d-LIVER Showcase Workshop Milano, May 2015 WEARABLE DEVICE FOR VITAL SIGNS MONITORING Frode Strisland d-LIVER Showcase Workshop Milano, May 27 th 2015 1
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d-LIVER Showcase Workshop
Milano, May 2015
WEARABLE DEVICE FOR VITAL SIGNS MONITORING
Frode Strislandd-LIVER Showcase Workshop
Milano, May 27th 2015
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d-LIVER Showcase Workshop
Milano, May 2015
d-LIVER Wearable Device:Continuous physiological monitoring of liver patients in home settings
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Objective: Develop device for continuous, ambulatory measurements of vital signs for early detection of patient exacerbations.
Main usage scenarios: Intermittent measurements during shorter time sequences (days-weeks-months), such as assessment of medical intervention effects.
1. Establish baseline at start a new treatment programme (such as d‒LIVER enrolment).
2. Lifestyle change, outcome assessment and patient motivational tool (lifestyle changes such as exercise, substance abuse, diet, etc.).
3. Assessment of effect of medication adjustments.
4. Monitoring requested by medical personnel for patient status assessment.
d-LIVER Showcase Workshop
Milano, May 2015
Wearable Device: Design Approach
Usability essential:
Mounted by patient
Worn for many hours
Liver patient skin issues
Development concerns
High quality electrodes needed for ICG measurements
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d-LIVER Showcase Workshop
Milano, May 2015
d-LIVER Wearable Device:
Target measurement parameters
Parameters selected based on clinical needs assessments within the project
• Heart rate
• Heart rate variability
• Skin temperature
• Activity level
• Step Counter
• Upper body posture
• Pulse transit time
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d-LIVER Showcase Workshop
Milano, May 2015
Wearable Device
System architecture
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d-LIVER Showcase Workshop
Milano, May 2015
Sensors used to calculate Pulse Transit Time to extract blood pressure
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Pulse Transit Time (PTT): The time it takes from the heart valve opens until the blood pressure wave reaches the periphery. PTT depends on blood pressure; the higher pressure, the shorter PTT.
Sensors used• Electro CardioGraphy (ECG) - Used to
detect the heartbeat start impulse• Impedance CardioGraphy (ICG) -
Used to detect opening of the aortic valves
• PhotoPlethysmoGraphy (PPG) - Used to detect the peripheral pressure wave
d-LIVER Showcase Workshop
Milano, May 2015
Wearable device
Communication configurations
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2. HDP IEEE
11073 agent
SpO2
1.Serial Port
Protocol
d-LIVER Showcase Workshop
Milano, May 2015
Wearable Device:
Status on clinical testing
Testing on healthyvolunteers (SINTEF)
Testing on 24 patientsalongside an ongoing NASH exercise study at University of Newcastle
d-LIVER system testing at Charité
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Testing scheduled
d-LIVER Showcase Workshop
Milano, May 2015
Acknowledgements
The d-LIVER project is partly funded by the European Commission (Contract No. 287596)
www.d-liver.eu
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