Slide 1 Tolerance & Autoimmunity Slide 2 Two major aspects to regulation of the immune response 1. Developmental pathways of immunocompetence 2. Response of mature lymphocytes…

T – lymphocytes J. Ochotná T lymphocytes cellular component of antigen-specific mechanisms several different subsets of T lymphocytes regulation of immune processes, the…

Autoimmunity All of us have many autoantibodies Difference is in quantiy and consequences Mechanisms how normal immunity change to autoimmunity are multiple Disease from…

8. HOW REPERTOIRES OF ANTIGEN SPECIFIC RECEPTORS ARISE DIFFERENTIATION OF B LYMPHOCYTES BASIC FEATURES OF FORMATION OF THE ANTIGEN-SPECIFIC Ig (BCR): Rearrangement of genes…

MICR 304 Immunology & Serology Lecture 15 Autoimmune Diseases and Transplantation Immunology Chapter 14.1 -14.5, 14.7– 14. 19; 14.22.- 37 Overview of Today’s Lecture…

TOLERANCE Deletion, anergy or ignorance? Normal thyroid Diseased thyroid If the immune system fails to âdeleteâ or anergise tissue reactive lymphocytes, AUTOIMMUNITY occurs…

8. HOW REPERTOIRES OF ANTIGEN SPECIFIC RECEPTORS ARISE DIFFERENTIATION OF B LYMPHOCYTES BASIC FEATURES OF FORMATION OF THE ANTIGEN-SPECIFIC Ig (BCR): Rearrangement of genes…

Nutrition, Environment, and Autoimmunity Sabrina Schmitz EPOB 4800 Spring 2004 OUTLINE REVIEW: IMMUNE SYSTEM “SELF” VS. “NON-SELF” DISTINCTION DEVELOPMENT OF AUTOIMMUNITY…

T – lymphocytes J. Ochotná T lymphocytes cellular component of antigen-specific mechanisms several different subsets of T lymphocytes regulation of immune processes, the…