Slide 1 PRIONS Defn: small proteinaceous infectious particles that resist inactivation by procedures that modify viruses and nucleic acids Slide 2 Prion / Amyloid Diseases…

Slide 1 Roscoe Brady, M.D. Scientist Emeritus National Institutes of Health Bethesda, Maryland USA Slide 2 CURRENT APPROACHES TO TREAT PATIENTS WITH HEREDITARY METABOLIC…

Slide 1 GRC 2004 Comp Chem Review Russell talks about GRC Computational Chemistry 2004 mol_sims Discussion Group GT Schools of Biology and Chemistry et al July 20, 2004 Slide…

Slide 1 Neurodegenerative Diseases: The Distorted Origami of Protein Misfolding Neil R. Cashman MD Professor and Canada Research Chair Brain Research Centre Department of…

Slide 1 Protein Structure Modeling (1) Slide 2 Protein Folding Problem A protein folds into a unique 3D structure under physiological conditions Lysozyme sequence: KVFGRCELAA…

Slide 1 Rapid detection of drugs for protein misfolding diseases. Alexey Krasnoslobodtsev, Department of Pharmaceutical Sciences, University of Nebraska Medical Center COBRE…

Slide 1 http://parasol.tamu.edu Using Motion Planning to Map Protein Folding Landscapes Nancy M. Amato Parasol Lab,Texas A&M University Slide 2 Soccer Ball 31 dof (10…

Slide 1 Most proteins in the ER are glycosylated Proteins in cytosol are rarely glycosylated original precursor oligosaccharide added to most proteins in the ER Slide 2 Protein…

Slide 1 Lorna Pierce Slide 2 To generate free oligosaccharides characteristic of protein misfolding due to treatment with NB-DNJ To observe the effect of endomannosidase…

Slide 1 Cellular Degeneration and Dementia By Joshua Bower Easter Revision 2014 Questions? [email protected] Slide 2 Degeneration Describe the process of normal cellular…