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What is the mechanism of store-operated Ca2+ entry? Measuring [Ca2+]ER and ICRAC in single cells Miyawaki et al, 1999 The ER sensor for CRAC channel activation has low Ca2+…
Slide 1 Zhen Shi June 2, 2010 Journal Club Introduction Most disease-causing mutations are thought to confer radical changes to proteins (Wang and Moult, 2001; Botstein and…