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Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0

Aug 14, 2020

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Page 1: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0
Page 2: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0
Page 3: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0
Page 4: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0
Page 5: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0

0

1x107

2x107

0

1x10 7

2x10 7

02x10 84x10 86x10 8

0.0

5.0x106

1.0x10 7

0.0

5.0x10 6

1.0x10 7

0

1x10 8

2x10 8

0.0

5.0x106

1.0x107

0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0

-0.0010

-0.0005

0.0000

0.0005

0.0010

0.0015

0.0020

0.0025

0.0030

0.0035

0.0040

0.0045

0.0050

min

min0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0

338.1 m/zDihydro berberine

340.3 m/zCanadine

336.1 m/z Berberine

370.1 m/z Isocorypalmine

398.4 m/z Methyl hydrastine

384.1 m/zHydrastine

352.2 m/z Palmatine

384.1

398.4

336.1

370.1

340.3

352.2

338.1

300 nm UV

Page 6: Waters Corporation · 0 1x107 2x107 0 1x107 2x107 0 2x108 4x108 6x108 0.0 5.0x106 1.0x107 0.0 5.0x106 1.0x107 0 1x108 2x108 0.0 5.0x106 1.0x107 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0