www.BioEdOnline.org BioEd Online Overview Mature tissue cell vs a stem cell What is a stem cell? How do we get stem cells? What is the difference between embryonic and adult stem cells? Why are stem cells medically important? Stem cells Photo: NIH Stem Cell Unit
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Www.BioEdOnline.org BioEd Online Overview Mature tissue cell vs a stem cell What is a stem cell? How do we get stem cells? What is the difference between.
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www.BioEdOnline.orgBioEd Online
Overview
Mature tissue cell vs a stem cell
What is a stem cell?
How do we get stem cells?
What is the difference between embryonic and adult stem cells?
Why are stem cells medically important?
Stem cells
Photo: NIH Stem Cell Unit
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Stem cell sphere Cortical neurons
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Stem cell Terminology
Differentiation - cell specialization that occurs at the end of the developmental pathway.
Totipotent - a cell capable of giving rise to any of the cell types in the adult. In humans, the fertilized egg is totipotent until the eight-cell-stage.
Multipotent - can give rise to several other cell types, but those types are limited in number. An example is a blood stem cell that can develop into several types of blood cells, but cannot develop into brain cells.
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• Unlimited Cell Division• Pluripotent
Tissue cells
• Limited Cell Division• Found in tissues• Multipotent
Self-renewal decreases, Differentiation increases
• Blood, Brain etc.• Differentiated
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What is a Stem Cell?
Unspecialized cells
Able to self-renew without differentiating for extended periods of time