Purines 5. 10 Methylene THF serine glycine Thymidine synthesis dUMP THF B12 Yasko Methylation Pathway © Content and diagrams may not be reproduced without express permission from NRI mercury lead VDR MTHFR DHPR NOS MAO A COMT COMT G6PDH GAD SOD GST OTC ACAT BHMT MAT AHCY CBS SUOX ACE SHMT MTR MTRR Tryptophan Tyrosine Kreb’s Cycle Arginine Ornithine UREA Citrulline + NO taurine 5 Methyl THF Neuronal Damage Microglial Activation Peroxynitrite Super Oxide glutamate gaba Serotonin Dopamine BH4 AMMONIA LEAD BH2 ALUM NorEp SAMe SAH HIAA VMA 0 BH4 1 BH4 2 BH4 SAH HVA Methionine Homocysteine cystathionine Cysteine + , α-ketobutyrate glutathione Guanido AC adenosine SAMe SAH methylation DMG TMG SAH Angiotensin I Angiotensin II cortisol AMMONIA DNA, RNA Protein, lipids “When the need is for energy and not for cysteine, homocysteine is metabolized to Alpha-Ketobutyrate, NH3 and H2S.” Text of Biochemistry with Clinical Correlations, Devlin 2002 Creatine Creatinine glycine α-ketoglutarate NADH/FADH fumarate succinate aspartate oxaloacetate Acetyl CoA citrate isocitrate Pyruvate
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Purines
5. 10Methylene THF
serine
glycine
Thymidinesynthesis
dUMP
THF
B12
Yasko Methylation Pathway© Content and diagrams may not be reproduced without express permission from NRI
mercurylead
VDR
MTHFRDHPRNOS
MAO A
COMT
COMT
G6PDH
GAD
SOD
GST
OTC
ACAT
BHMT
MAT
AHCY
CBS
SUOXACE
SHMT
MTR MTRR
Tryptophan Tyrosine
Kreb’sCycle
Arginine
Ornithine
UREA
Citrulline + NO
taurine
5 MethylTHF
NeuronalDamage
MicroglialActivation
Peroxynitrite
Super Oxide
glutamate gaba
Serotonin Dopamine
BH4
AMMONIA LEADBH2
ALUM
NorEpSAMe
SAHHIAA
VMA
0 B
H4
1 B
H4
2 B
H4
SAH
HVA
Methionine
Homocysteine
cystathionine
Cysteine + , α-ketobutyrate
glutathione
Guanido AC
adenosine
SAMe
SAH
methylationDMG
TMG SAH
Angiotensin I Angiotensin II
cortisol
AMMONIA
DNA, RNAProtein, lipids
“When the need is for energy and not forcysteine, homocysteine is metabolized to
Alpha-Ketobutyrate, NH3 and H2S.”Text of Biochemistry with Clinical Correlations, Devlin 2002
Creatine Creatinine
glycine
α-ketoglutarate
NADH/FADH
fumarate
succinate
aspartateoxaloacetate
Acetyl CoA
citrate
isocitrate
Pyruvate
Related Documents
