-
R E L E A S E N O T E S
ACQUITY, ACQUITY UPLC, Connections INSIGHT, Empower, MassLynx,
nanoACQUITY UPLC, “THE SCIENCE OF WHAT’S POSSIBLE.” and Waters are
registered trademarks and Auto•Blend Plus, eCord, LAC/E32, and
Q-Tof
are trademarks of Waters Corporation. All other trademarks are
the sole property of their respective owners.
Copyright 2013 Waters Corporation
Page 1 of 21
*716004096* *Rev.A*
Waters Driver Pack 4 Driver Pack 4 includes instrument drivers
and firmware required to control Waters instruments, as well as
helpful utility applications. The driver pack is compatible with
Empower® software, MassLynx® software, and specific, third-party
data systems. It is not compatible with ACQUITY UPLC® IVD-marked
systems.
The instrument drivers and firmware in Driver Pack 4 support
these ACQUITY UPLC systems:
• ACQUITY UPLC System
• ACQUITY UPLC H-Class System
• ACQUITY UPLC H-Class Bio System
• ACQUITY UPLC I-Class System
• ACQUITY UPLC Systems with 2D Technology
Driver Pack 4 updates the June 2011 Driver Pack. It contains
many new features and enhancements. See “What’s new in this
release” for detailed information about the improvements included
in Driver Pack 4.
For instructions about how to install Driver Pack 4, see Driver
Pack 4 Installation and Configuration Guide.
For information regarding the configuration of Empower
Enterprise networks, see Empower 3 Installation, Configuration, and
Upgrade Guide.
Table of Contents What’s new in this release
...................................................................................
2
Driver Pack 4 contents
.........................................................................................
4
Instrument driver and firmware
versions.............................................................
6
Supported Waters and third-party software
......................................................... 9
Defects addressed by this release
......................................................................
10
Known issues in this release
..............................................................................
17
Anti-virus considerations
...................................................................................
20
Requalification guidelines
..................................................................................
20
Contact Waters Technical Service
.......................................................................
21
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What’s new in this release Driver Pack 4 implements new
features, enhancements, and defect corrections to the instrument
drivers, firmware, and utility applications included in the driver
pack.
New features
Instrument or software component
Description
System You can now run multiple driver pack versions on a single
Empower Enterprise network. Previously, it was necessary to install
the same driver pack on all Empower LAC/E32 modules, Empower
clients, and Citrix servers on the network. Driver Pack 4, however,
can be installed on individual LAC/E32 modules, as long as it is
also installed on all of the Empower clients and Citrix® servers on
the network. This feature makes it possible to add new LAC/E32
modules to the network without upgrading and requalifying the
existing LAC/E32 modules. For further information see the Driver
Pack 4 Installation and Configuration Guide.
Deployment Manager New Verify Instrument Driver Files
application, to verify driver installation on non-Empower
systems.
BSM and CM-A 2D Repeat parameter added to instrument methods
allows the gradient table and timed-event table to repeat
throughout the run, allowing for two-dimensional
chromatography.
QSM
Flow rate range increased to 2.2 mL/min. Correspondingly, the
flow/pressure envelope is now:
• 15000 psi from 0 mL/min to 1 mL/min • 15000 psi to 7800 psi,
linear, from 1 mL/min to 2.2 mL/min
QSM Ability to import to and export from the solvent
library.
SM-FL and SM-FTN
New sample- compartment temperature test helps determine whether
the sample heater/cooler is operating within specifications. The
test can be found in the sample manager section of the console
software under the Troubleshoot menu. See the console software’s
online help for a description of this test.
SM-FTN Injection valve can now be cycled via the timed-event
table, to help reduce carryover.
Console Instrument driver versions on both the client and
server, as well as the installed driver versions and firmware
versions, now appear in the Help > About dialog.
Console Maintenance summaries for the BSM, CM/CM-A, QSM, SM,
SM-FL, and SM-FTN can be viewed and printed.
Utilities New application allows a single workstation to switch
between controlling an ACQUITY system and a nanoACQUITY®
system.
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Enhancements
Instrument or software component
Description
Deployment Manager Improved robustness and error handling
(better detection, logging, visibility).
Deployment Manager Improved compatibility with the Empower
Verify Files utility.
Multiple instruments Wide-area networks with latencies of up to
300 ms are now supported for the BSM, QSM, SM, SM-FL, SM-FTN, TUV
and PDA. High latency networks previously caused their instrument
drivers to freeze or terminate.
BSM When you run an Empower system that includes two BSMs, their
order in the console software tree now always matches that of the
Empower system definition.
QSM Prime function enhanced by the ability to prime to a
specific composition as well as apply a composition at the end of
the prime.
QSM The QSM method print content is enhanced to include the
buffer system details and the compositional percentages in
Auto•Blend Plus™ mode.
QSM The QSM will initiate the system’s inject start to trigger
any Ethernet detectors or column managers on its next intake stroke
after receiving an inject-start, contact-closure, rear-panel event.
This support permits operation without an ACQUITY Autosampler (SM,
SM-FTN, or SM-FL) in the system, allowing for control with external
devices.
QSM The QSM now supports a passive check valve option in
addition to Waters Intelligent Intake Valve (i2Valve) operation,
for use in certain applications.
SM-FTN Autoaddition capabilities improved with the addition of
the Mix Cycles and Mix Stroke Volume method parameters.
CM The column manager post-run report is extended to include the
part number, and any recorded eCord™ comments.
CM, CM-A The column manager now stops the solvent flow for any
change in selected column position. Previously, the flow would not
stop when pressure was less than 500 psi.
Utilities Columns Calculator gradients can now be
dragged-and-dropped to the BSM method editor.
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Driver Pack 4 contents The Driver Pack 4 DVD includes these
items:
• All current instrument drivers and firmware files for ACQUITY
UPLC instruments and detectors
• Utilities for use with ACQUITY UPLC systems
• Driver Pack 4 Deployment Manager
• ACQUITY UPLC Console
These supporting materials accompany the Driver Pack 4 DVD:
• Driver Pack 4 Installation and Configuration Guide on a
documentation CD
• Driver Pack 4 release notes
• Pointer card with information about Waters’ website
Instrument drivers and software components
Driver or software component Version
2489 Detector 1.31
2998 Detector 1.30
Binary Solvent Manager 1.60
Column Manager 1.60
Columns Calculator 1.60
Connections INSIGHT® 3.2
ELS Detector (also supports 2420 and 2424) 1.40
FLR Detector 1.40
Local Console Controller 1.60
PDA Detector 1.60
Quaternary Solvent Manager 1.60
RI Detector 1.40
Sample Manager 1.60
Sample Manager-FTN 1.60
TUV Detector 1.60
Waters Pump Control Software 3.10
Waters SQ Detector 1.41
Waters TQ Detector 1.41
Deployment Manager 3.1
ICS Companion 1.60
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Firmware
Firmware (SFT files) Version Checksum
2420 Detector 1.30 0x21A5BED0
2424 Detector 1.30 0x21A5B8D0
2489 Detector 1.41 0xBD0669D0
2998 Detector 1.41 0xEDB36196
Binary Solvent Manager 1.60 0x36F220A9
Column Manager (Active) 1.60 0x1B55819D
Column Manager 1.40.74 0x8E9D1DC0
ELS Detector 1.40 0x216F9370
FLR Detector 1.42 0xD99DEFB5
PDA Detector (1) 1.60 0xF7ED509A
PDA Detector (2) 1.60 0xDCFE9340
Quaternary Solvent Manager 1.60 0xA9C8E138
RI Detector 1.40 0xAA39BF4C
Sample Manager 1.60 0x47F616CE
Sample Manager-FL 1.60 0x37CC5868
Sample Manager-FTN 1.60 0x35D5392B
Sample Organizer 1.60 0x96FA9AB0
TUV Detector (1) 1.60 0xBC170FAF
TUV Detector (2) 1.60 0xD71E0EDA
Note: The installers for the ELS, FLR, RI, 2489, and 2998
detectors have been updated to address installation issues. Because
their version numbers changed, they appear as upgrades during
installation. Nevertheless the files they install remain identical
to the currently released versions. Performing upgrades of those
components is therefore harmless.
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Instrument driver and firmware versions
ACQUITY UPLC System
Modules Part number Software version Firmware version
ACQUITY UPLC BSM 186015001 Binary Solvent Manager, v1.60
Binary Solvent Manager, v1.60
ACQUITY UPLC SM 186015005, 186015006
Sample Manager, v1.60
Sample Manager, v1.60
ACQUITY UPLC HTCH 186015010 N/A N/A
ACQUITY UPLC Column Heater N/A N/A N/A
ACQUITY UPLC CM 186015007 186015009
Column Manager, v1.60
Column Manager, v1.40.74
ACQUITY UPLC Column Heater/Cooler
186015008 N/A N/A
ACQUITY UPLC H-Class and H-Class Bio Systems
Modules Part number Software version Firmware version
ACQUITY UPLC H-Class QSM/ H-Class Bio QSM
186015018, 186015041
Quaternary Solvent Manager, v1.60
Quaternary Solvent Manager, v1.60
ACQUITY UPLC H-Class SM-FTN / H-Class Bio SM-FTN
186015017, 186015040
Sample Manager-FTN, v1.60
Sample Manager-FTN, v1.60
ACQUITY UPLC H-Class CH-A / H-Class Bio CH-A
186015042 N/A N/A
ACQUITY UPLC H-Class CM-A / H-Class Bio CM-A
186015043 Column Manager, v1.60
Column Manager (Active), v1.60
ACQUITY UPLC H-Class CM-Aux / H-Class Bio CM-Aux
186015049 N/A N/A
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ACQUITY UPLC I-Class System
Modules Part number Software version Firmware version
ACQUITY UPLC I-Class BSM 186015000 Binary Solvent Manager,
v1.60
Binary Solvent Manager, v1.60
ACQUITY UPLC I-Class SM-FTN 186015046 Sample Manager-FTN,
v1.60
Sample Manager-FTN, v1.60
ACQUITY UPLC I-Class SM-FL 186015060 Sample Manager, v1.60
Sample Manager-FL, v1.60
ACQUITY UPLC I-Class CH-A 186015042 N/A N/A
ACQUITY UPLC I-Class CM-A 186015043 Column Manager, v1.60
Column Manager (Active), v1.60
Detectors
Modules Compatible systems Part number Software version Firmware
version
ACQUITY UPLC TUV All UPLC systems 186015028 TUV Detector,
v1.60
TUV Detector (1), v1.60
ACQUITY UPLC TUV Thermally Enhanced
All UPLC systems 186015031 TUV Detector, v1.60
TUV Detector (2), v1.60
ACQUITY UPLC PDA All UPLC systems 186015026 PDA Detector,
v1.60
PDA Detector (1), v1.60
ACQUITY UPLC PDA Thermally Enhanced
All UPLC systems 186015032 PDA Detector, v1.60
PDA Detector (2), v1.60
ACQUITY UPLC ePDA All UPLC systems 186015030 PDA Detector,
v1.60
PDA Detector (1), v1.60
ACQUITY UPLC ePDA Thermally Enhanced
All UPLC systems 186015033 PDA Detector, v1.60
PDA Detector (2), v1.60
ACQUITY UPLC FLR All UPLC systems 186015029 FLR Detector,
v1.40
FLR Detector, v1.42
ACQUITY UPLC ELS All UPLC systems 186015027 ELS Detector,
v1.40
ELS Detector, v1.40
Waters 2420 ELS Detector
Waters HPLC Systems
186002420 ELS Detector, v1.40
2420 Detector, v1.30
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Waters 2424 ELS Detector
Waters HPLC Systems
186002424 ELS Detector, v1.40
2424 Detector, v1.30
Waters 2489 UV/Visible Detector
Waters HPLC Systems
186002487 2489 Detector, v1.31
2489 Detector, v1.41
Waters 2998 PDA Detector
Waters HPLC Systems
186002998 2998 Detector, v1.30
2998 Detector, v1.41
SQ Detector All UPLC systems 176000872 Waters SQ Detector,
v1.41
N/A
TQ Detector All UPLC systems 176001263 Waters TQ Detector,
v1.41
N/A
Other system modules
Modules Compatible Systems Part Number Software Version Firmware
Version
Sample Organizer ACQUITY UPLC Systems 186015014186015020
186015021
SM, v1.60 or SM-FTN, v1.60 or SM-FL, v1.60
Sample Organizer, v1.60
ACQUITY UPLC 30-cm Column Heater/Cooler
All UPLC Systems 186015011 N/A N/A
ACQUITY UPLC CH-30A ACQUITY UPLC I-Class / ACQUITY UPLC H-Class
and H-Class Bio Systems
186015045 N/A N/A
Column Manager Auxiliary Units
ACQUITY UPLC H-Class and H-Class Bio Systems
186015049 N/A N/A
Local Console Controller
All UPLC systems 725000464 Included with all Driver Pack 4
instrument drivers
N/A
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Supported Waters and third-party software The table below shows
which Waters and third-party software operate with ACQUITY UPLC
systems.
System Empower 2: base release to SP H Hotfix 1
Empower 3: base release to FR2
MassLynx (see list of SCNs, below)
Standalone ACQUITY Console
Analyst® (see note, below)
ACQUITY UPLC System (including 2D)
Yes Yes Yes Yes Version 1.6.2
ACQUITY UPLC H-Class System (including 2D)
Yes Yes Yes Yes Version 1.6.2
ACQUITY UPLC H-Class Bio System (including 2D)
Yes Yes Yes Yes Version 1.6.2
ACQUITY UPLC I-Class System (including 2D)
Yes Yes Yes Yes Version 1.6.2
See also: Contact the appropriate vendor for compatibility
information about other third-party control software.
The following MassLynx SCNs are compatible with this
release:
SCN 781, SCN 802, SCN 822, SCN 835, SCN 849, SCN 855, SCN 869,
SCN 870, SCN 872, SCN 873, SCN 876, SCN 882, SCN 883, SCN 884, SCN
888, and SCN 896.
Requirement: If an SQ, TQ, or 3100 detector is part of the
system, you must install, at a minimum, Empower 2 Feature Release
4. Note that the Empower 2 System Suitability option is
required.
Note: Analyst supports 2D, but only with UPLC solvent managers
that differ, such as one QSM and one BSM.
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Defects addressed by this release The table below lists software
problems that Driver Pack 4 addresses. The software change request
(SCR) numbers in the left-hand column identify problems that Waters
monitors in its change request database. The right-hand column
describes changes in Driver Pack 4.
The improvements listed below take effect if you install Driver
Pack 4 on both the Empower client, and on the LAC/E32 module. If
you install Driver Pack 4 on the Empower client, but run an earlier
Driver Pack version on the LAC/E32 module, some of the improvements
do not take effect.
General
SCR number Instrument or software component
Description
25496 Console Equilibrations can once again be run in the
standalone console software with a CM in the system.
25684 Console Pressure plots are now displayed in the units
(psi, bar, kPa) selected by the user, rather than always psi.
26496 Console When exporting multiple plot channels, the time
base for the channels is now synchronized. Previously the time base
of each channel could differ slightly, making plot comparison
difficult.
26650 Console The pressure units selected for display in the
console software now apply only to the current Windows user.
Previously the pressure unit selection applied to all Windows
users.
24545 Deployment Manager
The Local Console Controller driver can now be upgraded without
affecting the BSM or CM instrument drivers.
24546 Deployment Manager
Fully installing the PDA instrument driver while upgrading other
drivers no longer causes a blank PDA method editor.
24596 Deployment Manager
The Local Console Controller driver can now be upgraded without
affecting the ELS or FLR drivers.
24873, 25970 Deployment Manager
The Empower Verify Files utility now displays the correct
version number for the ELS instrument driver.
24954 Deployment Manager
The BSM instrument driver no longer corrupts the nanoACQUITY BSM
instrument driver when they are installed on the same computer.
25791 Deployment Manager
The ICS Companion utility now runs correctly after installation
on Citrix servers.
26348 Deployment Manager
The Java runtime engine (JRE) is now installed only if
Connections INSIGHT is also installed.
23855 Waters DHCP Server
The Waters DHCP Server is modified to offer DHCP addresses only
on the instrument LAN, not all network cards.
26288, 26289 Solvent Library The solvent library no longer
allows multiple solvent aliases of the same name, a practice that
can cause it to stop working.
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SCR number Instrument or software component
Description
24538 Column Calculator
Japanese version of the Columns Calculator utility correctly
shows L/Dp ratio.
24486 Multiple instruments
Warning level alarms, such as “Drawing sample rate excessive”,
no longer cause memory leaks.
26046 Multiple instruments
Systems with five or more instruments no longer cause a
"Database error: unable to continue" error in Empower.
26357 Multiple instruments
Statistical data displayed in post-run reports, such as Maximum
System Pressure, is now calculated correctly even without enabling
a data channel in the associated instrument’s method.
26777 Multiple instruments
Previously, when two of the same type of instrument were
included in a system (for example, two BSMs) the instrument method
for both instruments would display the same values in the method
editor, even if the values of one method were changed. Now both
instrument methods can have unique values.
28178, 26840, 28178
Multiple instruments
When the Empower system definition includes multiple instruments
of the same type – for example, two BSMs – their relative
precedence now carries through to the console software. The BSM
listed first in the Empower system definition now consistently
appears first in the console software tree, and so on. This
relative order is most meaningful elsewhere in the console
software, where a simple numerical suffix, such as the “2” in
“BSM2”, differentiates instruments of the same type.
This change pertains only to instruments of the same type. For
instruments that differ in type, the precedence rules of the
console software still apply to the order of the instruments
displayed in the console software tree. For example, solvent
managers come first, followed by sample managers and then
detectors.
Previously, for systems that include two PDA detectors in
previous driver packs, instrument status obtained for just one of
the detectors showed identically in both PDA control panels. This
defect is corrected.
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Solvent managers
SCR number Instrument or software component
Description
24160 BSM Previously, the BSM control panel occasionally failed
to properly appear on some Empower Enterprise systems. The defect
is corrected.
24164 BSM Previously, the BSM was vulnerable to an erroneous
“Pump motor lost synchronization” error and shutdown when running
specific gradients with a 100% composition. The defect is
corrected.
25860 BSM Previously, the BSM would stop priming if there was an
associated column change. The defect is corrected.
25964 BSM Previously, the BSM did not fully stop the solvent
flow if you specified doing so when the current flow rate was 0.01
mL/min. You can now fully stop a flow of 0.01 mL/min.
25010 QSM Previously, the QSM lost its leak detector
configuration after a power cycle. The defect is corrected.
25352 QSM Previously, an error occurred under certain
circumstances in the recommended pH range when you used the
Auto•Blend Plus function. The defect is corrected.
25354 QSM Previously, curves 1 and 11 appeared in the method
editor’s graphical gradient representation as curve 6 (linear). The
defect is corrected.
26290 QSM The QSM leak test now properly primes the
user-selected solvent, rather than always priming with the “A”
solvent.
27351 QSM Previously, the QSM might not completely reach a
requested 0.000 mL/min flow rate when slower method flow rate
accelerations were specified. The defect is corrected.
27815 QSM Stop flow buttons on the console software and control
panel now operate properly when flow is < 0.01 mL/min.
28210 QSM The QSM to FTN system leak test has been modified to
work successfully with larger (≥ 100 μL) extension loops.
28580, 28579 QSM Previously, a QSM pump could randomly cause a
general failure error, especially with regard to applications in
which flow rate or pressure changes rapidly, such as those that
require starting and stopping the pump during a column change. The
defect is corrected.
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Sample managers
SCR number Instrument or software component
Description
24888, 26945 SM Previously, the XY mechanism move-needle
functionality in the console software did not move the needle. The
defect is corrected.
24595 SM, SM-FL Previously, the characterize Needle Seal
diagnostic test showed incorrect values after calibration.
25033 SM, SM-FL Previously, the results of the Calibrate XY and
Zp Axes diagnostic test failed to appear in the console software’s
log.
28002 SM, SM-FL Previously, in Empower software, the Run Samples
“Needle Wash” sample queue function failed. The defect is
corrected.
29432 SM, SM-FL, SM-FTN
Previously, during diagnostic tests, the sample manager failed
to reliably warn of impending mechanical movements. The defect is
corrected.
Sample organizer
SCR number Instrument or software component
Description
24552 SO Previously, the sample organizer’s LED lights failed to
switch off when the door was closed, which could affect
light-sensitive samples. The defect is corrected.
24936 SO Previously, the sample organizer might not be visible
in the console software. The defect is corrected.
26077 SO Previously, the shelf position immediately below the
transfer location was not accessible in the sample organizer. The
defect is corrected.
26811 SO Error recovery is improved along with users’ ability to
properly reset the sample organizer.
27620 SO Previously, the sample organizer’s configuration could
be lost whenever the computer was restarted.
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Column managers
SCR number Instrument or software component
Description
24582 CM-A The status of the CM-A leak sensor is now properly
displayed.
25589 CM-A Previously an error “Preheater temperature sensor
hardware fault” was possible if the column temperature was set to
~90.0 without first stabilizing at a lower temperature. The defect
is corrected.
25645 CM, CM-A Previously, the eCord injection count and column
history data was incorrectly updated in MassLynx open-architecture
systems. The defect is corrected.
25981 CM-A The CM-A’s advanced-mode valve timing is improved to
allow for more simultaneous valve operations.
26088 CM Previously, the column history for Column 6 did not
appear properly in the console software. The defect is
corrected.
26359 CM, CM-A Previously, it was possible for eCord data to be
incorrectly written to the device. The defect is corrected.
26431 CM-A Previously, the console software did not always adapt
the list of available CM-A diagnostic channels according to
supported hardware options or operating mode. The defect is
corrected.
28444 CM-A Previously, column switching errors were possible
when transitioning between sample-queue and instrument-method
column switching.
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Third party software
SCR number Instrument or software component
Description
24612 Analyst Previously, after loading the June 2011 driver
pack, ACQUITY parameter settings appeared in Analyst acquisition
methods, on the Software Application Properties tab. The defect is
corrected.
25447, 25448 Analyst Previously, after loading the June 2011
driver pack on Windows 7, 64-bit machine, Analyst was unable to
load plates. The defect is corrected.
26116 Analyst System correctly collects data after a disabling
or enabling the hardware profile. You must run StopProcesses before
enabling a hardware profile.
26118 Analyst Configuring the module in the console software
correctly updates ACQUITY method editor. Rebooting is required.
26353 Analyst Column switching causes brief, expected flow delay
in I-Class system under Analyst control.
26683 Analyst ACQUITY AAO Service automatically restarts when
the service stops working. The primary purpose of this improvement
is to support StopAcquityProcesses and StopProcesses.
26917 Analyst In mixed security mode, you can reliably log off
and log back on. In integrated security mode, you cannot log off
the computer while a batch is running.
Detectors
SCR number Instrument or software component
Description
24523 PDA A small PDA memory leak that could cause problems if
allowed to accumulate over thousands of injections is
eliminated.
24813 TUV Improved error detection and management of interrupted
communications, which could have resulted in an unexpected change
in data rate.
24996 PDA Improved PDA error detection to guard against possible
data overruns, should communications to the PDA be interrupted for
an extended period of time.
25065 PDA Channel name and description for MaxPlot and other
complex, calculated channels, such as sum, difference, and ratio,
are improved to show proper values and ranges.
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SCR number Instrument or software component
Description
25453 TUV Previously, a possible error involving the TUV method
editor permitted saving a corrupt method, which can produce an
incorrect data rate on the second channel. The defect is
corrected.
25487 2998 Previously, the 2998 detector experienced data
saturation or produced an incorrect auto exposure when
next-injection delays exceed a duration of ten minutes. The defect
is corrected.
25831 PDA The PDA exposure calculation has been corrected to
account for timed event wavelength changes to spectral regions of
higher energy. Previously, it was possible for an incorrect
exposure time to be calculated and executed, which could result in
peak area discrepancies.
25911 TUV Previously, the leak sensors in some older-model TUVs
failed to function. The defect is corrected.
26036 TUV Shutter idle configuration is correctly refreshed, and
accurately shows current state.
26942 PDA Previously, the 2998 server sometimes stopped working
on startup or during resets of the server while under the control
of MassLynx software. The defect is corrected.
29197 PDA Internal fans operate reliably when the detector is
powered up in “Maximum cooling mode”.
26681, 26111 PDA Previously, under some circumstances, changing
the PDA lamp could cause the console software to stop working. The
defect is corrected.
26129, 26130 PDA, TUV Improved PDA and TUV lamp and flow-cell ID
communications, to reduce the likelihood of false identification
failures.
28272, 28273, 28279, 28280
PDA, TUV Previously, when you changed a lamp, its memory device
sometimes recorded incorrect data (hours, date, and time). The
defect is corrected.
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Known issues in this release The table below lists known
software issues in Driver Pack 4. Waters’ change request database
uses the software change request (SCR) numbers in the left-hand
column to track these issues.
SCR number Instruments or software components
Description
24809 SO If, in the console software, you disable the Z-motor
and then move the Z-axis manually, the device begins to beep and
flash its front-panel LED.
Workaround: To recover, reset the device.
24905 2489 detector It is possible that the 2489 can experience
a filter initialization failure in high temperature and humidity
environments when calibrating.
Workaround: Filter initialization under varying temperature and
humidity conditions is optimized. If filter initialization fails,
reboot the instrument to retry the initialization.
25485 Analyst To ensure successful data acquisition, Analyst
control requires methods to specify the same data rate.
25560 Deployment Manager
Occasionally the ICSCompanion service is not installed during
normal installation.
Workaround: Using the Deployment Manager, perform a typical
removal, reboot the computer, and then perform the installation
again.
26118 Console After you specify which instruments will appear in
the console software, the method editor displays the previously
specified instruments.
Workaround: Reboot the computer after changing the instrument
configuration in the console software.
26620 TUV The TUV’s rear-panel switch output, or outputs, can
momentarily pulse with each method setup on each injection, causing
an extra valve movement if the outputs are used to control external
valves.
27495 Waters Pump Control
It is possible that using the Windows Control Panel to uninstall
Waters Pump Control software released prior to Driver Pack 4 does
not remove all files.
Workaround: Uninstall Waters Pump Control using the Driver Pack
4 Deployment Manager.
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SCR number Instruments or software components
Description
27753 Local Console Controller (LCC), ELS, FLR
During an upgrade from the 1.40 Driver Pack, if the Local
Console Controller is being upgraded, the ELS and FLR detectors
must be upgraded as well, to avoid failures of the ELS and FLR
instrument drivers.
27842 CM The Column Manager page in the console software can
sometimes display the message "No Function Text".
Workaround: Ignore the message.
28235 Verify Instrument Driver Files
If the Windows User Account Control (UAC) function is enabled,
you must be logged in as an administrator to run the Verify
Instrument Driver Files utility.
28394 Console Closing the console software after initiating the
System Startup function cancels the function and resets the system
modules.
Workaround: Do not close the console software until the System
Startup function is completed.
28917 Autoloader The Autoloader can sometimes attempt to load
BSM firmware on the nanoBSM device.
Workaround: Power-off all connected nanoACQUITY modules before
beginning an installation.
29135 Deployment Manager
Installing older instrument drivers can occasionally cause
deletion of the Empower Verify Files checksumshell.bat file.
Workaround: During installation and removal, the Deployment
Manager creates a backup of checksumshell.bat in the
“C:\Empower\Instruments\Logs” folder. If checksumshell.bat is
deleted, it can be restored from that location to “C:\Empower”.
29253 SM-FL Clearing the Disable Motors option in the console
software does not re-enable motors.
Workaround: Reset the instrument via the console software to
re-enable the motors.
29300 FLR Aborting FLR diagnostic tests sometimes prevents them
from being rerun.
Workaround: Reboot instrument.
29374 Waters Pump Control
Waters Pump Control (WPC) 3.10 is not compatible with
nanoACQUITY 1.42.
Workaround: If you run nanoACQUITY along with Driver Pack 4,
choose a Custom installation in the Deployment Manager, and then
deselect WPC 3.10 before you install.
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SCR number Instruments or software components
Description
29395 ELS, FLR, RI, 2998 Although other Driver Pack 4
instruments support networks with latencies as high as 300
milliseconds, in some cases the ELS, FLR, RI, and 2998 do not.
Performance will therefore vary.
29422 SM Resuming an Empower sample set after an SM error can
result in the erroneous message “Waiting for injection”.
Workaround: Abort and restart sample set.
29494 Verify Files The Verify Instrument Driver Files utility
can display script errors with Internet Explorer 8 installed.
Workaround: Install Microsoft hotfix KB2416400.
29497 Connection INSIGHT
When you upgrade from the June 2011 Driver Pack to Driver Pack 4
on Windows 7, Connections INSIGHT® installation fails
occasionally.
Workaround: Remove Connections INSIGHT, reboot the computer,
install Connections INSIGHT.
29539 2D system In a MassLynx system using 515(s) with a PCM, it
can be necessary to reboot the computer after changing the MassLynx
instrument configuration.
29618 Autoloader The Autoloader can stop working if run on a
LAC/E32 module connected to an e2695 separations module.
Workaround: Reboot a LAC/E32 module connected to an e2695
separations module before running the Autoloader.
29670 QSM The QSM instrument driver must be upgraded when
upgrading other instrument drivers to Driver Pack 4, otherwise the
Auto•Blend Plus feature, specified in the method editor, will stop
working.
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Anti-virus considerations If you are using real-time virus
scanning, exclude the data system and instruments folders and
sub-folders as shown below. Some real-time virus scanners can
mistake normal data acquisition and instrument control for virus
activity and thus interfere with proper operations. Full-system
scans and live updates can be network-intensive, disk-intensive,
and CPU-intensive, and they can also interfere with normal data
acquisition. Schedule scans and updates for idle times when data
acquisition does not occur.
Exclude these folders:
• For Empower 2 and Empower 3 installations, the Empower
installation folder, usually “C:\Empower”, and its sub-folders.
• For MassLynx installations,
• “C:\Program Files\Waters Instruments”, and its sub-folders
(“C:\Program Files (x86)\Waters Instruments” on 64-bit
machines).
• the MassLynx installation folder, usually “C:\Masslynx”, and
its sub-folders.
• For standalone console software and other third party
installations, “C:\Program Files\Waters Instruments”, and its
sub-folders (“C:\Program Files (x86)\Waters Instruments” on 64-bit
machines).
Certain anti-virus program features like "intrusion prevention"
and "tamper protection" can also interfere with normal operation.
Disable them as well.
Requalification guidelines Driver Pack 4 includes instrument
driver software and firmware used on your laboratory instruments,
servers, and workstations. As with any change in a regulated
environment, follow your organization's standard operating
procedures for managing software changes.
This update has been designed not to alter the physical
specifications of the instrument(s) or system(s), and Waters
believes that methods run and data generated on instruments before
and after the update will be identical.
However, after a risk based review of the changes detailed in
the release notes, users in a regulated environment may need to
consider and document what, if any, requalification of the
instrument modules, the chromatographic system, and/or the
Chromatographic Data System (CDS) are required by their own change
control SOPs.
Use the appropriate qualification methods outlined below to
verify installation and correct operation:
• To confirm that the driver pack installation has not
negatively affected any critical system functions, and that the new
files have loaded properly, you may consider performing a software
Installation Qualification (IQ). To confirm the firmware files
installed on the modules are correctly installed, compare the
checksum values in the product release notes to the checksum values
displayed in the console.
• To confirm an instrument's operation with the newly loaded
driver software and firmware, you may consider performing an
Operational Qualification (OQ) for the updated instrument or
system.
• To confirm performance, control, and communications of the
instruments in your system, you should consider conducting a
Performance Qualification (PQ) (user or vendor PQ) or System
Suitability test.
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Where multiple identical systems are involved, a risk based
approach to qualification activities may be an important
consideration.
Requalifying the instrument driver software, firmware, and
hardware when upgrading is covered under the Total Assurance Plan
with System Qualification Option in the following cases:
• During yearly requalification under the plan.
• If loading this release is required for operation of a new
module or system, where qualification of the new module or system
is covered under the plan.
Requalification of the CDS software and computers after a driver
upgrade may or may not be included in Assurance Plans from the CDS
vendor.
Review your Total Assurance Plan to determine which services are
covered, and which are not covered. For situations not covered
under the plan, Waters can still perform the qualification, but
additional charges apply.
Contact Waters Technical Service If you are located in the USA
or Canada, report malfunctions or other problems to Waters
Technical Service (800 252-4752). If you are located elsewhere,
phone the Waters corporate headquarters in Milford, Massachusetts
(USA), or contact your local Waters subsidiary. Our Web site
includes phone numbers and e-mail addresses for Waters locations
worldwide.
What’s new in this releaseDriver Pack 4 contentsInstrument
driver and firmware versionsSupported Waters and third-party
softwareDefects addressed by this releaseKnown issues in this
releaseAnti-virus considerationsRequalification guidelinesContact
Waters Technical Service