Slide 1 1 Lecture outline Sequence alignment –Why do we need to align sequences? –Evolutionary relationships Gaps and scoring matrices Dynamic programming –Global alignment…

Slide 1 Welcome to CS262! Slide 2 Goals of this course Introduction to Computational Biology  Basic biology for computer scientists  Breadth: mention many topics &…

DNA Sequencing link: http://en.wikipedia.org/wiki/DNA_sequencing DNA sequencing From Wikipedia, the free encyclopedia Jump to: navigation, search The term DNA sequencing…

The Ontario Structural Genomics Initiative REFERENCES Nature Structural Biology, 7, 903-909, 2000 Journal of Molecular Biology, 302, 189-203, 2000 Nature Structural Biology,…

DNA Microarray Microarray Printing 96-well-plate (PCR Products) 384-well print-plate Microarray Differential Expression Each cell contains a complete copy of the organism’s…

Slide 1 Sequence Alignment Slide 2 2 Sequence Comparison Much of bioinformatics involves sequences u DNA sequences u RNA sequences u Protein sequences We can think of these…

Advanced Algorithms and Models for Computational Biology Class Overview Eric Xing & Ziv Bar-Joseph Lecture 1, January 18, 2005 Reading: Chap. 1, DTM book Logistics Class…

Advanced Algorithms and Models for Computational Biology -- a machine learning approach Introduction to cell biology, genomics, development, and probability Eric Xing Lecture…