You have worked for 2 years to isolate a gene involved in axon guidance. You sequence the cDNA clone that contains axon guidance activity. What do you do next? BLAST Methods…

Homology bird wing bat wing human arm by Bob Friedman homology vs analogy   Homology (shared ancestry) versus  Analogy (convergent evolution) A priori sequences…

Sequence comparison and database search Effect of gap penalty on Local Alignment Score: 161 at (seq1)[2..36] : (seq2)[53..90] 2 ASTV----TSCLEPTEVFMDLWPEDHSNWQELSPLEPSD ||…

DNA序列分析 David Shiuan Department of Life Science Institute of Biotechnology and Interdisciplinary Program of Bioinformatics National Dong Hwa University DNA序列分析…

General nucleic acid Sequence databases EMBL:(European Molecular Biology Laboratory) http://www.ebi.ac.uk/Information/ GenBank: NCBI (National Center for Biotechnology Information)…

Biology 4900 Biocomputing Chapter 4 BLAST BLAST BLAST allows user to search a sequence (the query) against millions of sequences in the NCBI database (the target). Global…

BLAST Introduction to Bioinformatics Anthony Nguyen BLAST - why? Sequence alignments provide a powerful way to compare novel sequences with previously characterized genes.…

PowerPoint Presentation - MCB 5472 MCB 5472 Blast, Psi BLAST, Perl: Arrays, Loops J. Peter Gogarten Office: BPB 404 phone: 860 486-4061, Email: [email protected] 1 homology…