World Tuberculosis Day 2014 The TB situation in 2012: Findings from the joint TB surveillance and monitoring report by ECDC and the WHO Regional Office for Europe ECDC TB Team European Centre for Disease Prevention and Control Stockholm, 24 March 2014
World Tuberculosis Day 2014
Feb 25, 2016
World Tuberculosis Day 2014. The TB situation in 2012 : Findings from the joint TB surveillance and monitoring report by ECDC and the WHO Regional Office for Europe . ECDC TB Team European Centre for Disease Prevention and Control Stockholm, 24 March 2014. TB notifications by country. - PowerPoint PPT Presentation
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World Tuberculosis Day 2014The TB situation in 2012: Findings from the joint TB surveillance and monitoring report by ECDC and the WHO Regional Office for Europe
ECDC TB TeamEuropean Centre for Disease Prevention and ControlStockholm, 24 March 2014
TB notifications by countryIn 2012, 68 423 TB cases were reported in the EU/EEA.The notification rate was 13.5 per 100 000 population(range 3.4–85.2).
2
Not included or not reporting
50 to 99 per 100 000
20 to 49 per 100 000
10 to 19 per 100 000
< 10 per 100 000
Figure 1: TB notification rate per 100 000 population by country, EU/EEA, 2012
EU definition: Confirmed TB cases*
3
Figure 2: Percentage of laboratory-confirmed TB cases by country, EU/EEA, 2012
70 to 79%≥ 80%
60 to 69%
< 60%
Not included or not reporting
* Confirmed by culture or by both a positive sputum microscopy result and Mycobacterium tuberculosis nucleic acid identified in nucleic acid amplification test.
Overall, 61.9% (range 21.5–91.4%) of TB cases reported in the EU/EEA were laboratory confirmed.
TB in children
4
Figure 3: TB notification rate in children under 15 years of age per 100 000 child population, by country, EU/EEA, 2012
Not included or not reporting
4 to 9.9 per 100 000 child population
2 to 3.9 per 100 000 child population
≥ 10 per 100 000 child population
< 2 per 100 000 child population
In 2012, 2 845 TB cases in children were reported, accounting for 4.2% of all notified TB cases (range 0–7.8%) in the EU/EEA.
TB cases of foreign origin
5
In 2012, the overall proportion of TB cases of foreign origin in the EU/EEA was 26.8% (range 0.2–85.4%).Figure 4: Percentage of TB cases of foreign origin by country, EU/EEA, 2012
25 to 49.9%
≥ 75%
1 to 24.9%
50 to 74.9%
< 1%
Not included or not reporting
Extrapulmonary TB cases
6
In 2012, the overall proportion of extrapulmonary TB cases in the EU/EEA was 23.0% (range 2.9–48.6%).Figure 5: Percentage of extrapulmonary TB cases by country, EU/EEA, 2012
20 to 29.9%
≥ 40%
10 to 19.9%
30 to 39.9%
< 10%
Not included or not reporting
Extrapulmonary TB notification over timeExtrapulmonary TB notification rates have remained stable in the last 10 years.
7
Figure 6: Extrapulmonary TB notification rate per 100 000 population by year, EU/EEA, 2003−2012
2003 2004 2005 2006 2007 2008 2009 2010 2011 20120
1
2
3
4
Year of reporting
Notifi
catio
n ra
te p
er 1
00 0
00 p
opul
atio
n
Multidrug-resistant TB
8
In 2012, the overall proportion of TB cases with multi-drug resistance in the EU/EEA was 4.6% (range 0–25.5%).Figure 7: Percentage of multidrug resistance among all confirmed TB cases by country, EU/EEA, 2012
2 to 4.9%
≥ 10%
1 to 1.9%
5 to 9.9%
< 1%
Not included or not reporting
Multidrug-resistance among new pulmonary TB cases
9
Figure 8: Percentage of new pulmonary TB cases with multidrug resistance by country, EU/EEA, 2012
2 to 4.9%
1 to 1.9%
≥ 5%
< 1%
Not included or not reporting
In 2012, the overall percentage of new pulmonary TB cases with multidrug resistance in the EU/EEA was 2.6% (range 0–20.5%).
Multidrug-resistance among previously treated pulmonary TB cases
10
In 2012, the overall proportion of previously treated pulmonary TB cases with multidrug resistance in the EU/EEA was 18.8% (range 0–50.0%).
Figure 9: Percentage of previously treated pulmonary TB cases with multidrug resistance by country, EU/EEA, 2012
10 to 19.9%
≥ 20%
1 to 9.9%
< 1%
Not included or not reporting
Extensively drug-resistant TB
11
In 2012, the proportion of extensively drug-resistant TB cases among multidrug-resistant cases in EU/EEA was 13.7% (range 0–50.0%).
Figure 10: Percentage of extensively drug-resistant TB cases among multidrug-resistant TB cases tested for second-line drug susceptibility, by country, EU/EEA, 2012
10 to 19.9%
1 to 9.9%
≥20%
< 1%
Not included or not reporting
TB/HIV co-infection
12
In 2012, the overall proportion HIV positive among TB cases with known HIV status in EU/EEA was 5.5% (range 0–16.5%).
Figure 11: Percentage of HIV-positive cases among TB cases with known HIV status, by country, EU/EEA, 2012
5 to 9.9%
2 to 4.9%
≥ 10%
< 1%
Not included or not reporting
Treatment success in new pulmonary TB cases over timeThe treatment success rate in new culture-confirmed pulmonary TB cases notified between 2007 and 2011 has slightly decreased from 79.2% in 2007 to 76.5% in 2011.
13
Figure 12: 12-month treatment success rate in new culture-confirmed pulmonary TB cases by year of initial case reporting, EU/EEA, 2007–2011
2007 2008 2009 2010 20110
20
40
60
80
100
79.2 79.4 79.0 77.0 76.5
Year of initial reporting
Trea
tmen
t suc
cess
(%)
Treatment success in new pulmonary TB casesTreatment success rate for culture-confirmed new pulmonary TB cases notified in 2011 was 76.5% (range: 0–91.3%).
14
Figure 13: Treatment success rate in culture-confirmed new pulmonary TB cases notified in 2011, by country, EU/EEA, 2012
* Iceland and Malta reported zero new TB cases in 2011. Three EU/EEA Member States did not report treatment outcome data
EU/EE
AAustr
ia
Belgium
Bulgaria
Cyprus
Czech Rep
ublic
Denmark
Eston
ia
Finlan
d
German
y
HungaryIre
landLat
via
Lithuan
iaMalt
a
Netherl
ands
NorwayPo
land
Portu
gal
Roman
ia
Slovak
ia
Sloven
iaSpain
Sweden
United Kingdom
0
20
40
60
80
100
Trea
tmen
t suc
cess
(%)
Treatment success in previously treated pulmonary TB casesThe treatment success rate for previously treated culture-confirmed pulmonary TB cases notified in 2011 was 55.2% (range 25.0–100.0%).
15
Figure 14: Treatment success rate in previously treated culture-confirmed pulmonary TB cases notified in 2011, by country, EU/EEA
* Iceland and Malta reported zero previously treated TB cases in 2011. Three EU/EEA Member States did not report treatment outcome data stratified by treatment history
Subtot
al EU
/EEAAu
stria
Belgi
um
Bulga
riaCy
prus
Czech
Republi
c
Denmark
Eston
iaFin
land
German
y
Hunga
ryIre
land
Latvia
Lithuan
ia
Netherl
ands
Norway
Polan
d
Portug
al
Romani
a
Slova
kia
Slove
nia Spain
Swede
n
United
Kingdo
m0
20
40
60
80
100%
Trea
tmen
t suc
cess
(%)
Treatment success rate in confirmed pulmonary TB cases*The treatment success rate for all confirmed pulmonary TB cases notified in 2011 was 72.4% (range 0–90.4%).
16
Figure 15: Treatment success rate in laboratory confirmed pulmonary TB cases notified in 2011, by country, EU/EEA, 2012
* Four EU/EEA Member States did not report treatment outcome data
EU/EE
AAustr
ia
Belgium
BulgariaCyp
rus
Czech Rep
ublic
Denmark
Eston
ia
Finlan
d
German
y
HungaryIre
landLat
via
Lithuan
ia
Luxe
mbourg
Malta
Netherl
ands
NorwayPo
land
Portu
gal
Roman
ia
Slovak
ia
Sloven
iaSpain
Sweden
United Kin...
0
20
40
60
80
100
Trea
tmen
t suc
cess
(%)
Treatment success rate in extrapulmonary TB*The treatment success rate in extrapulmonary TB cases notified in 2011 was 82.2% (range 59.0–100%).
17
Figure 16: Treatment success rate in extrapulmonary TB cases notified in 2011, by country, EU/EEA, 2012
* Five Member States did not report stratified treatment outcome data
EU/EE
AAustr
ia
Belgium
BulgariaCyp
rus
Czech Rep
ublic
Denmark
Eston
ia
German
y
Hungary
Icelan
dIre
landLat
via
Lithuan
iaMalt
a
Netherl
ands
Norway
Polan
d
Portu
gal
Roman
ia
Slovak
ia
Sloven
iaSpain
Sweden
United Kin...
0
20
40
60
80
100
Trea
tmen
t suc
cess
(%)
Treatment success rate in multidrug-resistant TB*The treatment success rate for all multidrug-resistant TB cases notified in 2010 was 33.6% (range 0–100.0%).
18
Figure 17: 24-month treatment success rate in multidrug-resistant TB cases notified in 2010, by country, EU/EEA, 2012
* Slovenia reported zero MDR TB cases in 2010, 9 Member States did not report treatment outcome data for MDR TB cases
EU/EE
AAust
ria
Belgium
Bulgari
a
Czech R
epub
lic
Denmark
Eston
ia
German
y
Hunga
ryIre
land
Latvi
a
Lithu
ania
Malta
Netherl
ands
Norway
Polan
d
Portu
gal
Roman
ia
Slova
kia
Swed
en
United
King
dom
0
20
40
60
80
100
Trea
tmen
t suc
cess
(%
)
Treatment outcome in multidrug-resistant TB over timeTreatment outcomes for multidrug-resistant TB cases improved slightly between the 2008 and 2010 cohort, EU/EEA.
19
Figure 18: 24-month treatment outcome in multidrug-resistant TB cases notified from 2008 to 2010, by year of initial case reporting, EU/EEA, 2012
Success Died Failed Defaulted Still on treatment
Transferred or unknown
0
10
20
30
40
cohort 2008cohort 2009 cohort 2010
Trea
tmen
t suc
cess
(%
)
20
Treatment success in extensively drug-resistant TB*The treatment success rate in extensively drug-resistant TB cases notified in 2009 was 25.0% (range 0–66.7%).
20
Figure 19: 36-month treatment success rate in extensively drug-resistant TB cases notified in 2009, by country, EU/EEA, 2012
* Cyprus, Denmark, Iceland, Malta, Slovakia, Slovenia and Sweden reported zero XDR TB cases in 2009, 12 countries did not report SLD DST results or stratified treatment outcome data
EU/EEA Austria Belgium Bulgaria Czech Republic
Estonia Latvia Lithuania Norway Poland Romania United Kingdom
0
20
40
60
80
Trea
tmen
t suc
cess
(%
)
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