1. Pharmacophore-based Ligand Designing usingSubstructure Searching to Explore New Chemical Entities(NCEs) S.Prasanth Kumar, BioinformaticianCopyrightsCopyright © 2011 S.Prasanth…

1. Cholinergics and Anticholinesterases Acetylchlonine (Ach) 2. Our Nervous System Because of its wide and important involvement, understanding Nervous system is important…

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Slide 1 Chapter 14 (part 2) Oxidative phosphorylation Slide 2 Proton Motive Force (  p ) PMF is the energy of the proton concentration gradient The chemical (  pH=…

Slide 1 There are many steps to produce a protein in a eukaryotic cell Each step is a point of regulation to determine the efficiency of gene expression Slide 2 Translation…

Steroids Structure of Cholesterol Fundamental framework of steroids is the tetracyclic unit shown. A B C D Steroids Steroid A/B and B/C Rings Resemble Decalin Methyl groups…

OXIDATIVE PHOSPHORYLATION This complex mechanical art form can be viewed as a metaphor for the molecular apparatus underlying electron transport and ATP synthesis by oxidative…

The Human Perspective ----protein folding can have deadly consequences Creutzfeld-Jakob disease (CJD) Alzheimer’s disease (AD) Creutzfeld-Jakob disease CJD, a rare, fatal…

Short Announcements 5th Homework assigned today; due next Wednesday, Feb 27th Today’s Lecture: Protein Folding, Misfolding, Aggregation tRNA must fit in well to 50S subunit…