1. Post-Transcriptional Modification The mRNA transcript synthesized by RNA polymerase II is modified in eukaryotes. 2. Steps of mRNA Processing 5’ Capping 3’ polyadenylation…

Slide 1 Chapter 15: Post-transcriptional events II: Capping and polyadenylation Cap structure Slide 2 Slide 3 a. a phosphohydrolysis removes the terminal phosphate from a…

Slide 1 RNA processing #1 Making ends of RNA Slide 2 Types of RNA processing A) Cutting and trimming to generate ends: –rRNA, tRNA and mRNA B) Covalent modification: –Add…

Slide 1 Chapter 12: Synthesis and Processing of RNA Copyright © Garland Science 2007 Slide 2 Genome expression includes 2 steps Initiation of transcription. Assembly of…

Chapter 1 DNA Structure & Gene Expression Structure of DNA, RNA, and polypeptides DNA & RNA are long polymers of nucleotides - nitrogenous bases – purines, pyrimidines…

Noise in gene expression networks? Ramu Anandakrishnan March 14, 2006 Blah .. Blah .. Blah .. Blah .. Shut up guys! I can’t hear what DNA it telling me to do. .. Rosenfeld…

Chapter 15: Post-transcriptional events II: Capping and polyadenylation Cap structure a. a phosphohydrolysis removes the terminal phosphate from a pre-mRNA; b. a guanylyl…

Chapter 1 DNA Structure & Gene Expression Structure of DNA, RNA, and polypeptides DNA & RNA are long polymers of nucleotides - nitrogenous bases – purines, pyrimidines…

Noise in gene expression networks? Ramu Anandakrishnan March 14, 2006 Blah .. Blah .. Blah .. Blah .. Shut up guys! I can’t hear what DNA it telling me to do. .. Rosenfeld…

RNA-Seq technology and it's application on dosage compensation between the X chromosome and autosomes in mammals 2011-12-05 Outline RNA-Seq: technologies and it's…