Adaptogen* Immunomodulator Rejuvenative* * What is Withania somnifera? Adaptogen An ideal “Adaptogen” ● ● ● Biological actions of ashwagandha Withania somnifera Dunal (solanaceae) is a popular Indian plant commonly known as or Indian Ginseng. is widely used in Ayurveda and has long been known for its health benefits. Adaptogens are a class of pharmacologically active substances that, in a nonspecific manner, enhance the resistance of an organism to adapt to various stressors. Must show a nonspecific activity, for example an increase in resistance power against physical, chemical or biological noxious agents. Must have a normalizing influence independent of the nature of pathological state. Must be innocuous and must not influence normal body functions than required. has been experimentally proven to be a good adaptogen in a variety of stress related models. These include forced swimming test, stress induced gastric ulcer, anabolic activity, learning acquisition etc. Corticosteroid sparing effect has been proposed as one of the mechanisms for its adaptogenic activity. In addition several studies have confirmed its antioxidant and immunomodulatory properties. ashwagandha Ashwagandha Ashwagandha Ashwagandha ashwagandha ashwagandha ashwagandha is recommended to be a good ingredient for the nutritional/ health supplements useful as adaptogen and immunomodulator. “ ” are rejuvenators, believed to promote health, immunity, and longevity. According to Ayurveda, they strengthen all the tissues of the body, prevents aging, promotes intellect and prevent diseases. The available human studies on do not indicate any significant adverse effects. Both acute and chronic administration of did not have any toxic effects in animal studies. In addition, a strong traditional support from Ayurveda is available to substantiate the safety of . Withania somnifera Dunal is official in Ayurvedic Pharmacopoeia of India and Indian Pharmacopoeia. It is listed in American Herbal Pharmacopoeia and Therapeutic Compendium, Indian Herbal Pharmacopoeia, Pharmacopoeial Standards for Ayurvedic Formulations, Australian Register of Therapeutic Goods and Herbs of commerce- American Herbal Products Association. HPLC based quality control : Ensures consistent chemical profile with known amounts of both free withanolides and their glycosides in the extract. Supported with phytochemical reference standards (with spectroscopic and chromatographic characterization). Manufactured in a GMP and ISO 9001 - 2000 certified manufacturing facility. The product is Kosher and Halal certified. Withania somnifera Dunal extract standardized to free withanolides and their glycosides (total withanolides > 5% w/w by HPLC). Standardized extract of Withania somnifera can be custom formulated. Between 600 and 1200mg / adult / day. RASAYANA Safety : Regulatory Status : Why Withania somnifera extract from ? ● ● ● ● Availability : Recommended Dose : Natural Remedies *Disclaimer : “These statements have not been evaluated by the Food and Drug Administration or any other regulatory body. This product is not intended to diagnose, treat, cure or prevent any disease”. Standardized Extract Plot No. 5B, Veerasandra Ind. Area, 19th Km Stone, Hosur Rd, Electronic City Po., Bangalore - 560 100. INDIA Ph : +91 80 4020 9999 / 98 / 97 / 96 Fax : +91 80 4020 9817 E-mail : [email protected] , Web: www.naturalremedy.com Withania somnifera Ashwagandha Ver.1201 Manufactured by