Slide 1 N-Acetylgalactosamine (GalNAc) N-Acetylglucosamine (GlcNAc) Mannose (Man) Fucose (Fuc) Xylose (Xyl) Sialic acid (sia) Glucuronic acid (GlcA) Galactose(Gal) Glucose…

Slide 1 ATM, Ataxia Telangiectasia, & Cancer Slide 2 Ataxia Telangiectasia Characterized by: Cerebellar deterioration Oculocutaneous telangiectasia Immunodeficiency Genomic…

Slide 1 Transport Inference Parser: Inferring Transport Reactions from Protein Data for PGDBs Slide 2 Running the Transport Inference Parser 1. Run Pathway Tools. 2. Make…

Transport Identification Parser: Inferring Transport Reactions from Protein Data for PGDBs Thomas J Lee, Peter Karp, AIC BRG Ian Paulsen consulting Running the Transport…

Chapter 6 Protein Function: Enzymes Part 2 Enzymes, Part 2 Chemical mechanisms of catalysis: Chymotrypsin Multi-substrate enzyme reaction kinetics Reversible enzyme inhibitors…

Deriving Kinetic Parameters & Rate Equations for Multi-Substrate Systems References for Multi-Substrate Enzyme Kinetics On-line: Dr. Peter Birch, University of Paisley…

ENZYMES ENZYMES are biological catalyst are mostly proteinaceous in nature, but RNA was an early biocatalyst are powerful and highly specific catalysts carbonic anhydrase…

Enzyme kinetics 1 Enzyme kinetics Dihydrofolate reductase from E. coli with its two substrates dihydrofolate (right) and NADPH (left), bound in the active site. The protein…

Transport Inference Parser: Inferring Transport Reactions from Protein Data for PGDBs Running the Transport Inference Parser 1. Run Pathway Tools. 2. Make the organism of…

Slide 1 Expanding the Pool Characterizing LAGLIDADG Homing Endonuclease Orthologs Rationale: The LAGLIDADG homing endonuclease I-AniI represents a stable scaffold for enzymological…