Interventions for Clients with Hematologic Problems WHITE BLOOD CELL DISORDERS White blood cells (WBCs), or leukocytes, provide protection from invading non-self cells and…

Programme 1. Hematological malignancies: acute leukemias, lymphomas 2. Solid tumors, part I: Brain tumors, neuroblastoma, Wilms tumor, hepatoblastoma, germ cell tumors 3.…

Enzyme inhibitors Anthracy clines Daunorubicin Doxorubicin Epirubicin Idraubicin Mitoxantrone Topoismerase inhibitors Etoposide Irinotecarn Topotecan Anthracyclines Inhibit…

Programme 1. Hematological malignancies: acute leukemias, lymphomas 2. Solid tumors, part I: Brain tumors, neuroblastoma, Wilms tumor, hepatoblastoma, germ cell tumors 3.…

HEMATOLOGIC MALIGNANCIES Failure of terminal differentiation Failure of differentiated cells to undergo apoptosis Failure to control growth Neoplastic “stem cell” BIOLOGY…

Mechanisms of leukemia translocations Jac A. Nickoloff, Leyma P. De Haro, Justin Wray, and Robert Hromas Departments of Molecular Genetics and Microbiology and Internal Medicine,…

Antineoplastic Agents Pharmacology II NUR 312 Principles of Chemotherapy The goal is to eliminate all malignant cells without excessive destruction of normal cells Antineoplastic…

Parasitology: (Protozoa and Helminthes) Leukemia Dr. Rania Alhady 1 Maturation of Myeloid Cells Definition: Leukemias are a group of disorders characterized by the accumulation…

HEMATOPOIETIC AND LYMPHORETICULAR SYSTEMS White Blood Cell Disorders Outline ¨  Hematopoiesis ¨  Cell Review ¨  Leukemia ¤  Acute Leukemia ¤ …

Parasitology: (Protozoa and Helminthes) Leukemia Dr. Rania Alhady 1 Maturation of Myeloid Cells * Definition of leukemia: Leukemia is malignant proliferation of hematopoietic…