Wellness Presentation

The Birth of Pharmanex• Director Medicinal

Chemistries, MERCK

• Identified need for quality control and standards in unregulated nutritional industry

• Achieved $50 million/yr in sales

• Purchased by Pharmanex in 1998 for $135 million

Over 125 PHD level ScientistsDisciplines including

• Botanists• Pharmacognosist• Natural Product Specialists• Medicinal, analytical and process

chemists

• Quality control specialists• Biochemists• Molecular biologist• Pharmacologists• Toxicologists

Pharmanex Scientific Advisory Board

Brilliant Minds Endorse...Brilliant Minds Endorse...• Lester Packer – Antioxidant Miracle. Father of

antioxidants. “This validates my life’s work.”

• James Rippe, MD - Tufts, Boston (Cardiologist)

• James Balch, MD – author The Prescription for Nutritional Healing - 8 million copies sold

• Koji Nakanishi – Columbia, Father of Ginkgo Biloba research

• Carl Dierassi – Stanford, birth control pill.

• Chi - Huey Wong – Scripps Institute, appointed to the National Academy of Sciences

Selection

To locate the botanicals with the most effective health-promoting properties, Pharmanex employs teams of experts from the United States and Asia. These teams conduct exhaustive research-compiling, reviewing, and summarizing historical use and current intelligence about a botanical's properties and health benefits. Pharmanex also conducts original research to identify new botanicals, coordinating with noted professionals at Purdue University, Kansas University, Columbia University, Scripps Research Institute, and Beijing University, among others. Only botanicals that pass extensive Pharmanex tests for authenticity, usefulness, and safety are considered.

Sourcing

Once Pharmanex decides to proceed with a particular botanical, a team investigates potential sources of the botanical and conducts exhaustive analyses on samples from each source. Sources may be domestic or international and may include Pharmanex cultivation areas in China and Chile. Pharmanex chooses a supplier based on the quality and concentration level of the active ingredient(s) present in samples from that source.

Structure

Using state-of-the-art analytical techniques and working in collaboration with respected universities and laboratories in both China and the United States, Pharmanex conducts structural analyses of the natural compounds present in the selected botanical. These analyses isolate and purify specific chemical structures in standardized extracts, a critical step in ensuring a safe and effective botanical.

Standardization

Wide variations in active ingredients are characteristic of any botanical. For example, when Pharmanex analyzes potential Ginkgo biloba leaves, studies reveal the concentrations of active components will vary by as much as 300% depending on season, climate, soil, method of harvest, storage conditions, and processing. Pharmanex optimizes the active ingredients of a product through strict, proprietary standardization processes (to at least one relevant marker molecule). Each capsule of a Pharmanex product contains the same amount of each active ingredient.

Safety

Pharmanex is leading the way in establishing strict standards to ensure the safety of its products. Scientists research and document the history of a product's use and safety. Pharmaceutical-grade tests for the presence of microbes, toxins, and heavy metals are carried out for all products. The active ingredient amount used is based on dosages found effective through clinical trials and is backed by published data on file at Pharmanex. Each product label details directions for use and contains appropriate warning information.

Substantiation

Pharmanex only makes product claims that have been substantiated through documented preclinical and clinical studies. Existing clinical data are reviewed, and when necessary, Pharmanex sponsors studies of its products. Data from some of these studies are subsequently submitted to major international journals for review. This adherence to scientific standards for substantiation helps make Pharmanex a leader in the natural healthcare product industry.

First Supplement with all 3 Certifications!

• NSF (www.nsf.org)– Exhaustive formulation & toxicology analysis– FDA, cGMP, NSF, ANSI compliance

• BSCG (www.bscgi.org)– Free from 80+ banned substances by IOC,

WADA, USADA, NFL, NCAA

• ConsumerLab.com (www.consumerlab.com)– Ingredient verification– Only MVMS to test and pass in 6 categories

Substantiation

As of 2004,

nine of the Pharmanex Products are now listed in the

Physician’s Desk Reference (PDR)

THE NEXT BIG THING

"The amount of ANTIOXIDANTS that you maintain in your body is directly

proportional to how long you will live.“

Dr. Richard Cutler, Director of the Anti-Aging Research Department of the National

Institute of Health(NIH), Wash D.C.

The fastest growing market is in

Health and Wellness which was $300 billion last year

and is projected to rise to

$1 trillion by the year 2010.

Baby boomers are 25% of the population and

represent 50% of the spending.

Fact

The Problem

Free Radicals are unstable molecules that

cause cell and DNA damage;

They are a by-product of metabolism.

Indisputable

30,000 Published Papers

Document the link

between

Free Radical Activity

and Disease

Eye HealthNIH Studies - .Age-Related Eye Disease Study Research Group (AREDS). A Randomized, Placebo-Controlled, Clinical

Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss. Arch Ophthalmol 2001;119:1417-1436.

Age-Related Eye Disease Study Research Group (AREDS). A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E and Beta Carotene for Age-Related Cataract and Vision Loss. Arch Ophthalmol. 2001;119:1439-1452.

Packer L. Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts. Ann N Y Acad Sci 1994;738:257‑264.

Christen WG, Jr. Antioxidants and eye disease. Am J Med 1994;97 Suppl. 3A:14S-17S.

Eye Disease Case-Control Group. Antioxidant status and neovascular age-related macular degeneration. Arch Opthomol 1993;111(1):104-9.

Gerster H. Antioxidant vitamins in cataract prevention. Z Ernahrungswiss 1989;28:56-75.

Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA 1994;272:1413-1420.

Snodderly DM, Evidence for protecting against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 1995;62:1448S-1461S.

Most of What Kills Us

Degenerative Diseases· Cancer· Heart Disease· Diabetes· Age Related Macular

Degeneration· Cataracts· The aging process itself!

“You’re not getting older, just your DNA”

(Headline from an article in Popular Science, August 2002, p.44)

Aging Symptoms

All Around Us

Sources:Sunlight, Stress, Toxins, Pollution,

X-rays, Radioactivity, Airline travel,

Medications

Metabolism – Calories & Oxygen (75K)

Smoking = 10 Billionfree radicals per cigarette!

The Solution

Antioxidants combat free

radicals to prevent cell damage and maintain health; we get

these from fruits, vegetables, and vitamin supplements

No one gets it

In a survey of 21,500 people, not a single person consumed a 100% of RDA for the 10 most important nutrients!

Did you eat 6-10 Servings* of Fruits and Vegetables Today?

*as recommended by the National Cancer Institute

June 19, 2002

“We recommend that ALL ADULTS take a multi-vitamin daily”

RDAs “Enough to prevent deficiency, but not enough to prevent disease”

You are now under doctors orders!

After decades, the American

Medical Association

does a 180º turn

After decades, the American

Medical Association

does a 180º turn

It is now Unanimous…

Which product?With so many choices, how do you know which Antioxidant supplements to buy?

How does a healthcare professional know what to recommend to their patients... and whether it works or not?

The Missing Link

The ability to MEASUREis the basis of SCIENCE

This has been the missinglink in the nutritional industry!

April 6, 1992

On Antioxidants vs. Free Radicals

…Antioxidants may one day revolutionize health care. …Screening people through a simple...test to assess how much damage free radicals have done to tissue, much as patients today are screened for high cholesterol.

Biochemist, William Pryor, director of theBiodynamics Institute at Louisiana State University

What if……

ANTIOXIDANT LASER SCANNER

“The Future” is NOW!

ANTIOXIDANT LASER SCANNER

MAKE NO MISTAKE:

There is nothing else like the

Protected by Patents

Key Patent issuedMarch 20, 2001

8 Patents Totalin the US,Europe and Asia

Global Exclusive Rights

acquired GlobalExclusive Rights

to this Technology from the U of U

for $110 Million....For the next 16 years!

Global Exclusive Rights

IT’S THE ONLY ONE OUT THERE.

This gives Pharmanex a

LEGAL MONOPOLY

Simple PhysicsA blue light laser is directed into the palm of your hand, and in about 3 minutes you see your total Antioxidant level... Non-invasively!

Site of Action

Only Pharmanex can measure at the

“Site of Action.” Cell Body:

Site of Action!

Blood and urine tests can be altered by a few meals.

It takes 4-6 weeks or longer for antioxidants to reach skin cells.

Brilliant Minds Endorse...Brilliant Minds Endorse...• Lester Packer – Antioxidant Miracle. Father of

antioxidants. “This validates my life’s work.”

• James Rippe, MD - Tufts, Boston (Cardiologist)

• James Balch, MD – author The Prescription for Nutritional Healing - 8 million copies sold

• Koji Nakanishi – Columbia, Discovered Ginkgo Biloba

• Carl Dierassi – Stanford, birth control pill.

• Chi - Huey Wong – Scripps Institute, appointed to the National Academy of Sciences

“Everyone should use the

Pharmanex Bio-Photonic

Scanner to learn their Optimal

Body Defense Score. Once you have your number, work to increase it and maintain it with a diet rich in fruits,

vegetables and vitamin supplements”

Lester Packer, PhD. UC Berkeley

As Quoted on CNN/Money.com

Everyone

Widely Acclaimed

•NBC

•CBS

•CNN Money

•Physician’s Desk Reference

•Logan College Of Chiropractic

•Much, much more.

Accepted by Scientific Community

• New York Academy of Sciences, Feb 2003• Oxygen Club of California, Feb 2003 and Feb 2004• FASEB/American Society of Nutritional Sciences - April 2003

and April 2004• Gordon Research Conference, Jan 2004• American College of Nutrition, October 2004

2005 American Business AwardsMOST INNOVATIVE PRODUCT

In the United States

ANTIOXIDANT LASER SCANNER

How do we RAISE our Antioxidant Score?

Eat Healthier4 Cups of Green Tea

50 Cups of Mangos

27 Cups of Green Peas

20 Small Apples

16 Large Potatoes

9 Cups of Cooked Rice

21 Slices of White Bread

14 Slices of Whole Wheat Bread

23 Cups of Pineapple

13 Medium Sized Bananas

65 Cups of Asparagus

30 Cups of Milk

10 Cups of Tomatoes

10 Tablespoons of Peanut Butter

59 Slices of Cheddar Cheese

11 ½ Cups of Peanuts

16 Cups of Squash

EVERY

DAY!

A better solution

OR TAKE LIFEPAK TWICE A DAY!

(Healthy eating and exercise are still a good idea)

Vitamin A,C, E, Selenium, ManganeseCopper, Zinc, Lutein

LycopeneAlpha-Lipoic Acid

Folic AcidPhytonutrients

QuercitinGrape Seed ExtractGreen Tea Extract

LifePak Antioxidants

A comprehensive, bioavailable nutritional wellness supplement

delivering the optimum amounts of all essential and

beneficial nutrients,

with Pharmaceutical-grade

testing and standardization.

What is LifePak?

NOT Just Another Multivitamin ....

“LifePak has been the subject of two clinical studies designed to assess the antioxidant benefits of the product – quite a significant fact when you consider that we know of NO other supplement companies that have sponsored clinical studies on their multivitamin products.”

“We applaud Pharmanex for their efforts in this regard.”

SupplementWatch rates LifePak #1!

SupplementWatch.com

Effect of LifePak Supplementation

19950

2685829463

33173

0

5000

10000

15000

20000

25000

30000

35000

40000

45000

Time (weeks)0 4 8 12

V. L

ow |

Low

| M

od.|

Hig

h

p < 0.01 p < 0.01

Individual Changes, Days 1-28

0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

40,000

45,000

Day 1 Day 28

n = 25

#1 Product

Top Revenue Supplement in the World

Top Supplement certified banned substance

free by the USOC

Shipped directly to each customer

20% - 30% rewards program every month!

G3

Gac juice (Momordica cochinchinensis)

Cili juice

Siberian Pineapple

Chinese Lycium

Ingredients

With Highly Bio-Available Lipocarotenes™

Beta-Carotene (mg/g wet wt.)

48 76 79

718

0

100

200

300

400

500

600

700

800

Spinach Carrot Sw.Potato Gac aril

Ishida et al., J Agric Food Chem 52:274, 2004

10 x morethan carrots!

Zeaxanthin in Chinese Lycium (mg/g wet wt.)

18

800

0100200300400500600700800900

1000

Yellow Corn Ch.Lycium

40 x more thanyellow corn!

Vitamin C in Cili Fruit (mg/100g wet wt.)

30 45 71

2500

0

500

1000

1500

2000

2500

Mandarin Orange Kiwi Cili

60 x morethan oranges!

Lycopene (mg/g wet wt.)

31 41 54

2227

0

500

1000

1500

2000

2500

Tomato Watermelon Guava Gac aril

Ishida et al., J Agric Food Chem 52:274, 2004

70 x morethan tomatoes!

Pharmanex controls the world-wide production of

Gac

and

Cili

Recorded Benefits• Increases energy• Anti-aging properties• Promotes eye health• Strengthens Immune System• Fights cancer• Improves circulation• Regulates cholesterol• Promotes Prostate health• Facilitates optimal bioavailability of key nutrients• Promotes skin health• Promotes vascular health• Promotes would healing• Protects skin from UV damage• Fights heart disease• Prevents stroke• Stabilizes blood pressure• Promotes better digestion• Promotes prostate health• Bolsters immune system• Promotes liver health• Eases headaches• Promotes sexual health• Promotes vitality

ABSOLUTE PROOF

Free re-scan every 30 days

100% Money Back Guarantee!

Only Pharmanex can provide on-going measurement and motivation to every patient!

FINALLY SOMEONE PUTS THEIR MONEY WHERE THEIR MOUTH IS!