1. Pedigree Analysis 2. Why do Pedigrees? • Punnett squares and chi-square tests work well for organisms that have large numbers of offspring and controlled matings, but…

Sample pedigree - cystic fibrosis Autosomal recessive traits Trait is rare in pedigree Trait often skips generations (hidden in heterozygous carriers) Trait affects males…

Pedigree Analysis Goals of Pedigree Analysis 1. Determine the mode of inheritance: dominant, recessive, partial dominance, sex-linked, autosomal, mitochondrial, maternal…

Genetics Part II: Probability and Pedigree Nestor T. Hilvano, M.D., M.P.H. (Images Copyright Discover Biology, 5th ed., Singh-Cundy and Cain, Textbook, 2012.) Learning Objectives…

Sample pedigree - cystic fibrosis Autosomal recessive traits Trait is rare in pedigree Trait often skips generations (hidden in heterozygous carriers) Trait affects males…