Working together to improve patient health

Working together to improve patient health

At the Heart of Haemostasis

A benchmark in Haemostasis*

Stago is an international, independent and privately-owned group established in 1945 in France that operates in the In Vitro Diagnostics industry, and that is recognised worldwide for its expertise in the exploration of Haemostasis and Thrombosis.

• Plasma Haemostasis: blood coagulation tests

• Cellular Haemostasis: platelets, microparticles

• Thrombin generation and global tests: dynamic approach to Haemostasis

Stago provides global and upgradable solutions that meet the needs of clinical pathology laboratories and healthcare services, including complete systems (analysers, reagents, disposables, middleware) and a wide range of services.

A FULL COMMITMENT TO HUMAN HEALTHStago’s corporate mission is to provide pathologists and clinicians with safe and efficient diagnostic solutions, to better understand, treat and monitor conditions involving blood coagulation disorders and hence improve patient management.

Subsidiaries

Distributors

1945

Creation of the Stago Laboratory (Pharma)

1962

Development of the first

Haemostasis reagents

1976

The company focuses its

activity solely on In Vitro

Diagnostics

1985

1st subsidiary in the

United States

1987

Development of the 1st

Haemostasis analyser

1994

BioCytex joins the

Stago Group

2000

New reagent production unit

(Taverny, France)

2003

Subsidiary in China

2005

Subsidiary in the UK

2008

Subsidiaries in Australia/

New Zealand, Canada and Dubai

(UAE)

2009

Creation of DSRV Inc.

Acquisition of Synapse and

Thrombinoscope

2010

Creation of Tcoag

(acquisition of Trinity Biotech’s coagulation BU)

2011

Subsidiary in Hong Kong

2012

8 subsidiaries in Europe:Germany, Austria,

Belgium, Spain, Italy, Netherlands, Portugal,

Switzerland

2014

Subsidiary in India

2016

Subsidiaries in Brazil and

Turkey

2017

Acquisition of HemoSonics

(Point of Care)

* Haemostasis covers all the mechanisms involved in maintaining the fluidity and integrity of blood circulation, which when disturbed can cause various disorders, from haemorrhaging to thrombosis.

Thrombosis is a serious condition responsible for

1 in 4 deaths

worldwide.

A FULL COMMITMENT TO HUMAN HEALTH

GENERATE WELL-BEING

Full controlStago integrates and controls the entire value chain, from design and manufacture to product distribution and maintenance.To support its growth, Stago has always acted as a business developer, leveraging strategic intelligence, its investment capacity and opportunities to build partnerships and make targeted acquisitions.

A global presenceStago markets its product brands in over 110 countries with: • A constantly expanding network of subsidiaries • A network of regularly evaluated distributors • R&D, Production and Logistics units: in France, the United States, Germany,

Ireland, China and the Netherlands.

We believe that quality and sustainable development help foster development and progress

- ISO 13485, ISO 9001 certification, (all sites)

- ISO 14001 certification (Reagent Production Unit, Taverny, France)

Antibody engineering

Cellular Haemostasis

Specialised tests

Near-patient testing (POC)

Thrombin generation

Industrial & commercial synergies

Founding action

Creation of a subsidiary(ies)

Acquisition/integration

1945

Creation of the Stago Laboratory (Pharma)

1962

Development of the first

Haemostasis reagents

1976

The company focuses its

activity solely on In Vitro

Diagnostics

1985

1st subsidiary in the

United States

1987

Development of the 1st

Haemostasis analyser

1994

BioCytex joins the

Stago Group

2000

New reagent production unit

(Taverny, France)

2003

Subsidiary in China

2005

Subsidiary in the UK

2008

Subsidiaries in Australia/

New Zealand, Canada and Dubai

(UAE)

2009

Creation of DSRV Inc.

Acquisition of Synapse and

Thrombinoscope

2010

Creation of Tcoag

(acquisition of Trinity Biotech’s coagulation BU)

2011

Subsidiary in Hong Kong

2012

8 subsidiaries in Europe:Germany, Austria,

Belgium, Spain, Italy, Netherlands, Portugal,

Switzerland

2014

Subsidiary in India

2016

Subsidiaries in Brazil and

Turkey

2017

Acquisition of HemoSonics

(Point of Care)

70 % of medical

decisions are based on

laboratory tests

A SYNTHESIS OF SOLID EXPERTISERecognised by the international scientific community for its contribution to progress in Haemostasis, Stago has extensive expertise and allocates substantial resources to R&D, Production and Logistics.

Combining expertiseStago designs complete solutions meeting the needs of pathologists and clinicians with the aim of improving patient care.In permanent contact with the scientific community, Stago is continuously searching for new clinically-relevant markers and exploration tests. These partnerships bring innovative, automated and standardised tests to the market.

Clinical Pathology Chemistry Thermal

Science Fluidics Optics Mechanics

Electronics Software Middleware Artificial Intelligence (AI) Robotics Ergonomics

Engineering

R&D partnerships

Instrumentation & reagent development

Scientific & medical partnerships (public/private)

University research

Pharmaceutical research

Prospective & clinical research

Multidisciplinary teams

Continuously innovatingStago has nearly 20% of its employees working in Research & Development and makes significant and regular investments, giving itself the means to develop innovative technologies that find concrete expression in patents.

A SYNTHESIS OF SOLID EXPERTISE

Producing and distributingCommitted to the Lean Six Sigma approach through “training/action” programmes, its Production and Logistics teams are part of a continuous improvement process aimed at ensuring the highest levels of product quality while optimising production and delivery times.

To more effectively market its product lines throughout the world, Stago has developed strong expertise in process flow and inventory management:

• Establishment of logistics platforms• Control of freight (road, air, sea)• Traceability of storage and delivery conditions• Knowledge of customs regulations

GENERATE KNOWLEDGE

Selectthe best suppliers

Master production

Integrate quality control at all stages

Optimise workstation ergonomics

Reduce cycle times

Secure customer

supply

The multiplication of expertise, skills and experience leads to innovation, and conditions its success, as well as the ability to control its development.

EFFICIENT, GLOBAL SOLUTIONSIn the field of health, absolute reliability of blood tests means a higher quality of care. Stago therefore places a priority on designing user-friendly, robust, efficient and standardised systems.

Adapting to all clinical pathology needsClinical pathology practices and regulations vary from country to country. Stago is able to propose appropriate solutions whatever its customers’ practices,

location, specific requirements or status.

Complete and consistent system rangesThe analysers designed by the Stago Group are easy to use and equipped with functionalities and technologies that guarantee standardisation, traceability and comparable results. • They cover the needs of all clinical pathology laboratories,

irrespective of their activities.

• They meet the requirements of near-patient testing in

emergency situations (Point of Care, Critical Care).

• They are equipped with innovative and benchmark measurement systems,

including the Viscosity-based Detection System VBDS , Dual Technology

and Sonorheometry .

Max Generation

Tcoag systems Thrombin generation

?

53 627Number of Stago analysers installed worldwide since the start of instrumentation*.

* as of 1 Jan 2018

STart STA STA STA STA R Max integrated Max Satellite Max Compact Max R Max into a lab automation track

CAT ST Genesia

Platelet aggregation

TA-8V / TA-4V

VBDS

DT

SEER

DT 100KC1Delta

KC4Delta

Point of Care

SEER

Quantra

DT

Analyser availability depending on the country

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EFFICIENT, GLOBAL SOLUTIONS

A unique panel of testsWith more than 400 reagents currently on the market, including routine and

specialised parameters and research kits, Stago is recognised as a world reference

in Haemostasis. Its wide range of tests offers choice of:

• technology (chronometry • colorimetry • cytometry • immunology)

• origin (animal • recombinant)

• packaging (volume • number of tests)

Accompanied by a full range of Quality Control services:

• Internal Quality Control ( IQC), My Daily QC

• Externalised IQC platform, My Expert QC (web platform of comparison groups)

• External Quality Assessment (EQA), My Qualiris QC (program offering different options via a secure website)

From primary Haemostasis to fibrinolysis, from thrombophilia assessments to

thrombin generation, from platelet studies to anticoagulant treatments, Stago

provides specialists and researchers with all the tools, proteins and substrates

necessary for full Haemostasis exploration.

The value of a product is defined by the recognition of its users. It must meet their productivity, quality and standardisation requirements to increase laboratory performance.

- ISO 17043 accreditation

GENERATE PERFORMANCE

Routine tests

Specialised tests

Research tests

CUSTOMER SATISFACTION, OUR PERMANENT OBJECTIVE

It takes more than increasingly innovative, robust and user-friendly products to guarantee complete laboratory efficiency. This is why Stago offers a broad range of services to support its products and further optimise their performance.

Analysing and understanding needs Stago has teams of rigorously selected and trained staff able to provide services the world over, by drawing on their global knowledge of Haemostasis and laboratory practices.Their strength lies in their complementary expertise, and in their ability to listen, understand, react swiftly and give advice.

Optimisation of the “Haemostasis”

workstation

Audit & flow analysis (Lean Six Sigma method)

Connection to IT systems

Remote control for predictive maintenance

Integration of Stago systems into

lab automation tracks

Assistance with accreditation

Follow-up of clinical and

scientific studies

Ethics, a core Stago valueThe Stago Group fosters multiculturalism, team spirit and professionalism, to promote a human-scale and eco-responsible corporate culture. For each employee, ethics is a state of mind, present in the day-to-day development of tests, during clinical studies and more generally when working with partners. For Stago, as a company involved in human health, ethics comes as second nature. Placing the patient at the forefront of our minds has always been a fundamental, long-term commitment.

Stago GroupCode of Ethics

CUSTOMER SATISFACTION, OUR PERMANENT OBJECTIVE

Assisting performanceVarious initiatives are proposed to pathologists and to their technical teams to help them improve their scientific, theoretical and practical knowledge of Haemostasis:

Appropriate solutions for everyday situationsLaboratories are tasked with providing clinicians with validated test results as rapidly as possible. Stago support teams must therefore ensure nothing disrupts their flow of activity. More than 90% of calls are resolved on the phone, demonstrating the importance Stago attaches to the quality of its hotline service in all its subsidiaries and distribution offices.

Customer satisfaction is a core value in the Group, and a daily commitment for its 2,500 employees. We make every effort to contribute to the pursuit of excellence in every laboratory.

Training Symposia, Master classes

User meetings

Webinars Digital applications

Scientific publications

We firmly believe that our company’s sustainability depends on our ability to establish a lasting and mutually beneficial relationship with every customer.

GENERATE SATISFACTION

Health facilities

Pharmaceutical laboratories

Clinical pathology

laboratories

Medical & clinical research

OUR PARTNERS

SUBSIDIARIES

GermanyStago Deutschland GmbH Cecilienallee 6-7D-40474 - Düsseldorf - Germany Tel.: +49 211/913237-00 Fax: +49 211/913237-11 [email protected]

AustraliaDiagnostica Stago Australia Pty.Ltd. Ground Floor, 351 Burwood Highway - Burwood East. VIC 3151 - AustraliaTel.: +61 3 9840 5555Fax: +61 3 9855 [email protected] www.stago.com.au

AustriaStago Österreich GmbHWienerbergstraße 111100 Vienna - AustriaTel.: +43 (0)1 2530303 0Fax: +43 (0)1 2530303 [email protected]

BelgiumStago BNL B.V.Wallonia 9, rue Émile Francqui1435 Mont-Saint-Guibert - [email protected]

Flanders Kanaalpark 140NL-2321 JV Leidenthe NetherlandsTel.: +31 71 890 0460Fax: +31 71 522 [email protected]

BrazilStago BrasilAv. Eng. Luis Carlo Berrini, 105Ed. Berrini One - 28e andarSao Paulo, SP - 04571-010 BrasilTel. : +55 11 [email protected]

CanadaStago Canada Ltd./Ltée.6790 Century Avenue, Suite #102Mississauga, ON L5N 2V8 - Canada Tel. : +1 888 283 [email protected]@ca.stago.comwww.stago-ca.com

China Stago Diagnosis Trading Co., Ltd. Citychamp Building, Floor 11, No.12 Taiyanggong Middle Road Chaoyang District 100028 Beijing - ChinaTel.: +86 10 8444 1888Fax: +86 10 8444 [email protected]

SpainDiagnostica Stago S.L.U.Plaza Europa 9-11, planta 2308908 L’Hospitalet de Llobregat Barcelona - SpainTel.: +34 93 116 51 38Fax: +34 93 259 13 [email protected]

United StatesDiagnostica Stago Inc. Five Century Drive Parsippany, NJ 07054 - USA Tel.: +1 973 631 1200Fax: +1 973 631 [email protected] www.stago-us.com

France (head office)Diagnostica Stago S.A.S.3 allée Thérésa92600 Asnières sur Seine - FranceTel.: +33 1 46 88 20 20 Fax: +33 1 47 91 08 91 [email protected] [email protected] / www.stago.fr

IndiaStago India Private Ltd. Office 605, Welldone Tech Park Sector-48, Sohna Road Gurgaon -122002 - IndiaTel.: +91 124 4114126Fax: +91 124 [email protected]

ItalyStago Italia S.r.l. - Unipersonale Via Giovanni Antonio Amadeo, 5920134 Milan - Italy Tel.: +39 02 49588 501 Fax: +39 02 49588 550 [email protected] / www.stago.it

New ZealandDiagnostica Stago Pty.Ltd. New Zealand Branch64 Cashel StreetChristchurch, 9013 - New ZealandContacts : voir Australie

NetherlandsStago BNL B.V.Kanaalpark 140 NL-2321 JV Leidenthe NetherlandsTel.: +31 71 890 0460 Fax: +31 71 522 1700 [email protected] www.stago-bnl.com

PortugalStago Portugal, Unipessoal, Lda. Alfrapark - Estrada de Alfragide, n° 67Edificio F - Piso 0 - Norte2610-008 Amadora - PortugalTel.: +351 21 193 52 00Fax: +351 21 193 56 [email protected]

STAGO, AT THE HEART OF DIGITAL HEALTHDigital technologies are being used increasingly in the world of health, fundamentally transforming patient follow-up and care while encouraging their own involvement.

As a company operating at the heart of In Vitro Diagnostics, Stago is fully committed to this technological transformation. Its research teams are designing products and developing support and information tools for healthcare players using artificial intelligence (AI) and big data technologies. In this context, cybersecurity has become an essential requirement, from the design phase through to system implementation in laboratories.The digital transformation has implications at all levels of the Group.

Digital health is defined as the use of information and communication technologies (ICT) in all health-related activities. There is also what is known as e-health, which includes telehealth, telemedicine, connected health and digital health.

STAGO WORLDWIDE

STAGO, AT THE HEART OF DIGITAL HEALTH

United KingdomDiagnostica Stago UK Ltd. 2 Theale Lakes Business ParkMoulden WayTheale RG7 4GB - EnglandTel.: +44 845 054 0614 Fax: +44 845 054 0625 [email protected]

SwitzerlandStago CH S.A.Sägereistrasse 208152 Glattbrugg - SwitzerlandTel.: +41 43 497 27 55Fax: +41 43 497 27 57 [email protected]

TurkeyAlbioInonu Mahallesi,Kayisdagi Caddesi Kurtoglu Sokak, Arslan Is Merkezi N°13Kadikoy 34752 - Istanbul - TurkeyTel. : +90 216 - 576 2000Fax : +90 216 - 576 [email protected]

DISTRIBUTIONOFFICES

Latin AmericaStagoAv. Eng. Luis Carlo Berrini, 105Ed. Berrini One - 28e andarSao Paulo, SP - 04571-010 BrasilTel. : +55 11 [email protected]

South East Asia Diagnostica Stago Hong Kong Ltd. Suite 1009, 10/F, Cityplaza OneTaikoo Shing Island EastHong KongTel : +852 2711 1400Fax : +852 2711 [email protected]

Middle EastStago (Branch)Dubai Airport Free ZoneP.O. Box 293859Dubai - the United Arab Emirates Tel.: +971 4 609 15 46 Fax: +971 4 609 15 50 [email protected]

R&D / PRODUCTIONLOGISTICS

Diagnostica Stago2, Rue Pierre Fossati95130 Franconville - France

125, avenue Louis RocheP.A.E. Parispace 392230 Gennevilliers - France

14-16, Avenue des BéthunesZ.I. Parc d’Activités des Béthunes95310 Saint-Ouen-l’Aumône - France

23-29 rue Constantin Pecqueur Z.A.C. Les Châtaigniers95150 Taverny - France

Diagnostica Stago Inc. Distribution330 Waterloo Valley RoadMount Olive, NJ 07828 - U.S.A

Stago Diagnosis Technology Co., Ltd. No. 208, Jing Si Road, Tianjin Airport Economic Area, 300308 Tianjin, China

TcoagTcoag Ireland Ltd. IDA Business ParkSouthern Cross RoadBray, Co. Wicklow - Irelandwww.tcoag.comTcoag Deutschland GmbHLehbrinksweg 5932657 Lemgo - Germany

Agro-Bio2, allée de la Chavannerie45240 La Ferté Saint-Aubin Francewww.agro-bio.com

BioCytex140, chemin de l’Armée d’Afrique13010 Marseille - Francewww.biocytex.com

DSRV Inc. 330 Waterloo Valley RoadMount Olive, NJ 07828 - U.S.A

HemoSonics LLC 400 Preston Ave, Suite 250 Charlottesville, VA 22903 - USAwww.hemosonics.com

Synapse B.V.University MaastrichtOxfordlaan 706229 EV Maastricht the Netherlands www.thrombin.nl

Thrombinoscope B.V.Oude Maasstraat 476229 BC Maastricht the Netherlands www.thrombinoscope.com

STAGO WORLDWIDE

Stago is distributed in over 110 countries.Find out more at: www.stago.com/worldwide

Embedded connectivity and digital technologies

Clinical decision support tools (CDS/AI)

Paperless documents & processes

E-learning modules

Webinars on demand

Networks

Serious games

Digital applications

Cybersecurity

Diagnostica Stago S.A.SRCS Nanterre B305 151 4093 allée Thérésa92600 Asnières sur Seine FrancePh. +33 (0)1 46 88 20 20Fax +33 (0)1 47 91 08 [email protected]

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iHemostasisAVAILABLE ON THE

App Store

T a b l e t o n l y

HaemoscoreAVAILABLE ON THE

App Store

Tablet & smartphone

Webinars

Available on Stagowebinars.com

Stago

@StagoEvents

Stago

LinkedIn Twitter YouTube

a r e c o m p a n i e s o f t h e S t a g o G r o u p

HEMOSONICS DSRV inc

For more information, please contact:

Haemostasis

General information on Stago.com

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