Enhanced TCR Affinity Imparts Specificity to Reverse Transcriptase Inhibitor Resistance-Associated Mutations. YV9 pentamer. TCR α. TCR β. High affinity YV9 Pol TCRs recognize and respond to drug escape mutations. ( Efavirenz ). IL-2. TNF α. ( Nevirapine ). (Lamivudine). - PowerPoint PPT Presentation
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Washington D.C., USA, 22-27 July 2012www.aids2012.org
Enhanced TCR Affinity Imparts Specificity to Reverse Transcriptase Inhibitor Resistance-