Slide 1Assembly reflects evolution of protein complexes Emmanuel D. Levy, Elisabetta Boeri Erba, Carol V. Robinson & Sarah A. Teichmann 2008/8/8 zhen JC Slide 2 Most…

Slide 1Prior Knowledge Driven Causality Analysis in Gene Regulatory Network Discovery Authors: Shun Yao, Shinjae Yoo, Dantong Yu Stony Brook University Computational Science…

1.Protein Arrays (Biosurfaces for Proteome Research) 2. Outline Protein Analysis – Introduction  Why ?  How ? New Protein Analysis Tools  Protein Arrays  SELDI…

Slide 1 Sequence analysis FINDING STRUCTURES AND PATTERNS Slide 2 combinatorics Like a language composed from an alphabet, the letters are the basic building blocks – Letters…

Slide 1 Mass-action equilibrium and non-specific interactions in protein interaction networks Sergei Maslov Brookhaven National Laboratory Slide 2 Living cells contain crowded…

Slide 1 Modularity in Biological networks Slide 2  Hypothesis: Biological function are carried by discrete functional modules.  Hartwell, L.-H., Hopfield, J. J., Leibler,…

Slide 1 Introduction to biological networks Slide 2 protein-gene interactions protein-protein interactions PROTEOME GENOME Citrate Cycle METABOLISM Bio-chemical reactions…

Slide 1 Graph, Search Algorithms Ka-Lok Ng Department of Bioinformatics Asia University Slide 2 2 Content How to characterize a biology network ? – Graph theory, topological…

Slide 1 Nothing in (computational) biology makes sense except in the light of evolution after Theodosius Dobzhansky (1970) Slide 2 A brief history and some central principles…

Slide 1 Enzymes and enzyme kinetics Slide 2 enzyme "in yeast" proteins and catalysts 1860: L. Pasteur "fermentation catalyzed by enzymes" 1897: E. Buchner…