Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubin- emia. Hyperbilirubinemia is a condition which excessive serum bilirubin in the blood. It affects both full-term and premature babies, usually appearing during the first week of the baby's life. • Physiologic jaundice • Breast milk jaundice • Breastfeeding failure jaundice • Jaundice from hemolysis • Jaundice related to inadequate liver function It can be considered one of the most frequent healthcare problems in preterm infants. The incidence of visible jaundice is around 80% in preterm infants and 50-60% of all newborns are jaundiced in the first week of life. Bilirubin is potentially toxic to the central nervous system. Untreated or uncon- trolled jaundice can lead to permanent neurological damage (kernicterus) and sei- zures. Definitive treatment of hyperbilirubinemia includes phototherapy and blood trans- fusion. What is Jaundice? What causes jaundice? How frequent Janudice occurs in neonates? Why jaundice need be treated or controlled? How to treat jaundice? www.inspired-medical.com