & Rules• build• tear apart
Axiomization is meta-language over the facts
Any new facts are consistent with existing factsNo “new” facts can be found…
AD Lab
Architecture
Premises (facts)
Axiomization & Inference Rules
Querying (with a new [partial] fact)What in my database makes my fact true?
What is known about my fact?
AD Lab
AD Lab
Bon Voyage
Summary1st pass—deduction (simple)2nd pass—fuzzy 3rd Bayesian belief network
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