Slide 1 Transcription and Translation (How a Gene Works) Alison Kraigsley January 18 th, 2011 Slide 2 Overview 1.Brief Introduction 2.My background 3.Research at NIST 4.Today’s…

Slide 1 Are we still evolving? Mapping sites of selection in the human genome Simon Myers Slide 2 Targets of selection are important Humans Other species What makes us human?…

Slide 1 Population genetics, comparative genomics, and natural selection Simon Myers Slide 2 Overview Identifying selection through –Use of comparative genomic data (FOXP2)…

Slide 1 MSA- multiple sequence alignment Aligning many sequences is often preferable to pairwise comparisons. Problem- Computational complexity of multiple alignments grows…

Slide 1 Adaptation, Natural Selection and Evolution Slide 2 What caused all of these? Cystic Fibrosis Haemochromatosis Huntingdon’s Disease Tay-Sachs Syndrome Slide 3 Do…

Slide 1 Rest of Chapter 16 and Chapter 17 Slide 2 Homology Related organisms share DNA sequences inherited from a common ancestor. Slide 3 Homology Over time, the sequences…

Molecular evolution Fredj Tekaia Institut Pasteur [email protected] Institut Pasteur/EMBO/CNPq course, UFSC, Florianopolis, 2008 The increasing available completely sequenced…

Molecular Evolution Sylvia Nagl Relationships between DNA or amino acid sequence 3D structure protein functions Use of this knowledge for prediction of function, molecular…

Molecular evolution Fredj Tekaia Institut Pasteur [email protected] Institut Pasteur/EMBO/CNPq course, UFSC, Florianopolis, 2008 The increasing available completely sequenced…

Cancer â What is it? What is the difference between a benign tumor and a malignant tumor? What is the difference between a sarcoma and a carcinoma? Cancer forms most commonly…