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1. Ab initio molecular 
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Slide 1 Slide 2 Drug ? Slide 3 RESPONSE altering their biochemical &/or biophysical activity  Depress  Activate  Replace  Irritate  Destroy PHARMACODYNAMICS…

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Slide 1 ©CMBI 2003 MUTANT DESIGN BIO- INFORMATICS QUESTION ‘MOLECULAR BIOLOGY’ BIOPHYSICS Slide 2 ©CMBI 2003 AbstractProtein folding, structure, stability AppliedProcess…

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