Which ratio limits the size of cells? A. The rate of metabolism to mass B. The surface area to volume C. The mass to volume D. The surface area to mass Which statements are characteristics of diffusion through membranes? I. Polysaccharides can be transported. II. It can be facilitated by special channels. III. It is affected by concentration gradients. A. I and II only B. I and III only C. II and III only D. I, II and III Which statement is characteristic of tumours? A. They occur only in certain animal cells. B. They result from controlled cell division in only some organs. C. They result from uncontrolled cell division and occur in any organ. D. They result from partially controlled transcription. Identify the atoms and ions from the table below. Atoms Ions A. H + Na + OH – Cl –
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Which ratio limits the size of cells?
A. The rate of metabolism to mass
B. The surface area to volume
C. The mass to volume
D. The surface area to mass
Which statements are characteristics of diffusion through membranes?
I. Polysaccharides can be transported.
II. It can be facilitated by special channels.
III. It is affected by concentration gradients.
A. I and II only
B. I and III only
C. II and III only
D. I, II and III
Which statement is characteristic of tumours?
A. They occur only in certain animal cells.
B. They result from controlled cell division in only some organs.
C. They result from uncontrolled cell division and occur in any organ.
D. They result from partially controlled transcription.
Identify the atoms and ions from the table below.
Atoms Ions
A. H+ Na+ OH– Cl–
B. Fe K CH3COO– H2O
C. Fe H2O Ca2+ N3 –
D. Na C I– NO3 –
Which compounds are both organic and found in living organisms?
GlucoseC6H12O6
Carbon DioxideCO2
UreaOC(NH2)
Calcium CarbonateCaCO3
A.
B.
C.
D.
Key: = present = absent
What is an active site?
A. The part of an enzyme that binds only to the product molecules.
B. The sequence of amino acids responsible for the catalytic activity of enzymes.
C. The sequence of amino acids responsible for the structure of an enzyme.
D. The specific area responsible for the activity of all proteins.
hat is responsible for the conservation of the base sequence during DNA replication?
A. DNA polymerase working on one strand at the same time.
B. Unpaired bases always attracting their complementary nucleotides.
C. DNA helicase and polymerase are complementary.
D. Both strands are identical to each other.
Which graph shows the effect of increasing carbon dioxide concentration (CO2) on the rate of photosynthesis?
A.
B.
C.
D.
(Total 1 mark)
What are the components of a eukaryotic chromosome?
A. One DNA molecule and one large protein
B. Many DNA molecules and many proteins
C. One DNA molecule and many proteins
D. Many DNA molecules and one large protein
What is a karyotype?
A. Maternal and paternal autosomes arranged in pairs.
B. Chromosomes arranged in pairs according to the number of their genes.
C. Chromosomes arranged in pairs according to their size and shape.
D. Chromosomes arranged in pairs according to their size.
What is the cause of sickle cell anemia?
A. Errors in the translation of mRNA
B. A base substitution mutation in DNA
C. A transcription error that replaces A with U
D. A mutation that leads to glutamic acid instead of valine
What is the relationship between Mendel’s law of segregation and meiosis?
A. Only one of a pair of alleles appears in a gamete.
B. The separation of “paternal” and “maternal” chromosomes shows no pattern.
C. Gametes contain all dominant or all recessive alleles.
D. Variation only results from two divisions.
What are the possible applications of DNA profiling?
I. Solving paternity suits
II. Aiding certain criminal investigations
III. Identifying people who died last century
A. I only
B. I and II only
C. II and III only
D. I, II and III
What is natural selection?
A. The mechanism that increases the chance of certain individuals reproducing.
B. The mechanism that leads to increasing variation within a population.
C. The cumulative change in the heritable characteristics of a population.
D. The mechanism that explains why populations produce more offspring than the environment can support.
Why is most food digested?
A. Digestive enzymes require a variety of substrates.
B. It ensures that the diet is balanced.
C. Most ingested food molecules are large.
D. To prevent disorders of the intestine.
he diagram below shows the human heart. Which parts contain the most oxygenated blood?
A. P and T
B. Q, R and S
C. T, U, V and W
D. T, U, R and S
What is a pathogen?
A. A virus that causes a disease.
B. Any organism or virus that causes a disease.
C. A disease caused by bacteria or viruses.
D. Any organism transmitted from humans to humans.
hat are responsible for the lowering of blood glucose levels?
I. -cells in the pancreas
II. Insulin molecules
III. -cells in the pancreas
A. II only
B. I and II only
C. II and III only
D. I, II and III
Which fluid is sampled to try to detect chromosomal abnormalities in a fetus?
A. Placental
B. Umbilical
C. Amniotic
D. Spinal
Magellanic penguins (Spheniscus magellanicus) live and breed near the coast of Argentina. However, their colonies are a long way from the open sea where they hunt for fish. They cannot fly so have to swim to the feeding grounds. A study investigated how the water currents due to high and low tides affected their journey to and from their colonies. The results are shown below.
C u rren t fro m co lo n y
C u rren t to co lo n y
C u rren t fro m co lo n y
P engu ins / num ber
7 0
6 0
5 0
4 0
3 0
2 0
1 0
0 0 6 :0 0 1 2 :0 0 1 8 :0 0 2 2 :0 0 M o rn in g E v en in g
Tim e o f d a y / h o u r
K ey : d ep a rtin g fro m co lo n y a rriv in g a t c o lo n y
[Source: R. P. Wilson, “Magellanic Penguins Spheniscus magellanicus commuting through San Julian Bay;do current trends induce tidal tactics?”, Journal of Avian Biology (Oct 30 2003), vol. 32, issue 1, pp. 83-89.
a) Draw and label a simplified structure of a nucleotide.(2)
A genetic cross was made between pure-breeding snapdragon plants with red flowers and pure-breeding snapdragon plants with white flowers. The cross produced F1 offspring that had only pink flowers. When the F1 plants were self-pollinated, the resulting F2 generation had some red, some white and some pink flowers.
(b) (i) Identify the relationship between the red and white alleles for flower colour.
Up to two additional marks are available for the construction of your answers.(2)
(a) Draw and label a diagram of the carbon cycle.(5)
(b) Outline the mechanism of inhalation in human lungs.(5)
(c) Discuss the causes and effects of the greenhouse effect and ways to control it.
a) Draw and label a generalized prokaryotic cell as seen under the electron microscope.(4)
(b) Outline the process of meiosis.(6)
(c) Explain the role of the following hormones in the menstrual cycle: estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH).
a) Draw and label a diagram to illustrate the fluid mosaic model of biological membranes.(5)
(b) Using a table, compare aerobic and anaerobic respiration in a eukaryotic cell.(5)
(c) Explain the process of translation.
(a) Outline how impulses are transmitted between neurons.
he cyanobacterium (Calothrix elenkenii) is cultivated as a source of photosynthetic pigments for use in research and industry. The chart below shows the quantity of two of the pigments produced when exposed to a day of continuous dark, a day of 16 hours light and 8 hours dark and a day of continuous light. This was repeated in both aerobic and anaerobic conditions.
he phylogeny below shows how and when vertebrates could have evolved. The lines show when each lineage arose, split and in some cases became extinct.
[Source: http://evolution.Berkeley.edud/evosite/evo101/IIEAAddingtime.htmlUC Museum of Paleontology’s Understanding Evolution (http://evolution.berkeley.edu).]
(a) Identify how many years ago mammals split from birds and reptiles.
o determine whether bird song is innate or learned, songs of birds raised naturally were compared with the songs of those raised in isolation. Two species, the Swamp Sparrow (Melospiza georgiana) and the Song Sparrow (Melospiza melodia), were studied. The number of different songs the birds sang, the average number of syllables in the notes, the average length of the songs and the total number of notes were recorded.
N u m b ero f d iffe ren t
so n g s
1 2
1 0
8
6
4
2
0
N u m b er o f sy llab le s
1 81 61 41 21 0
86420
N o rm a l Iso la ted N o rm a l Iso la ted
S o n g len g th / s
3 .0
2 .5
2 .0
1 .5
1 .0
0 .5
0 .0
N u m b er o f n o te s p er
so n g
5 0
4 0
3 0
2 0
1 0
0 N o rm a l Iso la ted N o rm a l Iso la ted
K ey : S w am p S p a rro w S o n g S p a rro w
[Source: Peter Marler, Anais da Academia Brasilereira de Ciências, (2004), 76 (2), pages 189–200Adapted from Peter Marler, An Acad Bra Cienc, (2004), 76 (2), pages 189-200]
(a) Calculate the difference in the number of notes per song between the normal and isolated Swamp Sparrows.
onservationists noticed that the number of red squirrels (Sciurus vulgaris) in Wales was declining, and the number of a newly introduced species, the North American grey squirrel (Sciurus carolinensis), was increasing. In 1998, a project was started to reduce the number of grey squirrels in 244 hectares of woodland in Wales. The graph below shows the number of grey squirrels in 1998 and the number of red squirrels in 1999, 2000 and 2002. The data was collected at eight different sites (A–H).
S qu irre l d en s ity / n u m b er p e r hec ta re
(c) Discuss the hypothesis that decreasing the density of grey squirrels after 1999 led to an increase in the density of red squirrels in the following years.
(ii) 22:00 hours (evening) / 10 pm (units required) 1
(b) greatest number leaving in early morning / 6:00 hours / 6 am;reduces during midday / early afternoon / general decline from 6:00-16:00hours / 6 am-4 pm;increases slightly in evening / after 18:00 hours / 6 pm / 18:00-20:00hours / 6 pm-10 pm; 2 max
(c) (strongest) current to colony (so difficult to leave);current brings in food;long way to feeding grounds / long time feeding;all / many out at sea hunting;penguins resting; 2 max
(iii) grid with gametes shown correctly (CR and CW / other);all offspring genotypes shown; 2
(iv) 1 red:2 pink:1 white / 25% red : 50% pink : 25% white; 1
(c) fewer children with genetic disease / can prevent genetic disease;lower long-term health costs;frequency of harmful alleles reduced;allows early diagnosis / detection / confirmation of genetic disease;treatment can start for genetic disease;prepare (psychologically) parents for affected children;can predict (probability of) genetic disease; 2 max
(a) Award [1] for any of the following clearly drawn and correctlylabelled.plants taking in CO2 (making carbohydrates) in photosynthesis;
animals eating plants;animals / plants giving off CO2 by (cell) respiration;decomposers / micro-organisms giving off CO2 by (cell) respiration;fossilization of plant / animal parts / store carbon as fossil fuels;factories / cars giving off CO2 through combustion of fossil fuels;(dead) plants / animals to decomposers / saprotrophs; 5 max
(b) inhalation means air entering;external intercostal muscles contract;diaphragm contracts / flattens / moves downwards;thorax volume increases;creates pressure difference / lower pressure in thorax / lungs / correctreference to Boyles Law;air enters lungs / inhales air by nose and mouth; 5 max
Accept any of the above points if clearly explained in a labelled diagram.
(c) causes: [2 max]
increased CO2 levels (from combustion of fossil fuels by cars / transport);
effects: [3 max]higher levels of greenhouse gases increase the retention of heat reflectedfrom earth;cause increased temperatures of atmosphere / global warming;increase water evaporation / droughts / crop losses;increase melting of polar ice / glaciers / release of trapped methane;increased levels of sea / possible flooding of coastal areas;changing weather patterns / climatic extremes;
controls: [3 max]international measures to reduce combustion of fossil fuels (eg Kyotoconvention);reduce use of cars / combustion motors / smaller cars / drive less / lowerspeed limits / mass transit;reduce energy consumption / use low energy light bulbs / use betterinsulation in houses / increase use of electric cars;increased protection / restoration of ecosystems / reforestation;alternative energy sources (eg wind, solar, waves, nuclear);eat local food;feasible suggestion to increase photosynthesis / reduce CO2 (egspreading of nutrients in ocean to induce algae growth); 8 max
(Plus up to [2] for quality)
(a) Award [1] for any of the following clearly drawn and correctly labelled.
Award [2 max] if two or more eukaryotic structures are given and if a nucleusis included award [0].cell wall / capsule / slime wall / layer;plasma / cell membrane;mesosome,cytoplasm;ribosomes;nucleoid / naked DNA;flagella;pili;plasmid;size stated 1 to 10 μm; 4 max
(b) two cell divisions / reduction-division / diploid to haploid / meiosis Iand meiosis II;produce four (haploid) cells;for production of sex cells / gametes / spores;daughter cells are different from parent cells;homologous chromosomes / two chromatids pair up;line-up on equator;(spindle fibres) pull homologous chromosomes to opposite poles;two haploid cells are formed;second division / like mitosis, separates chromatids to opposite poles; 6 max
Accept any of the above points if clearly explained in alabelled diagram.
(c) FSH stimulates (in first few / five days) follicle development (in ovary);(FSH stimulates) follicles to secrete estrogen, (positive feedback);low levels of estrogen initially inhibit FSH (and LH) secretion;rapid increase in estrogen stimulates FSH / LH production, (positivefeedback);estrogen also starts to repair / thicken endometrium / uterine lining;LH stimulates ovulation;LH causes follicle to produce less estrogen (negative feedback) / moreprogesterone (positive feedback);LH stimulates follicle to become corpus luteum;corpus luteum secretes (more estrogen and) large level of progesterone(positive feedback);
estrogen and / or progesterone stimulate thickening of endometrium / uterus lining;estrogen and / or progesterone inhibit FSH and LH secretion (bynegative feedback);estrogen and / or progesterone levels fall after day 21-24 if no embryo / fertilization;lower concentrations of estrogen and / or progesterone allowdisintegration of endometrium / menstruation occurs;FSH secretion begins a new cycle; 8 max
Award [6 max] if only three hormones are explained.
(a) Award [1] for any of the following clearly drawn and correctly labelled.phospholipids (bilayer);
hydrophilic heads and hydrophobic tails;intrinsic / integral proteins / protein channels;glycoproteins / receptor proteins / glycolipids on outside;cholesterol embedded in membrane;extrinsic / peripheral proteins;thickness size 10 nm (0.1 μm); 5 max
(b) Award [1] for each correct row, up to [5 max].
large amount of ATP (36 per glucosemolecule) produced
small amount of ATP (2 per glucosemolecule) produced;
5 max
(c) messenger / mRNA attaches to ribosome (small unit);many ribosome / polyribosomes bind to same mRNA;carries codons / triplet of bases each coding for one amino acid;transfer / tRNA each have specific anticodon;triplet of bases for specific amino acid;tRNA carries specific amino acid;tRNA binds to ribosomes;to corresponding triplet base / codon;a second tRNA binds to next codon;two amino acids bind together;in a peptide linkage;first tRNA detaches;ribosome moves along mRNA;another tRNA binds to next codon;continues until polypeptide / protein formed to stop codon;stop codon has no corresponding tRNA / amino acid / causes releaseof polypeptide; 8 max
(Plus up to [2] for quality)[20]
(a) transmission occurs across a synapse;neurotransmitter released / moves across the synapse;influx of calcium ions;neurotransmitter destroyed;initiates transmission of impulse in second neuron; 2 max
(b) impulse is initiated in the motor area of the cerebral cortex;impulse travels from CNS to effector;impulse carried in the motor neurons;motor end plates of the neurons form synapse with muscle fibre;stimulate contraction of muscle fibres / actin and myosin in biceps;propioreceptors detect how stretched the muscle is;feedback to the brain; 3 max
(a) light dark 1
(b) %2001005.0
00.1
1
(c) dark has least of both pigments;light has most -carotene;light-dark has most chlorophyll;most total pigment in light;light dark is the only condition where more chlorophyll is made than -carotene; 2 max
(d) pigments absorb light for photosynthesis / absorption spectrum;more light absorbed more photosynthesis / action spectrum;different pigments absorb different wavelengths of light;can photosynthesize in different environmental conditions; 3 max
[7]
(a) 2 1
(b) matrix (fluid) 1
(c) Award [1] for each row, up to [3 max].
Respiration Photosynthesis
both make ATP;
both involve electron transport;
protons move against a concentration gradient in both;
both require ATP synthetase;
occurs in mitochondrion occurs in chloroplasts / thylakoids;
uses energy from oxidation uses energy from light;
has NADH for electron production
has water for electron production;
3 max
(a) 350 (10) million years (units required) 1
(b) fossil evidence 1
(c) dinosaurs are most recent reptiles to be separated from birds;some dinosaurs may have actually been birds;separation from birds may have come after warm blood evolved / commonancestor;some may have been warm blooded, others not;two lines show that different dinosaurs evolved at different times; 3 max
(d) all came from a common ancestor (less than 100 million years ago);continents divided isolating some;these evolved independently;first the ancestors of monotremes were isolated, then marsupials andplacental mammals divided;Australia separated and marsupials found there / other examples; 2 max
[7]
) 25 (1) 1
(b) Song Sparrow song always longer than Swamp Sparrow;isolation increases Song Sparrow song length but decreases SwampSparrow song length; 2
Answers may be numerical.
(c) a behaviour that occurs in all members of a species / behaviour determinedgenetically / inherited / stereotyped behaviour / not learnt / instinctive 1
(d) innate characteristics would be the same (or nearly the same) in normaland isolated;notes per song / number of songs very different so probably not innate;number of syllables / song length similar / not so different so possiblyinnate; 3 maxhypothesis not supported for all song characteristics;
(a) (i) osmoregulation / thermoregulation / hormone production 1
(ii) coordination of movement / balance / posture 1
(b) photoreceptor;receptor stimulated by light; 2
[4]
(a) 2002 1
(b) 6 / A B E F G H 1
(c) hypothesis seems to be supported;
in most / five sites the red squirrel density has increased since 1999;some sites decreased in density from 2000 to 2002;may be other factors controlling squirrel density;however there is no information about red squirrels in 1998 / more datais required starting with same density of grey squirrels in 1998 anddifferent densities of red squirrels; 3 max
(d) (principle of) competitive exclusion;competition occurs between them;most successful of the two increases in numbers;displaces the other from the population; 3 max
(b) organisms can occupy several different trophic levels;food sources may change / different diets at different times of the year;feeding habits can vary through an organism’s life cycle; 2 max
(c) roots break down rocks to form soil particles;roots prevent soil erosion by binding action of roots / erosion isincreased due toroots / burrowing / grazing animals;plants decompose returning minerals / humus / organic matter to soil;plants reduce wind;plants produce shade;lichens / mosses trap organic matter;soil structure improves as organic content rises / increasing waterretention / aeration;increase oxygenation of water due to photosynthesis / decreaseoxygenation of water due to decay;light intensity decreases due to leaf canopy; 3 max