! 1! Dr Jess Healy: PHAY2003 Cardiovascular drugs (Medicinal chemistry) Lecture 1 What makes a good drug? A good drug must have high affinity for its macromolecular target…
Synthetic Lethality Inactivating two interacting pathways causes lethality (or sickness) A B C Product X Y Z X Viable! X Viable! Dead! Synthetic Lethality Synthetic Lethality…