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Documents FRAGMENT- BASED DRUG DESIGN Yemane Mengistu Michigan State University January 30, 2008.

Slide 1 Slide 2 FRAGMENT- BASED DRUG DESIGN Yemane Mengistu Michigan State University January 30, 2008 Slide 3 Annual Research and Development Expense Expense ($ Billions)…

Documents Diagnosis. Barium studies demonstrate the primary lesion and reveal a synchronous cancer elsewhere.....

Slide 1Diagnosis Slide 2 Barium studies demonstrate the primary lesion and reveal a synchronous cancer elsewhere in the colon Slide 3 Annular constricting or napkin-ring…

Health & Medicine Pharmacology mechanisms flash cards

1. 1binds receptor to allow Na and K to diffuse downtheir gradient nicotine/Ach on nicotinic receptorsbinds M2 (K channel and cAMP) inthe heart bethanecholbinds M3 (IP3/DAG)…

Documents Antimetabolites

DR. F. O. WANGO Antimetabolites act on nucleotide and nucleic acd synthesis Methotrexate is an example. It is folic acid antagonist and binds to the active site of dihydrofolate…

Documents 090513 Nucleic Acid Fulton

SECTION 9 Nucleic Acid Metabolism CONTACT INFORMATION Tracy Fulton, PhD (email) OBJECTIVES • Describe the difference between a pyrimidine and a purine base, discern a nucleoside…

Documents Diarrhea WHO Definition: The passage of more than 3 unformed stools in 24 hours. Or Frequent passage...

Slide 1 Slide 2 Diarrhea WHO Definition: The passage of more than 3 unformed stools in 24 hours. Or Frequent passage of loose stools with urgency. Slide 3 NCI Grading of…

Documents Final Exam Mon 8 am. Reduction of ribonucleotides to deoxyribonucleotides by ribonucleotide...

Slide 1 Final Exam Mon 8 am Slide 2 Reduction of ribonucleotides to deoxyribonucleotides by ribonucleotide reductase. Slide 3 FIGURE 22-40a Ribonucleotide reductase. (a)…

Documents Selected topics in molecular biology Review session Nov. 26, 2007.

Slide 1 Selected topics in molecular biology Review session Nov. 26, 2007 Slide 2 All nucleotides have a common structure Slide 3 There are five principal bases in nucleic…

Documents PRPP synthetase Nucleoside phosphorylases Phosphoribosyl transferases.

Slide 1 Slide 2 Slide 3 PRPP synthetase Nucleoside phosphorylases Phosphoribosyl transferases Slide 4 Slide 5 The committed step of de novo purine nucleotide biosynthesis…

Documents FOLATE, VITAMIN B12 and INHIBITORS Katzung (10th ed.) Chapter 33, pg. 531-536.

Slide 1 FOLATE, VITAMIN B12 and INHIBITORS Katzung (10th ed.) Chapter 33, pg. 531-536 Slide 2 CRITICAL FACTS 1.Folate and vitamin B12 are required for DNA synthesis and for…